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Predicting risk of erectile dysfunction in patients with nonalcoholic fatty liver disease.

Andrologia 2021 May 5:e14091. Epub 2021 May 5.

Department of Urology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.

Nonalcoholic fatty liver disease (NAFLD) is one of the risk factors for erectile dysfunction (ED). We aimed to predict the risk of ED in patients with NAFLD. The study included 146 male patients complaining impotence admitted to the urology outpatient clinic aged 24-80 years without a history of alcohol use who underwent abdominal ultrasonography between February 2018 and January 2019. Read More

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Ultrasonography Grading of Internal Carotid Artery Disease: Multiparametric German Society of Ultrasound in Medicine (DEGUM) versus Society of Radiologists in Ultrasound (SRU) Consensus Criteria.

Ultraschall Med 2021 May 5. Epub 2021 May 5.

Department of Neurology, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.

Purpose:  We sought to determine the diagnostic agreement between the revised ultrasonography approach by the German Society of Ultrasound in Medicine (DEGUM) and the established Society of Radiologists in Ultrasound (SRU) consensus criteria for the grading of carotid artery disease.

Materials And Methods:  Post-hoc analysis of a prospective multicenter study, in which patients underwent ultrasonography and digital subtraction angiography (DSA) of carotid arteries for validation of the DEGUM approach. According to DEGUM and SRU ultrasonography criteria, carotid arteries were independently categorized into clinically relevant NASCET strata (normal, mild [1-49 %], moderate [50-69 %], severe [70-99 %], occlusion). Read More

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Hand-Sewn Versus Stapled Ileal Pouch Anal Anastomoses in Re-Do Setting: Indications, Patient Characteristics, Operative, Functional and Quality of Life Outcomes.

Dis Colon Rectum 2021 Apr 26. Epub 2021 Apr 26.

Inflammatory Bowel Disease Center, NYU Langone Health, NYU Grossman School of Medicine, NY, NY, USA Department of Surgery, Acibadem Mehmet Ali Aydinlar School of Medicine, Istanbul, Turkey.

Background: Impact of the type of anastomosis on the outcomes of re-do ileal pouch anal anastomosis (IPAA) is unknown.

Objective: The aim of this study is to assess the indications, peri-operative and functional outcomes in patients undergoing stapled vs hand-sewn re-do IPAA.

Design: This is a retrospective cohort study. Read More

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Preoperative Nutritional Scores as Host-Related Prognostic Factors for Both Overall Survival and Postoperative Complications in Stage II - III Colorectal Cancer Patients.

Dis Colon Rectum 2021 Apr 26. Epub 2021 Apr 26.

Department of Colorectal Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 1040045, Japan.

Background: In the tumor-node-metastasis eighth edition, nutritional status and inflammatory scores are newly described as host-related prognostic factors for esophageal cancer, hepatocellular carcinoma, and pancreatic cancer. However, only age and race are listed as host-related prognostic factors for colorectal cancer.

Objective: To evaluate the prognostic significance of nutritional and inflammatory scores for postoperative outcomes in colorectal cancer patients. Read More

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Predictors of Positive Circumferential Resection Margin in Rectal Cancer: A Current Audit of the National Cancer Database.

Dis Colon Rectum 2021 Apr 26. Epub 2021 Apr 26.

Postdoctoral Research Fellow, Division of Colorectal Surgery, Department of Surgery, Columbia University Medical Center, New York, NY Postdoctoral Research Fellow, Division of Colorectal Surgery, Department of Surgery, Columbia University Medical Center, New York, NY Postdoctoral Research Fellow, Division of Colorectal Surgery, Department of Surgery, Columbia University Medical Center, New York, NY Chief, Division of Colorectal Surgery, Department of Surgery; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY Assistant Professor, Division of Colorectal Surgery, Department of Surgery; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY.

Background: Positive circumferential resection margin is a predictor of local recurrence and worse survival in rectal cancer. National programs aimed to improve rectal cancer outcomes were first created in 2011, and continue to evolve. The impact on circumferential resection margin during this timeframe has not been fully evaluated in the United States. Read More

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Short-term Outcomes of Day-Case Stoma Closure: A Prospective, Observational Study.

Dis Colon Rectum 2021 Apr 26. Epub 2021 Apr 26.

