196 results match your criteria pcm exposure

Comparative analysis of the combined petrosal and the pretemporal transcavernous anterior petrosal approach to the petroclival region.

J Neurosurg 2021 Sep 10:1-12. Epub 2021 Sep 10.

1Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona; and.

Objective: The combined petrosal (CP) approach has been traditionally used to resect petroclival meningioma (PCM). The pretemporal transcavernous anterior petrosal (PTAP) approach has emerged as an alternative. A quantitative comparison of both approaches has not been made. Read More

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September 2021

Phase-change mesoporous Prussian blue nanoparticles for loading paclitaxel and chemo-photothermal therapy of cancer.

Colloids Surf B Biointerfaces 2021 Aug 4;207:112018. Epub 2021 Aug 4.

Department of Pharmaceutics, Shenyang Pharmaceutical University, No.103, Wenhua Road, Shenyang, 110016, China. Electronic address:

Complete treatment of cancer remains a major challenge today. Herein, a biocompatible drug delivery system named as PCM + [email protected]/PEG was constructed. In this system, Paclitaxel (PTX) was blended with phase-change material (PCM) and loaded in mesoporous Prussian blue nanoparticles (mPBs), and chelated with polyethylene glycol at surface. Read More

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Exposure to Criticism Modulates Left but Not Right Amygdala Functional Connectivity in Healthy Adolescents: Individual Influences of Perceived and Self-Criticism.

Front Psychiatry 2021 6;12:673805. Epub 2021 Jul 6.

Ghent Experimental Psychiatry (GHEP) Lab, Department of Head and Skin, UZ Gent/Universiteit Gent, Ghent, Belgium.

Frequent exposure to criticism is a known risk factor for various adult psychiatric disorders. Adolescents may be even more vulnerable to (parental) criticism, as their imbalanced brain maturation makes them prone to stronger mood changes and less effective emotional regulation. Identifying which adolescent subgroups are more vulnerable than others could be of great clinical relevance. Read More

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Development of rapid and highly accurate method to measure concentration of fibers in atmosphere using artificial intelligence and scanning electron microscopy.

J Occup Health 2021 Jan;63(1):e12238

National Environmental Research and Training Institute, Ministry of the Environment Government of Japan, Tokorozawa, Saitama, Japan.

Aim: We aimed to develop a measurement method that can count fibers rapidly by scanning electron microscopy equipped with an artificial intelligence image recognition system (AI-SEM), detecting thin fibers which cannot be observed by a conventional phase contrast microscopy (PCM) method.

Methods: We created a simulation sampling filter of airborne fibers using water-filtered chrysotile (white asbestos). A total of 108 images was taken of the samples at a 5 kV accelerating voltage with 10 000X magnification scanning electron microscopy (SEM). Read More

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January 2021

Potential airborne asbestos exposures in dentistry: a comprehensive review and risk assessment.

Crit Rev Toxicol 2021 04 1;51(4):301-327. Epub 2021 Jun 1.

Cardno ChemRisk, San Francisco, CA, USA.

Chrysotile was formerly used in the manufacture of casting ring liner (CRL) and periodontal dressing powder (PDP). The purpose of this study was to describe the potential for airborne asbestos exposure among dental professionals who may have used these products and to assess their risk of asbestos-related disease (ARD). Task-specific exposure data associated with CRL and PDP were identified and compared to regulatory standards for asbestos and health-based benchmarks. Read More

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Sucrose exposure during gestation lactation and postweaning periods increases the pubococcygeus muscle reflex activity in adult male rats.

Int J Impot Res 2021 May 25. Epub 2021 May 25.

Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala, Tlaxcala, México.

Erectile dysfunction is related to metabolic alterations produced by a high carbohydrate diet, which may affect muscle activity during penile reflex in adulthood. We determined whether sucrose water consumption during gestation lactation and postweaning affects pubococcygeus muscle (Pcm) activity during urethrogenital reflex in adult male rat offspring. Twelve female rats were mated and grouped in control mothers consumed tap water and sucrose mothers consumed sucrose water during gestation lactation. Read More

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Safety and efficacy of a feed additive consisting on the bacteriophages PCM F/00069, PCM F/00070, PCM F/00071 and PCM F/00097 infecting Gallinarum B/00111 (Bafasal) for all avian species (Proteon Pharmaceuticals S.A.).

