7,782 results match your criteria patients scleral

Safety and Efficacy of Current Sclera Fixation Methods for Intraocular Lenses and Literature Overview.

Klin Monbl Augenheilkd 2021 Apr 14. Epub 2021 Apr 14.

Augenklinik und Poliklinik, Klinikum der Universität München, LMU München, Deutschland.

Background: Evaluation of the three currently most common techniques for intraocular lens (IOL) sclera fixation: (1) Prolene suture with Hoffman sclera pocket (2) four-point GoreTex suture technique (3) sutureless flanged intrascleral IOL fixation with double-needle ("Yamane") technique.

Material And Methods: Retrospective, clinical case series (chart review) at the Department of Ophthalmology, Ludwig-Maximilians-University (LMU), Munich, Germany. Enrolled in the study were 51 patients with 55 eyes. Read More

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Decreased choroidal and scleral thicknesses in highly myopic eyes with posterior staphyloma.

Sci Rep 2021 Apr 12;11(1):7987. Epub 2021 Apr 12.

Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Korea.

In this cross-sectional study, we investigated choroidal thickness (CT) and scleral thickness (ST) in highly myopic eyes and their associations with ocular factors. Patients underwent widefield swept-source optical coherence tomography (OCT) to measure the CT and ST at the subfovea and 3000 μm superior, inferior, temporal, and nasal to the fovea and macular curvature. A total of 237 eyes (154 patients) were included. Read More

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Observed Frequency and Characteristics of Hearing Loss in Osteogenesis Imperfecta.

Rev Med Chil 2020 Dec;148(12):1781-1786

Department of Pediatric Endocrinology, UC Christus Health Center, Pontificia Universidad Católica de Chile, Chile.

Background: Osteogenesis imperfecta (OI) is a rare group of genetic disorders affecting connective tissue, with consequent bone fragility, frequent fractures and skeletal deformity. Depending on the type, patients can have blue sclera, dentinogenesis imperfecta, and hearing loss.

Aim: To determine the frequency, type and audiometric characteristics of hearing loss in a group of patients with OI. Read More

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December 2020

Pediatric rhegmatogenous retinal detachment: predictors of anatomic and functional success.

Int Ophthalmol 2021 Apr 11. Epub 2021 Apr 11.

Instituto de Oftalmología Conde de Valenciana IAP, Mexico City, Mexico.

Purpose: This study describes presenting clinical features and surgical techniques associated with successful repair of pediatric rhegmatogenous retinal detachment (RRD).

Methods: This is a retrospective case series which involved 242 cases younger than 18 years with new-onset RRD with descriptive statistics for the full group. Further exclusion established 168 cases that underwent surgery with minimum 3-month follow-up. Read More

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Long-term ocular biometric variations after scleral buckling surgery in macula-on rhegmatogenous retinal detachment.

BMC Ophthalmol 2021 Apr 10;21(1):172. Epub 2021 Apr 10.

Ophthalmology Unit - Department of Sense Organs, Sapienza University of Rome - Policlinico Umberto I University Hospital, Rome, Italy.

Background: Myopic shift and biometric ocular changes have been previously observed after scleral buckling (SB) surgery in rhegmatogenous retinal detachment (RRD), but long term-term outcomes had not yet been explored. The purpose of present study is to evaluate long term ocular biometric changes in patients with primary macula-on RRD treated with SB.

Methods: In this retrospective, observational study, we reviewed the medical records of patients undergoing SB surgery for macula-on RRD. Read More

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Bandage lens for treatment of corneosclera melting two weeks after pterygium surgery: A case report.

Medicine (Baltimore) 2021 Apr;100(14):e25348

Eye Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, China.

Introduction: Pterygium is a common chronic ocular surface condition in ophthalmology.At present, the main treatment modality is surgical resection. Although the recurrence rate can be controlled to varying degrees, some patients can still develop serious complications, such as scleral melting, corneal melting, and even corneal perforation. Read More

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Refractive outcome of trocar-assisted sutureless scleral fixation with 3-piece intraocular lenses.

Int Ophthalmol 2021 Apr 7. Epub 2021 Apr 7.