Department of Digestive Surgery, Amiens University Hospital, Amiens, France SSPC (Simplification of Surgical Patients Care) Clinical Research Unit, University of Picardie Jules Verne, Amiens, France Department of Anaesthesia, Amiens University Hospital, Amiens, France.

Background: Elective stoma closure is a common, standardized procedure in digestive surgery.

Objective: To evaluate the feasibility of day-case surgery for elective stoma closure.

Design: A prospective, single-center, non-randomized study of consecutive patients undergoing day-case elective stoma closure. Read More

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Efficacy of Selective Vidian Neurectomy for Allergic Rhinitis Combined with Chronic Rhinosinusitis.

ORL J Otorhinolaryngol Relat Spec 2021 May 5:1-8. Epub 2021 May 5.

Department of Otorhinolaryngology Head and Neck Surgery, XuanWu Hospital, Capital Medical University, Beijing, China.

Objective: The aim of this study was to investigate the efficacy of endoscopic selective vidian neurectomy in the treatment of severe persistent allergic rhinitis (AR) combined with chronic rhinosinusitis (CRS) with nasal polyps (ARwCRSwNP).

Methods: One hundred thirty patients with moderate to severe persistent ARwCRSwNP were enrolled at Xuanwu Hospital, Capital Medical University, from September 2015 to September 2017. Patients were divided into 2 groups. Read More

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Dynamic Study of Oesophageal Function during Phonation: Simple but Effective.

ORL J Otorhinolaryngol Relat Spec 2021 May 5:1-6. Epub 2021 May 5.

ENT Section, Department of Medical, Surgical and Advanced Technologies G.F. Ingrassia, University of Catania, Catania, Italy.

Secondary aphonia significantly affects the quality of life of the laryngectomy patient despite the excellent success of the operation. Vocal rehabilitation often does not achieve the desired results, given the innumerable prognostic variables. Tracheo-oesophageal speech is considered the standard gold method of voice restoration, but a possible spasm of pharyngo-oesophageal segment is the prominent cause of rehabilitation failure. Read More

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Preoperative Parameters to Predict the Development of Symptomatic Lymphoceles after Radical Prostatectomy.

Urol Int 2021 May 5:1-8. Epub 2021 May 5.

Department of Urology, Uro-Oncology, Robot-assisted and Specialized Urologic Surgery, Cologne University Hospital, Cologne, Germany.

Introduction: Symptomatic lymphoceles (SLs) represent the most common complication after radical prostatectomy (RP) and pelvic lymph node dissection (PLND). To date, preoperative risk factors are missing.

Methods: Clinical and pathological data of 592 patients who underwent RP and PLND were evaluated. Read More

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Bulbar Urethral Stents for Bulbar Urethral Strictures: Long-Term Follow-Up after Stent Removal.

Urol Int 2021 May 5:1-6. Epub 2021 May 5.

Department of Urology, Kocaeli University School of Medicine, Kocaeli, Turkey.

Background/aim: The aim of this study was to assess long-term clinical efficacy of temporary bulbar urethral stent (BUS) used for treatment of recurrent bulbar urethral stricture (US).

Materials And Methods: A total of 168 patients with recurrent bulbar US who underwent BUS placement after internal urethrotomy between 2009 and 2019 were enrolled. An indwelling time of 12 months was planned for the stents. Read More

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Impact of Autologous Transobturator Sling Surgery on Female Sexual Function: A Comparative Study with Mesh Used Mid-Urethral Sling Surgeries.

Urol Int 2021 May 5:1-7. Epub 2021 May 5.

Department of Urology, Kartal Dr. Lutfi Kırdar Traning and Research Hospital, Istanbul, Turkey.

Introduction: To avoid mesh-related complications, autologous transobturator-tape (a-TOT) technique is a viable option in stress urinary incontinence (SUI) surgery. The method differs from TOT and retropubic tape (RT) in the usage of autologous tissue. We hypothesized that a-TOT improves female sexual dysfunction (FSD) more than TOT and RT. Read More

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Efficiency and Clinical Outcomes of Moses Technology with Flexible Ureteroscopic Laser Lithotripsy for Treatment of Renal Calculus.

Urol Int 2021 May 5:1-7. Epub 2021 May 5.

Department of Urology, Beijing Electric Power Hospital, SGCC (State Gird Corporation of China), Beijing, China.