EFSA J 2021 May 17;19(5):e06534. Epub 2021 May 17.

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive consisting of four bacteriophages infecting Gallinarum B/00111 (PCM F/00069, PCM F/00070, PCM F/00071 and PCM F/00097, trade name: Bafasal) when used as a zootechnical additive in water for drinking and liquid complementary feed for all avian species. The effects sought are the reduction of the spp. carriage in chickens for fattening, the improvement of their performance, or both. Read More

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Developmental toxicity of procymidone to larval zebrafish based on physiological and transcriptomic analysis.

Comp Biochem Physiol C Toxicol Pharmacol 2021 Oct 15;248:109081. Epub 2021 May 15.

College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address:

As a broad-spectrum with low toxicity, procymidone (PCM), is widely used in agriculture and frequently observed in aquatic system, which may cause some impacts on aquatic organisms. Here, to determine the developmental toxicity of PCM, embryonic and larval zebrafish were exposed to PCM at 0, 1, 10, 100 μg/L in dehydrogenated natural water containing 0.01% acetone for 7 days. Read More

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October 2021

Evaluating the airborne asbestos dispersion in enclosed parking lots in Iran.

Arch Environ Occup Health 2021 May 17:1-9. Epub 2021 May 17.

Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Each time a car's brakes are used, asbestos is dispersed in the air. Breathing the air in enclosed parking lots can expose people working in these places to asbestos. This study aimed to evaluate the airborne asbestos dispersion in enclosed parking lots. Read More

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Deep Learning-Based Denoising in High-Speed Portable Reflectance Confocal Microscopy.

Lasers Surg Med 2021 08 23;53(6):880-891. Epub 2021 Apr 23.

College of Optical Sciences, University of Arizona, Tucson, Arizona, 85721.

Background And Objective: Portable confocal microscopy (PCM) is a low-cost reflectance confocal microscopy technique that can visualize cellular details of human skin in vivo. When PCM images are acquired with a short exposure time to reduce motion blur and enable real-time 3D imaging, the signal-to-noise ratio (SNR) is decreased significantly, which poses challenges in reliably analyzing cellular features. In this paper, we evaluated deep learning (DL)-based approach for reducing noise in PCM images acquired with a short exposure time. Read More

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Nanomaterials and hepatic disease: toxicokinetics, disease types, intrinsic mechanisms, liver susceptibility, and influencing factors.

J Nanobiotechnology 2021 Apr 16;19(1):108. Epub 2021 Apr 16.

Stomatological Hospital, Southern Medical University, Guangzhou, 510280, China.

The widespread use of nanomaterials (NMs) has raised concerns that exposure to them may introduce potential risks to the human body and environment. The liver is the main target organ for NMs. Hepatotoxic effects caused by NMs have been observed in recent studies but have not been linked to liver disease, and the intrinsic mechanisms are poorly elucidated. Read More

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Paracoccidioidesbrasiliensis induces IL-32 and is controlled by IL-15/IL-32/vitamin D pathway in vitro.

Microb Pathog 2021 May 23;154:104864. Epub 2021 Mar 23.

Laboratório de Imunidade Natural (LIN), Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil. Electronic address:

Paracoccidioidomycosis (PCM) is a systemic fungal disease caused by Paracoccidioides spp., whose clinical outcome depends on immune response. Interleukin 32 (IL-32) is a cytokine present in inflammatory and infectious diseases, including bacterial, virus and protozoan infections. Read More

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Airborne concentrations of chrysotile asbestos during operation of industrial crane controls and maintenance of associated arc chutes.

Toxicol Ind Health 2021 Mar 28;37(3):124-133. Epub 2021 Jan 28.

Center for Health Sciences, 107654Exponent, Inc., Menlo Park, CA, USA.

Some industrial crane control panels were historically equipped with chrysotile-containing arc chutes. Because of the paucity of data regarding potential exposure from such equipment, we used a simulation approach to quantify the release of chrysotile from arc chutes in two functional 1970s-era industrial crane control panels during operation and maintenance. Two experienced operators separately simulated operation of crane controls under load; one of these operators then simulated two arc chute maintenance protocols: sanding (protocol 1) and scraping, sanding, and blowing (protocol 2). Read More

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Survival and malformations rates, oxidative status in early life stages of Cyprinus carpio due to exposure to environmentally realistic concentrations of paracetamol.

