12,193 results match your criteria patient-reported pain

Does Loss of Spondylolisthesis Reduction Impact Clinical and Radiographic Outcomes after Minimally Invasive Transforaminal Lumbar Interbody Fusion.

Spine J 2021 Jun 9. Epub 2021 Jun 9.

Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA; Weill Cornell Medical College, 1300 York Ave, New York, NY, 10065, USA. Electronic address:

Background Context: Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) is a common operative approach to address degenerative lumbar stenosis and spondylolisthesis which has failed nonoperative care. Compared to open TLIF, MI-TLIF relies to a greater extent on indirect decompression resulting in a heightened awareness of spondylolisthesis reduction among MI surgeons. To what extent intraoperative reduction is achieved as well as the rate and clinical impact of loss or reduction and slip recurrence remain unknown. Read More

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Using Item Response Theory to Identify Responders to Treatment: Examples with the Patient-Reported Outcomes Measurement Information System (PROMIS®) Physical Function Scale and Emotional Distress Composite.

Psychometrika 2021 Jun 12. Epub 2021 Jun 12.

Department of psychology, UCLA, Los Angeles, CA, 90095-1563, USA.

The reliable change index has been used to evaluate the significance of individual change in health-related quality of life. We estimate reliable change for two measures (physical function and emotional distress) in the Patient-Reported Outcomes Measurement Information System (PROMIS®) 29-item health-related quality of life measure (PROMIS-29 v2.1). Read More

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Image-guided intervention in the management of chronic patellar tendinopathy with calcification: a three-pronged approach.

BMJ Case Rep 2021 Jun 11;14(6). Epub 2021 Jun 11.

Radiology, London North West University Healthcare NHS Trust, London, UK.

Patellar tendinopathy is a common cause of knee pain and functional impairment in athletes. It is commonly managed using conservative measures such as physiotherapy, but cases that are refractory to such treatment may require a more invasive approach. Various forms of image-guided injection therapy have been described in the literature. Read More

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Autologous Matrix-Induced Chondrogenesis (AMIC) for Isolated Retropatellar Cartilage Lesions: Outcome after a Follow-Up of Minimum 2 Years.

Cartilage 2021 Jun 11:19476035211021908. Epub 2021 Jun 11.

Department of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.

Purpose: To evaluate autologous matrix-induced chondrogenesis (AMIC) for isolated focal retropatellar cartilage lesions and the influence of patellofemoral (PF) anatomy on clinical outcomes at a minimum of 2-year follow-up.

Methods: Twenty-nine consecutive patients (31 knees) who underwent retropatellar AMIC with a mean age of 27.9 ± 11. Read More

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Radiographic severity, extent and pattern of cartilage loss are not associated with patient reported outcomes before or after total knee arthroplasty in end-stage knee osteoarthritis.

Knee 2021 Jun 8;31:54-63. Epub 2021 Jun 8.

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, United Kingdom.

Background: The aim of this study was to determine if radiographic severity, extent or pattern of knee osteoarthritis was associated with pain and function before total knee arthroplasty (TKA) or improvement therein one year after TKA.

Methods: A prospective study of 259 patients undergoing unilateral TKA for Kellgren-Lawrence (KL) grade ≥ 3 knee osteoarthritis was conducted: mean age 69.8 ± 9. Read More

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Composite psychosocial risk based on the fear avoidance model in patients undergoing anterior cruciate ligament reconstruction: Cluster-based analysis.

Phys Ther Sport 2021 Jun 2;50:217-225. Epub 2021 Jun 2.

Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Center for Musculoskeletal Research, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Physical Medicine and Rehabilitation, Osher Center for Integrative Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

Objectives: To examine associations between preoperative fear-avoidance model (FAM) risk subgroup status and patient expectation of surgical success with postoperative outcomes at 6 and 12 months after anterior cruciate ligament reconstruction (ACLR).

Design: Cohort study.

Setting: Academic medical center. Read More

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Prospective, Randomized, Double-Blinded Clinical Trial Comparing PEEK and Allograft Spacers in Patients Undergoing Transforaminal Lumbar Interbody Fusion Surgeries.

Spine J 2021 Jun 8. Epub 2021 Jun 8.

