16,823 results match your criteria patients paroxysmal


Identification of local atrial conduction heterogeneities using high-density conduction velocity estimation.

Europace 2021 May 10. Epub 2021 May 10.

Unit Translational Electrophysiology, Department of Cardiology, Erasmus Medical Centre, Dr. Molewaterplein 40, 3015GD Rotterdam, the Netherlands.

Aims: Accurate determination of intra-atrial conduction velocity (CV) is essential to identify arrhythmogenic areas. The most optimal, commonly used, estimation methodology to measure conduction heterogeneity, including finite differences (FiD), polynomial surface fitting (PSF), and a novel technique using discrete velocity vectors (DVV), has not been determined. We aim (i) to identify the most suitable methodology to unravel local areas of conduction heterogeneities using high-density CV estimation techniques, (ii) to quantify intra-atrial differences in CV, and (iii) to localize areas of CV slowing associated with paroxysmal atrial fibrillation (PAF). Read More

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Systematic Review of Bilateral Benign Paroxysmal Positional Vertigo.

Laryngoscope 2021 May 10. Epub 2021 May 10.

Division of Otolaryngology - Head & Neck Surgery, McMaster University, Hamilton, Ontario, Canada.

Objectives: To evaluate the success rates of canalith repositioning maneuvers (CRM) in the treatment of patients diagnosed with bilateral benign paroxysmal positional vertigo (BiBPPV).

Study Design: Systematic review.

Methods: A comprehensive search of only English studies in PubMed, Ovid (1946 to the present), and Embase (1974 to the present) databases was done up until January 1, 2021. Read More

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Atrial thrombus detection on transoesophageal echocardiography in patients with atrial fibrillation undergoing cardioversion or catheter ablation: A pooled analysis of rates and predictors.

J Cardiovasc Electrophysiol 2021 May 9. Epub 2021 May 9.

Non-Communicable Diseases Research Unit, South African Medical Research Council, Durban and Cape Town, South Africa.

Objective: To summarize data on the rates and predictors of left atrial/left atrial appendage thrombus (LAT/LAAT) detection by transoesophageal echocardiography (TEE) prior to electrical cardioversion (ECV) or catheter ablation (CA) for atrial fibrillation (AF).

Methods: EMBASE, MEDLINE, and Web of Science were searched to identify all studies providing relevant data and published by October 07, 2020. Random-effects meta-analysis method was used to pool estimates. Read More

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Prevalence of Occipital Neuralgia at a Community Hospital-based Headache Clinic.

Neurol Clin Pract 2021 Feb;11(1):6-12

Department of Neurology (PGM), Brigham and Women's Hospital, Boston; Department of Neurology (PGM), Harvard Vanguard Medical Associates, Braintree; Division of Neurology (PGM), Cambridge Health Alliance; Harvard Medical School (PGM), Boston, MA; Department of Neurology (UN), West Virginia University, School of Medicine, Morgantown, WV; St. George's University (SK), School of Medicine, Grenada, WI; Hackensack Meridian School of Medicine at Seton Hall University (RK), Nutley; and Neuroscience Institute at Hackensack University Medical Center (RK), Hackensack, NJ.

Background: Occipital neuralgia (ON) is a paroxysmal disorder involving lancinating pain that originates in the neck or skull base with superior radiation toward the apex. ON more commonly occurs in patients with other coexisting headache disorders. There are limited data regarding the prevalence of ON. Read More

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February 2021

Zuma Modified Maneuver as a Treatment to Geotropic Lateral Semicircular Canal Benign Paroxysmal Positional Vertigo.

Int Arch Otorhinolaryngol 2021 Apr 23;25(2):e255-e257. Epub 2020 Jun 23.

Department of Otorhinolaryngology, Pontifícia Universidade Católica, INSCER, Rio Grande do Sul, Porto Alegre, RS, Brazil.

 Benign Paroxysmal Positional Vertigo (BPPV) is the most common vestibular disorder, resulting from detached otoliths that migrate to one of the semicircular canals - canalolithiasis - or one of the cupulas - cupulolithiasis. The present study is related to lateral canal BPPVs, which may be either geotropic or apogeotropic. The geotropic variant of lateral semicircular canal benign paroxysmal positional vertigo (LC-BPPV) is attributed to free floating particles in the posterior arm of the lateral semicircular canal. Read More

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A single Epley manoeuvre can improve self-perceptions of disability (quality of life) in patients with pc-BPPV: A randomised controlled trial in primary care.