Objective: The aim of the study was to compare the efficiency and clinical outcomes of Moses contact mode (MCM) and regular dusting mode (RDM) during flexible ureteroscopic lithotripsy (FURL) for treatment of renal calculus.

Methods: This retrospective analysis examined 216 patients with renal calculus who underwent FURL with MCM or RDM between March 2015 and January 2020. Stone characteristics, including size, volume, and density, were collected. Read More

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Development of a Multivariable Prediction Model for Citrate Accumulation in Liver Transplant Patients Undergoing Continuous Renal Replacement Therapy with Regional Citrate Anticoagulation.

Blood Purif 2021 May 5:1-11. Epub 2021 May 5.

Surgical Intensive Care Unit, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Introduction: Patients with impaired citrate metabolism may experience citrate accumulation (CA), which causes life-threatening metabolic acidosis and hypocalcemia. CA poses a challenge for clinicians when deciding on the use of regional citrate anticoagulation (RCA) for patients with liver dysfunction. This study aimed to develop a prediction model integrating multiple clinical variables to assess the risk of CA in liver transplant patients. Read More

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Collateral ligament sprains of the metacarpophalangeal joint of the long fingers: Results of a surgical series of 15 patients.

Orthop Traumatol Surg Res 2021 May 2. Epub 2021 May 2.

Institut Montpelliérain de la Main et du Membre Supérieur, Clinique Saint-Roch, 560 Avenue du Colonel Pavelet, 34070 Montpellier, France.

Introduction Collateral ligament sprains of the metacarpophalangeal joint (MP) of the long fingers are rare and mostly treated conservatively. Clinical examination to diagnose the severity of these injuries is mandatory. The purpose of our study is to report the results of 15 patients treated surgically. Read More

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Carotid-Carotid Transposition for Zone 1 Thoracic Endovascular Aortic Repair.

Ann Vasc Surg 2021 May 2. Epub 2021 May 2.

Division of Vascular and Endovascular Surgery, Department of Surgery, University of Kentucky College of Medicine, Lexington, KY, United States.

Objectives: Carotid-carotid bypass (CCB) is the standard technique for cervical aortic arch debranching to maintain left common carotid artery (LCCA) perfusion with zone I thoracic endovascular aortic repair (TEVAR), while left-to-right carotid-carotid transposition (CCT) has been described as an autologous alternative. We report on our center's experience with CCT in the setting of zone I TEVAR. This is the only published series of this technique. Read More

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Associations of clinical frailty with severity of limb threat and outcomes in chronic limb-threatening ischaemia.

Ann Vasc Surg 2021 May 2. Epub 2021 May 2.

Department of Cardiovascular Sciences, University of Leicester, UK; Leicester Vascular Institute, University Hospitals of Leicester NHS Trust, UK; National Institute for Health Research Leicester Biomedical Research Centre - The Glenfield Hospital, Leicester, UK.

Objective: Investigate the relationship of frailty and severity of chronic limb-threatening ischaemia (CLTI), and their comparative associations with one-year outcomes, in patients presenting to a vascular limb salvage (VaLS) clinic.

Methods: This retrospective cohort study utilised data collected from a prospectively maintained VaLS clinic database. Patients aged ≥50 presenting to the VaLS clinic with CLTI between February 2018 and April 2019 were included. Read More

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Predictors of Adherence to Anti-Impulse Therapy Among Patients Treated for Acute Type-B Aortic Dissections.

Ann Vasc Surg 2021 May 2. Epub 2021 May 2.

Division of Vascular Surgery.

Objectives: Medical management remains the mainstay of treatment for patients who present with acute Type-B aortic dissections (TBAD). However, it is unclear whether patients maintain adherence to their anti-impulse therapy medication regimen following hospital discharge. This study was designed to evaluate rates and predictors of medication adherence among insured patients treated for acute TBAD. Read More

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Anxiety and depression scores in patients subjected to arterial revascularization for critical limb ischemia.

Ann Vasc Surg 2021 May 2. Epub 2021 May 2.

Hospital Israelita Albert Einstein, Avenida Albert Einstein, 627, bloco A1, sala 422, Morumbi. ZIP: 05652-900. São Paulo, SP Brazil.

Objectives: This study aims to examine the changes in anxiety and depression scores in 138 patients with critical limb ischemia (rest pain or gangrene) who had no previous psychiatric history, at 30 days and 6 months after surgical revascularization.

