266,108 results match your criteria patients selected


Multifragmentary proximal humerus fracture successfully treated with k-wire fixation: A case report.

Int J Surg Case Rep 2021 Sep 15;87:106415. Epub 2021 Sep 15.

Department of Orthopaedics and Trauma, National Hospital of Sri Lanka, Colombo, Sri Lanka.

Introduction And Importance: The ideal treatment of proximal humerus fracture remains a controversial topic, especially in the case of complex multi-fragmentary fractures. However, in limited resource settings, alternative less complicated fixation may be considered in highly selected patients without compromising the functional outcome. We report a case of successful treatment with k-wire fixation with satisfactory functional outcome. Read More

View Article and Full-Text PDF
September 2021

Changes in the epidemiology of patients hospitalized in France with deep venous thrombosis and pulmonary embolism during the COVID-19 pandemic.

Thromb Res 2021 Sep 21;207:67-74. Epub 2021 Sep 21.

Santé Publique France, Saint-Maurice 94, France.

Introduction: The onset of the COVID-19 pandemic and the first national lockdown implemented might have disrupted the epidemiology of deep venous thrombosis (DVT) and pulmonary embolism (PE). This study aimed to analyze time trends in patients hospitalized for DVT and PE in France and related in-patient and 90-day post-admission mortality rates.

Materials And Methods: All patients hospitalized in France for DVT or PE between January and September (weeks 1-40) for each year from 2017 to 2020, were selected. Read More

View Article and Full-Text PDF
September 2021

The role of simultaneous medical conditions in Idiopathic Normal Pressure Hydrocephalus.

World Neurosurg 2021 Sep 22. Epub 2021 Sep 22.

UOC Neurochirurgia, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.

Background: Idiopathic normal pressure hydrocephalus (iNPH) is a chronic neurological syndrome that affects the elderly population in a context of concomitant medical conditions. The aim of this study was to understand the significance of comorbidities using four validated and specific clinical scores: CIRS (Cumulative Illness Rating Scale), American Society of Anesthesiologists (ASA) Score, Co-morbidity Index (CCI) and Charlson Comorbidity Index and (CMI).

Methods: From 2015 until 2019, the Bologna PRO-Hydro multidisciplinary team selected 63 patients for shunt surgery. Read More

View Article and Full-Text PDF
September 2021

Fast generation of lung SBRT plans with a knowledge-based planning model on ring-mounted Halcyon Linac.

J Appl Clin Med Phys 2021 Sep 25. Epub 2021 Sep 25.

Medical Physics Graduate Program, Department of Radiation Medicine, University of Kentucky, Lexington, Kentucky, USA.

Purpose: To demonstrate fast treatment planning feasibility of stereotactic body radiation therapy (SBRT) for centrally located lung tumors on Halcyon Linac via a previously validated knowledge-based planning (KBP) model to support offline adaptive radiotherapy.

Materials/methods: Twenty previously treated non-coplanar volumetric-modulated arc therapy (VMAT) lung SBRT plans (c-Truebeam) on SBRT-dedicated C-arm Truebeam Linac were selected. Patients received 50 Gy in five fractions. Read More

View Article and Full-Text PDF
September 2021

Aortic valve replacement in a patient with self-reported systemic multiple metal allergy.

Gen Thorac Cardiovasc Surg 2021 Sep 25. Epub 2021 Sep 25.

First Department of Surgery, University of Toyama, Toyama, Japan.

We report our experience with aortic valve replacement in a patient with severe aortic stenosis who had self-reported allergies to multiple metals. The patient was a 74-year-old man. He developed palmoplantar pustulosis after using a dental prosthesis, and a patch test revealed reactions to several metals; therefore, he was diagnosed with systemic metal allergy. Read More

View Article and Full-Text PDF
September 2021

Development and validation of a simple equation to evaluate dietary protein intake using the blood urea nitrogen/serum creatinine ratio in patients with stage 3 chronic kidney disease.

Int Urol Nephrol 2021 Sep 25. Epub 2021 Sep 25.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.

Purpose: The aim of this research was to develop a simple equation to evaluate dietary protein intake (DPI) in patients with stage 3 chronic kidney disease (CKD) using the blood urea nitrogen (BUN)/serum creatinine (SCr) ratio (BUN/SCr).

Methods: In a prospective cohort of 136 inpatients with stage 3 CKD from 2 centres, the estimated dietary protein intake (DPI) was calculated using Maroni's formula after the patients implemented a 7 day protein-restricted diet. We developed estimation equations based on BUN/SCr and the spot urinary urea nitrogen (UUN)/urinary creatinine (UCr) ratio (UUN/UCr) in combination with sex and body mass index (BMI). Read More

View Article and Full-Text PDF
September 2021

Procedural complications in patients undergoing microsurgical treatment of unruptured intracranial aneurysms: a single-center experience with 1923 aneurysms.

