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Fully Automated Artery-Specific Calcium Scoring Based on Machine Learning in Low-Dose Computed Tomography Screening.

Rofo 2022 Jan 26. Epub 2022 Jan 26.

Department for Diagnostic and Interventional Radiology, Eberhard Karls Universitat Tubingen, Tuebingen, Germany.

Purpose:  Evaluation of machine learning-based fully automated artery-specific coronary artery calcium (CAC) scoring software, using semi-automated software as a reference.

Methods:  A total of 505 patients underwent non-contrast-enhanced calcium scoring computed tomography (CSCT). Automated, machine learning-based software quantified the Agatston score (AS), volume score (VS), and mass score (MS) of each coronary artery [right coronary artery (RCA), left main (LM), circumflex (CX) and left anterior descending (LAD)]. Read More

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January 2022

Abnormal white matter structure in hoarding disorder.

J Psychiatr Res 2022 Jan 18;148:1-8. Epub 2022 Jan 18.

Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Japan, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address:

Although preliminary neuroimaging research suggests that patients with hoarding disorder (HD) show widespread abnormal task-related activity in the brain, there has been no research on alterations in the white matter tracts in these patients. The aim of this study was to investigate the characteristics of the major white matter tracts in patients with HD. Tract-based spatial statistics were used to search for white matter tract abnormalities throughout the brain in 25 patients with HD and 36 healthy controls. Read More

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January 2022

Lens epithelial cell removal in routine phacoemulsification: is it worth the bother?

Am J Ophthalmol 2022 Jan 23. Epub 2022 Jan 23.

Department of Ophthalmology, University of New South Wales at Prince of Wales Hospital, Sydney, Australia; Capital Health System, New Jersey Surgery Centre, United States of America.

Purpose: To review the literature on crystalline lens epithelial cell (LEC) removal in routine phacoemulsification and determine whether it should be incorporated as part of a surgeon's standard technique.

Design: Perspective.

Methods: Expert commentary with video demonstrations on techniques of removal of LEC's and associated potential complications. Read More

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January 2022

Comparison of reprojected bone SPECT/CT and planar bone scintigraphy for the detection of bone metastases in breast and prostate cancer.

Nucl Med Commun 2022 Jan 25. Epub 2022 Jan 25.

Department of Clinical Physiology, Nuclear Medicine and Turku PET Centre, Turku University Hospital and University of Turku, Turku, Clinical Physiology and Nuclear Medicine, Helsinki University Hospital, Helsinki, Department of Clinical Physiology and Nuclear Medicine, Hospital Nova of Central Finland, Jyväskylä, Department of Urology, Department of Diagnostic Radiology, Turku University Hospital and University of Turku, Turku, Finland, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA, Department of Oncology and Radiotherapy, Department of Biostatistics, University of Turku, Turku, Finland HERMES Medical Solutions, Strandbergsgatan 16, Stockholm, Sweden Laboratory of Clinical Physiology and Nuclear Medicine, Päijät-Häme Central Hospital, Lahti and Department of Medical Physics, Turku University Hospital, Turku, Finland.

Objective: The aim of this study was to compare reprojected bone SPECT/CT (RBS) against planar bone scintigraphy (BS) in the detection of bone metastases in breast and prostate cancer patients.

Methods: Twenty-six breast and 105 prostate cancer patients with high risk for bone metastases underwent 99mTc-HMDP BS and whole-body SPECT/CT, 1.5-T whole-body diffusion-weighted MRI and 18F-NaF or 18F-PSMA-1007 PET/CT within two prospective clinical trials (NCT01339780 and NCT03537391). Read More

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January 2022

Imaging Follow-up of Pediatric Transphyseal Anterior Cruciate Ligament Reconstruction: A Case Report.

JBJS Case Connect 2022 Jan 26;12(1). Epub 2022 Jan 26.

Department of Orthopaedic Surgery, Hôpital des Enfants, CHU de Toulouse, France.

Case: We are reporting on the x-ray and magnetic resonance imaging (MRI) follow-up of an 8-year-old boy who underwent transphyseal anterior cruciate ligament reconstruction with a 4-strand semitendinosus tendon graft. His graft was followed for 5 years by MRI, demonstrating a satisfactory but slow and gradual ligamentization process.