Aten Primaria 2021 May 6;53(8):102077. Epub 2021 May 6.

Unitat de Suport a la Recerca Metropolitana Sud, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Cornellà, Barcelona, Spain.

Posterior canal benign paroxysmal positional vertigo (pc-BPPV) causes physical, functional, and emotional impairment. The treatment is the Epley manoeuvre (EM).

Objective: The purpose of the study was to compare the impact of the EM and a sham manoeuvre in primary care on self-perceived disability. Read More

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Vestibular disorders in children: A retrospective analysis of vestibular function test findings.

Int J Pediatr Otorhinolaryngol 2021 Apr 29;146:110751. Epub 2021 Apr 29.

Acibadem Maslak Hospital ENT Department, Istanbul, Turkey.

Objective: This study was designed to describe the most common vestibular disorders in children and their associated findings on vestibular function testing.

Method: Data from 203 children with a mean age of 11.16 ± 3. Read More

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Pulsed field ablation selectively spares the oesophagus during pulmonary vein isolation for atrial fibrillation.

Europace 2021 May 7. Epub 2021 May 7.

IHU LIRYC-CHU Bordeaux, Univ. Bordeaux, Inserm U1045, Avenue du Haut Lévêque, 33604 Pessac, France.

Aims: Extra-atrial injury can cause complications after catheter ablation for atrial fibrillation (AF). Pulsed field ablation (PFA) has generated preclinical data suggesting that it selectively targets the myocardium. We sought to characterize extra-atrial injuries after pulmonary vein isolation (PVI) between PFA and thermal ablation methods. Read More

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Prevalence of Medically Resistant Epilepsy in Saudi Arabia.

Neuroepidemiology 2021 May 6:1-7. Epub 2021 May 6.

King Fahad University Hospital, Alkhobar, Saudi Arabia.

Objectives: The objective of this study was to evaluate the prevalence of medically resistant epilepsy (MRE) in our hospital and to compare the prevalence with that in other populations.

Methods: We retrospectively analyzed the data of patients who visited the epilepsy clinics at King Fahd University Hospital, Al-Khobar, Saudi Arabia between January 2017 and December 2018. This study included patients aged ≥14 years who had at least 2 unprovoked seizures 24 h apart. Read More

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The impact of basic atrial rhythm during catheter ablation of atrial fibrillation on clinical outcomes: Lessons from the German Ablation Registry.

J Cardiovasc Electrophysiol 2021 May 5. Epub 2021 May 5.

Universitäres Herz- und Gefäßzentrum Hamburg-Eppendorf, Department of Cardiology, Hamburg, Germany.

Background: The impact of basic atrial rhythm (sinus rhythm (SR) vs atrial fibrillation (AF)) during AF ablation on efficacy and safety is unknown.

Methods: 3375 patients from the German Ablation Registry undergoing first-time AF ablation were divided according to the type of AF and the basic atrial rhythm during the ablation procedure: paroxysmal AF (PAF) and SR [group Ia], PAF and AF [group Ib]), persistent AF and SR (IIa) and persistent AF and AF (IIb).

Results: Patients in SR (n=2312 (67%)) underwent cryoballoon ablation more often (Ia vs Ib p=0. Read More

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Quality of life and healthcare utilisation improvements after atrial fibrillation ablation.

Heart 2021 May 5. Epub 2021 May 5.

Department of Cardiology, AZ Sint-Jan AV, Bruges, WVL, Belgium.

Objective: Pulmonary vein isolation (PVI) guided by a standardised CLOSE (contiguous optimised lesions) protocol has been shown to increase clinical success after catheter ablation for paroxysmal atrial fibrillation (PAF). This study analysed healthcare utilisation and quality of life (QOL) outcomes from a large multicentre prospective study, measured association between QOL and atrial fibrillation (AF) burden and identified factors associated with lack of QOL improvement.

Methods: CLOSE-guided ablation was performed in 329 consecutive patients (age 61. Read More

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A prospective survey of atrial fibrillation management in Iran: Baseline results of the Iranian Registry of Atrial Fibrillation (IRAF).