Department of Ophthalmology, Faculty of Medicine, Goztepe Training and Research Hospital, Istanbul Medeniyet University, Kadikoy, Istanbul, Turkey.

Purpose: Intraocular lens (IOL) implantation with a trocar-assisted sutureless scleral fixation technique is a relatively new IOL implantation approach for aphakic eyes. During this surgery, the intrascleral position of the haptics can change the location of the IOL optic and may alter the refractive outcome. This study aimed to evaluate the refractive outcome of this surgery. Read More

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Multifocal Electroretinogram in Keratoconus Patients without and with Scleral Lenses.

Curr Eye Res 2021 Apr 7. Epub 2021 Apr 7.

Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics, University of Minho. Braga Portugal.

: To investigate changes in the multifocal electroretinogram (mfERG) response in eyes with keratoconus when corrected with scleral lenses (SL) compared with the best correction in glasses.: The mfERG response s in 10 eyes with keratoconus were recorded with the best correction using both a trial frame (baseline) and a hexafocon A SL using an electrophysiological diagnostic system. Electrophysiologic measurements were performed with the pupils fully dilated with instillation of 1% phenylephrine. Read More

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Lipid Peroxidation in Subretinal Fluid: Some Light on the Prognosis Factors.

Biomolecules 2021 Mar 30;11(4). Epub 2021 Mar 30.

Thematic Cooperative Health Network for Research in Ophthalmology (Oftared), Carlos III Health Institute, 28220 Madrid, Spain.

The aim of this study was to identify a relation between the clinical characteristics and differences in lipid peroxidation in the subretinal fluid (SRF) of rhegmatogenous retinal detached patients by malondialdehyde (MDA) quantification. We collected 65 SRF samples from consecutive patients during scleral buckling surgery in rhegmatogenous retinal detachment (RRD) eyes. In addition to a complete ophthalmic evaluation, we studied the refractive status, evolution time, and the number of detached retinal quadrants to establish the extension of RRD. Read More

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Investigating the Relationship between Glaucoma Prevalence and Trabecular Meshwork Length.

J Clin Med 2021 Mar 5;10(5). Epub 2021 Mar 5.

Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul 03722, Korea.

Glaucoma is one of the most common causes of blindness worldwide, but the risk factors of glaucoma are yet to be fully understood. We investigated the relationship between the prevalence of glaucoma and trabecular meshwork (TM) length by comparing the mean TM length of a South Korean population with that of another ethnic population. We included 250 eyes of 125 patients who underwent anterior segment optical coherence tomography at Yonsei University Gangnam Severance Hospital between January 2015 and December 2017. Read More

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Intratumor Heterogeneity in Uveal Melanoma BAP-1 Expression.

Cancers (Basel) 2021 Mar 7;13(5). Epub 2021 Mar 7.

Departments of Ophthalmology and Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Malignant tumors are rarely homogenous on the morphological, genome, transcriptome or proteome level. In this study, we investigate the intratumor heterogeneity of BAP-1 expression in uveal melanoma with digital image analysis of 40 tumors. The proportion of BAP-1 positive cells was measured in full tumor sections, hot spots, cold spots and in scleral margins. Read More

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A Case Series of "Solitary Idiopathic Choroiditis" and Proposal of a Nomenclature Change to "Idiopathic Scleroma".

Ocul Oncol Pathol 2021 Mar 10;7(1):48-53. Epub 2020 Nov 10.

Ophthalmology Department, Moorfields Eye Hospital, London, United Kingdom.

Objective: To define the characteristics of solitary idiopathic choroiditis (SIC) in a consecutive series of patients and propose a nomenclature change to idiopathic scleroma.

Materials And Methods: Electronic patient records were retrospectively interrogated to identify all patients diagnosed with SIC between 2002 and 2019 in a tertiary referral ophthalmic hospital in the United Kingdom.

Results: Thirty-four eyes of 34 patients were found to have SIC. Read More

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Epiretinal Membrane Surgery After Retinal Detachment Repair: Visual Acuity Outcomes and Optical Coherence Tomography Analysis.

Ophthalmol Retina 2021 Mar 29. Epub 2021 Mar 29.