Conclusion: The long-term MRI follow-up demonstrated the satisfactory outcome of the transphyseal reconstruction, although with a slower and more progressive ligamentization process than in adult patients. Read More

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January 2022

[Surgical treatment of obstructive hypertrophic cardiomyopathy combined with muscle bridging of the left anterior descending artery].

Khirurgiia (Mosk) 2022 (1):81-83

Petrovsky National Scientific Center of Surgery, Moscow, Russia.

Myocardial bridging is often detected during diagnostic coronary angiography in patients with congenital and acquired heart defects. In most cases, muscle bridging does not require surgical treatment. Myocardial bridging and tunnels causing compression of one or more major coronary arteries is a potential cause of myocardial ischemia in patients with hypertrophic cardiomyopathy. Read More

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January 2022

[Transanal endoscopic rectal resection: immediate and long-term results].

Khirurgiia (Mosk) 2022 (1):30-38

National Medical Research Center for Oncology, Rostov-on-Don, Russia.

Objective: To analyze the results of transanal endoscopic microsurgery in patients with rectal tumors.

Material And Methods: We analyzed 87 transanal endoscopic resections of rectal benign tumors (35 patients) and rectal cancer cT1N0M0 (52 patients) for the period since 2012.

Results: There were 2 (3. Read More

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January 2022

Preliminary Evaluation of a Novel Body-Weight Supported Postural Perturbation Module for Gait and Balance Rehabilitation after Stroke.

JMIR Rehabil Assist Technol 2022 Jan 26. Epub 2022 Jan 26.

Frank H Netter MD School of Medicine, Quinnipiac University, North Haven, US.

Background: Impaired balance-regulation after stroke put patients and therapists at risk for injury during rehabilitation. Body-weight-support systems (BWSSs) minimize this risk and allow patients to safely practice balance activities during therapy. Treadmill based balance perturbation systems with BWSSs are known to improve balance in patients with age or disease related impairments. Read More

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January 2022

Allergic rhinitis, microbiota and passive smoke in children: A pilot study.

Pediatr Allergy Immunol 2022 Jan;33 Suppl 27:22-26

Department of Maternal Infantile and Urological Sciences, Division of Pediatric Allergology and Immunology, Sapienza University of Rome, Rome, Italy.

Background: Allergic rhinitis (AR) is one of the most common allergic diseases affecting children. Objective assessment of nasal obstruction is possible through active anterior rhinomanometry (AAR). Several factors, such as passive smoke exposure (PSE), are triggers for worsening nasal obstruction and chronic inflammation. Read More

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January 2022

Fragmented QRS complex on a 12-lead electrocardiogram predicts cardiovascular and all-cause mortality in dialysis patients.

Semin Dial 2022 Jan 25. Epub 2022 Jan 25.

Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Tianjin, China.

Background: Cardiovascular disease (CVD) is the most common cause of mortality in end-stage renal disease (ESRD) patients. Fragmented QRS complex (fQRS) has been reported as a helpful marker in evaluating various cardiovascular pathologies. We aimed to investigate the value of the fQRS complex clinical decision of ESRD patients receiving dialysis. Read More

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January 2022

Nasolacrimal canal morphology with or without idiopathic obstruction in Caucasian adults: a multidetector CT study.

Int Ophthalmol 2022 Jan 26. Epub 2022 Jan 26.

Department of Radiology, Medical School, Uludag University, Bursa, Turkey.

Purpose: To compare the morphological features of the bony nasolacrimal canal (NLC) in Caucasian adults with and without primary acquired nasolacrimal duct obstruction (PANDO).

Methods: The study included one eye each from 38 patients with PANDO and 38 age- and gender-matched controls without PANDO, all of whom underwent multidetector computed tomography. In tomographic images, length, and orientation angles of the NLC, transverse canal diameters at the duct entrance and lower end, and minimum (narrowest) transverse and anterior-posterior canal diameters were measured. Read More

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January 2022

Resolution of coronary arteritis following tuberculosis treatment.

J Clin Tuberc Other Mycobact Dis 2022 Feb 19;26:100295. Epub 2022 Jan 19.

Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Coronary artery aneurysm (CAA) in an uncommon condition usually associated with atherosclerosis, but systemic vasculitides constitute important differential diagnoses. A less recognized cause of CAA, tuberculosis (TB) has also been noted to occur simultaneously in patients with such vascular abnormalities.

Case Report: A 60-year-old female presented to the Emergency Department with a non-ST segment elevation myocardial infarction. Read More

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February 2022

Endovascular Mechanical Thrombectomy for Basilar Artery Occlusion Caused by Thrombosis as an Initial Manifestation of Acute Myelogenous Leukemia: A Case Report.

NMC Case Rep J 2021 2;8(1):767-772. Epub 2021 Nov 2.

Department of Neurosurgery, Japan Community Health Care Organization Kobe Central Hospital, Kobe, Hyogo, Japan.

We report a rare case of a basilar artery occlusion (BAO) caused by thrombosis as an initial magnification of acute myelogenous leukemia (AML) and performed mechanical thrombectomy (MT) to treat it. A 67-year-old female presented left hemiparalysis of her arm and right-sided blindness. Magnetic resonance imaging (MRI) and magnetic resonance angiography revealed acute infarction in the left occipital and anterior lobes of the cerebellum and incomplete BAO. Read More

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November 2021

Aneurysms Arising from Persistent Arteries in the Vertebrobasilar Paramedian Longitudinal Axis: Two Case Reports.

NMC Case Rep J 2021 7;8(1):665-671. Epub 2021 Oct 7.

Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.

A 50-year-old man and a 69-year-old woman with consciousness disturbance were diagnosed to have suffered from subarachnoid hemorrhage (SAH) involving the posterior fossa. In both cases, the initial 3D CT angiogram failed to reveal the SAH source in the vertebrobasilar system. Delayed 3D rotational angiography revealed aneurysms on unfamiliar aberrant arteries. Read More

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October 2021

Cerebral Hyperperfusion and Concomitant Reversible Lesion at the Splenium after Direct Revascularization Surgery for Adult Moyamoya Disease: Possible Involvement of MERS and Watershed Shift Phenomenon.

NMC Case Rep J 2021 6;8(1):451-456. Epub 2021 Aug 6.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

Superficial temporal artery (STA)-middle cerebral artery (MCA) bypass is the standard surgical treatment for moyamoya disease (MMD). Local cerebral hyperperfusion (CHP) is one of the potential complications, which could enhance intrinsic inflammation and oxidative stress in MMD patients and accompany concomitant watershed shift (WS) phenomenon, defined as the paradoxical decrease in the cerebral blood flow (CBF) near the site of CHP. However, CHP and simultaneous remote reversible lesion at the splenium have never been reported. Read More

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Surgical Treatment for Mesial Temporal Lobe Epilepsy Accompanied with Neuro-Behçet's Disease: A Case Report.

NMC Case Rep J 2021 7;8(1):405-411. Epub 2021 Aug 7.

Department of Neurosurgery, Graduate School of Medicine, Kagoshima University, Kagoshima, Kagoshima, Japan.

Behçet's disease (BD) is a rare chronic inflammatory disease associated with systemic vasculitis. Involvement of the nervous system in BD is called neuro-BD (NBD). Epilepsy related to NBD is uncommon but responds well to anti-epileptic drugs. Read More

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Transient Global Amnesia Following Coil Embolization for a Basilar-tip Aneurysm: Case Reports of Two Patients.

NMC Case Rep J 2021 29;8(1):113-116. Epub 2021 Apr 29.

Department of Neurosurgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

Transient global amnesia (TGA) can be caused by medications, ischemia, metabolic abnormalities, and seizures. We describe two cases of TGA following coil embolization for a basilar-tip aneurysm. A 73-year-old woman developed transient acute anterograde amnesia after coil embolization for a basilar-tip aneurysm. Read More

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Coronary artery aneurysms of unknown origin in a 14-year-old girl.

J Cardiol Cases 2022 Feb 17;25(2):106-109. Epub 2021 Aug 17.

Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shinmachi, Osaka, Suita-shi 564-8565, Japan.

