201,027 results match your criteria patients stroke


Hemicraniectomy for Dominant vs Nondominant Middle Cerebral Artery Infarction: A Systematic Review and Meta-Analysis.

J Stroke Cerebrovasc Dis 2021 Sep 15;30(11):106102. Epub 2021 Sep 15.

Department of Neurology, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, Helsinki 00290, Finland.

Objectives: Decompressive hemicraniectomy decreases mortality and severe disability from space-occupying middle cerebral artery infarction in selected patients. However, attitudes towards hemicraniectomy for dominant-hemispheric stroke have been hesitant. This systematic review and meta-analysis examines the association of stroke laterality with outcome after hemicraniectomy. Read More

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September 2021

Predictors of Infarction in Tuberculous Meningitis in Indian Patients.

J Stroke Cerebrovasc Dis 2021 Sep 15;30(11):106088. Epub 2021 Sep 15.

Department OF Neurology, AIIMS, New Delhi. Electronic address:

Background: Stroke is a devastating complication of tuberculous meningitis (TBM) and is an important determinant of its outcome. We propose a model which would help to predict development of infarction or cerebrovascular events in patients of TBM.

Methods: A prospective study with n=129 patients of TBM were evaluated for predictors and outcomes of stroke. Read More

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September 2021

Perioperative goal-directed therapy in high-risk abdominal surgery. A multicenter randomized controlled superiority trial.

J Clin Anesth 2021 Sep 15;75:110506. Epub 2021 Sep 15.

Department of Anesthesiology, Maastricht University Medical Center, Maastricht, the Netherlands. Electronic address:

Study Objective: The potential of perioperative goal-directed therapy (PGDT) to improve outcome after high-risk abdominal surgery remains subject of debate. In particular, there is a need for large, multicenter trials focusing on relevant patient outcomes to confirm the evidence found in small, single center studies including minor complications in their composite endpoints. The present study therefore aims to investigate the effect of an arterial waveform analysis based PGDT algorithm on the incidence of major complications including mortality after high-risk abdominal surgery. Read More

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September 2021

The assessment of cognitive functions in patients with isolated cerebellar infarctions: A follow-up study.

Neurosci Lett 2021 Sep 15:136252. Epub 2021 Sep 15.

Health Sciences University, Istanbul Training and Research Hospital, Department of Neurology, Istanbul, Turkey.

The role of the cerebellum on cognitive functions have been well-defined; however, the information related to the progress in time process is limited. In this study, we aimed to evaluate the cognitive function of patients with isolated cerebellar infarction in both the acute stage and the follow-up period. Twenty-three patients with isolated cerebellar infarction and 22 healthy control were examined through an extensive neuropsychological assessment battery. Read More

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September 2021

An Echocardiography-derived Calcium Score as a Predictor of Major Adverse Cardiovascular Events in Peritoneal Dialysis Patients - A Prospective Cohort Study.

Nephrology (Carlton) 2021 Sep 18. Epub 2021 Sep 18.

Kwong Wah Hospital, Hong Kong.

Background: An echocardiography-derived calcium score (ECS) has been shown to predict CV mortality in the general population but has not been utilized in the dialysis population.

Methods: We conducted a prospective cohort study including 125 prevalent PD patients. Two blinded and independent echocardiographers determined the ECS for each subject at baseline. Read More

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September 2021

Relation of Pre-stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes.

Ann Neurol 2021 Sep 18. Epub 2021 Sep 18.

Department of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea.

Objective: We investigated a) the associations between pre-stroke aspirin use and thrombus burden, infarct volume, hemorrhagic transformation, early neurological deterioration (END), and functional outcome, and b) whether stroke subtypes modify these associations in first-ever ischemic stroke.

Methods: This multicenter MRI-based study included 5,700 consecutive patients with acute first-ever ischemic stroke, who did not undergo intravenous thrombolysis or endovascular thrombectomy, from May-2011 through February-2014. Propensity score-based augmented inverse probability weighting was performed to estimate adjusted effects of pre-stroke aspirin use. Read More

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September 2021

The efficacy and safety of novel classes of glucose-lowering drugs for cardiovascular outcomes: a network meta-analysis of randomised clinical trials.