Methods: Patients were submitted to a questionnaire-based evaluation using the Beck Anxiety and Depression Inventories before surgery (no more than three days before surgery) ("Pre-Op"), 30 days after surgical revascularization ("Early PO") and at least 6 months after surgical revascularization ("Late PO"). The cut-off scores for depression were (1) < 10, no depression or minimal depression; (2) 10‒18, mild to moderate depression; (3) 19‒29, moderate to severe depression; and (4) 30‒63, severe depression. Read More

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Can 3D pseudo-continuous arterial spin labeling perfusion imaging be applied to predict early response to chemoradiotherapy in patients with advanced nasopharyngeal carcinoma?

Radiother Oncol 2021 May 2. Epub 2021 May 2.

GE Healthcare, MR Research China, Beijing, 100176, China.

Background And Purpose: Chemoradiotherapy (CRT) has been widely applied in patients with advanced nasopharyngeal carcinoma (ANPC). However, limited imaging modality exists on the evaluation of early response to CRT. The purpose of this study was therefore to investigate whether 3D pseudo-continuous arterial spin labeling (3D pCASL) perfusion imaging could predict early response to CRT in ANPC patients. Read More

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A Pilot Study of Guided Conservative Hysteroscopic Evacuation of Early Miscarriage.

J Minim Invasive Gynecol 2021 May 2. Epub 2021 May 2.

Department of Obstetrics and Gynecology, Assuta Ashdod University Hospital, Ashdod, Israel; Faculty of health sciences Ben Gurion University, Israel.

Study Objective: To evaluate initial feasibility and experience with guided hysteroscopic morcellation for uterine evacuation of early miscarriage.

Design: A prospective pilot study of 10 cases.

Setting: A tertiary University hospital in Israel. Read More

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Morbid obesity but not obesity is associated with increased mortality in patients undergoing endoscopic retrograde cholangiopancreatography: A national cohort study.

United European Gastroenterol J 2021 May 5. Epub 2021 May 5.

Department of Emergency Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background: The relationship between body weight and outcomes of endoscopic retrograde cholangiopancreatography (ERCP) is unclear.

Objectives: This study aimed to investigate the impact of obesity and morbid obesity on mortality and ERCP-related complications in patients who underwent ERCP.

Methods: We conducted a US population-based retrospective cohort study using the Nationwide Readmissions Databases (2013-2014). Read More

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Use of a Double Reverse Traction Repositor versus a Traction Table for the Treatment of Intertrochanteric Femur Fractures: A Comparative Study.

Orthop Surg 2021 May 5. Epub 2021 May 5.

Department of Orthopaedic Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.

Objective: The aim of the present study was to compare the clinical results for unstable femoral intertrochanteric fractures treated with a double reverse traction repositor (DRTR) and those treated using a traction table with the Asia proximal femoral nail antirotation (PFNA-II).

Methods: A retrospective study was performed including 95 patients with AO/OTA type 31-A2 and 31-A3 unstable femoral intertrochanteric fractures who underwent DRTR or traction table-facilitated PFNA-II nailing from April 2015 to December 2018 in our traumatic center. Demographics, duration of operation, blood loss, part loading time after surgery, fracture healing time, and early and late complications were assessed. Read More

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Interictal spike networks predict surgical outcome in patients with drug-resistant focal epilepsy.

Ann Clin Transl Neurol 2021 May 5. Epub 2021 May 5.

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Quebec, Canada.

Objective: To determine if properties of epileptic networks could be delineated using interictal spike propagation seen on stereo-electroencephalography (SEEG) and if these properties could predict surgical outcome in patients with drug-resistant epilepsy.

Methods: We studied the SEEG of 45 consecutive drug-resistant epilepsy patients who underwent subsequent epilepsy surgery: 18 patients with good post-surgical outcome (Engel I) and 27 with poor outcome (Engel II-IV). Epileptic networks were derived from interictal spike propagation; these networks described the generation and propagation of interictal epileptic activity. Read More

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Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle.

J Cachexia Sarcopenia Muscle 2021 May 5. Epub 2021 May 5.

Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.