Acta Neurochir (Wien) 2021 Sep 25. Epub 2021 Sep 25.

Department of Neurosurgery, National Brain Aneurysm and Tumor Center, United Hospital, 3033 Excelsior Boulevard, Suite 495, Minneapolis, MN, USA.

Background: With the growing use of endovascular therapy (EVT) to manage unruptured intracranial aneurysms (IAs), detailed information regarding periprocedural complication rates of microsurgical clipping and EVT becomes increasingly important in determining the optimal treatment for individual cases. We report the complication rates associated with open microsurgery in a large series of unruptured IAs and highlight the importance of maintaining surgical skill in the EVT era.

Methods: We reviewed all cases of unruptured IAs treated with open microsurgery by a single neurosurgeon between July 1997 and June 2019. Read More

View Article and Full-Text PDF
September 2021

En-bloc resection of a chordoma in L3 by a combined open posterior and less invasive retroperitoneal approach: technical description and case report.

Arch Orthop Trauma Surg 2021 Sep 25. Epub 2021 Sep 25.

IRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.

Introduction: To fulfill oncological criteria, extensive open anterior and posterior approaches are usually performed in the lumbar spine to obtain an appropriate en-bloc spondylectomy. It is commonly accepted that the price of a tumor-free margin includes such extensive incisions and soft-tissue damage, with consequent relevant blood loss and possible postoperative complications as delayed wound healing. In this article, a case of chordoma in L3 is presented, submitted to an oncologically appropriate en-bloc resection performed by an open posterior approach combined with a mini-retroperitoneal approach. Read More

View Article and Full-Text PDF
September 2021

Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy.

Clin Transl Sci 2021 Sep 25. Epub 2021 Sep 25.

University of Minnesota Medical School, Minneapolis, Minnesota, USA.

There is growing interest in utilizing pharmacogenetic (PGx) testing to guide antidepressant use, but there is lack of clarity on how to implement testing into clinical practice. We administered two surveys at 17 sites that had implemented or were in the process of implementing PGx testing for antidepressants. Survey 1 collected data on the process and logistics of testing. Read More

View Article and Full-Text PDF
September 2021

Inequities in quality and safety outcomes for hospitalized children with intellectual disability.

Dev Med Child Neurol 2021 Sep 25. Epub 2021 Sep 25.

Faculty of Medicine, School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.

Aim: To investigate if there are inequities in quality and safety outcomes for children with intellectual disability admitted to two tertiary paediatric hospitals.

Method: A cross-sectional study of 1367 admissions for 1018 randomly selected patients admitted for more than 23 hours to one of two tertiary children's hospitals in Sydney, Australia (1st January-31st December 2017). Electronic medical records were manually interrogated to identify children with intellectual disability (including developmental delay). Read More

View Article and Full-Text PDF
September 2021

Observation of the therapeutic effect of correcting foot varus on improving knee hyperextension and gait in patients after stroke.

Authors:
Hui-Xian Yu

Curr Neurovasc Res 2021 Sep 23. Epub 2021 Sep 23.

Department of Rehabilitation Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100060, China.

Objective: The present study aimed to observe the therapeutic effect of elastic bandages on improving knee hyperextension in patients with stroke after correcting the foot varus.

Methods: A total of 45 patients with stroke admitted to the hospital from January to August 2019 were enrolled in the present prospective study. Elastic bandages were used to fix the affected foot in a mild valgus position. Read More

View Article and Full-Text PDF
September 2021

Detethering the Superficial Temporal Artery: Application to Tension Free STA-MCA Bypasses.

Clin Anat 2021 Sep 25. Epub 2021 Sep 25.

Department of Neurosurgery, Ochsner Health System, New Orleans, Louisiana, USA.

Background: Extracranial-intracranial bypass has been shown to be effective in the surgical treatment of moyamoya disease, complex aneurysms, and tumors that involve proximal vasculature in carefully selected patients. Branches of the superficial temporal artery (STA) are used commonly for the bypass surgery; however, an appropriate length of the donor vessel must be harvested to avoid failure secondary to anastomotic tension. The goal of this cadaveric study was to investigate quantitatively operative techniques that can increase the STA length available to facilitate tension-free STA-middle cerebral artery (MCA) bypass. Read More

View Article and Full-Text PDF
September 2021

Patients' preferences for quality-of-life aspects in sarcopenia: a best-worst scaling study.