Diabetologia 2021 Sep 18. Epub 2021 Sep 18.

Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Aims/hypothesis: Several cardiovascular outcome trials on sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been released recently, including trials enrolling patients with congestive heart failure (CHF) and chronic kidney disease (CKD). Comparisons of the efficacy and safety of SGLT2i, glucagon-like peptide-1 receptor agonists (GLP-1RA) and dipeptidyl peptidase-4 inhibitors (DPP-4i) thus require an update. Assessments in patient subgroups, i. Read More

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September 2021

A comparison of the Stress Hyperglycemia Ratio, Glycemic Gap, and glucose to assess the impact of stress-induced hyperglycemia on ischemic stroke outcome.

J Diabetes 2021 Sep 18. Epub 2021 Sep 18.

Diabetes and Endocrine Services, Flinders Medical Centre, Bedford Park, Australia.

Aim: To compare metrics specific for stress-induced hyperglycemia (SIH) with glucose for predicting ischemic stroke outcome.

Methods: This observational retrospective study (n = 300) included patients acutely hospitalized for ischemic stroke over a 3.8-year period. Read More

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September 2021

Low incidence of major complications after the first six hours post atrial fibrillation ablation: Is same-day discharge safe and feasible in most patients?

J Cardiovasc Electrophysiol 2021 Sep 17. Epub 2021 Sep 17.

Department of Cardiology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

Aims: This study evaluates the incidence of procedural complications related to catheter ablation of atrial fibrillation (AF) to assess the potential feasibility and safety of same-day discharge in a large cohort.

Methods: We performed an analysis of prospectively collected data of complications of all patients staying overnight after undergoing AF ablation between 2001 and 2020 at a tertiary centre. Using medical records, we analysed complications occurring intraprocedurally until six hours post-ablation and between six hours post-ablation and discharge the day after ablation procedure. Read More

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September 2021

Single-Sweep Pulmonary Vein Isolation using the new third-generation laser balloon - Evolution in ablation style using endoscopic ablation system.

J Cardiovasc Electrophysiol 2021 Sep 17. Epub 2021 Sep 17.

Cardioangiologisches Centrum Bethanien, Frankfurt, Germany.

Background: The endoscopic ablation system (EAS) is an established ablation device for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). The novel X3 EAS is now equipped with a contiguous circumferential ablation mode (RAPID mode).

Aim: To determine the feasibility of single-shot fashioned ablation using X3. Read More

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September 2021

Angiotensin converting enzyme inhibitors and incidence of lung cancer in a population based cohort of common data model in Korea.

Sci Rep 2021 Sep 17;11(1):18576. Epub 2021 Sep 17.

Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.

Contradictory findings exist about association of angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blocker (ARB) with lung cancer development. This was a retrospective observational cohort study that used data from 7 hospitals in Korea, converted to the Observational Medical Outcomes Partnership Common Data Model. The primary outcome was occurrence of lung cancer. Read More

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September 2021

Lesion site and therapy time predict responses to a therapy for anomia after stroke: a prognostic model development study.

Sci Rep 2021 Sep 17;11(1):18572. Epub 2021 Sep 17.

Institute of Cognitive Neuroscience, University College London, 17-19 Queen Square, London, WC1N 3AR, UK.

Stroke is a leading cause of disability, and language impairments (aphasia) after stroke are both common and particularly feared. Most stroke survivors with aphasia exhibit anomia (difficulties with naming common objects), but while many therapeutic interventions for anomia have been proposed, treatment effects are typically much larger in some patients than others. Here, we asked whether that variation might be more systematic, and even predictable, than previously thought. Read More

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September 2021

Spontaneous Spinal Epidural Hematoma Mimicking Stroke and Its Outcome post Intravenous Thrombolysis.

Cerebrovasc Dis 2021 Sep 15:1-5. Epub 2021 Sep 15.

Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong, China.

Background And Purpose: Spontaneous spinal epidural hematoma (SSEH) is a rare neurological emergency. Its presentation, depending on location of hematoma, could mimic stroke. While intravenous thrombolysis (IVT) is recommended to commence as early as possible in case of acute ischemic stroke, it is likely that it could be given to SSEH patients. Read More

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September 2021

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study.