Sci Total Environ 2021 May 9;768:144585. Epub 2021 Jan 9.

Laboratorio de Toxicología Acuática, Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Unidad Profesional Adolfo López Mateos, Av. Wilfrido Massieu s/n y cerrada Manuel Stampa, Col. Industrial Vallejo, Ciudad de México CP, 07700, Mexico.

Paracetamol (PCM) is among the most consumed analgesic and antipyretic drugs worldwide. Due to its high consumption, this drug has been reported ubiquitously on different water bodies, posing a real threat to aquatic organisms. Until now, several studies have pointed out that PCM may induce oxidative stress, histological damage and developmental disorders on different aquatic species. Read More

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Lipid droplet biogenesis and COX-2 pathway activation are triggered by Barrett's esophagus and adenocarcinoma, but not esophageal squamous cell carcinoma risk factors.

Sci Rep 2021 01 13;11(1):981. Epub 2021 Jan 13.

Molecular Carcinogenesis Program (PCM), Research Coordination (CPQ), Brazilian National Cancer Institute (INCA), Rua André Cavalcanti, 37-Centro, 6º andar, Rio de Janeiro, RJ, CEP 20231-050, Brazil.

Esophageal cancer (EC) is an aggressive disease, presenting two main histological subtypes: adenocarcinoma (EAC) and squamous cell carcinoma (ESCC). The two EC subtypes widely differ concerning virtually all factors. ESCC development is mainly associated with tobacco and alcohol abuse, whereas obesity and chronic gastroesophageal reflux disease (GERD) are important risk factors not only for EAC, but also for for Barrett's esophagus (BE), an intestinal metaplasia that precedes EAC. Read More

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January 2021

Long-term spaceflight and the cardiovascular system.

Precis Clin Med 2020 Dec 16;3(4):284-291. Epub 2020 Jun 16.

The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, 1305 York Avenue, New York, NY 10021, USA.

While early investigations into the physiological effects of spaceflight suggest the body's ability to reversibly adapt, the corresponding effects of long-term spaceflight (>6 months) are much less conclusive. Prolonged exposure to microgravity and radiation yields profound effects on the cardiovascular system, including a massive cephalad fluid translocation and altered arterial pressure, which attenuate blood pressure regulatory mechanisms and increase cardiac output. Also, central venous pressure decreases as a result of the loss of venous compression. Read More

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December 2020

Spatio-seasonal variation, distribution, levels, and risk assessment of airborne asbestos concentration in the most industrial city of Iran: effect of meteorological factors.

Environ Sci Pollut Res Int 2021 Apr 2;28(13):16434-16446. Epub 2021 Jan 2.

Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

Like other dangerous pollutants in the air, asbestos has negative and adverse effects on human and animal health. The present study is designed to determine the concentration of asbestos in the air of the most industrial city of Iran (Karaj) in 2018-2019. For this purpose, 4 samples were taken from different areas of the air of Karaj during a year with an SKC pump and flow of 6 L/min for 8 h and in 45 days, and a total of 68 samples of asbestos fibers were collected. Read More

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Probl Radiac Med Radiobiol 2020 Dec;25:490-501

State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», 53 Yuriia Illienka St., Kyiv, 04050, Ukraine.

Objective: Assessment of role of the bone marrow colony-forming efficiency in plasma cell myeloma patients at different stages of treatment as a prognostic criterion for the disease course.

Materials And Methods: The colony forming efficiency (CFE) was assayed in stage I-II plasma cell myeloma (PCM)patients (n = 37) aged 42-73, namely in patients survived after the Chornobyl NPP accident (n = 21) and persons notexposed to ionizing radiation (n = 16). There were 11 males exposed to ionizing radiation and having got stage I PCM,9 males and 3 females exposed and having got stage II PCM, 3 males and 3 females not exposed and having got stageI PCM, 6 males and 2 females not exposed and having got stage II PCM. Read More

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December 2020

Prediction of Conserved Peptides of for Interferon-γ Release Assay: The First Step in the Development of a Lab-Based Approach for Immunological Assessment during Antifungal Therapy.