Eur Geriatr Med 2021 Sep 25. Epub 2021 Sep 25.

Division of Public Health, Epidemiology and Health Economics, World Health Organization Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Ageing, University of Liège, Liège, Belgium.

Purpose: As information on patients' preferences regarding quality-of-life aspects in sarcopenia is lacking, this study aims to assess the relative importance of the 14 items of a QoL questionnaire designed for sarcopenia (the SF-SarQoL) using a best-worst scaling (BWS) survey.

Methods: Participants, aged 65 years or older and community dwelling, who previously participated in the SarcoPhAge study, received a BWS survey via the mail. An object case BWS was selected in which participants completed 12 choice tasks, picking the most and least important aspect from 4 out of 14 SF-SarQoL items for each task. Read More

View Article and Full-Text PDF
September 2021

Multiple sclerosis and genetic polymorphisms in fibrinogen-mediated hemostatic pathways: a case-control study.

Neurol Sci 2021 Sep 24. Epub 2021 Sep 24.

Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.

Introduction: Blood coagulation constituents might exert immunomodulatory functions in the CNS and may trigger neuroinflammation and demyelination. We evaluated whether particular single-nucleotide polymorphisms (SNPs), thought to be involved in fibrinogen-mediated hemostatic pathways, are overrepresented in patients with MS compared with controls.

Methods: The case-control study consisted of 119 MS patients recruited consecutively at our clinic, and 68 healthy controls. Read More

View Article and Full-Text PDF
September 2021

Active Learning for Efficient Segmentation of Liver with Convolutional Neural Network-Corrected Labeling in Magnetic Resonance Imaging-Derived Proton Density Fat Fraction.

J Digit Imaging 2021 Sep 24. Epub 2021 Sep 24.

Department of Radiology, Korea University Anam Hospital, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.

This study aimed to propose an efficient method for self-automated segmentation of the liver using magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) through deep active learning. We developed an active learning framework for liver segmentation using labeled and unlabeled data in MRI-PDFF. A total of 77 liver samples on MRI-PDFF were obtained from patients with nonalcoholic fatty liver disease. Read More

View Article and Full-Text PDF
September 2021

Zirconia implants: a promising alternative to titanium?

Evid Based Dent 2021 Jan;22(3):102-103

Aberdeen Dental Hospital, Cornhill Road, Aberdeen, AB25 1ZR, UK.

Design This study is a monocentre cohort study with a primary aim to assess the five-year survival of alumina-toughened zirconia (ATZ) implants (Metoxit AG, Thayngen, Switzerland). Secondary aims were to evaluate peri-implant marginal bone loss (MBL), soft tissue health and patient-reported outcome measures (PROMs). The implants were placed into healed ridges and, following a period of temporisation, were restored with either IPS e. Read More

View Article and Full-Text PDF
January 2021

Are adjunctive therapies effective in reducing gingivitis and plaque?

Evid Based Dent 2021 Jan;22(3):98-99

CT3 Restorative Dentistry, Glasgow Dental Hospital and School, UK.

Data sources PubMed, CENTRAL, Scopus and Cochrane electronic databases were used as the data sources for the systematic review. All randomised control trials that reviewed antiseptics published up to and including 26 February 2019 were included. A manual search of reference lists of the selected studies was conducted, including information from previous systematic reviews conducted by the same authors. Read More

View Article and Full-Text PDF
January 2021

What is the best mechanical device to clean the teeth in periodontal maintenance patients?

Authors:
Erfan Shamsoddin

Evid Based Dent 2021 Jan;22(3):91-93

National Institute for Medical Research Development, Tehran, Iran.

Aim This study evaluates the available clinical evidence with regards to the effectiveness of mechanical oral hygiene devices in patients who are in periodontal maintenance.Data sources A structured online search was conducted in PubMed/Medline, Cochrane Central Register of Controlled Trials (CENTRAL) and Embase. All the databases were explored from initiation to October 2019. Read More

View Article and Full-Text PDF
January 2021

Management of the patient with the open abdomen.

Curr Opin Crit Care 2021 Sep 24. Epub 2021 Sep 24.

Surgical Intensive Care Unit, Shaare Zedek Medical Center and Hebrew University Faculty of Medicine General Intensive Care Unit, Shaare Zedek Medical Center, Jerusalem Intensive Care Unit, Barzilai Medical Center, Ashkelon, Israel Division of Thoracic Surgery, McGill University Health Centre, Montreal, Quebec, Canada Aix Marseille Université, Assistance Publique Hôpitaux Universitaire de Marseille, Department of Anesthesiology and Intensive Care Unit, Nord Hospital, Marseille, France.

