Coron Artery Dis 2021 May 18. Epub 2021 May 18.
The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai Clinical Trials Center, Cardiovascular Research Foundation Center for Interventional Vascular Therapy, Division of Cardiology, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, USA Division of Cardiology, University of California - San Diego, San Diego, California, USA Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada Erasmus Medical Center, Rotterdam, the Netherlands Department of Surgery, UH Cleveland Medical Center, Cleveland, Ohio, USA Department of Cardiology, National University of Ireland Galway (NUIG), Galway, Ireland Imperial College of London, London, UK.
Background: Prior studies have reported an association between elevated white blood cell count (WBCc) and worse clinical outcomes after coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). We assessed the prognostic impact of WBCc in patients undergoing revascularization for left main coronary artery disease (LMCAD).
Methods: In Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization (EXCEL), 1905 patients with LMCAD and low or intermediate SYNTAX scores were randomized to PCI with everolimus-eluting stents versus CABG. Read More