136 results match your criteria participants flagged


Use of bot and content flags to limit the spread of misinformation among social networks: a behavior and attitude survey.

Soc Netw Anal Min 2021 12;11(1):32. Epub 2021 Mar 12.

University of Alabama in Huntsville, Huntsville, AL USA.

The COVID-19 infodemic is driven partially by Twitter bots. Flagging bot accounts and the misinformation they share could provide one strategy for preventing the spread of false information online. This article reports on an experiment ( = 299) conducted with participants in the USA to see whether flagging tweets as coming from bot accounts and as containing misinformation can lower participants' self-reported engagement and attitudes about the tweets. Read More

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The Surprise Question and Serious Illness Conversations: A pilot study.

Nurs Ethics 2021 Mar 9:969733020983392. Epub 2021 Mar 9.

Providence Health Care, Canada.

Background: Serious Illness Conversations aim to discuss patient goals. However, on acute medicine units, seriously ill patients may undergo distressing interventions until death.

Objectives: To investigate the feasibility of using the Surprise Question, "Would you be surprised if this patient died within the next year?" to identify patients who would benefit from early Serious Illness Conversations and study any changes in the interdisciplinary team's beliefs, confidence, and engagement as a result of asking the Surprise Question. Read More

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Monitoring the effects of COVID-19 in emerging adults with pre-existing mood and anxiety disorders.

Early Interv Psychiatry 2021 Mar 3. Epub 2021 Mar 3.

Lawson Health Research Institute, London Health Sciences Centre, London, Ontario, Canada.

Aim: The COVID-19 quarantine closed many mental health services. Emerging adults with pre-existing mood or anxiety disorders were of concern for worsening symptoms. We sought to demonstrate a method for monitoring mental health status of a group of patients with reduced access to their usual mental health services during quarantine. Read More

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Underrecognized Patterns of High-Grade Squamous Intraepithelial Lesion on ThinPrep Preparations.

Am J Clin Pathol 2021 Feb 25. Epub 2021 Feb 25.

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine-New York Presbyterian Hospital, New York, NY, USA.

Objectives: To identify less readily identifiable patterns of high-grade squamous intraepithelial lesions (HSIL) in negative human papillomavirus (HPV)-positive Papanicolaou (Pap) tests on ThinPrep preparations.

Methods: Of all HPV-positive Pap tests that were negative for intraepithelial lesion or malignancy (NILM) from July 2013 to June 2018, those with HSIL on subsequent histology within 6 months were identified. ThinPrep slides from the latter group (group 1) and from NILM HPV-negative Pap tests with negative follow-up (group 2) were reviewed independently by 4 participants. Read More

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February 2021

Increasing vaccine acceptance using evidence-based approaches and policies: Insights from research on behavioural and social determinants presented at the 7th Annual Vaccine Acceptance Meeting.

Int J Infect Dis 2021 Apr 9;105:188-193. Epub 2021 Feb 9.

Sanofi Pasteur, 14 Espace Henry Vallee, 69007, Lyon, France. Electronic address:

Background: In 2019, the World Health Organization (WHO) flagged vaccine hesitancy as one of the top 10 threats to global health. The drivers of and barriers to under-vaccination include logistics (access to and awareness of affordable vaccines), as well as a complex mix of psychological, social, political, and cultural factors.

Increasing Vaccine Uptake: There is a need for effective strategies to increase vaccine uptake in various settings, based on the best available evidence. Read More

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Evaluating Depressive Symptoms Among Low-Socioeconomic-Status African American Women Aged 40 to 75 Years With Uncontrolled Hypertension: A Secondary Analysis of a Randomized Clinical Trial.

JAMA Psychiatry 2021 Apr;78(4):426-432

Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public, Baltimore, Maryland.

Importance: Depression is one of the leading causes of disability in the United States. African American women of low socioeconomic status with uncontrolled hypertension are at risk of having severe depressive symptoms, yet there is limited research about the mental health of this vulnerable population. Data from the Prime Time Sister Circles randomized clinical trial (PTSC-RCT) study can shed light on the prevalence of depressive symptoms among low-socioeconomic-status older African American women with hypertension. Read More

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Using a Quality Improvement Model to Implement Distress Screening in a Community Cancer Setting.

J Adv Pract Oncol 2020 Nov-Dec;11(8):825-834. Epub 2020 Nov 1.

Cancer Support Community, Valley/Ventura/Santa Barbara, Westlake Village, California.

Background: Quality cancer care includes routine screening for psychosocial distress. This quality improvement project focused on the implementation of distress screening at a licensed affiliate of Cancer Support Community, a community-based non-profit organization that provides professionally led cancer support.

Methods: An advanced practice oncology nurse assisted the staff in implementing and evaluating the process of distress screening. Read More

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November 2020

Frailty and potentially inappropriate medications using the 2019 Beers Criteria: findings from the Australian Longitudinal Study on Women's Health (ALSWH).

Aging Clin Exp Res 2021 Jan 15. Epub 2021 Jan 15.