Purpose Of Review: The aim of this study was to outline the management of the patient with the open abdomen.

Recent Findings: An open abdomen approach is used after damage control laparotomy, to decrease risk for postsurgery intra-abdominal hypertension, if reoperation is likely and after primary abdominal decompression.Temporary abdominal wall closure without negative pressure is associated with higher rates of intra-abdominal infection and evisceration. Read More

View Article and Full-Text PDF
September 2021

Association of Counseling and Psychotherapy on Retention in Medication for Addiction Treatment Within a Large Medicaid Population.

J Addict Med 2021 Sep 22. Epub 2021 Sep 22.

Community Care Behavioral Health Organization, UPMC Insurance Services Division, Pittsburgh, PA (KE, JS, AH, DL, GN, MM, MH, NR), UPMC Health Plan (PH), University of Pittsburgh Department of Psychiatry, Pittsburgh, PA (NR).

Objectives: Buprenorphine/naloxone is an effective medication for the treatment of opioid use disorder. Unlike methadone, which can only be dispensed in federally waived clinics and which must be combined with specific psychosocial treatment, buprenorphine can be dispensed by individual prescribers who have completed an 8-hour training program, with no requirement that patients receive concomitant psychotherapy. The objective of this study is to quantify the association of counseling and psychotherapy on retention in treatment. Read More

View Article and Full-Text PDF
September 2021

Nucleolar protein 6 promotes cell proliferation and acts as a potential novel prognostic marker for hepatocellular carcinoma.

Chin Med J (Engl) 2021 Sep 21. Epub 2021 Sep 21.

National Engineering Research Center for Miniaturized Detection Systems, The College of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, China Department of Surgical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.

Background: Nucleolar protein 6 (NOL6) is a nucleolar RNA-associated protein that is highly conserved between species. It has been proved to be associated with the prognosis of liver cancer. However, the underlying mechanism has not been fully established. Read More

View Article and Full-Text PDF
September 2021

Improving communication on medical ward rounds with patients who speak limited English with implementation of medical communication charts.

BMJ Open Qual 2021 Sep;10(3)

Department of Respiratory Medicine, King's College Hospital, London, UK

Aim: To improve communication on the medical ward round with patients with limited English through implementation of a medical communication chart.

Local Problem: King's College Hospital (KCH), London, is situated in Southwark in which 11% of households have no members that speak English as a first language, 4.1% of London's population report they do not speak English well. Read More

View Article and Full-Text PDF
September 2021

mTOR inhibitors and risk of ovarian cysts: a systematic review and meta-analysis.

BMJ Open 2021 Sep 24;11(9):e048190. Epub 2021 Sep 24.

Department of Clinical Sciences and Community Health, Università degli Studi di Milano Facoltà di Medicina e Chirurgia, Milano, Lombardia, Italy.

Objective: To summarise the available evidence on frequency of ovarian cyst development during mammalian target of rapamycin inhibitors (mTORi) treatment.

Methods: PubMed/Medline and EMBASE databases were searched, from 1990 up to March 2020, using the following keywords: 'tacrolimus', 'sirolimus', 'temsirolimus', 'everolimus', 'deforolimus', 'mTOR' and 'ovarian cysts' (Limit: Human, English, full article). Studies were selected for the review if they met the following criteria: clinical studies, studies reporting original data, studies reporting the number of patients using mTORi, studies reporting the number of patients with ovarian cysts. Read More

View Article and Full-Text PDF
September 2021

Venoarterial Extracorporeal Membrane Oxygenation in Severe Drug Intoxication: A Retrospective Comparison of Survivors and Nonsurvivors.

ASAIO J 2021 Sep 20. Epub 2021 Sep 20.

From the Department of Intensive Care, CHU Lille, Lille, France University of Lille, Inserm U1167, Institut Pasteur de Lille, Lille, France Department of Cardiovascular Surgery, CHU Lille, Lille, France Cardiovascular Intensive Care Unit, CHU Lille, Lille, France University of Lille, Inserm U1011, Institut Pasteur de Lille, EGID, Lille, France Emergency Department and SAMU, CHU Lille, Lille, France University of Lille, Inserm U1285, CNRS UMR 8576, Lille, France.

Selecting patients most likely to benefit from venoarterial extracorporeal membrane oxygenation (V-A ECMO) to treat refractory drug-induced cardiovascular shock remains a difficult challenge for physicians. This study reported short-term survival outcomes and factors associated with mortality in V-A ECMO-treated patients for poisoning. Twenty-two patients placed on V-A ECMO after drug intoxication from January 2014 to December 2020 were retrospectively analyzed. Read More

View Article and Full-Text PDF
September 2021

Stability of Symptom Clusters in Patients With Gynecologic Cancer Receiving Chemotherapy.