Boulder Neurosurgical Associates, Boulder, Colorado, USA; Justin Parker Neurological Institute, Boulder, Colorado, USA. Electronic address:

Background Context: Allograft and polyether-ether-ketone (PEEK) radiographic, biomechanical, histological properties have been extensively studied and both spacers have their advantages and shortcomings. There are no comparative randomized or double-blinded spinal fusion clinical trials reported to date.

Purpose: The study's primary objective was to prospectively investigate clinical and radiological outcomes in patients undergoing lumbar interbody fusions and randomized to receive either PEEK or structural bone allografts. Read More

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Understanding the patient experience in hepatocellular carcinoma: a qualitative patient interview study.

Qual Life Res 2021 Jun 11. Epub 2021 Jun 11.

AstraZeneca, 1 Medimmune Way, Gaithersburg, MD, 20878, USA.

Purpose: This study aimed to elucidate the patient experience of hepatocellular carcinoma (HCC) to guide patient-centered outcome measurement in drug development.

Methods: Patients with HCC participated in qualitative interviews to elicit disease-related signs/symptoms and impacts, using discussion guides developed from literature searches and discussions with oncologists. Interview participants rated the disturbance of their experiences (0-10 scale). Read More

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In Orthopaedic Speciality Care, Longer Explanations Are Not More Caring or More Satisfying.

Clin Orthop Relat Res 2021 Jun 11. Epub 2021 Jun 11.

Department of Surgery and Perioperative Care, Dell Medical School, the University of Texas at Austin, Austin, TX, USA.

Background: Research consistently documents no correlation between the duration of a musculoskeletal specialty care visit and patient experience (perceived empathy of the specialist and satisfaction with care). Based on a combination of clinical experience and other lines of research, we speculate that longer visits are often related to discordance between specialist and patient interpretation of symptoms and weighting of available test and treatment options. If this is true, then the specific duration of time discussing the specialist's interpretations and options with the patient (expertise transfer) might correlate with satisfaction with care and perceived empathy of the clinician even if the total visit time does not. Read More

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Open vs closed surgical exposure of palatally displaced canines: a comparison of clinical and patient-reported outcomes-a multicentre, randomized controlled trial.

Eur J Orthod 2021 Jun 11. Epub 2021 Jun 11.

Postgraduate Dental Education Center, Department of Oral and Maxillofacial Radiology, Örebro, Sweden.

Objectives: To compare treatment time, patients' perceptions during orthodontic treatment, dental fear and side effects, between open and closed surgical exposures in patients with palatally displaced canines (PDCs).

Trial Design: Multicentre, randomized controlled trial, with random 1:1 allocation of two parallel groups.

Materials And Methods: One hundred and twenty patients from three different orthodontic centres were randomized into one of the two intervention arms, open or closed surgical exposure. Read More

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Osteopathic Manipulative Treatment of Herpes Zoster Ophthalmicus/Postherpetic Neuralgia.

Cureus 2021 May 8;13(5):e14906. Epub 2021 May 8.

Osteopathic Manipulative Medicine, Touro College of Osteopathic Medicine, New York, USA.

Herpes zoster (HZ) and herpes zoster ophthalmicus (HZO) are the result of reactivation of varicella-zoster virus (VZV) from a dormant condition. Although HZ symptoms typically subside after a few weeks, HZO and postherpetic neuralgia (PHN) can persist at least 90 days after the appearance of the HZ rash. Presently, there is no gold standard for a disease-modifying therapy for postherpetic neuralgia and the current treatment is focused on early intervention and management of symptoms and dermatological complications. Read More

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The Association Between Psychological Factors and Outcomes After Distal Radius Fracture.

J Hand Surg Am 2021 Jun 7. Epub 2021 Jun 7.

Department of Orthopaedics, Edinburgh Orthopaedic Trauma Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

Purpose: The aim of this study was to identify psychological factors associated with pain intensity and disability following distal radius fracture.

Methods: We prospectively followed 216 adult patients with distal radius fracture for 9 months. Demographics, injury and treatment details, and psychological measures (Hospital Anxiety and Depression Score [HADS], Pain Catastrophizing Scale, Posttraumatic Stress Disorder Checklist-Civilian, Tampa Scale for Kinesiophobia, Illness Perception Questionnaire Brief [IPQB], General Self-Efficacy Scale, and Recovery Locus of Control [RLOC]) were collected at enrollment. Read More

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Long-term Patient-Reported Outcome Measures Following Particulated Juvenile Allograft Cartilage Implantation for Treatment of Difficult Osteochondral Lesions of the Talus[Formula: see text].