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, PA. Electronic address:

Purpose: To assess visual acuity (VA) outcomes of epiretinal membrane (ERM) surgery following primary rhegmatogenous retinal detachment (RD) repair.

Design: Retrospective, consecutive case series.

Subjects: Eyes undergoing pars plana vitrectomy (PPV) with membrane peel (MP) surgery for ERM following primary RD repair (PPV with or without scleral buckle (SB) and gas tamponade). Read More

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Ophthalmic manifestations in Kabuki (make-up) syndrome: A single-center pediatric cohort and systematic review of the literature.

Eur J Med Genet 2021 Mar 29:104210. Epub 2021 Mar 29.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; The Institute for Rare Diseases, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel. Electronic address:

Kabuki syndrome (KS) is a genetic disorder caused by pathogenic variants in KMT2D or KDM6A, and manifesting with multi-systemic involvement, including recognizable facial features, developmental delay and multiple congenital anomalies. Ophthalmological involvement has been described in varying rates in several studies. We aimed to evaluate the prevalence and nature of ophthalmological findings in a cohort of KS patients in Israel. Read More

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Factors Determining the Morphology of Peripapillary Retinoschisis.

Clin Ophthalmol 2021 25;15:1293-1300. Epub 2021 Mar 25.

Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan.

Purpose: We conducted cross-sectional examinations to determine the frequency of peripapillary retinoschisis (PRS) in eyes with glaucoma and suspected glaucoma and analyzed the pathogenesis of PRS by using spectral-domain optical coherence tomography (SD-OCT).

Patients And Methods: In 1516 cases involving glaucoma and suspected glaucoma, we retrospectively reviewed the disc and macular volume scans obtained by SD-OCT and categorized PRS into two groups based on whether the retinoschisis was closer to the optic nerve over the Bruch's membrane opening (BMO) (ahead group) or did not go past the BMO (behind group) and then compared the characteristics between both groups.

Results: The total frequency of PRS was 1. Read More

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Drain fluid cryo-explant technique for treatment of superior bullous rhegmatogenous retinal detachment in young adults.

Ther Adv Ophthalmol 2021 Jan-Dec;13:2515841420988211. Epub 2021 Jan 20.

Department of Ophthalmology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Purpose: To evaluate the efficacy of the drain fluid cryo-explant (DFCE) technique for the management of uncomplicated superior bullous rhegmatogenous retinal detachment (RRD) in young adults.

Patients And Methods: A retrospective study that included eyes with uncomplicated superior bullous RRD in patients ⩽40 years old. DFCE technique consists of sequential drainage of subretinal fluid, intravitreal fluid injection, cryotherapy, and placement of a scleral explant(s). Read More

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January 2021

MRI and dual-energy CT fusion anatomic imaging in Ru-106 ophthalmic brachytherapy.

Brachytherapy 2021 Mar 27. Epub 2021 Mar 27.

Department of Ophthalmology, University Hospital of Heraklion, Crete, Greece.

Purpose: Brachytherapy with Ru-106 is widely used for the treatment of intraocular tumors, and its efficacy depends on the accuracy of radioactive plaque placement. Ru-106 plaques are MRI incompatible and create severe metal artifacts on conventional CT scans. Dual-energy CT scans (DECT) may be used to suppress such artifacts. Read More

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Infectious endophthalmitis after scleral fixation of an intraocular lens.

Retina 2021 Mar 24. Epub 2021 Mar 24.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Borame Hospital, Seoul, Korea Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea Department of Ophthalmology, College of Medicine, Kosin University, Gospel Hospital, Busan, Korea Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Purpose: To determine the mechanism of infection, clinical features, and risk factors of endophthalmitis after scleral fixation of an intraocular lens (IOL).

Methods: We included fifteen patients with infectious endophthalmitis after scleral fixation of an IOL between April 2004 and December 2017, as well as four patients found through a literature search. Thus, a total of nineteen patients were analyzed. Read More

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Effect of Penetration Angle and Velocity During Intravitreal Injection on Pain.

Semin Ophthalmol 2021 Mar 29:1-7. Epub 2021 Mar 29.

Department of Ophthalmology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.

