157 results match your criteria passive disinfection

Preclinical evaluation of passive disinfection caps with a long-term catheter for the prevention of catheter-related bloodstream infection in pediatric cancer patients.

GMS Hyg Infect Control 2021 31;16:Doc20. Epub 2021 May 31.

Medical Solutions Division Laboratory, Europe, Middle East and Africa, 3M Deutschland GmbH, Neuss, Germany.

The use of passive disinfection devices (disinfection caps) may be a beneficial part of a maintenance care bundle, aiming at the prevention of catheter-related bloodstream infections in pediatric cancer patients. This preclinical investigation tested the visual and mechanical integrity of a Broviac™ catheter hub after simulation testing with 122 3M™ CurosTM Stopper Disinfection Caps for Open Female Luers repeatedly attached and removed over 6 months. We found that these catheter hubs were compatible, fully operational, and airtight with use of 3M Curos stopper caps after 6 months of use with 122 caps per catheter hub. Read More

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Proteomic analysis reveals the mechanism of different environmental stress-induced tolerance of Pseudomonas aeruginosa to monochloramine disinfection.

J Hazard Mater 2021 May 14;417:126082. Epub 2021 May 14.

Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou 730000, PR China. Electronic address:

Although drinking water disinfection proved to be an effective strategy to eliminate many pathogens, bacteria can still show disinfection tolerance in drinking water distribution systems. To date, the molecular mechanisms on how environmental stress affects the tolerance of Pseudomonas aeruginosa to monochloramine are not well understood. Here, we investigated how three stress conditions, namely starvation, low temperature, and starvation combined with low temperature, affected the monochloramine tolerance of Pseudomonas aeruginosa, an opportunistic pathogen commonly found in drinking water distribution systems. Read More

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Bioburden contamination and Staphylococcus aureus colonization associated with firefighter's ambulances.

Environ Res 2021 Jun 22;197:111125. Epub 2021 Apr 22.

H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, Portugal; NOVA National School of Public Health, Public Health Research Centre, Universidade NOVA de Lisboa, Portugal; Comprehensive Health Research Center (CHRC), Portugal.

Ambulance vehicles are an essential part of emergency clinical services. Bioburden control in ambulances, through cleaning and disinfection, is crucial to minimize hospital-acquired infections, cross contamination and exposure of patients and ambulances' crew. In Portugal, firefighter crews are responsible, besides fire extinction, for first aid and urgent pre-hospital treatment. Read More

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An experimental intraradicular biofilm model in the pig for evaluating irrigation techniques.

BMC Oral Health 2021 04 7;21(1):177. Epub 2021 Apr 7.

Division of Operative Dentistry, Department of Ecological Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aobaku, Sendai, Miyagi, 980-8575, Japan.

Background: We established an in vivo intraradicular biofilm model of apical periodontitis in pigs in which we compared the efficacy of different irrigant activation techniques for biofilm removal.

Methods: Twenty roots from the deciduous mandibular second premolar of 5 male pigs were used. After pulpectomy, canals were left open for 2 weeks and then sealed for 4 weeks to enable the development of an intracanal biofilm. Read More

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Bacterial Reduction in Oval-Shaped Root Canals After Different Irrigant Agitation Methods.

Eur Endod J 2021 Apr 8;6(1):110-116. Epub 2021 Mar 8.

Department of Proclin, Faculty of Dentistry, Rio de Janeiro State University, Rio de Janeiro, Brazil.

Objective: This study aimed to assess the antibacterial effect of Easy Clean®, passive ultrasonic irrigation and sonic irrigation against Enterococcus faecalis biofilm in oval-shaped canals.

Methods: Fifty-five extracted human teeth with similar dimensions were selected. Access cavities were prepared and the root canals were instrumented using Wave One® Primary files (25. Read More

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Central venous catheter insertion: Review of recent evidence.

Best Pract Res Clin Anaesthesiol 2021 May 10;35(1):135-140. Epub 2020 Dec 10.

Anesthesiology Department, Hospital General Universitario Gregorio Marañón Madrid, Spain; Ciber de Enfermedades Respiratorias (CIBERES) CIBER (CB06/06/0058) Madrid, Spain; Clinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón Madrid, Spain.

Guidelines for prevention of catheter-related bloodstream infection (CR-BSI) describe a series of recommendations for correct insertion and handling of central venous catheters (CVCs). Since their implementation, quality programs such as "Zero bacteremia" have achieved a reduction in CR-BSI rates, but there is still room for further improvement. New evidence is emerging regarding, e. Read More

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Treatment and control strategies for COVID-19: Prospects and possibilities.