BMJ 2021 09 17;374:n2244. Epub 2021 Sep 17.

Division of Primary Care, School of Medicine, University of Nottingham, Nottingham, UK.

Objectives: To derive and validate risk prediction algorithms to estimate the risk of covid-19 related mortality and hospital admission in UK adults after one or two doses of covid-19 vaccination.

Design: Prospective, population based cohort study using the QResearch database linked to data on covid-19 vaccination, SARS-CoV-2 results, hospital admissions, systemic anticancer treatment, radiotherapy, and the national death and cancer registries.

Settings: Adults aged 19-100 years with one or two doses of covid-19 vaccination between 8 December 2020 and 15 June 2021. Read More

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September 2021

Comparative efficacy of non-invasive neurostimulation therapies for poststroke dysphagia: A systematic review and meta-analysis.

Neurophysiol Clin 2021 Sep 15. Epub 2021 Sep 15.

Department of Physical Medicine and Rehabilitation, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, 266000, PR China. Electronic address:

Objective: To explore the effect of non-invasive neurostimulation therapies on dysphagia patients after stroke.

Methods: We searched MEDLINE (Ovid), PubMed, Embase, Web of Science, ScienceDirect, and Cochrane library databases until April 22, 2020. All published and unpublished randomized controlled trials (RCT) were included. Read More

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September 2021

Application of Ultrasonography in the Diagnosis of Rhabdomyolysis.

Ultrasound Med Biol 2021 Sep 14. Epub 2021 Sep 14.

Department of Ultrasonography, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address:

Early diagnosis and treatment of rhabdomyolysis are very important, but difficult to achieve for some atypical cases. Our study was aimed at determining the diagnostic value of ultrasonography in rhabdomyolysis caused by different factors. The study enrolled 50 patients with rhabdomyolysis diagnosed in our hospital. Read More

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September 2021

Safety Matters: A Meta-analysis of Interhospital Transport Adverse Events in Critically Ill Patients.

Air Med J 2021 Sep-Oct;40(5):350-358. Epub 2021 May 24.

Research Associate Program, Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD; Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD; Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD. Electronic address:

Objective: Interhospital transport (IHT) is common among critically ill patients. Our meta-analysis investigated the prevalence and possible factors associated with adverse events (AEs) during IHT.

Methods: Searching PubMed, Embase, and Scopus databases until February 12, 2021, we included studies that a priori defined AEs for adult medical patients. Read More

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Impact of Helicopter Transport on Reperfusion Times and Long-Term Outcomes in Acute Myocardial Infarction Patients in Rural Areas: A Report From the Mie Acute Coronary Syndrome Registry.

Air Med J 2021 Sep-Oct;40(5):337-343. Epub 2021 May 30.

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.

Objective: Helicopter emergency medical services (HEMS) are effective for time-sensitive conditions, such as stroke and trauma. However, prognostic data on helicopter transport for acute myocardial infarction (AMI) patients are insufficient.

Methods: We registered 2,681 AMI patients in the Mie Acute Coronary Syndrome Registry and enrolled 163 patients from rural areas to HEMS base hospitals with HEMS or ground emergency medical services (GEMS). Read More

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Economic burden of comorbid chronic conditions among survivors of stroke in China: 10-year longitudinal study.

BMC Health Serv Res 2021 Sep 17;21(1):978. Epub 2021 Sep 17.

Department of Global Health, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China.

Background: The coexistence of chronic diseases among people with stroke is common. However, little is known about the extent of incremental healthcare expenditures associated with having physically and psychologically chronic conditions among stroke survivors.

Methods: We used the nationally representative data from the China Health and Nutrition Survey, including 36,076 participants enrolled as our analytic cohort of ten years of follow-up visits (2006, 2009, 2011, 2015). Read More

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September 2021

Acute ischemic stroke with cervical internal carotid artery steno-occlusive lesion: multicenter analysis of endovascular approaches.

BMC Neurol 2021 Sep 17;21(1):362. Epub 2021 Sep 17.

UOC Neurologia e Rete Stroke metropolitana Ospedale Maggiore CA Pizzardi - IRCCS delle scienze Neurologiche di Bologna, Bologna, Italy.