To evaluate the effect of velocity and angle of the intravitreal injection of anti-vascular endothelial growth factors on pain sensation. Patients were randomly assigned to one of four injection methods: straight and fast, straight and slow, tunneled and fast, and tunneled and slow. Later, they graded their pain sensation on a Visual Analog Scale (range 0-10). Read More

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Reper intraocular lens with artificial iris: implantation techniques and outcomes.

Eur J Ophthalmol 2021 Mar 28:11206721211005693. Epub 2021 Mar 28.

Department of Ophthalmology of University of Padova, Padova, Italy.

The authors describe the surgical techniques to implant a novel intraocular lens with artificial iris (Reper) in patients affected by traumatic aphakia and aniridia. Two surgical approaches are proposed: implantation by suture-loaded cartridge and "open sky" implantation combined with penetrating keratoplasty. The method of establishing the exact position of the scleral fixation points and the pre-assembly of the suture of Reper before its implantation are the main novel proposed surgical procedures. Read More

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Needle guided ab interno technique for tube insertion through the ciliary sulcus in uncontrolled glaucoma.

Eur J Ophthalmol 2021 Mar 28:11206721211007093. Epub 2021 Mar 28.

Research Unit, Clínica Vista, Lima, Peru.

Purpose: To describe a modified ab interno technique for the tube implantation from a glaucoma draining device into the ciliary sulcus.

Materials And Methods: The modified ab interno technique was performed on four eyes of four patients.

Results: After the plate was fixed, a 21G needle is inserted through a paracentesis 180° away from the tube position into the anterior chamber and advanced to the posterior chamber through the sclera; finally, the needle exits the eye, then the tube is inserted into the lumen of the needle. Read More

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Machine learning prediction of pathologic myopia using tomographic elevation of the posterior sclera.

Sci Rep 2021 Mar 26;11(1):6950. Epub 2021 Mar 26.

Department of Ophthalmology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Qualitative analysis of fundus photographs enables straightforward pattern recognition of advanced pathologic myopia. However, it has limitations in defining the classification of the degree or extent of early disease, such that it may be biased by subjective interpretation. In this study, we used the fovea, optic disc, and deepest point of the eye (DPE) as the three major markers (i. Read More

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Microbiological Evaluation of Opened Saline Bottles for Scleral Lens Use and Hygiene Habits of Scleral Lens Patients.

Optom Vis Sci 2021 Mar;98(3):250-257

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California University Eye Institute, University of Houston College of Optometry, Houston, Texas USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California

Significance: Scleral lenses have become a widely used treatment option for patients with irregular corneas and ocular surface disease. Successful wear entails use of a nonpreserved saline solution to fill the lens before application on the eye.

Purpose: The purposes of this study were to evaluate solution from opened bottles of multidose preservative-free saline for microbiological growth and to better understand study participant hygiene habits while handling these bottles for scleral lens wear. Read More

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Comparative Analysis of Two Clinical Diagnostic Methods of the Corneoscleral Geometry.

Eye Contact Lens 2021 Mar 22. Epub 2021 Mar 22.

Group of Optics and Visual Perception (L.B., A.M.-M., D.P.P.), Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain; and Department of Ophthalmology (D.P.P.), Vithas Medimar International Hospital, Alicante, Spain.

Purpose: To compare the sagittal height (SH) measurements and best fit sphere (BFS) scleral curvature obtained with two different diagnostic technologies.

Methods: Prospective, nonrandomized, and comparative study analyzing 23 healthy eyes of 23 patients (age, 14-52 years) was conducted. A complete eye examination was performed including a corneoscleral topographic analysis with the Scheimpflug camera-based system Pentacam (Oculus GmbH, Wetzlar, Germany) and afterward with the Fourier domain profilometer Eye Surface Profiler (ESP) (Eaglet-Eye, Houten, the Netherlands). Read More

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Diagnoses and Outcomes of Prosthetic Replacement of the Ocular Surface Ecosystem Treatment-A Canadian Experience.

Eye Contact Lens 2021 Mar 16. Epub 2021 Mar 16.