Pak J Pharm Sci 2020 Jul;33(4):1727-1730

Department of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan.

COVID-19 is a highly contagious and infectious disease, spreading rapidly worldwide. Its high spread rate has turned it into public stigma. The current study is focusing on its treatment and control strategies on the basis of the facts and figs obtained from previous studies. Read More

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First reported outbreak of the emerging pathogen Candida auris in Canada.

Am J Infect Control 2021 06 21;49(6):804-807. Epub 2021 Jan 21.

Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Division of Medical Microbiology & Infection Control, Vancouver Coastal Health Authority, Vancouver, British Columbia, Canada. Electronic address:

Background: Candida auris was first described in Japan in 2009 and has since been detected in over 40 countries. The yeast is concerning for multiple reasons, primarily: (1) challenges with accurate identification; (2) reported multidrug resistance; (3) published mortality rates of 30%-60%; and (4) persistence in the environment associated with human transmission. We report the emergence of a healthcare-associated cluster in the Greater Vancouver area in 2018 and describe the measures implemented to contain its transmission. Read More

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Various wastewaters treatment by sono-electrocoagulation process: A comprehensive review of operational parameters and future outlook.

Chemosphere 2021 Jan 12;263:128314. Epub 2020 Sep 12.

Department of Food Science, Faculty of Food Engineering, State University of Campinas (UNICAMP), 13083-862, Campinas, São Paulo, Brazil. Electronic address:

Electrochemical processes are a promising alternative to traditional water treatment systems because they have advantages than conventional techniques such as chemical storage, small treatment systems, no alkalinity depletion, remote adjustment, and cost-effectiveness. The most crucial electrochemical method is Electrocoagulation (EC). Through creating cationic species, the EC causes the neutralization of pollutant surface charges and destabilizes suspended, emulsified or dissolved contaminants led to attracting particles of opposite charge and form flocculants. Read More

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January 2021

Coronavirus Disease 2019 (COVID-19): The Singapore Experience. A Review of the First Eight Months.

Ann Acad Med Singap 2020 Oct;49(10):764-778

Department of Medicine, National University Hospital.

As of 27 October 2020, there have been 57,980 confirmed cases of COVID-19 in Singapore, with 28 fatalities. To summarise the Singapore experience in managing and containing COVID-19 based on available published data and from relevant sources, a review of literature using research databases such as PubMed and OVID Medline, along with non-peer-reviewed articles and other sources, was conducted with the search terms 'COVID-19' and 'Singapore'. Research conducted in Singapore has provided insight into the clinical manifestations and period of infectivity of COVID-19, demonstrated evidence of pre-symptomatic transmission, linked infection clusters using serological tools, and highlighted aspects of hospital-based environmental contamination. Read More

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October 2020

ability of a noninstrumentation technique to disinfect oval-shaped canals.

J Conserv Dent 2020 Jan-Feb;23(1):10-14. Epub 2020 Oct 10.

Department of Orthodontics, Lebanese University, Beirut, Lebanon.

Context: Oval-shaped canals represent a challenge in endodontics. Infected tissue may remain in their recesses. This concern may be more critical with minimally instrumentation techniques. Read More

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October 2020

Solar heating to inactivate thermal-sensitive pathogenic microorganisms in vehicles: application to COVID-19.

Environ Chem Lett 2020 Nov 6:1-8. Epub 2020 Nov 6.

Department of Environmental Science and Engineering, Xi'an Jiaotong University, Xi'an, 710049 People's Republic of China.

Disinfection is a common practice to inhibit pathogens, yet success is limited by microbial adaptation and our poor knowledge of viral transmission, notably in the current COVID-19 pandemic. There is a need for alternative disinfection strategies and techniques that are adapted to the actual behavior of humans living in densely populated mega-cities. Here, high public circulation in shared passenger vehicles such as taxis, buses and personal cars represents a major risk of viral transmission due to confined space and commonly touched surfaces. Read More

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November 2020

Development of a personal passive air sampler for estimating exposure to effective chlorine while using chlorine-based disinfectants.

Indoor Air 2021 Mar 7;31(2):557-565. Epub 2020 Oct 7.

Division of Environmental Science and Ecological Engineering, Korea University, Seoul, Republic of Korea.