Int J Clin Pract 2021 May 5:e14313. Epub 2021 May 5.

Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Background: Atrial fibrillation. (AF) is the most common sustained arrhythmia globally and its prevalence is likely to increase in the next decades due to increasing age and co-morbidities. There are no data on demographic features, clinical characteristics, associated comorbidities, and practice patterns of AF in Iran. Read More

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COVID-19-Associated Ischemic Stroke in a Patient on Therapeutic Anticoagulation.

Neurologist 2021 May 5;26(3):108-111. Epub 2021 May 5.

Medicine, University of Florida College of Medicine, Jacksonville, FL.

Introduction: The coronavirus disease 2019 (COVID-19) has been associated with a hypercoagulable state, increasing the risk for ischemic stroke. In select cases, patients are already on anticoagulation therapy. Such examples highlight the severity of COVID-19's hyperthrombotic state, and raise questions regarding optimal stroke prevention in these patients. Read More

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Impact of corrected sinus node recovery time in predicting recurrence in patients with paroxysmal atrial fibrillation.

J Int Med Res 2021 May;49(5):3000605211010103

Department of Cardiology, Tongji Hospital Affiliated to 12476Tongji University, Shanghai, China.

Objective: Atrial fibrillation (AF) and sinus node dysfunction (SND) have common underlying pathophysiological mechanisms. As an index of SND, corrected sinus node recovery time (CSNRT) may also reflect atrial function. The aim of the present study was to determine whether CSNRT predicts AF recurrence in patients undergoing AF ablation. Read More

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Effect of Continuous Positive Airway Pressure on Arrhythmia in Atrial Fibrillation and Sleep Apnea: A Randomized Controlled Trial.

Am J Respir Crit Care Med 2021 May 3. Epub 2021 May 3.

Oslo University Hospital, 155272, Oslo, Norway.

Rationale: Sleep apnea (SA) is highly prevalent in patients with atrial fibrillation (AF), and both conditions are associated with adverse cardiovascular outcomes.

Objectives: To determine the effect of continuous positive airway pressure (CPAP) on AF burden.

Methods: This open-label, parallel-group, randomized, controlled trial included patients with paroxysmal AF and moderate-to-severe SA (apnea-hypopnea index ≥15). Read More

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Plasma Galectin-3 is associated with progression from paroxysmal to persistent atrial fibrillation.

BMC Cardiovasc Disord 2021 May 2;21(1):226. Epub 2021 May 2.

Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, China.

Background: Galectin-3 (Gal-3) is currently recognized as a promising biomarker for myocardial fibrosis. This study aimed to explore the potential association between plasma Gal-3 concentrations and atrial fibrillation (AF) progression in paroxysmal AF (PAF) patients METHODS: A total of 213 PAF patients were included for analysis in this study. All peripheral blood samples were prospectively collected and stored at -80℃ for subsequent Gal-3 quantification. Read More

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Pulsed Field Ablation of Paroxysmal Atrial Fibrillation: 1-Year Outcomes of IMPULSE, PEFCAT, and PEFCAT II.

JACC Clin Electrophysiol 2021 Apr 22. Epub 2021 Apr 22.

IHU LIRYC ANR-10-IAHU-04, Centre Hospitalier Universitaire Bordeaux, Bordeaux University, Bordeaux, France.

Objective: This study sought to determine whether durable pulmonary vein isolation (PVI) using pulsed field ablation (PFA) translates to freedom from atrial fibrillation recurrence without an increase in adverse events.

Background: PFA is a nonthermal ablative modality that, in preclinical studies, is able to preferentially ablate myocardial tissue with minimal effect on surrounding tissues. Herein, we present 1-year clinical outcomes of PFA. Read More

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Long-Term Outcomes of Near-Zero Radiation Ablation of Paroxysmal Supraventricular Tachycardia: A Comparison With Fluoroscopy-Guided Approach.

JACC Clin Electrophysiol 2021 Apr 21. Epub 2021 Apr 21.

Cardiology and Arrhythmology Clinic, University Hospital "Umberto I-Lancisi-Salesi," Marche Polytechnic University, Ancona, Italy; Department of Clinical, Special and Dental Sciences, University Hospital "Umberto I-Lancisi-Salesi," Marche Polytechnic University, Ancona, Italy.

