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Eating-related pathology at the intersection of gender identity and expression, sexual orientation, and weight status: An intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA) of the Growing Up Today Study cohorts.

Soc Sci Med 2021 May 31;281:114092. Epub 2021 May 31.

Department of Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA, 01655, USA. Electronic address:

The objective of this study was to investigate how gender identity, the overwhelmingly prioritized dimension of social identity/position in eating-related pathology research, intersects with gender expression, sexual orientation, and weight status to structure the social patterning of eating disorders and disordered eating behaviors among young people in the U.S. Data were drawn from the 2010/2011 Growing Up Today Study (GUTS; N = 11,090-13,307). Read More

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Effects of auditory feedback on gait behavior, gaze patterns and outcome performance in long jumping.

Hum Mov Sci 2021 Jun 9;78:102827. Epub 2021 Jun 9.

Department for the Psychology of Human Movement and Sport, Institute of Sport Science, Friedrich Schiller University Jena, Germany.

In the current study, we conducted two experiments to investigate the impact of concurrent, action-induced auditory feedback on gait patterns, gaze behavior and outcome performance in long jumping. In Experiment 1, we examined the effects of present vs. absent auditory feedback on gait, gaze and performance outcome measures. Read More

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Comparing Online and In-Store Grocery Purchases.

J Nutr Educ Behav 2021 Jun;53(6):471-479

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

Objective: To describe the grocery shopping patterns of people who shopped both online and in-store and evaluate whether shoppers purchased fewer unhealthy, impulse-sensitive items online.

Design: Secondary analysis of 44 weeks of grocery transaction data collected for fruit and vegetable incentive trials in 2 Maine supermarkets.

Participants: A total of 137 primary household shoppers who shopped at least once in-store and online (curbside pickup) for 5,573 total transactions MAIN OUTCOME MEASURES AND ANALYSIS: Paired t tests and descriptive analyses compared online and in-store transactions with respect to frequency, total spending, number of items purchased, and spending on 10 food groups and 34 subgroups. Read More

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Semicircular Lipoatrophy: A Case Series With Follow-up of 76 Patients in Madrid and a Proposed Classification.

Actas Dermosifiliogr 2021 Jun 8. Epub 2021 Jun 8.

Servicio de ITS/Dermatología. Sección de Especialidades Médicas, Organismo Autónomo Madrid Salud, Ayuntamiento de Madrid, Madrid, España. Electronic address:

Background And Objective: The clinical presentations of semicircular lipoatrophy (SL) vary, and diagnostic criteria are unclear. Several etiopathogenic factors, including occupational environmental ones, have been suggested. We aimed to describe a cluster of cases of suspected SL that started to appear in May 2008 among employees of the city council of Madrid, Spain. Read More

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Older Adult Patients Use More Aminosalicylate Monotherapy Compared With Younger Patients With Inflammatory Bowel Disease: TARGET-IBD.

J Clin Gastroenterol 2021 Jun 11. Epub 2021 Jun 11.

Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill Atrium Health Gastroenterology and Hepatology, Charlotte Target RWE, Health Evidence Solutions, Durham, NC Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, OH Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, WI Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai Division of Pediatric Gastroenterology, The Susan & Leonard Feinstein IBD Clinical Center at Icahn School of Medicine at Mount Sinai, New York, NY IBD Center, The University of Chicago Medicine, Chicago, IL Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

Goal: The goal of this study was to describe medication utilization patterns in older inflammatory bowel disease (IBD) patients.

Background: Despite a growing population of older patients with Crohn's disease (CD) and ulcerative colitis (UC), questions remain regarding medication utilization patterns in comparison to younger populations.

Materials And Methods: We collected data from the 34 sites in TARGET-IBD, a multicenter, observational cohort. Read More

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Identifying Patterns of Failure and Risk Factors for Recurrence in Patients of Paratesticular Sarcomas: Protocol of a Systematic Review and Meta-Analysis.

Int J Surg Protoc 2021 May 28;25(1):84-91. Epub 2021 May 28.

Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi, IN.

Introduction: Para testicular sarcomas are rare mesenchymal tumors that affect patients of all ages. Unlike other sites of sarcoma, they tend to be of lower grade and have a higher propensity for lymphatic spread. Management is hampered by the small number of patients who differ in terms of tumor grade and histology. Read More

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Prediction of outcome from MRI and general movements assessment after hypoxic-ischaemic encephalopathy in low-income and middle-income countries: data from a randomised controlled trial.

Arch Dis Child Fetal Neonatal Ed 2021 Jun 10. Epub 2021 Jun 10.

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Faculty of Medicine and Health Sciences, Trondheim, Norway.

Objective: To evaluate the accuracy of neonatal MRI and general movements assessment (GMA) in predicting neurodevelopmental outcomes in infants with hypoxic-ischaemic encephalopathy (HIE).

Design: Secondary analyses of a randomised controlled trial (RCT).

Setting: Tertiary neonatal intensive care unit in India. Read More

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Age-related Patterns of Vestibular Dysfunction in Dizziness and Imbalance: A Review of Vestibular Testing Results Among 1,116 Patients.

Otol Neurotol 2021 Jul;42(6):897-905

Department of Otolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania.

Objective: To characterize differences in vestibular testing results among patients presenting with balance-related complaints; to stratify patterns of testing abnormalities by age.

Study Design: Retrospective chart review.

Setting: Academic Balance Center at a Tertiary Referral Center. Read More

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Anatomical patterns of biliary atresia including hepatic radicles at the porta hepatis influence short- and long-term prognoses.

J Hepatobiliary Pancreat Sci 2021 Jun 10. Epub 2021 Jun 10.

Mashiko Memorial Hospital, Aichi Prefecture, 35-28 Takebashi-cho, Nakamura-ku, Nagoya, Japan, 4538566.

Background/purpose: The biliary atresia (BA) inflammatory process leads to various obstructive patterns of extrahepatic biliary trees. The significance of the various BA obstructive patterns is unclear. This study aimed to determine the relationship between the anatomical patterns of the biliary tract and short- and long-term prognoses in BA. Read More

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Interaction between thrombin potential and age on early clinical outcome in patients hospitalized for COVID-19.

J Thromb Thrombolysis 2021 Jun 10. Epub 2021 Jun 10.

Dipartimento Di Medicina Traslazionale, Università del Piemonte Orientale, Azienda Ospedaliero-Universitaria Maggiore Della Carità, Via Solaroli 17, 28100, Novara, NO, Italy.

Patients with Coronavirus Disease-2019 (COVID-19) have haemostatic dysfunction and are at higher risk of thrombotic complications. Although age is a major risk factor for outcome impairment in COVID-19, its impact on coagulative patterns here is still unclear. We investigated the association of Endogenous Thrombin Potential (ETP) with thrombotic and haemorrhagic events according to different ages in patients admitted for COVID-19. Read More

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Beyond Microsatellite Instability: Evolving Strategies Integrating Immunotherapy for Microsatellite Stable Colorectal Cancer.

Curr Treat Options Oncol 2021 Jun 10;22(8):69. Epub 2021 Jun 10.

Clinical Oncology, Università Politecnica delle Marche, AOU Ospedali Riuniti, Via Conca 71, 60126, Ancona, Italy.

Opinion Statement: Advanced colorectal cancer (CRC) is a heterogeneous disease, characterized by several subtypes with distinctive genetic and epigenetic patterns. During the last years, immune checkpoint inhibitors (ICIs) have revamped the standard of care of several tumors such as non-small cell lung cancer and melanoma, highlighting the role of immune cells in tumor microenvironment (TME) and their impact on cancer progression and treatment efficacy. An "immunoscore," based on the percentage of two lymphocyte populations both at tumor core and invasive margin, has been shown to improve prediction of treatment outcome when added to UICC-TNM classification. Read More

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Microperimetry Hill of Vision and Volumetric Measures of Retinal Sensitivity.