With an increasing use of indoor disinfectants such as chlorine (Cl ) and hypochlorous acid, a convenient sampler for estimating exposure to oxidants, such as effective chlorine, is necessary. Here, we developed a personal passive air sampler (PPAS) composed of a redox dye, o-dianisidine, in a polydimethylsiloxane (PDMS) sheet. o-Dianisidine readily reacts with gaseous oxidants generated by bleach usage, and its color changes as the reaction progresses; hence, personal exposure to effective chlorine could be easily detected by the naked eye, while cumulative exposure could be determined by measuring concentrations of o-dianisidine reacting with it. Read More

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Effective treatment of greywater via green wall biofiltration and electrochemical disinfection.

Water Res 2020 Oct 24;185:116228. Epub 2020 Jul 24.

Environmental and Public Health Microbiology Laboratory (EPHM Lab), Department of Civil Engineering, Faculty of Engineering, Monash University, Clayton, VIC 3800, Australia.

Low energy and cost solutions are needed to combat raising water needs in urbanised areas and produce high quality recycled water. In this study, we investigated key processes that drive a unique greywater treatment train consisting of a passive green wall biofiltration system followed by disinfection using a Boron-doped diamond (BDD) electrode with a solid polymer electrolyte (SPE). In both systems, the treatment was performed without any additional chemicals and pollutants of concern were monitored for process evaluation. Read More

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October 2020

Guidelines for COVID-19 Management in Hematopoietic Cell Transplantation and Cellular Therapy Recipients.

Biol Blood Marrow Transplant 2020 11 28;26(11):1983-1994. Epub 2020 Jul 28.

Levine Cancer Institute/Atrium Health, Charlotte, North Carolina.

There are currently limited data on the epidemiology, clinical manifestations, and optimal management of Coronavirus Disease 2019 (COVID-19) in hematopoietic cell transplantation and cellular therapy recipients. Given the experience with other respiratory viruses, we anticipate that patients may develop severe clinical disease and thus provide the following general principles for cancer centers across the nation. These guidelines were developed by members of the American Society for Transplantation and Cellular Therapy Infectious Diseases Special Interest Group. Read More

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November 2020

Susceptibility of the complex to drying: Implications for nebulizer hygiene in patients with cystic fibrosis.

Int J Mycobacteriol 2020 Apr-Jun;9(2):173-175

Department of Bacteriology, Northern Ireland Public Health Laboratory, Belfast City Hospital, Belfast; School of Biomedical Sciences, Ulster University, Coleraine; School of Medicine, Dentistry and Biomedical Science, The Wellcome.Wolfson Institute for Experimental Medicine, Queenfs University, Belfast, Northern Ireland.

Background: Nebulizer hygiene and care is important in cystic fibrosis (CF) to minimize device contamination from bacteria, including nontuberculous mycobacteria (NTMs). Most nebulizer manufacturers recommend nebulizer drying, however there is little evidence to understand how nebulizer drying affects NTM survival.

Methods: Mycobacterium abscessus subsp. Read More

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Efficacy of Erbium, Chromium-doped Yttrium, Scandium, Gallium and Garnet Laser-activated Irrigation Compared with Passive Ultrasonic Irrigation, Conventional Irrigation, and Photodynamic Therapy against .

J Contemp Dent Pract 2020 Jan 1;21(1):11-16. Epub 2020 Jan 1.

Department of Endodontics, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey.

Aim: To compare the antimicrobial effects of two different irrigation solutions activated with erbium, chromium-doped yttrium, scandium, gallium and garnet (Er,Cr:YSGG) laser or an ultrasonic system and a photodynamic therapy (PDT) on ().

Materials And Methods: The root canals of 72 single-rooted human permanent incisors were prepared with ProTaper Universal rotary instruments and incubated with (ATCC 29212) for 4 weeks. Then the teeth were randomly divided into seven experimental groups with 10 specimens for canal disinfection procedures. Read More

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January 2020

Effects of Contemporary Irrigant Activation Schemes and Subsequent Placement of an Interim Dressing on Bacterial Presence and Activity in Root Canals Associated with Asymptomatic Apical Periodontitis.

J Clin Med 2020 Mar 20;9(3). Epub 2020 Mar 20.

Department of Dentistry, School of Dentistry, University of São Paulo, São Paulo 05508-000, Brazil.

