Retina 2021 Jul 16. Epub 2021 Jul 16.
Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany Department of Ophthalmology, Leiden University Medical Center, Leiden, Netherlands Department of Medicine, Division of Endocrinology, and Center for Endocrine Tumors, Leiden University Medical Center, Leiden, Netherlands Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany Department of Ophthalmology, Academic Medical Center, Amsterdam, the Netherlands F. Hoffmann-La Roche, 4070 Basel, Switzerland.
Purpose: To investigate and compare the salivary alpha amylase (sAA) activity as an indicator of the sympathetic activity and stress response in patients with central serous chorioretinopathy (CSC) and healthy controls.
Methods: Prospective, multi-center case series including 80 CSC patients and 88 healthy controls. CSC status was classified as either active or inactive, depending on the presence of subretinal fluid on optical coherence tomography (OCT). Read More