Transl Vis Sci Technol 2021 Jun;10(7):12

Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford Biomedical Research Centre, Oxford, UK.

Purpose: Mean retinal sensitivity is the main output measure used in microperimetry. It is, however, of limited use in patients with poor vision because averaging is weighted toward zero in those with significant scotomas creating an artificial floor effect. In contrast, volumetric measures avoid these issues and are displayed graphically as a hill of vision. Read More

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Quantitative dynamic near-infrared fluorescence imaging using indocyanine green for analysis of bowel perfusion after mesenteric resection.

J Biomed Opt 2021 Jun;26(6)

Leiden University Medical Center, Department of Surgery, Leiden, The Netherlands.

Significance: Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has proven to be a feasible application for real-time intraoperative assessment of tissue perfusion, although quantification of NIR fluorescence signals is pivotal for standardized assessment of tissue perfusion.

Aim: Four patients are described with possible compromised bowel perfusion after mesenteric resection. Based on these patients we want to emphasize the difficulties in the quantification of NIR fluorescence imaging for perfusion analysis. Read More

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Intersectional (in) equities in contact coverage of maternal and newborn health services in Nepal: insights from a nationwide cross-sectional household survey.

BMC Public Health 2021 Jun 9;21(1):1098. Epub 2021 Jun 9.

School of Public Health, Faculty of Medicine, University of Queensland, Brisbane, Australia.

Background: Persistent inequities in coverage of maternal and newborn health (MNH) services continue to pose a major challenge to the health-care system in Nepal. This paper uses a novel composite indicator of intersectional (dis) advantages to examine how different (in) equity markers intersect to create (in) equities in contact coverage of MNH services across the continuum of care (CoC) in Nepal.

Methods: A secondary analysis was conducted among 1978 women aged 15-49 years who had a live birth in the two years preceding the survey. Read More

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Disparities in Telemedicine Access: A Cross-Sectional Study of a Newly Established Infrastructure during the COVID-19 Pandemic.

Appl Clin Inform 2021 05 9;12(3):445-458. Epub 2021 Jun 9.

University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin, United States.

Background: The COVID-19 pandemic led to dramatic increases in telemedicine use to provide outpatient care without in-person contact risks. Telemedicine increases options for health care access, but a "digital divide" of disparate access may prevent certain populations from realizing the benefits of telemedicine.

Objectives: The study aimed to understand telemedicine utilization patterns after a widespread deployment to identify potential disparities exacerbated by expanded telemedicine usage. Read More

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Treatment of Monteggia-like-lesion in a young patient: A case report.

Medicine (Baltimore) 2021 May;100(19):e24928

Orthopaedic and Traumatology Department, Faculty of Medicine Universitas Brawijaya, Saiful Anwar General Hospital, Malang, Indonesia.

Introduction: A Monteggia fracture was described initially as a fracture of the proximal third ulna and anterior dislocation of the proximal epiphysis radius.[1] In 1967, Bado discovered "true Monteggia lesions" and classified them into 4 groups.[2] He also used the term "equivalents" or "Monteggia-like-lesions" to describe specific injuries with similar radiographic patterns. Read More

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How the coronavirus disease 2019 pandemic changed the patterns of healthcare utilization by geriatric patients and the crowding: a call to action for effective solutions to the access block.

Intern Emerg Med 2021 Jun 9. Epub 2021 Jun 9.

Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

The geriatric population constitutes a large slice of the population of Western countries and a class of fragile patients, with greater deaths due to COVID-19. The patterns of healthcare utilization change during pandemic disease outbreaks. Identifying the patterns of changes of this particular fragile subpopulation is important for future preparedness and response. Read More

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mHealth Interventions for Treatment Adherence and Outcomes of Care for Cardiometabolic Disease Among Adults Living With HIV: Systematic Review.

JMIR Mhealth Uhealth 2021 Jun 9;9(6):e20330. Epub 2021 Jun 9.