Foot Ankle Int 2021 Jun 11:10711007211014173. Epub 2021 Jun 11.

Miami Orthopedics & Sports Medicine Institute, Coral Gables, FL, USA.

Background: Conventional methods are not suitable for difficult to treat osteochondral lesions of the talus (OCLTs). The role of particulated juvenile allograft articular cartilage implantation is not well elucidated for long-term patient outcomes.

Methods: Thirteen patients with difficult-to-treat OCLTs underwent arthroscopy-assisted implantation of particulated juvenile articular cartilage graft into defects from 2010 to 2012 by the same surgeon. Read More

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A Prospective Cohort Study Comparing Functional Outcomes of Primary and Revision Ankle Replacements.

Foot Ankle Int 2021 Jun 11:10711007211010188. Epub 2021 Jun 11.

Royal Devon and Exeter NHS Foundation Trust, Exeter, United Kingdom.

Background: The number of ankle and revision ankle replacements performed is increasing. There is limited research into functional outcomes, especially in revision ankle replacements. The primary aim of this cohort study was to determine the functional improvements following primary and revision ankle replacements and compare which gave the greatest improvement in functional scores. Read More

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Uterine Isthmus Agenesis with Inverted Uterine Body and Malrotated Kidney.

J Minim Invasive Gynecol 2021 Jun 7. Epub 2021 Jun 7.

The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA.

A 21-year-old with a history of cyclic abdominal pain beginning at age 13 and a prior diagnosis of a complex Mullerian anomaly represented with abdominal pain and a finding of a right distended hemi-uterus, left hematosalpinx, and cervix separate from the uterine body. After laparoscopic decompression for symptomatic relief at that time, she presented to our center for definitive mangament. After diagnostic vaginoscopy and laparoscopy confirmed the diagnosis of uterine isthmus agenesis, an abdominal approach to utero-cervical anastomosis was planned and undertaken. Read More

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Patient-Reported Outcomes and Risk of Hospitalization and Readmission in Patients with Inflammatory Bowel Diseases.

Dig Dis Sci 2021 Jun 10. Epub 2021 Jun 10.

Division of Gastroenterology, Department of Medicine, University of California San Diego, 9452 Medical Center Dr., ACTRI 1W501, La Jolla, CA, 92093, USA.

Background And Aims: Patient-reported outcome measures (PROMs) provide a wholesome view of patient well-being. We conducted a retrospective cohort study to evaluate whether PROMs inform risk of unplanned healthcare utilization in patients with IBD.

Methods: We identified adult patients with IBD who completed at least two surveys in a large Internet-based cohort within 1 year. Read More

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Patient-reported pain severity and health-related quality of life in patients with multiple myeloma in real world clinical practice.

Cancer Rep (Hoboken) 2021 Jun 10:e1429. Epub 2021 Jun 10.

Centre for Observational Research, Amgen Ltd, Uxbridge, UK.

Background: The association between patient self-reported pain severity and health-related quality-of-life (HRQoL) is poorly understood.

Aims: This real-world study of symptomatic multiple myeloma (MM) patients sought to determine how pain severity from a single question asked during routine clinical consultation was associated with HRQoL.

Methods And Results: Point-in-time data on HRQoL of 330 patients with MM (median age 70 years) receiving anti-myeloma therapy in Germany and Italy from November 2017 through February 2018 were analyzed. Read More

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Clinical and Patient-Reported Outcomes Following Peroneus Brevis Reconstruction With Hamstring Tendon Autograft.

Foot Ankle Int 2021 Jun 10:10711007211015186. Epub 2021 Jun 10.

Hospital for Special Surgery, New York, NY, USA.

Background: Peroneal tendon injuries are a common cause of lateral ankle pain and instability. While the use of hamstring autograft has been proposed as a viable surgical option for peroneus brevis reconstruction, reported outcomes with this technique are limited in the literature. We present patient-reported and clinical outcomes for patients who underwent peroneus brevis reconstruction with hamstring autograft. Read More

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The Impact of Coronal Plane Deformity on Ankle Arthrodesis and Arthroplasty.