Objectives: This study aimed to assess the long-term outcomes of minimally fluoroscopic approach (MFA) compared with conventional fluoroscopic ablation (ConvA) in terms of recurrences of arrhythmia and long-term complications.

Background: Catheter ablation (CA) of supraventricular tachycardia (SVT) with an MFA, under the guidance of electroanatomic mapping (EAM) systems, results in a significant reduction in exposure to ionizing radiations without impairing acute procedural success and complication rate. However, data regarding long-term outcomes of MFA compared with ConvA are lacking. Read More

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Catheter ablation of atrial fibrillation in patients with hypertrophic cardiomyopathy: a European observational multicentre study.

Europace 2021 Apr 30. Epub 2021 Apr 30.

Cardiac Electrophysiology Department, Barts Heart Centre, St. Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK.

Aims: Atrial fibrillation (AF) is common in hypertrophic cardiomyopathy (HCM). Data on the efficacy of catheter ablation of AF in HCM patients are sparse.

Methods And Results: Observational multicentre study in 137 HCM patients (mean age 55. Read More

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Genetic updates on paroxysmal dyskinesias.

J Neural Transm (Vienna) 2021 Apr 30;128(4):447-471. Epub 2021 Apr 30.

Center for Neurological Restoration, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.

The paroxysmal dyskinesias are a diverse group of genetic disorders that manifest as episodic movements, with specific triggers, attack frequency, and duration. With recent advances in genetic sequencing, the number of genetic variants associated with paroxysmal dyskinesia has dramatically increased, and it is now evident that there is significant genotype-phenotype overlap, reduced (or incomplete) penetrance, and phenotypic variability. In addition, a variety of genetic conditions can present with paroxysmal dyskinesia as the initial symptom. Read More

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Pulmonary vein stenosis after HotBalloon pulmonary vein isolation of paroxysmal atrial fibrillation.

Heart Vessels 2021 Apr 30. Epub 2021 Apr 30.

The Heart Rhythm Center, Tokyo Heart Center, 5-4-12 Kitashinagawa, Shinagawa-ku, Tokyo, 141-0001, Japan.

HotBalloon-based pulmonary vein isolation (HBPVI) has yielded encouraging clinical results in the treatment of paroxysmal atrial fibrillation (PAF). However, pulmonary vein (PV) stenosis remains a concern. The influence of longer application duration on PV stenosis has not yet been systematically evaluated. Read More

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Behavior of AV synchrony pacing mode in a leadless pacemaker during variable AV conduction and arrhythmias.

J Cardiovasc Electrophysiol 2021 Apr 29. Epub 2021 Apr 29.

Kepler University Hospital, Medical Faculty, Johannes Kepler University, Linz, Austria.

Introduction: MARVEL 2 assessed the efficacy of mechanical atrial sensing by a ventricular leadless pacemaker, enabling a VDD pacing mode. The behavior of the enhanced MARVEL 2 algorithm during variable atrio-ventricular conduction (AVC) and/or arrhythmias has not been characterized and is the focus of this study.

Methods: Of the 75 patients enrolled in the MARVEL 2 study, 73 had a rhythm assessment and were included in the analysis. Read More

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Towards Mutation-Specific Precision Medicine in Atypical Clinical Phenotypes of Inherited Arrhythmia Syndromes.

Int J Mol Sci 2021 Apr 10;22(8). Epub 2021 Apr 10.

Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi 371-8511, Gunma, Japan.

Most causal genes for inherited arrhythmia syndromes (IASs) encode cardiac ion channel-related proteins. Genotype-phenotype studies and functional analyses of mutant genes, using heterologous expression systems and animal models, have revealed the pathophysiology of IASs and enabled, in part, the establishment of causal gene-specific precision medicine. Additionally, the utilization of induced pluripotent stem cell (iPSC) technology have provided further insights into the pathophysiology of IASs and novel promising therapeutic strategies, especially in long QT syndrome. Read More

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Thrombotic Complications in Patients with Immune-Mediated Hemolysis.

