37,211 results match your criteria pedal dermatoses

Sorafenib-related generalized eruptive keratoacanthomas (Grzybowski syndrome): a case report.

J Med Case Rep 2021 Sep 21;15(1):481. Epub 2021 Sep 21.

Flinders Centre for Innovation in Cancer, Flinders Medical Centre, Adelaide, South Australia, Australia.

Background: Sorafenib is an oral multikinase inhibitor that targets Raf serine/threonine receptor tyrosine kinases and inhibits tumor cell growth and angiogenesis. Cutaneous toxicities of sorafenib are common, including cutaneous eruptions (such as truncal erythema and seborrheic-dermatitis-like changes) and hand-foot syndrome. Keratoacanthomas and squamous cell carcinomas have been reported previously; however, we report a case of multiple eruptive keratoacanthomas in the form of Grzybowski syndrome after initiation of sorafenib. Read More

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September 2021


Wiad Lek 2021 ;74(8):1891-1893


Objective: The aim: To conduct a comparative analysis of clinical data, laboratory results, and pain intensity in patients using developed by us device for offloading the foot and plaster splint during inpatient treatment of purulent-necrotic complications of diabetic foot syndrome.

Patients And Methods: Materials and methods: We examined 76 patients with purulent-necrotic complications of diabetic foot syndrome, who used a plaster splint and a device for offloading the foot. We evaluated the clinical indicators of the healing process, laboratory data and pain intensity. Read More

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September 2021

Talaromyces stipitatus, a novel agent causing superficial mycosis in a diabetic patient from North India.

Microbes Infect 2021 Sep 15:104887. Epub 2021 Sep 15.

Department of Botany, University of Jammu, Jammu, Jammu and Kashmir, 180006, India. Electronic address:

Among millions of reported fungal species, only a few hundred species are capable of causing diseases in humans and animals that range from superficial to life-threatening infections. Both immunocompetent as well as immunocompromised patients with underlying diseases, such as AIDS, diabetes, etc., are at higher risk of acquiring fungal infections. Read More

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September 2021

Ineffective peripheral tissue perfusion in patients with diabetic foot: a mid-range theory.

Rev Bras Enferm 2021 10;74(4):e20210113. Epub 2021 Sep 10.

Universidade Federal do Maranhão. Imperatriz, Maranhão, Brazil.

Objective: to develop a mid-range theory for nursing diagnosis ineffective peripheral tissue perfusion in patients with diabetic foot.

Method: the theory construction was carried out in six stages: approach definition; theoretical-conceptual model definition; definition of the main concepts; pictogram development; construction of propositions and establishment of causal relationships evidence for practice.

Results: twelve etiological factors and 22 clinical indicators were included in the theory, some of which were not listed in NANDA International (Inc. Read More

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September 2021

Melanoma of the Hands and Feet (With Reconstruction).

Clin Plast Surg 2021 Oct 27;48(4):687-698. Epub 2021 Jun 27.

Division of Plastic Surgery, Southern Illinois University School of Medicine, 747 N Rutledge Street #3, Springfield, IL 62702, USA.

Melanomas only account for 4% of all dermatologic cancers yet are responsible for 80% of deaths. Notably, melanomas of the hand and foot have a worse prognosis when compared with melanomas of other anatomic regions. Likely this is due to intrinsic biologic characteristics, delayed diagnosis, difficult surgical excision due to delicate anatomy, and lack of definitive diagnostic and therapeutic guidelines. Read More

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October 2021

A neonate with Klippel-Trénaunay syndrome: a case report.

J Med Case Rep 2021 Sep 7;15(1):447. Epub 2021 Sep 7.

Department of Surgery, Faculty of Clinical Medicine and Dentistry, Kampala International University Western Campus, Ishaka-Bushenyi, Uganda.

Background: Klippel-Trénaunay syndrome is a rare congenital capillary-lymphatic-venous condition characterized by the clinical triad of capillary malformations (port wine stains), varicose veins with or without venous malformations, and bony and/or soft-tissue hypertrophy. It has a very low incidence of about 1:100,000.

Case Presentation: We report the case of 21-day-old neonate Black African female (born in Uganda) with Klippel-Trénaunay syndrome who presented with macrodactyly and ectrodactyly on the left foot, as well as numerous port wine stains on the left thoracoabdominal region and anteroposterior left lower limb. Read More

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September 2021

Staged surgical management of sinus tarsi syndrome: our experience of 273 cases.

Ann Palliat Med 2021 Aug;10(8):8909-8918

Department of Orthopedics, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Background: The sinus tarsi syndrome (STS) is a common foot and ankle disease with controversial pathogenesis and treatment procedures. This long-term study aimed to analyze the effect of a staged surgical strategy for STS.