Background: In vivo muscle protein synthesis rates are typically assessed by measuring the incorporation rate of stable isotope labelled amino acids in skeletal muscle tissue collected from vastus lateralis muscle. It remains to be established whether muscle protein synthesis rates in the vastus lateralis are representative of muscle protein synthesis rates of other muscle groups. We hypothesized that post-absorptive muscle protein synthesis rates differ between vastus lateralis and rectus abdominis, pectoralis major, or temporalis muscle in vivo in humans. Read More

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Large pulmonary sclerosing pneumocytoma in a young female: A rare lung tumor.

Thorac Cancer 2021 May 5. Epub 2021 May 5.

Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.

We report a case of a 28-year-old female who presented with a solid mass lesion in the right middle lobe (RML). A chest computed tomography (CT) scan showed a 3.5 cm sized round and solid mass between the medial and lateral segment of the RML. Read More

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Cortical [ F]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes.

Mov Disord 2021 May 5. Epub 2021 May 5.

German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Background: Corticobasal syndrome is associated with cerebral protein aggregates composed of 4-repeat (~50% of cases) or mixed 3-repeat/4-repeat tau isoforms (~25% of cases) or nontauopathies (~25% of cases).

Objectives: The aim of this single-center study was to investigate the diagnostic value of the tau PET-ligand [ F]PI-2620 in patients with corticobasal syndrome.

Methods: Forty-five patients (71. Read More

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Hydration and glycogen affect T relaxation times of liver tissue.

NMR Biomed 2021 May 5:e4530. Epub 2021 May 5.

The Oxford Centre for Clinical Magnetic Resonance Research (OCMR), University of Oxford, Oxford, UK.

T mapping is a useful tool for the assessment of patients with nonalcoholic fatty liver disease but still suffers from a large unexplained variance in healthy subjects. This study aims to characterize the potential effects of liver glycogen concentration and body hydration status on liver shortened modified Look-Locker inversion recovery (shMOLLI) T measurements. Eleven glycogen phantoms and 12 healthy volunteers (mean age: 31 years, three females) were scanned at 3 T using inversion recovery spin echo, multiple contrast spin echo (in phantoms), shMOLLI T mapping, multiple-echo spoiled gradient recalled echo and C spectroscopy (in healthy volunteers). Read More

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What is the Optimal Method Assessing for Persistent Villous Atrophy in Adult Coeliac Disease?

J Gastrointestin Liver Dis 2021 May 3. Epub 2021 May 3.

Academic Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, United Kingdom.

Background And Aims: Methods of assessing gluten-free diet (GFD) adherence in adults with coeliac disease (CD) include serological testing, dietitian evaluation, questionnaires and repeat duodenal biopsies. Persisting villous atrophy (VA) is associated with CD complications, however gastroscopy with biopsies is expensive and invasive. This study aimed to assess the abilities of a duodenal bulb (D1) biopsy and the Celiac Dietary Adherence Test (CDAT) to detect persisting VA in adults with CD. Read More

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Increased mortality with REBOA only mitigated by strong unmeasured confounding: an expanded analysis using the National Trauma Data Bank.

J Trauma Acute Care Surg 2021 May 5. Epub 2021 May 5.

Department of Surgery, Yale School of Medicine Applied Mathematics Program, Department of Mathematics, Yale University Department of Statistics and Data Science, Yale University.

REBOA is being increasingly adopted to manage non-compressible torso hemorrhage, but a recent analysis of the 2015-2016 Trauma Quality Improvement Project (TQIP) dataset showed that placement of REBOA was associated with higher rates of death, lower extremity amputation, and acute kidney injury (AKI). We expand this analysis by including the 2017 dataset, quantifying the potential role of residual confounding, and distinguishing between traumatic and ischemic lower extremity amputation.

Methods: This retrospective study used the 2015-2017 TQIP database and included patients older than 18 years old, with signs of life on arrival, no aortic injury, and were not transferred. Read More

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Breast surgery for young women with early-stage breast cancer: Mastectomy or breast-conserving therapy?

Medicine (Baltimore) 2021 May;100(18):e25880

Department of General Surgery.

Abstract: Whether breast-conserving therapy (BCT) should be chosen as a local treatment for young women with early-stage breast cancer is controversial. This study compared the survival benefits of BCT or mastectomy in young women under 40 with early-stage breast cancer and further explored age-stratified outcomes. This study investigated whether there is a survival benefit when young women undergo BCT compared with mastectomy. Read More

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