J Clin Med 2021 Apr 18;10(8). Epub 2021 Apr 18.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Autoimmune hemolytic anemias are rare and heterogeneous disorders characterized by hemolysis, which is a well-recognized risk factor for thrombosis. The most common immune-mediated anemias are represented by autoimmune hemolytic anemia and paroxysmal nocturnal hemoglobinuria, both associated with a high rate of thrombosis. Multiple pathophysiological mechanisms for thrombosis have been proposed, involving hemolysis itself and additional effects of the immune system. Read More

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A Systematic Review on the Correlations between Left Atrial Strain and Cardiovascular Outcomes in Chronic Kidney Disease Patients.

Diagnostics (Basel) 2021 Apr 8;11(4). Epub 2021 Apr 8.

Nephrology Clinic, Dialysis, and Renal Transplant Center-'C.I. Parhon' University Hospital, 700503 Iasi, Romania.

Left atrial strain (LASr) represents a relatively new but promising technique for left atrial and left ventricle function evaluation. LASr was strongly linked to myocardial fibrosis and endocardial thickness, suggesting the utility of LASr in subclinical cardiac dysfunction detection. As CKD negatively impacts cardiovascular risk and mortality, underlying structural and functional abnormalities of cardiac remodeling are widely investigated. Read More

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Optimizing indices of AF susceptibility and burden to evaluate AF severity, risk and outcomes.

Cardiovasc Res 2021 Apr 26. Epub 2021 Apr 26.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom.

Atrial fibrillation (AF) has heterogeneous patterns of presentation concerning symptoms, duration of episodes, AF burden, and the tendency to progress towards the terminal step of permanent AF. AF is associated with a risk of stroke/thromboembolism traditionally considered dependent on patient-level risk factors rather than AF type, AF burden or other characterizations. However, the time spent in AF appears related to an incremental risk of stroke, as suggested by the higher risk of stroke in patients with clinical AF versus subclinical episodes and in patients with non-paroxysmal AF versus paroxysmal AF. Read More

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[The preliminary value of vector flow mapping on assessment of left intraventricular pressure difference in patients with paroxysmal atrial fibrillation].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2021 Apr;38(2):310-316

Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, P.R.China.

This study aims to explore the intraventricular pressure difference (IVPD) within left ventricle in patients with paroxysmal atrial fibrillation (PAF) by using the relative pressure imaging (RPI) of vector flow mapping (VFM). Twenty patients with paroxysmal atrial fibrillation (PAF) and thirty control subjects were enrolled in the study. Systolic and diastolic IVPD derived from VFM within left ventricle and conventional echocardiographic parameters were analyzed. Read More

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Total atrial conduction time as a possible predictor of atrial fibrillation recurrence after catheter ablation for paroxysmal atrial fibrillation: relationship between electrical atrial remodeling and structural atrial remodeling time courses.

J Med Ultrason (2001) 2021 Apr 28. Epub 2021 Apr 28.

Division of Clinical Laboratory, Kagoshima University Hospital, Kagoshima, Japan.

Purpose: Recently, the estimated total atrial conduction time measured using tissue Doppler imaging (PA-TDI duration) has been reported as a more accurate predictor of atrial fibrillation (AF) recurrence after catheter ablation than left atrial volume index (LAVI). The PA-TDI duration is considered to reflect electrical and structural remodeling in the right atrium (RA) and left atrium (LA). We sought to investigate the association between AF recurrence and PA-TDI duration after AF ablation. Read More

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Paroxysmal Sympathetic Hyperactivity in Severe Anti-N-Methyl-d-Aspartate Receptor Encephalitis: A Single Center Retrospective Observational Study.

Front Immunol 2021 12;12:665183. Epub 2021 Apr 12.

Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Paroxysmal sympathetic hyperactivity (PSH) is a disorder with excessive sympathetic activity commonly recognized in patients with acquired brain injury. Autonomic instability is frequent in anti-N-methyl-d-aspartate receptor encephalitis (anti-NMDARE). However, PSH in anti-NMDARE has gained little attention. Read More

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Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp.

Front Pharmacol 2021 12;12:649414. Epub 2021 Apr 12.

Department of Medical Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Consequently, novel therapies are being developed. Ultimately, the impact of compounds on the action potential (AP) needs to be tested in freshly isolated human atrial myocytes. Read More

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