Background: Occlusion of the internal carotid artery (ICA), whether isolated or in the setting of a tandem lesion (TL) have a poor response to treatment with intravenous thrombolysis. Previous studies ​​have demonstrated the superiority of mechanical thrombectomy in the treatment of acute ischemic stroke (AIS) following large vessel occlusion, compared to standard intravenous fibrinolysis. The aim of our study was to describe endovascular treatment (EVT) in AIS due to isolated ICA occlusion or TL. Read More

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September 2021

Delayed headache after COVID-19 vaccination: a red flag for vaccine induced cerebral venous thrombosis.

J Headache Pain 2021 Sep 17;22(1):108. Epub 2021 Sep 17.

Department of Neurology, Akershus University Hospital, Lørenskog, Norway.

Background: Headache is a frequent symptom following COVID-19 immunization with a typical onset within days post-vaccination. Cases of cerebral venous thrombosis (CVT) have been reported in adenovirus vector-based COVID-19 vaccine recipients.

Findings: We reviewed all vaccine related CVT published cases by April 30, 2021. Read More

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September 2021

Extended Anticoagulant Treatment with Full- or Reduced-Dose Apixaban in Patients with Cancer-Associated Venous Thromboembolism: the API-CAT Study.

Thromb Haemost 2021 Sep 17. Epub 2021 Sep 17.

Unité de Recherche Clinique Innovation et Pharmacologie, Centre Hospitalier Universitaire de Saint-Etienne, Saint-Etienne, France.

Cancer-associated thrombosis (CAT) is associated with a high risk of recurrent venous thromboembolic events (VTE) that require extended anticoagulation in patients with active cancer, putting them at risk of bleeding.The aim of the API-CAT study (NCT03692065) is to assess whether a reduced-dose regimen of apixaban (2.5 mg twice daily [bid]) is non-inferior to a full-dose regimen of apixaban (5 mg bid) for the prevention of recurrent VTE in patients with active cancer who have completed ≥6 months of anticoagulant therapy for a documented index event of proximal deep-vein thrombosis and/or pulmonary embolism. Read More

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September 2021

The level of urbanization influences acute ischemic stroke care: A nationwide ecological study from Germany.

J Neurol Sci 2021 Sep 13;430:119983. Epub 2021 Sep 13.

Department of Neurology, St. Josef-Hospital Bochum, Ruhr University Bochum, Germany; Medical Faculty, Ruhr University Bochum, Germany. Electronic address:

Background And Purpose: Regional differences in acute ischemic stroke (AIS) care are still reported for Germany but not fully understood. We aimed to analyze the impact of the level of urbanization on the application of proved treatment procedures and the incidence of hospitalized AIS cases in Germany.

Methods: The level of urbanization of the 401 districts and district-free cities in Germany was defined according to the Federal Institute for Building, Urban Affairs and Spatial Research classification. Read More

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September 2021

Endovascular Transcarotid Artery Revascularization Using the Walrus Balloon Guide Catheter: Preliminary Experience.

World Neurosurg 2021 Sep 14. Epub 2021 Sep 14.

Department of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA. Electronic address:

Background: The Walrus Balloon Guided System Catheter (QApel Medical Inc, Fremont, CA) is a new generation of BGC, designed to bypass some technical limitations of conventional BGC devices. Their utility in cervical carotid disease treatment has not been reported. We report our preliminary experience in cervical carotid treatment using the Walrus BGC to perform a modified endovascular transcarotid artery revascularization (TCAR) technique. Read More

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September 2021

Plasma and genetic determinants of soluble TREM-1 and major adverse cardiovascular events in a prospective cohort of acute myocardial infarction patients. Results from the FAST-MI 2010 study.

Int J Cardiol 2021 Sep 15. Epub 2021 Sep 15.

Sorbonne Université, Université Pierre et Marie Curie site St Antoine, F-75012 Paris, France; FACT (French Alliance for CV clinical Trials), F-CRIN Network, Inserm U-1148, Paris, France; Hôpitaux de Paris, Clinical Pharmacology Department, Plateforme de Recherche Clinique de L'Est Parisien (URCEST-CRCEST-CRBHUEP-SU), Hôpital Saint Antoine, Paris, France.