Non-Communicable Disease Research Unit, Medical Research Council, Cape Town, South Africa.

Background: The success of antiretroviral therapy has led to an increase in life expectancy and an associated rise in the risk of cardiometabolic diseases (CMDs) among people living with HIV.

Objective: Our aim was to conduct a systematic review to synthesize the existing literature on the patterns of use and effects of mobile health (mHealth) interventions for improving treatment adherence and outcomes of care for CMD among people living with HIV.

Methods: A systematic search of multiple databases, including PubMed-MEDLINE, Embase, CINAHL, Scopus, Web of Science, African Journals online, ClinicalTrials. Read More

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Treatment and outcome patterns of patients with Waldenström's macroglobulinemia: a large, multicenter retrospective review in China.

Leuk Lymphoma 2021 Jun 9:1-8. Epub 2021 Jun 9.

Department of Hematology, Hubei, China.

In this study, we aimed to investigate treatment options and the prognosis of patients with WM in China. This retrospective study included 1141 patients diagnosed with symptomatic WM between January 2003 and December 2019 at 35 tertiary hospitals in 22 provinces of China. Fifty-four patients (7. Read More

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Examination of refractory discoid lateral meniscus injury.

J Orthop Surg (Hong Kong) 2021 May-Aug;29(2):23094990211022043

Department of Orthopedic Surgery, Fujigaoka Hospital, Showa University, Yokohama, Kanagawa, Japan.

Background: Lateral discoid meniscus (LDM) should be treated and preserved with saucerization and/or suture repair. However, repair of the meniscal hoop structure is sometimes difficult due to displacement or large defects. In this study, we aimed to examine tear patterns based on the Ahn classification in those requiring meniscal repair and those undergoing subtotal meniscectomy. Read More

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Improving the engagement of Aboriginal families with maternal and child health services: a new model of care.

Public Health Res Pract 2021 Jun 9;31(2). Epub 2021 Jun 9.

Melbourne School of Population and Global Health, University of Melbourne, VIC, Australia.

Objectives: Access in the early years to integrated community-based services that are flexible in their approach, holistic and culturally strong is a proven critical predictor of a child's successful transition to school and lifelong education and employment outcomes, providing long-term wellbeing. Studies show that participation in maternal and child health (MCH) services in Victoria, Australia, improve health outcomes for children and families, particularly for Aboriginal families. Poorer health outcomes and lower participation rates for these families in MCH services suggest there is a need for an urgent review of the current service model. Read More

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Otolaryngologists Practice Pattern on Oral Allergy Syndrome.

Allergy Rhinol (Providence) 2021 Jan-Dec;12:21526567211021305. Epub 2021 May 28.

Department of Otolaryngology & Communication, SUNY Upstate Medical University, Syracuse, New York.

Background: Oral allergy syndrome is a unique type of food allergy caused by cross-sensitivity between inhalant allergens and food allergens. Despite its significant prevalence and potentially serious outcome, the knowledge base and practice patterns on OAS are not well known among otolaryngologists. Our study is designed to understand the practice patterns of otolaryngologists in screening, testing, and treating OAS through a web-based survey. Read More

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Patterns and Outcomes of dog bite injuries presenting to emergency department in a tertiary care hospital at Karachi.

Pak J Med Sci 2021 May-Jun;37(3):794-799

Dr. Nasibullah Ahmed Lecturer, Department of Forensic Medicine, Ziauddin University, Karachi, Pakistan.

Objectives: To assess patterns & outcomes of dog bite injuries coming to a public sector tertiary care hospital in Karachi, Pakistan.

Methods: This was a one-year descriptive cross sectional study from 1 June 2018- 31 May 2019 using consecutive sampling technique. Data of 7512 patients was collected from animal-bite clinic of a tertiary care hospital. Read More

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Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).

Int J Chron Obstruct Pulmon Dis 2021 31;16:1477-1496. Epub 2021 May 31.

Department of Mechanical Engineering, University of Iowa, Iowa City, IA, USA.