J Fungi (Basel) 2020 Dec 19;6(4). Epub 2020 Dec 19.

Faculdade de Medicina, Universidade Federal do Mato Grosso do Sul, Campo Grande 79070-900, MS, Brazil.

Impaired antigen-specific cell-mediated immunity (CMI) is a primary immunological disturbance observed in individuals that develop paracoccidioidomycosis (PCM) after exposure to spp. Restoration of -specific CMI is crucial to stop the antifungal treatment and avoid relapses. A convenient and specific laboratory tool to assess antigen specific CMI is required for the appropriate clinical treatment of fungal infections, in order to decrease the time of antifungal therapy. Read More

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December 2020

Interaction of Isocitrate Lyase with Proteins Involved in the Energetic Metabolism in .

J Fungi (Basel) 2020 Nov 23;6(4). Epub 2020 Nov 23.

Laboratório de Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia 74690-900, Goiás, Brazil.

Background: Systemic mycosis is a cause of death of immunocompromised subjects. The treatment directed to evade fungal pathogens shows severe limitations, such as time of drug exposure and side effects. The paracoccidioidomycosis (PCM) treatment depends on the severity of the infection and may last from months to years. Read More

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November 2020

Passive Cavitation Mapping by Cavitation Source Localization From Aperture-Domain Signals-Part II: Phantom and In Vivo Experiments.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 04 26;68(4):1198-1212. Epub 2021 Mar 26.

Passive cavitation mapping (PCM) techniques typically utilize a time-exposure acoustic (TEA) approach, where the received radio frequency data are beamformed, squared, and integrated over time. Such PCM-TEA cavitation maps typically suffer from long-tail artifacts and poor axial resolution with pulse-echo diagnostic arrays. Here, we utilize a recently developed PCM technique based on cavitation source localization (CSL), which fits a hyperbolic function to the received cavitation wavefront. Read More

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Passive Cavitation Mapping by Cavitation Source Localization From Aperture-Domain Signals-Part I: Theory and Validation Through Simulations.

IEEE Trans Ultrason Ferroelectr Freq Control 2021 04 26;68(4):1184-1197. Epub 2021 Mar 26.

Passive cavitation mapping (PCM) algorithms for diagnostic ultrasound arrays based on time exposure acoustics (TEA) exhibit poor axial resolution, which is in part due to the diffraction-limited point spread function of the imaging system and poor rejection by the delay-and-sum beamformer. In this article, we adapt a method for speed of sound estimation to be utilized as a cavitation source localization (CSL) approach. This method utilizes a hyperbolic fit to the arrival times of the cavitation signals in the aperture domain, and the coefficients of the fit are related to the position of the cavitation source. Read More

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Planktonic- and Biofilm-Conditioned Media Elicit Discrete Metabolic Responses in Human Macrophages.

Cells 2020 10 9;9(10). Epub 2020 Oct 9.

Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA.

Macrophages (MΦs) are prevalent innate immune cells, present throughout human bodily tissues where they orchestrate innate and adaptive immune responses to maintain cellular homeostasis. MΦs have the capacity to display a wide array of functional phenotypes due to different microenvironmental cues, particularly soluble bacterial secretory products. Recent evidence has emerged demonstrating that metabolism supports MΦ function and plasticity, in addition to energy and biomolecular precursor production. Read More

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October 2020

Thermal Load of Mine Rescuer in the Underwear and Protective Clothing with Phase Change Materials in Simulated Utility Conditions.

Materials (Basel) 2020 Sep 28;13(19). Epub 2020 Sep 28.

Department of Personal Protective Equipment, Central Institute for Labour Protection-National Research Institute, Wierzbowa 48, 90-133 Lodz, Poland.

A new set of underwear and protective clothing with phase change materials (PCM) for mine rescuers has been developed in order to increase their safety of work. It includes PCM pouches absorbing excess heat from the body. In order to evaluate thermal load of mine rescuers, physiological tests were carried out for three variants of possible use of the developed set of clothing: for mine rescuers wearing only the underwear with PCM; for a set of underwear and protective clothing; and for a complete set of clothing with closed-circuit compressed oxygen breathing apparatus. Read More

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September 2020

Effect of cooling strategies on overall performance of a hybrid personal cooling system incorporated with phase change materials (PCMs) and electric fans.

