Neuroimage 2017 02 19;146:492-506. Epub 2016 Sep 19.
Institute of Gerontology, Wayne State University, Detroit, MI, USA; Department of Psychology, Wayne State University, Detroit, MI, USA.
Age-related declines in spatial navigation are associated with deficits in procedural and episodic memory and deterioration of their neural substrates. For the lack of longitudinal evidence, the pace and magnitude of these declines and their neural mediators remain unclear. Here we examined virtual navigation in healthy adults (N=213, age 18-77 years) tested twice, two years apart, with complementary indices of navigation performance (path length and complexity) measured over six learning trials at each occasion. Read More