New tools for activating endodontic irrigants have evolved, yet their impact on root canal disinfection, in comparison to the passive placing of an inter-visit medication, have not yet been fully elucidated. The use of DNA- and rRNA-based methods may cast some new light on this issue, as they allow a comparison to be made between microbial presence and activity. Therefore, the aim of this single-arm intervention trial is to evaluate the antibacterial effect of endodontic procedures using both molecular methods. Read More

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Vibrational and sonochemical characterization of ultrasonic endodontic activating devices for translation to clinical efficacy.

Mater Sci Eng C Mater Biol Appl 2020 Apr 7;109:110646. Epub 2020 Jan 7.

Marquette University School of Dentistry, Milwaukee, WI 53233, USA. Electronic address:

Passive activation of endodontic irrigants provides improved canal disinfection, smear layer removal, and better subsequent sealing. Although evidence suggests that passive activating endodontic devices increase the effectiveness of irrigation, no study exists to quantitatively compare and validate vibrational characteristics and cavitation produced by different ultrasonic endodontic devices. The current study aims to compare the efficiency of various commercially available ultrasonic endodontic activating devices (i. Read More

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Effects of Individual and Combined Water, Sanitation, Handwashing, and Nutritional Interventions on Child Respiratory Infections in Rural Kenya: A Cluster-Randomized Controlled Trial.

Am J Trop Med Hyg 2020 06;102(6):1286-1295

Civil and Environmental Engineering, Tufts University, Medford, Massachusetts.

Poor nutrition and hand hygiene are risk factors for acute respiratory infections (ARIs). Safe drinking water and sanitation can reduce exposure to pathogens and encourage healthy immune responses, reducing the risk of ARIs. Within a trial assessing impacts of water, sanitation, and handwashing (WASH), and nutritional interventions, we evaluated effects on ARIs. Read More

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Comparative Analysis of Biofilm Removal Efficacy by Multisonic Ultracleaning System and Passive Ultrasonic Activation.

Materials (Basel) 2019 Oct 25;12(21). Epub 2019 Oct 25.

Dental Research Institute and School of Dentistry, Conservative Dentistry, Seoul National University, Seoul 03080, Korea.

The purpose of this study was to compare disinfection and the biofilm removal efficacy of the GentleWave System (Sonendo, Inc., Laguna Hills, CA, USA) with passive ultrasonic activation method. Forty-seven freshly extracted human molars were inoculated with and cultured for five weeks to establish biofilm. Read More

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October 2019

Sources and reservoirs of NRCS-A inside a NICU.

Antimicrob Resist Infect Control 2019 17;8:157. Epub 2019 Oct 17.

1Centre International de Recherche en Infectiologie (CIRI), INSERM U1111, CNRS UMR5308, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.

Background: The methicillin-resistant clone NRCS-A, involved in sepsis in neonatal intensive care units (NICUs) worldwide, is able to persist and spread in NICUs, suggesting the presence of reservoirs inside each setting. The purpose of the present study was to identify these reservoirs and to investigate the cycle of transmission of NRCS-A in one NICU.

Methods: In a single institution study, NRCS-A was sought in 106 consecutive vaginal samples of pregnant women to identify a potential source of NRCS-A importation into the NICU. Read More

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Antibiofilm Activity of Three Different Irrigation Techniques: An in Vitro Study.

Antibiotics (Basel) 2019 Aug 9;8(3). Epub 2019 Aug 9.

Unità Operativa Complessa (UOC) Odontoiatria Generale e Ortodonzia, Dipartimento Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della Testa Collo. Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.

The microbial infection of the endodontic space occurs in a necrotic tooth as a result of dental caries, trauma, periodontal disease, or previous root canal therapy. The disruption of the biofilms and the reduction of the bacterial load inside root canals are crucial for the success of root canal therapy. The aim of this study was to compare, in vitro, the antibiofilm efficacy of a novel passive sonic irrigation (PSI) device with passive ultrasonic irrigation (PUI) and conventional needle irrigation (CNI). Read More

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Passive Ceiling Light Disinfection System to Reduce Bioburden in an Intensive Care Unit.

J Pediatr Intensive Care 2019 Sep 28;8(3):138-143. Epub 2018 Dec 28.

Department of Family, Population and Preventive Medicine, Stony Brook University, Stony Brook, New York, United States.

A ceiling-installed narrow spectrum (402-420 nm) bactericidal blue light disinfection system was installed in a large suburban medical intensive care unit (ICU) and evaluated for implementation feasibility and effectiveness in reducing environmental bioburden. Installation of 54 ceiling devices was accomplished at low cost and with minimal ICU process disruption. Postinstallation high-touch surface colony counts were significantly lower than preinstallation. Read More

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September 2019

Effectiveness of passive ultrasonic irrigation on periapical healing and root canal disinfection: a systematic review.