The case of a 14-year-old girl with acute myocardial infarction due to coronary artery aneurysms (CAAs) of unknown origin, which resembled coronary artery lesions caused by Kawasaki disease, is reported. She was transferred to our hospital due to chest pain with ST-T elevation. She had no history of Kawasaki disease. Read More

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February 2022

A Case Report: Directional coronary atherectomy supported with optical coherence tomography is useful for the slit lesion.

J Cardiol Cases 2022 Feb 30;25(2):91-94. Epub 2021 Jul 30.

Department of Cardiology, Toyohashi Heart Center, Aichi, Japan.

Background: Directional coronary atherectomy (DCA) was revived in Japan in 2014. DCA is a special procedure to remove the atherosclerotic plaque of coronary artery during percutaneous coronary intervention. We present the case of a 91-year-old woman with symptoms of angina. Read More

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February 2022

Swallowing kinematic analysis might be helpful in predicting aspiration and pyriform sinus stasis.

Sci Rep 2022 Jan 25;12(1):1354. Epub 2022 Jan 25.

Department of Physical Medicine and Rehabilitation, College of Medicine, National Taiwan University, Taipei, Taiwan.

Aspiration due to dysphagia can lead to aspiration, which negatively impacts a patient's overall prognosis. Clinically, videofluoroscopic swallow study (VFSS) is considered the gold-standard instrument to determine physiological impairments of swallowing. According to previously published literature, kinematic analyses of VFSS might provide further information regarding aspiration detection. Read More

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January 2022

Assessment of fluid unresponsiveness guided by lung ultrasound in abdominal surgery: a prospective cohort study.

Sci Rep 2022 Jan 25;12(1):1350. Epub 2022 Jan 25.

Centre Hospitalier Universitaire Amiens-Picardie, Rond-Point du professeur Christian Cabrol, 80000, Amiens, France.

A fluid challenge can generate an infraclinical interstitial syndrome that may be detected by the appearance of B-lines by lung ultrasound. Our objective was to evaluate the appearance of B-lines as a diagnostic marker of preload unresponsiveness and postoperative complications in the operating theater. We conducted a prospective, bicentric, observational study. Read More

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January 2022

Benefit and risk of intravenous alteplase in patients with acute large vessel occlusion stroke and low ASPECTS.

J Neurointerv Surg 2022 Jan 25. Epub 2022 Jan 25.

Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: The benefit of best medical treatment including intravenous alteplase (IVT) before mechanical thrombectomy (MT) in patients with acute ischemic stroke and extensive early ischemic changes on baseline CT remains uncertain. The purpose of this study was to evaluate the benefit of IVT for patients with low ASPECTS (Alberta Stroke Programme Early CT Score) compared with patients with or without MT.

Methods: This multicenter study pooled consecutive patients with anterior circulation acute stroke and ASPECTS≤5 to analyze the impact of IVT on functional outcome, and to compare bridging IVT with direct MT. Read More

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January 2022

Safety and Neurologic Recovery of L2 Nerve Root Sacrificed in Total En Bloc Spondylectomy Involving the L2 Vertebra.

Int J Spine Surg 2021 Dec;15(6):1205-1210

Department of Orthopaedic Surgery Graduate School of Medical Sciences, Kanazawa University, Japan.

Background: The L2 nerve root is considered part of the lumbar plexus that innervates the iliopsoas (IP) and quadricep muscles (Qd). Total en bloc spondylectomy (TES) at the L2 vertebra requires bilateral nerve root transection to facilitate surgical dissection and vertebral body removal. Information regarding neurological function recovery of the IP and Qd in patients with muscle weakness before TES is lacking. Read More

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December 2021

Poorer Preoperative Function Leads to Delayed Return to Work After Anterior Cervical Discectomy and Fusion for Degenerative Cervical Myelopathy.

Int J Spine Surg 2021 Dec;15(6):1172-1179

Department of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.

Background: The factors that affect return to work (RTW) after anterior cervical discectomy and fusion (ACDF) for degenerative cervical myelopathy (DCM) remain unclear, especially in a non-Workers' Compensation setting. We aimed to (1) identify factors that influence RTW in patients undergoing ACDF (2) determine if early RTW plays a role in functional outcomes, quality of life, and satisfaction.