Purpose: Quantitative computed tomography (qCT) imaging-based cluster analysis identified clinically meaningful COPD former-smoker subgroups (clusters) based on cross-sectional data. We aimed to identify progression clusters for former smokers using longitudinal data.

Patients And Methods: We selected 472 former smokers from SPIROMICS with a baseline visit and a one-year follow-up visit. Read More

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Cooperation patterns of members in networks during co-creation.

Sci Rep 2021 Jun 8;11(1):11588. Epub 2021 Jun 8.

Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, 153-8902, Japan.

Cooperation (i.e., co-creation) has become the principal way of carrying out creative activities in modern society. Read More

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Mortality Trends from Urologic Cancers in Europe over the Period 1980-2017 and a Projection to 2025.

Eur Urol Oncol 2021 Jun 5. Epub 2021 Jun 5.

Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy; Department of Humanities, Pegaso Online University, Naples, Italy.

Background: Patterns and trends in urologic cancer mortality still show geographical differences across Europe.

Objective: To monitor mortality trends from urologic cancers, including prostate, testis, bladder, and kidney cancers, in Europe.

Design, Setting, And Participants: We carried out a time-trend analysis for 36 European countries using the official World Health Organization database. Read More

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A new integrated behavioural intervention for knee osteoarthritis: development and pilot study.

BMC Musculoskelet Disord 2021 Jun 8;22(1):526. Epub 2021 Jun 8.

Faculty of Health and Applied Sciences, University of the West of England, Bristol, BS16 1DD, UK.

Background: Exercise-based approaches have been a cornerstone of physiotherapy management of knee osteoarthritis for many years. However, clinical effects are considered small to modest and the need for continued adherence identified as a barrier to clinical efficacy. While exercise-based approaches focus on muscle strengthening, biomechanical research has identified that people with knee osteoarthritis over activate their muscles during functional tasks. Read More

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Does Severity of Brain Injury on Magnetic Resonance Imaging Predict Short-Term Outcome in Neonates Who Received Therapeutic Hypothermia?

Am J Perinatol 2021 Jun 8. Epub 2021 Jun 8.

Neonatal-Perinatal Medicine, Children's Hospital of Michigan, Detroit, Michigan.

Objective:  The National Institute of Child Health and Human Development (NICHD) magnetic resonance imaging (MRI) pattern of brain injury is a known biomarker of childhood outcome following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (HIE). However, usefulness of this classification has not been evaluated to predict short-term outcomes. The study aimed to test the hypothesis that infants with NICHD MRI pattern of severe hypoxic-ischemic brain injury will be sicker with more severe asphyxia-induced multiorgan dysfunction resulting in prolonged length of stay (LOS) following therapeutic hypothermia. Read More

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The Impact of Sex Chromosome Trisomies (XXX, XXY, XYY) on Early Social Cognition: Social Orienting, Joint Attention, and Theory of Mind.

Arch Clin Neuropsychol 2021 Jun 9. Epub 2021 Jun 9.

Department of Clinical Neurodevelopmental Sciences, Leiden University, Leiden, The Netherlands.

Objective: About 1:650-1,000 children are born with an extra X or Y chromosome (XXX; XXY; XYY), which results in a sex chromosome trisomy (SCT). This study aims to cross-sectionally investigate the impact of SCT on early social cognitive skills. Basic orienting toward social cues, joint attention, and theory of mind (ToM) in young children with SCT were evaluated. Read More

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What Are the Functional Outcomes and Pain Scores after Medial Clavicle Fracture Treatment?

Clin Orthop Relat Res 2021 06 8. Epub 2021 Jun 8.

D. Zhang, B. Earp, Hand and Upper Extremity Surgery, Brigham and Women's Hospital, Boston, MA, USA.

Background: Medial clavicle fractures are uncommon, occurring in older and multiply injured patients. The management of these fractures and the factors that predispose toward poor outcomes are controversial. Furthermore, the functional outcomes of treatment are not well characterized or correlated with fracture patterns. Read More

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