Faculty of Medicine (B.M.W. and A.G.), University of Toronto, Toronto, Canada; Department of Ophthalmology and Vision Sciences (T.T., M.M., M.C., C.C.C., and A.R.S.), University of Toronto, Toronto, Canada; Kensington Eye Institute (T.T., M.M., S.R., J.L., M.C., C.C.C., and A.R.S.), Toronto, Canada; and New England College of Optometry (J.L.), Boston, MA.

Objectives: To investigate underlying diagnoses and outcomes of patients undergoing Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment at the first Canadian PROSE center.

Methods: A retrospective chart review was conducted on patients referred for PROSE treatment and fitted with PROSE devices from 2018 to 2020. Data were collected on diagnoses, presenting symptoms, previous lens modalities attempted, best-corrected visual acuities (BCVAs) pre-PROSE and post-PROSE, daily wear time, and failure rates. Read More

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The effect of scleral lenses on vision, refraction and aberrations in post-LASIK ectasia, keratoconus and pellucid marginal degeneration.

Ophthalmic Physiol Opt 2021 Mar 26. Epub 2021 Mar 26.

Centre for Vision and Eye Research, School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia.

Purpose: To quantify the effect of a single scleral lens design on visual acuity and ocular higher-order aberrations in eyes with post-LASIK ectasia, keratoconus and pellucid marginal degeneration (PMD) that could not achieve satisfactory vision with spectacles or soft contact lenses.

Methods: Forty-six eyes of 28 participants fitted with diagnostic scleral lenses (KeraCare) were analysed, including 19, 15 and 12 eyes with post-LASIK ectasia, keratoconus and PMD, respectively. Corrected distance visual acuity (CDVA) and ocular aberrations were measured prior to lens wear and during lens wear after 60 min of settling. Read More

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Biopsy-proven liver cirrhosis in young children: A 10-year cohort study.

J Viral Hepat 2021 Mar 24. Epub 2021 Mar 24.

The Fifth Medical Center (formerly Beijing 302 Hospital), Chinese PLA General Hospital, Beijing, China.

Young children with liver cirrhosis have a significantly high risk of mortality. However, there are few studies regarding early childhood-onset cirrhosis. This study aims to explore the causes, clinical findings and prognosis of biopsy-proven cirrhosis in infants, toddlers and preschoolers. Read More

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Repositioning surgery of different intraocular lens designs in eyes with late in-the-bag intraocular lens dislocation.

J Cataract Refract Surg 2021 Jan 29. Epub 2021 Jan 29.

1Department of Ophthalmology, Oslo University Hospital, Oslo, Norway 2Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Purpose: To evaluate the long-term efficacy and safety after intraocular lens (IOL) repositioning by scleral suturing of 1-piece IOL compared with other IOL designs in the treatment of late in-the-bag IOL dislocation.

Setting: Patients referred to Oslo University Hospital.

Design: Prospective cohort study. Read More

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January 2021

Accuracy of Computed Tomography and Magnetic Resonance Imaging for Detection of Pathologic Risk Factors in Patients Diagnosed with Retinoblastoma.

Curr Eye Res 2021 Mar 22:1-7. Epub 2021 Mar 22.

Department of Ophthalmology, Chiang Mai University, Chiang Mai, Thailand.

: To assess and compare the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) for detecting the extent of tumor invasion in eyes with advanced retinoblastoma prior to enucleation using histopathologic analysis as a reference.: A total of 56 patients (68 eyes) enucleated for retinoblastoma were reviewed. Eyes with complete data (CT 28, MRI 16) were included for analysis. Read More

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Infectious necrotizing scleritis and proliferative vitreoretinopathy after scleral buckling in a patient with atopic dermatitis.

Am J Ophthalmol Case Rep 2021 Jun 8;22:101066. Epub 2021 Mar 8.

Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, 93125441, Japan.

Purpose: To report a case of necrotizing scleritis and proliferative vitreoretinopathy due to an acute infection following scleral buckling for the management of rhegmatogenous retinal detachment in a patient with untreated atopic dermatitis.

Observations: A 40-year-old man with untreated atopic dermatitis presented with rhegmatogenous retinal detachment in his right eye. He underwent uncomplicated scleral buckling surgery with an encircling silicon sponge band, then noticed severe hyperemia and purulent discharge in the eye at 3 weeks after surgery. Read More

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