Foot Ankle Int 2021 Jun 10:10711007211015185. Epub 2021 Jun 10.

University of Washington, Seattle, WA, USA.

Background: Ankle coronal plane deformity represents a complex 3-dimensional problem, and comparative data are lacking to guide treatment recommendations for optimal treatment of end-stage ankle arthritis with concomitant coronal plane deformity.

Methods: In total, 224 patients treated for end-stage ankle arthritis were enrolled in an observational trial. Of 112 patients followed more than 2 years, 48 patients (19 arthrodesis, 29 arthroplasty) had coronal plane deformity and were compared to 64 patients without coronal plane deformity (18 arthrodesis, 46 arthroplasty) defined as greater than 10 degrees of varus or valgus. Read More

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Scaphoid Excision and Bicolumnar Carpal Fusion with Retrograde Headless Screws.

J Wrist Surg 2021 Jun 20;10(3):201-207. Epub 2021 Jan 20.

The Ottawa Hospital - Civic Campus (J159), Ottawa, Ontario, Canada.

 Scaphoid excision and partial wrist fusion is used for the treatment of scapholunate advanced collapse/scaphoid nonunion advanced collapse wrist arthritis. The purpose of this study was to report midterm functional and radiographic outcomes in a series of patients who underwent bicolumnar fusion of the lunocapitate and triquetrohamate joints using retrograde headless screws.  Twenty-three consecutive patients (25 wrists) underwent surgery with this technique from January 2014 to May 2017 with a minimum follow-up of 1 year. Read More

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Impact of surgical site infection on patients' outcome after fixation of tibial plateau fractures: a retrospective multicenter study.

BMC Musculoskelet Disord 2021 Jun 9;22(1):531. Epub 2021 Jun 9.

Department of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany.

Background: Surgical site infection (SSI) occurs in 3-10 % of patients with surgically treated tibial plateau fractures. This study aimed to evaluate the impact of SSI on patients' outcome after fixation of tibial plateau fractures.

Methods: We conducted a retrospective multicenter study in seven participating level I trauma centers between January 2005 and December 2014. Read More

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Multicenter Retrospective Review of Safety and Efficacy of a Novel Minimally Invasive Lumbar Interspinous Fusion Device.

J Pain Res 2021 31;14:1525-1531. Epub 2021 May 31.

Center for Interventional Pain and Spine, Lancaster, PA, USA.

Introduction: Several treatment options exist for those with spinal stenosis, as well as degenerative changes. This series evaluates the use of an interspinous fixation (ISF) device as performed by interventional pain physicians.

Methods: This is a retrospective analysis identifying 32 patients with the diagnosis of lumbar degenerative disc disease with secondary diagnosis of lumbar spinal stenosis being treated with ISF with Aurora Spine Zip Interspinous Spacer. Read More

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Shockwave therapy associated with progressive exercises in rotator cuff tendinopathy: a clinical trial protocol.

Pain Manag 2021 Jun 9. Epub 2021 Jun 9.

Physioterapeutics Resources Laboratory, Department of Physical Therapy, Federal University of Sao Carlos (UFSCar), Rod. "Washington Luis, km 235, Sao Carlos", São Paulo, Brazil.

The aim of the present study is to determine whether adding shockwave therapy (SWT) to a progressive exercise program improves shoulder pain and function in individuals with rotator cuff tendinopathy (RC tendinopathy). Ninety patients diagnosed with rotator cuff tendinopathy will be randomly allocated into two groups: active SWT plus a progressive exercise program or placebo SWT plus a progressive exercise program. Primary outcomes will be measured using the Constant-Murley Score function questionnaire and by assessing patient-reported pain intensity with the numerical pain rating scale. Read More

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Effectiveness of Stratified Treatment for Back Pain in Danish Primary Care: A Randomised Controlled Trial.

Eur J Pain 2021 Jun 8. Epub 2021 Jun 8.

Department of Occupational Medicine, Regional Hospital West Jutland, University Research Clinic, Juelsminde, Denmark.