Br Dent J 2019 Aug;227(3):228-234

Pediatric Dentistry, State University of Rio de Janeiro, Preventive and Community Dentistry, Rio de Janeiro, Brazil.

Objectives To evaluate the effectiveness of passive ultrasonic irrigation (PUI) compared with non-activated irrigation (NAI) on periapical healing and root canal disinfection.Data source A comprehensive search without restrictions was performed in the following systematic electronic databases: PubMed, Scopus, Cochrane, Web of Science, ScienceDirect and OpenGrey. Additional studies were sought through hand-searching in the main endodontic journals. Read More

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Er,Cr:YSGG Laser-Activated Irrigation and Passive Ultrasonic Irrigation: Comparison of Two Strategies for Root Canal Disinfection.

Photobiomodul Photomed Laser Surg 2020 Feb 9;38(2):91-97. Epub 2019 Aug 9.

Laboratory of Molecular Microbiology and Antimicrobials, Department of Pathology and Experimental Therapeutics, Faculty of Medicine, University of Barcelona, Barcelona, Spain.

To compare the antibacterial effectiveness of 0.5% sodium hypochlorite (NaOCl) activated by the Er,Cr:YSGG laser-activated irrigation (LAI) and passive ultrasonic irrigation (PUI) against a 10-day-old intracanal biofilm. LAI and PUI are regarded as alternative methods to release the irrigant in the inner regions of the root canal system achieving enhanced cleaning ability. Read More

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February 2020

A functionalized TiO/MgTiO nano-layer on biodegradable magnesium implant enables superior bone-implant integration and bacterial disinfection.

Biomaterials 2019 10 25;219:119372. Epub 2019 Jul 25.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, China; Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma, The University of Hong Kong Shenzhen Hospital, 1 Haiyuan 1st Road, Futian District, Shenzhen, China. Electronic address:

Rapid corrosion of biodegradable magnesium alloys under in vivo condition is a major concern for clinical applications. Inspired by the stability and biocompatibility of titanium oxide (TiO) passive layer, a functionalized TiO/MgTiO nano-layer has been constructed on the surface of WE43 magnesium implant by using plasma ion immersion implantation (PIII) technique. The customized nano-layer not only enhances corrosion resistance of Mg substrates significantly, but also elevates the osteoblastic differentiation capability in vitro due to the controlled release of magnesium ions. Read More

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October 2019

The case for using a disinfecting cap for needlefree connectors.

Andrew Barton

Br J Nurs 2019 Jul;28(14):S22-S27

Advanced Nurse Practitioner, Vascular Access and IV Therapy Lead, Frimley Health NHS Foundation Trust.

Catheter-related bloodstream infections (CRBSIs) are a signification cause of infection. When CRBSI rates are high, the cost to the patient and the organisation can be significant. More than ever before, there is a high demand for vascular access. Read More

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Distribution of sodium hypochlorite throughout the mesial root canal system of mandibular molars after adjunctive irrigant activation procedures: a micro-computed tomographic study.

Clin Oral Investig 2020 Feb 26;24(2):907-914. Epub 2019 Jun 26.

Department of Endodontics, Faculty of Dentistry, Estácio de Sá University, Av. Alfredo Baltazar da Silveira, 580/cobertura, Recreio, Rio de Janeiro, RJ, 22790-010, Brazil.

Objectives: To evaluate and compare irrigant distribution throughout the root canal system of mesial roots of mandibular molars after application of distinct adjunctive irrigant activation procedures.

Materials And Methods: Fifteen extracted mandibular molars presenting Fan's type II, III, or IV isthmus configurations were selected. The canals were initially enlarged and cleaned. Read More

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February 2020

New prebiotic chemistry inspired filter media for stormwater/greywater disinfection.

J Hazard Mater 2019 10 7;378:120749. Epub 2019 Jun 7.

Environmental and Public Health Microbiology Laboratory (EPHM Lab), Department of Civil Engineering, Monash University, Clayton, Victoria 3800, Australia; Cooperative Research Centre for Water Sensitive Cities, Melbourne, Victoria 3800, Australia. Electronic address:

Greywater and stormwater have received significant attention due to increasing water scarcity. Passive filtration such as biofiltration has been a popular treatment method with its low energy input and environmental friendliness. However, pathogen removal capacity needs improvement to achieve safe water quality. Read More

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October 2019