Methods: Clinical data were retrospectively analyzed in 273 STS patients [129 men and 144 women; mean age: 36 years (10-60 years)] treated between 2006 and 2016. Read More

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A Zigzag Flap for Correcting a Nail Deformity Caused by Subungual Schwannoma.

J Am Podiatr Med Assoc 2021 Jul;111(4)

Subungual schwannoma is quite rare and often causes nail deformity and difficulty in wearing shoes. Complete tumor excision is the treatment of choice, and we advocate that restoring the nail appearance should be considered at the same time. We present the case of 43-year-old man with a big toe subungual schwannoma. Read More

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Amputation versus Primary Nonoperative Management of Chronic Osteomyelitis Involving a Pedal Digit in Diabetic Patients.

J Am Podiatr Med Assoc 2021 Jul;111(4)

Background: The preferred primary treatment of toe osteomyelitis in diabetic patients is controversial. We compared the outcome of primary nonoperative antibiotic treatment versus digital amputation in patients with diabetes-related chronic digital osteomyelitis.

Methods: We conducted a retrospective medical record review of patients treated for digital osteomyelitis at a single center. Read More

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Healing Rate of Diabetic Foot Wounds When Treated with Serial Debridement in the Presence of Antithrombotic Therapy.

Jack Route

J Am Podiatr Med Assoc 2021 Jul;111(4)

Background: Previous study indicates that pharmacologic antithrombotic therapy may be an inhibitory factor for wound healing and should merit consideration among the other core factors in wound healing optimization.

Methods: This study provides a retrospective analysis of the effect of antithrombotic therapy on wound healing rates of uncomplicated diabetic foot ulcerations. Wounds treated with standard of care in the presence of clinical anticoagulation were compared to control wounds. Read More

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Pathological findings in African buffaloes (Syncerus caffer) in South Africa.

J S Afr Vet Assoc 2021 Aug 17;92(0):e1-e11. Epub 2021 Aug 17.

Department of Pathobiology, Zoological Pathology Program, University of Illinois, Illinois.

The African buffalo (Syncerus caffer) is an iconic species of South African megafauna. As the farmed buffalo population expands, the potential impacts on population health and disease transmission warrant investigation. A retrospective study of skin biopsy and necropsy samples from 429 animals was performed to assess the spectrum of conditions seen in buffaloes in South Africa. Read More

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Protocol for a prospective observational study: the Australia and New Zealand Diabetic and Ischaemic Foot Outcomes Study (ANZ-DIFOS).

BMJ Open 2021 09 2;11(9):e050833. Epub 2021 Sep 2.

Department of Surgery, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

Introduction: Diabetic foot disease is a common condition globally and is over-represented in indigenous populations. The propensity for patients with diabetic foot disease to undergo minor or major limb amputation is a concern. Diabetic foot disease and lower limb amputation are debilitating for patients and have a substantial financial impact on health services. Read More

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September 2021

[Analysis of clinical research outcome indicators of traditional Chinese medicine in treatment of diabetic foot].

Zhongguo Zhong Yao Za Zhi 2021 Aug;46(15):4008-4015

Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences Beijing 100091, China.

To analyze the outcome indicators from the randomized controlled trials(RCTs) on traditional Chinese medicine(TCM) treatment for diabetic foot, and to lay a foundation for the establishment of the core index set of the clinical trials on TCM treatment of diabetic foot. Computer retrieval of RCTs on TCM treatment of diabetic foot was performed in CNKI, Wanfang, SinoMed, PubMed, Cochrane Library, EMbase and Web of Science databases. Literature screening and data extraction were conducted independently by two researchers in strict accordance with inclusion and exclusion criteria. Read More

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Catching Fire: Are Operating Room Fires a Concern in Orthopedics?

J Patient Saf 2021 Aug 30. Epub 2021 Aug 30.

From the Department of Orthopedic Surgery, University of Alabama at Birmingham, Birmingham, Alabama Department of Orthopedic Surgery, University of Mississippi, Oxford, Mississippi .

Objective: Operating room (OR) fires are considered "never events," but approximately 650 events occur annually in the United States. Our aim was to detail fires occurring during orthopedic procedures via a questionnaire because of the limited information present on this topic.

Methods: A 25-question survey on witnessing surgical fires, hospital policies on surgical fires, and surgeons' perspective on OR fires was sent to 617 orthopedic surgeons in 18 institutions whose residency program is a member of the Collaborative Orthopaedic Educational Research Group. Read More

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Analysis of patients' rehabilitation results after surgical treatment of diabetes complications.

Pol Merkur Lekarski 2021 Aug;49(292):269-272

I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine: Department of Operative Surgery and Clinical Anatomy.