J Therm Biol 2020 Aug 14;92:102655. Epub 2020 Jul 14.

Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

The effect of four cooling strategies on cooling performance of a hybrid personal cooling system (HPCS) incorporated with phase change materials (PCMs) and electric fans in a hot environment (i.e., T = 36 ± 0. Read More

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Experimental study on the effectiveness of the PCM cooling vest in persons with paraplegia of varying levels.

J Therm Biol 2020 Jul 5;91:102634. Epub 2020 Jun 5.

Division of Neurosurgery, Department of Surgery, American University of Beirut Medical Center, P.O. Box: 11-0236, Riad El Solh Beirut, 1107 2020, Beirut, Lebanon.

Persons with paraplegia (PA) from thoracic spinal cord injury (T1-T12) are prone to thermal stress during exercise due to impaired thermoregulation. This study evaluates the effectiveness of phase change material (PCM) cooling vests on persons with PA of different levels of injury during exercise in hot exposure. Sixteen participants were recruited and divided to three groups based on injury level; high-thoracic T1-T3, mid-thoracic T4-T8, and low thoracic T9-T12 to perform a 30-min arm-crank exercise at a 30 °C room condition. Read More

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Compatibility of Phase Change Materials and Metals: Experimental Evaluation Based on the Corrosion Rate.

Molecules 2020 Jun 18;25(12). Epub 2020 Jun 18.

Brno University of Technology, Faculty of Civil Engineering, 602 00 Brno, Czech Republic.

The construction and maintenance of building stock is responsible for approximately 36% of all CO emissions in the European Union. One of the possibilities of how to achieve high energy-efficient and decarbonized building stock is the integration of renewable energy sources (RES) in building energy systems that contain efficient energy storage capacity. Phase Change Materials (PCMs) are latent heat storage media with a high potential of integration in building structures and technical systems. Read More

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Measurement of asbestos emissions associated with demolition of abandoned residential dwellings.

Sci Total Environ 2020 Jun 21;722:137891. Epub 2020 Mar 21.

University of Michigan, Department of Environmental Health Sciences, Ann Arbor, MI, USA.

Many cities are revitalizing their urban cores through the demolition of abandoned residential dwellings (ARDs). However, data regarding the emissions of asbestos during such an operation are sparse. We measured airborne asbestos emissions from emergency demolitions (demolitions on structures deemed too dangerous to enter and remove asbestos) of ARDs in Detroit. Read More

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Analysis of uncoated LPGs written in B-Ge doped fiber under proton irradiation for sensing applications at CERN.

Sci Rep 2020 Jan 28;10(1):1344. Epub 2020 Jan 28.

University of Sannio, Department of Engineering, Optoelectronics Group, I-82100, Benevento, Italy.

In this contribution, a complete dissertation concerning the behavior of a Long Period Grating (LPG) inscribed in a B-Ge co-doped optical fiber by means of an excimer laser and exposed to proton irradiation during a recent extensive campaign performed at the European Organization for Nuclear Research (CERN) with a fluence of 4.4·10 p∙cm is provided. The experimental results have been thus combined for the first time to the best of our knowledge with numerical simulations in order to estimate the variations of the major parameters affecting the grating response during the ultra-high dose proton exposure. Read More

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January 2020

Toward rational management of patent ductus arteriosus: ductal disease staging and first line paracetamol.

J Matern Fetal Neonatal Med 2019 Dec 29:1-6. Epub 2019 Dec 29.

Monash Newborn, Monash Children's Hospital, Clayton, Australia.

To study paracetamol (PCM) use as first line therapy for significant patent ductus arteriosus (sPDA) closure, stratified by echocardiography. In this retrospective observational study, a prepublished score comprising PDA size and velocity, PDA:left pulmonary artery ratio, diastolic flow in main and LPA, LA:Ao ratio and left ventricular:aortic ratio were included for shunt severity. Successful closure was defined as closure or ≥50% reduction in score. Read More

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December 2019