Introduction: Triggering receptor expressing on myeloid cells (TREM)-1 is involved in the pathophysiology of ischemic heart disease. Plasma soluble TREM-1 levels (sTREM-1) has been associated with increased risk of major adverse cardiovascular events (MACE) in acute myocardial infarction (AMI) patients. However, the causative link between TREM-1 and MACE remains unknown and requires further investigation before developing potential therapeutic approaches. Read More

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September 2021

Efficacy of a family-based cardiovascular risk reduction intervention in individuals with a family history of premature coronary heart disease in India (PROLIFIC): an open-label, single-centre, cluster randomised controlled trial.

Lancet Glob Health 2021 Oct;9(10):e1442-e1450

Public Health Foundation of India, New Delhi, India; Centre for Chronic Disease Control, New Delhi, India; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

Background: Coronary heart disease, a leading cause of death globally, is amenable to lifestyle interventions. The family environment can affect the ability or willingness of individuals to make lifestyle changes. We aimed to investigate the efficacy of a targeted family-based intervention for reduction of total cardiovascular risk in individuals with a family history of premature coronary heart disease. Read More

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October 2021

Estimating the cost and value of functional changes in communication ability following telepractice treatment for aphasia.

PLoS One 2021 17;16(9):e0257462. Epub 2021 Sep 17.

Department of Speech, Language and Hearing Sciences, University of Florida, Gainesville, Florida, United States of America.

Context: Aphasia is a post-stroke condition that can dramatically impact a person with aphasia's (PWA) communication abilities. To date, few if any studies have considered the cost and cost-effectiveness of functional change in aphasia nor considered measures of patient's value for aphasia treatment.

Objective: To assess the cost, cost-effectiveness, and perceived value associated with improved functional communication in individuals receiving telerehabilitation treatment for aphasia. Read More

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September 2021

Ipsilateral internal carotid artery web and acute ischemic stroke: A cohort study, systematic review and meta-analysis.

PLoS One 2021 17;16(9):e0257697. Epub 2021 Sep 17.

Division of Vascular Neurology, Department of Neurology, Vidant Medical Center, Greenville, North Carolina, United States of America.

Introduction: The carotid web is a compelling potential mechanism of embolic ischemic stroke. In this study, we aim to determine the prevalence of ipsilateral carotid web in a cohort of ischemic stroke patients and to perform a systematic review and meta-analysis of similar cohorts.

Patients & Methods: We performed a retrospective, observational, cohort study of acute ischemic stroke patients admitted to a comprehensive stroke center from June 2012 to September 2017. Read More

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September 2021

Racial Disparities in Stroke Readmissions Reduced in Hospitals with Better Nurse Staffing.

Nurs Res 2021 Sep 15. Epub 2021 Sep 15.

University of Pennsylvania School of Nursing, Philadelphia, PA University of Villanova College of Nursing, Villanova, PA Department of Anesthesiology and Critical Care Medicine, Division of Critical Care, Children's Hospital of Philadelphia, Philadelphia, PA Hospital of the University of Pennsylvania, Department of Internal Medicine, Philadelphia, PA.

Background: Racial minorities are disproportionately affected by stroke, with Black patients experiencing worse post-stroke outcomes than White patients. A modifiable aspect of acute stroke care delivery not yet examined is whether disparities in stroke outcomes are related to hospital nurse staffing levels.

Objectives: To determine whether 7- and 30-day readmission disparities between Black and White patients were associated with nurse staffing levels. Read More

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September 2021

Redo-transcatheter aortic valve replacement with the supra-annular, self-expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry.

Catheter Cardiovasc Interv 2021 Sep 17. Epub 2021 Sep 17.

Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Objectives: To assess the safety profile of redo-TAVR procedures from patients in the transcatheter valve therapy (TVT) Registry.

Background: The use of transcatheter aortic valves (TAV) to treat previously implanted failing TAVS (TAV-in-TAV) has been an increasingly important topic as indications for TAVR move to younger and lower-risk patients, but data on the safety and efficacy of redo-TAVR is limited.

Methods: Patients undergoing redo-TAVR procedures using the Evolut R, Evolut PRO or Evolut PRO+ valve in the TVT Registry between April 2015 and March 2020 were included. Read More

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September 2021