Background: A randomised controlled trial (RCT) of stratified care demonstrated superior clinical outcomes and cost-effectiveness for low back pain (LBP) patients in UK primary care. This is the first study in Europe, outside of the original UK study, to investigate the clinical efficacy and cost-effectiveness of stratified care compared with current practice for patients with non-specific LBP.

Methods: The study was a two-armed RCT. Read More

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Individual Participant Symptom Responses to Intra-Articular Lorecivivint in Knee Osteoarthritis: Post Hoc Analysis of a Phase 2B Trial.

Rheumatol Ther 2021 Jun 8. Epub 2021 Jun 8.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds, UK.

Introduction: Established thresholds for patient-reported outcomes (PROs) provide clinically relevant responder data from trials. Lorecivivint (LOR) is an intra-articular (IA) therapy in development for knee osteoarthritis (OA). A post hoc analysis from a phase 2b trial (NCT03122860) determined proportions of LOR responders. Read More

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Autologous semitendinosus tendon graft could function as a meniscal transplant.

Knee Surg Sports Traumatol Arthrosc 2021 Jun 8. Epub 2021 Jun 8.

Södersjukhuset/KISÖS, Stockholm, Sweden.

Purpose: Meniscectomy results in poor knee function and increased risk for osteoarthritis. Meniscal allograft transplantation is not widely used due to costs and availability. The semitendinosus tendon (ST) has the potential to remodel and revascularize in an intraarticular environment, such as ACL reconstruction. Read More

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Predictors of postoperative pain using PROMIS pain interference two-years following knee surgery.

J Orthop 2021 May-Jun;25:271-277. Epub 2021 May 18.

Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD, USA.

Introduction: The purpose of this study was to identify preoperative factors associated with worse PROMIS Pain Interference (PI) two years following knee surgery.

Methods: Participants completed surveys preoperatively and two years postoperatively. Data collected included demographics, medical history, and multiple patient-reported outcomes measures, including PROMIS PI. Read More

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Long-term Outcomes After Anal Fistula Surgery: Results From Two University Hospitals in Thailand.

Ann Coloproctol 2021 Jun 7. Epub 2021 Jun 7.

Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Purpose: This study aimed to evaluate long-term outcomes after anal fistula surgery from university hospitals in Thailand.

Methods: A prospectively collected database of patients with cryptoglandular anal fistula undergoing surgery from 2011 to 2017 in 2 university hospitals was reviewed. Outcomes were treatment failure (persistent or recurrent fistula), fecal continence status, and chronic postsurgical pain. Read More

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Defining Clinically Significant Improvement on the Patient-Reported Outcomes Measurement Information System Test at 1-Year Follow-up for Patients Undergoing Hip Arthroscopy for the Treatment of Femoroacetabular Impingement Syndrome.

Am J Sports Med 2021 Jun 7:3635465211015687. Epub 2021 Jun 7.

Department of Orthopaedic Surgery, Division of Sports Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Background: Although minimal clinically important difference (MCID), Patient Acceptable Symptom State (PASS), and substantial clinical benefit (SCB) have been defined for hip-specific legacy patient-reported outcome measures, these metrics have not been defined for the Patient-Reported Outcomes Measurement Information System (PROMIS) instruments for patients undergoing hip arthroscopy.

Purpose: To define the MCID, PASS, and SCB thresholds for the PROMIS Physical Function (PF) computerized adaptive test (CAT) and PROMIS Pain Interference (PI) instruments in patients undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS).

Study Design: Cohort study (Diagnosis); Level of evidence, 2. Read More

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Opioid Prescribing Habits for Common Arthroscopic Procedures in Opioid Naïve Patients.

Orthop J Sports Med 2021 May 21;9(5):23259671211009263. Epub 2021 May 21.

Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Background: With the opioid epidemic and the increasing number of opioid-related deaths, there is growing awareness in the medical community regarding the dangers of opioid overprescription. As a result, there is a willingness among physicians to abandon old norms and adopt new data-driven prescribing practices.

Purpose: To demonstrate patient-reported consumption data of opioid medications after anterior cruciate ligament (ACL) reconstructions (ACLRs), knee arthroscopies, and rotator cuff repairs to provide data-driven guidelines for prescribing opioids after these procedures. Read More

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