The results of treatment of patients with diabetic foot syndrome (DFS) remain unsatisfactory, 34% of patients have another wound defect in the foot within 1 year, and the recurrence rate within 5 years is 70%.

Aim: The aim of the study was to determine the indicators of physical capabilities and self-care of patients after organ-sparing surgery due to DFS.

Materials And Methods: 6-12 months after discharge from the surgical hospital, all patients were sent questionnaires of the functional scale of the lower extremities. Read More

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Associations between Nutrients and Foot Ulceration in Diabetes: A Systematic Review.

Nutrients 2021 Jul 27;13(8). Epub 2021 Jul 27.

Department of Diabetes and Endocrinology, Blacktown-Mt Druitt Hospital, Blacktown, NSW 2148, Australia.

We reviewed the literature to evaluate potential associations between vitamins, nutrients, nutritional status or nutritional interventions and presence or healing of foot ulceration in diabetes. Embase, Medline, PubMed, and the Cochrane Library were searched for studies published prior to September 2020. We assessed eligible studies for the association between nutritional status or interventions and foot ulcers. Read More

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Clinical Classification of the Diabetic Foot Syndrome Adapted to ICD-10 as a Solution to the Problem of Diagnostics, Statistics and Standardisation.

Medicina (Kaunas) 2021 Aug 11;57(8). Epub 2021 Aug 11.

Department of Polyclinic Therapy, Perm State Medical University, 614990 Perm, Russia.

: To propose a new classification of diabetic foot syndrome adapted for inclusion in the ICD-10 (the ICD-10 is the 10th revision of the International Statistical Classification of Diseases) and providing more reliable data on the number of clinical cases. : A randomized controlled trial was performed. A total of 180 patients (36. Read More

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A Case of Recurrent Malignant Melanoma of the Left Foot with In-Transit Metastases.

R I Med J (2013) 2021 Sep 1;104(7):42-45. Epub 2021 Sep 1.

surgical oncologist and a Clinical Assistant Professor of Surgery at the Warren Alpert Medical School of Brown University, Providence, RI. He also is the Director of the Breast Health Program at Roger Williams Medical Center, Providence, RI.

We report a 73-year-old male with recurrent amelanotic malignant melanoma of the left foot with in-transit metastases to the left thigh. In-transit metastatic melanoma can often represent a diagnostic and therapeutic challenge for physicians. This patient was treated with talimogene laherparepvec injections (T-VEC; Imlygic) in the left inguinal and the left plantar region every two weeks for one year as oncolytic viral therapy for advanced non- operable malignant melanoma. Read More

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September 2021

Terminal Syme Amputation of the Great Toe in the Pediatric Population.

J Pediatr Orthop 2021 Oct;41(9):e823-e827

Shriners Hospitals for Children.

Background: In the pediatric population, chronic ingrown toenails (onychocryptosis) can cause infection (paronychia), debilitating pain, and may be unresponsive to conservative treatments. Following multiple failed interventions, a terminal Syme amputation is one option for definitive treatment of chronic onychocryptosis. This procedure involves amputation of the distal aspect of the distal phalanx of the great toe with complete removal of the nail bed and germinal center, preventing further nail growth and recurrence. Read More

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October 2021

Foot rash and joint pain.

J Fam Pract 2021 Jun;70(5):249-251

University of Texas Health at San Antonio.

An untreated infection led to a series of unusual signs and symptoms that included difficulty walking. Read More

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Analytical and Early Detection System of Infectious Diseases and Animal Health Status in Kuwait.

Front Vet Sci 2021 29;8:676661. Epub 2021 Jul 29.

Environment and Life Sciences Research Center, Kuwait Institute for Scientific Research, Kuwait City, Kuwait.

This study aimed at the development of an analytic web-based system for the assessment of animal health in Kuwait. The data sources were based on the World Organization for Animal Health (OIE) and the World Animal Health Information System (WAHIS) repository with data gathered for the period (2005-2020). An on-line web-based system using TABLEAU Creator was developed for monitoring and surveillance of animal disease outbreaks. Read More

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Acute Limb Ischemia Caused by Inadvertent Arterial Drug Self-Injection: A Case Report.

Am J Case Rep 2021 Aug 15;22:e932903. Epub 2021 Aug 15.

Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.