Methods: Prospectively collected data of 103 working adults who underwent primary ACDF for DCM were retrospectively reviewed. Read More

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December 2021

Current Concepts of Cervical Disc Arthroplasty.

Int J Spine Surg 2021 Dec;15(6):1162-1171

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Background: Radiculopathy and myelopathy resulting from degenerative disc disease are currently treated with anterior cervical discectomy and fusion (ACDF), but there is a high incidence of adjacent segment disease after treatment.

Methods: With recent advances in cervical disc arthroplasty (CDA), we performed a review of published articles, examining the latest clinical data on the efficacy, safety, and complications of the current cervical disc devices on the market. We focused on the long-term follow up data of single-level, multi-level, and hybrid CDA as compared to ACDF, paying close attention to the newest cervical disc devices. Read More

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December 2021

Management of Symptomatic Cervical Spine Pseudarthrosis: A Suggested Algorithm for Surgical Planning.

Int J Spine Surg 2021 Dec;15(6):1155-1161

Department of Spine Surgery, Zentralklinik Bad Berka, Germany.

Background: The clinical outcome of anterior cervical decompression and fusion (ACDF) correlates with fusion rates. There is a debate about how patients with symptomatic pseudarthrosis should be managed. In this study, a treatment plan is developed based on the surgical results of 95 patients and the recent literature. Read More

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December 2021

Does Cervical Spondylolisthesis Influence Patient-Reported Outcomes After Anterior Cervical Discectomy and Fusion Surgery?

Int J Spine Surg 2021 Dec;15(6):1149-1154

Department of Orthopaedic Surgery, Rothman Orthopaedic Institute, 925 Chestnut St., Philadelphia, PA, USA.

Background: No prior work has explored whether the presence of degenerative spondylolisthesis impacts patient-reported outcome measurements (PROMs) after an anterior cervical discectomy and fusion (ACDF); therefore, the goal of the current study was to determine whether the presence of a spondylolisthesis affects PROMs after an ACDF.

Methods: A retrospective cohort study was conducted on patients over the age of 18 who underwent a 1- or 2-level ACDF. All patients received preoperative standing lateral x-rays and were placed into 1 of 2 groups based on the presence of cervical spondylolisthesis from C2-T1: (1) no spondylolisthesis (NS) group or (2) spondylolisthesis (S) group. Read More

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December 2021

Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin's Triangle: A Case Series With Initial Clinical and Radiographic Results.

Int J Spine Surg 2021 Dec;15(6):1121-1129

Department of Neurosurgery, Division of Spine, Duke University Medical Center, Durham, North Carolina, 27701, USA

Background: There has been an increased interest in lumbar interbody fusions through Kambin's triangle. In this study, we describe percutaneous access to the lumbar disc and insertion of an expandable titanium cage through Kambin's triangle without facetectomy. The objective of this study is to determine the feasibility as well as clinical and radiographical outcomes of completely percutaneous lumbar interbody fusion (percLIF) using an expandable titanium cage through Kambin's triangle. Read More

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December 2021

Recovery of Physical Function Based on Body Mass Index Following Anterior Cervical Discectomy and Fusion.

Int J Spine Surg 2021 Dec;15(6):1111-1120

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA

Background: Body mass index (BMI) serves as a risk factor for complications and poorer outcomes following anterior cervical discectomy and fusion (ACDF). This study investigates the association between BMI and Patient Reported Outcomes Measurement Information System physical function (PROMIS-PF) following ACDF.

Methods: A prospectively maintained surgical registry was retrospectively reviewed for cervical spine surgeries between 2015 and 2019. Read More

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December 2021

Indirect Decompression for the Treatment of Degenerative Lumbar Stenosis.

Int J Spine Surg 2021 Dec;15(6):1066-1071

Center for Disc Replacement at Texas Back Institute, Plano, Texas, USA.

Background: Surgical treatment of symptomatic lumbar stenosis has traditionally included laminectomy for direct decompression. With increasing options for lumbar interbody fusion, there has been growing interest in indirect decompression to treat degenerative stenosis. The primary purpose of this study was to determine whether indirect decompression via anterior lumbar interbody fusion (ALIF) can provide symptomatic relief in patients with lumbar spinal stenosis. Read More

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December 2021