Cancer Nurs 2021 Sep 23. Epub 2021 Sep 23.

Author Affiliations: Phyllis F. Cantor Center for Research in Nursing and Patient Care Services, Dana-Farber Cancer Institute (Drs Pozzar and Hammer), Boston, Massachusetts; School of Nursing (Drs Cooper, Kober, Paul, and Miaskowski) and School of Medicine, University of California, San Francisco (Drs Chen, Levine, and Miaskowski); School of Nursing, University of Pittsburgh (Dr Conley), Pennsylvania; Mount Sinai Medical Center (Dr Cartwright), New York, New York; and Rory Myers College of Nursing, New York University (Dr Wright), New York.

Background: Patients with gynecologic cancer undergoing chemotherapy experience multiple co-occurring symptoms. Understanding how symptom clusters change over time is essential to the development of interventions that target multiple co-occurring symptoms.

Objective: The aim of this study was to assess the relative stability of symptom clusters across a chemotherapy cycle in patients with gynecologic cancer. Read More

View Article and Full-Text PDF
September 2021

Radiomic modeling to predict risk of vertebral compression fracture after stereotactic body radiation therapy for spinal metastases.

J Neurosurg Spine 2021 Sep 24:1-9. Epub 2021 Sep 24.

1Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore.

Objective: In the treatment of spinal metastases with stereotactic body radiation therapy (SBRT), vertebral compression fracture (VCF) is a common and potentially morbid complication. Better methods to identify patients at high risk of radiation-induced VCF are needed to evaluate prophylactic measures. Radiomic features from pretreatment imaging may be employed to more accurately predict VCF. Read More

View Article and Full-Text PDF
September 2021

Patient outcomes after circumferential minimally invasive surgery compared with those of open correction for adult spinal deformity: initial analysis of prospectively collected data.

J Neurosurg Spine 2021 Sep 24:1-12. Epub 2021 Sep 24.

1Department of Neurosurgery, University of California, San Francisco, San Francisco, California.

Objective: Circumferential minimally invasive spine surgery (cMIS) for adult scoliosis has become more advanced and powerful, but direct comparison with traditional open correction using prospectively collected data is limited. The authors performed a retrospective review of prospectively collected, multicenter adult spinal deformity data. The authors directly compared cMIS for adult scoliosis with open correction in propensity-matched cohorts using health-related quality-of-life (HRQOL) measures and surgical parameters. Read More

View Article and Full-Text PDF
September 2021

"That was quick, simple, and easy": Patient perceptions of acceptability of point-of-care hepatitis C RNA testing at a reception prison.

Int J Drug Policy 2021 Sep 21;99:103456. Epub 2021 Sep 21.

The Kirby Institute, UNSW Sydney, Level 6, Wallace Wurth Building, Sydney, NSW, 2052, Australia.

Introduction: Current diagnostic pathways require multiple healthcare provider visits and lead to a drop-off in the hepatitis C virus (HCV) testing and treatment care cascade. In prison settings, frequent transitioning between prisons and the community further reduces uptake of testing and treatment. The PIVOT study evaluated a 'one-stop-shop' intervention integrating point-of-care HCV RNA testing, Fibroscan®-based liver disease assessment, and treatment prescription at a reception prison in Australia. Read More

View Article and Full-Text PDF
September 2021

Variability in subthalamic nucleus targeting for deep brain stimulation with 3 and 7 Tesla magnetic resonance imaging.

Neuroimage Clin 2021 Sep 16;32:102829. Epub 2021 Sep 16.

Integrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, Amsterdam, The Netherlands.

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective surgical treatment for Parkinson's disease (PD). Side-effects may, however, be induced when the DBS lead is placed suboptimally. Currently, lower field magnetic resonance imaging (MRI) at 1. Read More

View Article and Full-Text PDF
September 2021

Simulation in disaster nursing education: A scoping review.

Nurse Educ Today 2021 Aug 30;107:105119. Epub 2021 Aug 30.

School Of Health Sciences, Wuhan University, Located on No. 115 Donghu Road, Wuhan, Hubei province 430071, China. Electronic address:

Objectives: Disasters are gradually increasing in type and frequency throughout the globe. Simulation is being used in disaster nursing teaching and training. The aim of this scoping review was to systematically map the extent and application of simulation in disaster nursing education. Read More

View Article and Full-Text PDF