BACKGROUND A predictable consequence of long-term injection drug use is the destruction of the native venous system; as a consequence, people who inject drugs may eventually move to injection into skin and subcutaneous tissue, wounds, muscles, and arteries. These practices put people who inject drugs at risk for injection-related soft-tissue infection, vascular damage, ischemia, and compartment syndrome, all of which have overlapping presenting symptoms. CASE REPORT A 35-year-old man who injects drugs presented with foot swelling and discoloration initially concerning for necrotizing fasciitis or compartment syndrome. Read More

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[Treatment of severe diabetic foot ulcer using tibia transverse transport combined with nose ring drain].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Aug;35(8):984-988

Department of Bone and Joint Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning Guangxi, 530021, P.R.China.

Objective: To investigate the effectiveness of tibial transverse transport (TTT) combined with nose ring drain (NRD) in the treatment of severe diabetic foot ulcer.

Methods: The clinical data of 60 patients with severe diabetic foot (Wagner grade 3 or 4) ulcer who were admitted between April 2017 and August 2020 and met the selection criteria were retrospectively analyzed. Among them, 30 cases were treated with TTT combined with NRD (TTT+NRD group), and 30 cases were treated with TTT (TTT group). Read More

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Peripheral arterial disease in patients with renal-diabetic foot ulcers.

J Wound Care 2021 Aug;30(8):660-664

Diabetic Foot Unit, Department of Systems Medicine, University of Rome 'Tor Vergata', Italy.

Objective: To describe the angiographic characteristics of peripheral arterial disease (PAD) in persons with diabetic foot ulcers (DFUs) on dialysis treatment.

Method: The study is a retrospective analysis of patients with DFUs and PAD who had been referred to our diabetic foot clinic. All patients had been managed by a pre-set limb salvage protocol including revascularisation of the affected limb. Read More

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Hard-to-heal wound treated with Integra Flowable Wound Matrix: analysis and clinical observations.

J Wound Care 2021 Aug;30(8):644-652

Department of Integrated Multi-Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.

Skin healing defects severely impair the quality of life of millions of people and burden healthcare systems globally. The therapeutic approach to these pathologies still represents a challenge. Novel scaffolds, used as dermal substitutes, possibly represent a promising strategy in complex wound management. Read More

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People living with diabetes are unaware of their foot risk status or why they are referred to a multidisciplinary foot team.

J Wound Care 2021 Aug;30(8):598-603

Diabetes Foot Clinic, King's College Hospital, London, UK.

Aim: People with active diabetic foot disease should be rapidly referred by health professionals along a pathway of care to a multidisciplinary foot team. The aim was to investigate patients' self-reported understanding of their foot risk status and reasons for their referral to a multidisciplinary foot team.

Method: This seven-month service evaluation included consecutive newly referred patients. Read More

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Evaluation of methanolic crude extract of Linum usitatissimum for the removal of biofilm in diabetic foot isolates.

Braz J Biol 2021 6;83:e245807. Epub 2021 Aug 6.

Imran Idrees College of Pharmacy, Sialkot, Pakistan.

Linum usitatissimum L is a widely used traditionally for multiple ailments. The present research was carried out to explore the antimicrobial, and anti-biofilm activity of crude extract of Linum usitatissimum L (Lu. Cr). Read More

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Foot care practice and associated factors among patients with lymphoedema in Boreda district, Gamo zone, southern Ethiopia, 2020. Implications for elimination of podoconiosis and lymphatic filariasis.

J Foot Ankle Res 2021 Aug 10;14(1):51. Epub 2021 Aug 10.

Collaborative research and training centre for neglected tropical diseases, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Background: Lymphatic filariasis is ranked as the second leading cause of disability world-wide. The current global programme to eliminate lymphatic filariasis is based on the interruption of transmission and the alleviation of disability and suffering.

Objective: to assess foot care practice and associated factors among lymphoedema patients in Boreda district, Gamo zone Southern Ethiopia. Read More

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The microbiology of diabetic foot infections: a meta-analysis.

BMC Infect Dis 2021 Aug 9;21(1):770. Epub 2021 Aug 9.

Infection Medicine, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.

Background: Diabetic foot ulcers are a common complication of poorly controlled diabetes and often become infected, termed diabetic foot infection. There have been numerous studies of the microbiology of diabetic foot infection but no meta-analysis has provided a global overview of these data. This meta-analysis aimed to investigate the prevalence of bacteria isolated from diabetic foot infections using studies of any design which reported diabetic foot infection culture results. Read More

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Georgian Med News 2021 Jun(315):7-9

3Clinica Goldman and Hospital Moinhos de Vento, Porto Alegre/ RS, Brazil.

Solid-cystic hidradenoma is a benign cutaneous tumor that is most commonly found in the head, neck, trunk, and upper extremity regions of patients in the middle to older aged groups. Presentation on lower extremities and in particular on the foot is uncommon. Nodular hidradenomas represent a dermatological pitfall, being difficult to differentiate from basal cell carcinoma and melanoma. Read More

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