University of Newcastle, University Drive, Callaghan, NSW, 2308, Australia.

Background: Frailty is an essential consideration with potentially inappropriate medications (PIMs), especially among older women.

Aims: This study determined the use of potentially inappropriate medications according to frailty status using the Beers Criteria 2019, identified medications that should be flagged as potentially inappropriate and harmful depending on individual health factors, and determined the association between frailty and PIMs, adjusted for characteristics associated with PIMs.

Methods: This prospective longitudinal study included 9355 participants aged 77-82 years at baseline (2003). Read More

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January 2021

Validation of PHASE for deriving N-acetyltransferase 2 haplotypes in the Western Cape mixed ancestry population.

Afr J Lab Med 2020 17;9(1):988. Epub 2020 Dec 17.

Division of Chemical Pathology, University of Cape Town, Cape Town, South Africa.

Background: There is a shortage of data on the accuracy of statistical methods for the prediction of N-acetyltransferase 2 () haplotypes in the mixed ancestry population of the Western Cape.

Objective: This study aimed to identify the haplotypes and assess the accuracy of PHASE version 2.1. Read More

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December 2020

Train-the-trainer: Pilot trial for ebola virus disease simulation training.

Educ Health (Abingdon) 2020 May-Aug;33(2):37-45

Department of Anesthesia and Perioperative Medicine; Dean Emeritus and Distinguished University Professor, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

Background: Highly infectious but rare diseases require rapid dissemination of safety critical skills to health-care workers (HCWs). Simulation is an effective method of education; however, it requires competent instructors. We evaluated the efficacy of an internet-delivered train-the-trainer course to prepare HCWs to care for patients with Ebola virus disease (EVD). Read More

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December 2020

Evaluating the performance of the visual half field paradigm as a screening tool to detect right hemispheric language dominance.

Laterality 2020 Nov;25(6):722-739

Department of Experimental Psychology, Ghent University, Gent, Belgium.

Language is among the most studied functional asymmetries, yet little is known about right hemispheric language dominance. Because of its low prevalence, including a big sample of individuals with this variant of brain organization implies testing large groups, which may not be feasible when using expensive techniques. One solution involves screening a large sample using a cost-efficient method and next inviting only those participants flagged as potentially right dominant for follow-up investigation. Read More

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November 2020

Defining culturally safe primary care for people who use substances: a participatory concept mapping study.

BMC Health Serv Res 2020 Nov 23;20(1):1060. Epub 2020 Nov 23.

Technology Enterprise Facility, Canadian Institute for Substance Use Research, University of Victoria, PO Box 1700 STN CSC, Victoria, BC, V8W 2Y2, Canada.

Background: People who use substances experience high levels of substance-related stigma, both within and outside of health care settings, which can prevent people from help-seeking and contribute further to health inequities. Recognizing and respecting how political, social, economic, and historical conditions influence health and health care, cultural safety, with origins in addressing Indigenous racism, is a potential strategy for mitigating stigma and marginalization in health care. Using a participatory research approach, we applied the concept of cultural safety to develop a model of safe primary care from the perspective of people who use substances. Read More

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November 2020

Adaptation of a Digital Health Innovation to Prevent Relapse and Support Recovery in Youth Receiving Services for First-Episode Psychosis: Results From the Horyzons-Canada Phase 1 Study.

JMIR Form Res 2020 Oct 29;4(10):e19887. Epub 2020 Oct 29.

Centre for Youth Mental Health, The University of Melbourne, Parkville, Australia.

Background: Developing a digital health innovation can require a substantial amount of financial and human resource investment before it can be scaled for implementation across geographical, cultural, and health care contexts. As such, there is an increased interest in leveraging eHealth innovations developed and tested in one country or jurisdiction and using these innovations in local settings. However, limited knowledge exists on the processes needed to appropriately adapt digital health innovations to optimize their transferability across geographical, cultural, and contextual settings. Read More

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October 2020

Safety Protocols for Adolescent Substance Use Research in Clinical Settings.

J Adolesc Health 2021 May 28;68(5):999-1005. Epub 2020 Sep 28.

Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Division of Adolescent/Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts; Computational Health Informatics Program, Boston Children's Hospital, Boston, Massachusetts.

Purpose: Research involving adolescent risk behaviors must balance data confidentiality with participant safety when risky behaviors are revealed. This report details a safety protocol and reports the experience of two contemporaneous studies that used it with variant safety thresholds.

Methods: We developed a safety protocol for research with adolescent patients and used it in two concurrent studies of adolescent patients, aged 14-18 years. Read More

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Novel Method to Flag Cardiac Implantable Device Infections by Integrating Text Mining With Structured Data in the Veterans Health Administration's Electronic Medical Record.

JAMA Netw Open 2020 09 1;3(9):e2012264. Epub 2020 Sep 1.

Center for Healthcare Organization and Implementation Research (CHOIR), VA Boston Healthcare System, Boston, Massachusetts.

Importance: Health care-associated infections (HAIs) are preventable, harmful, and costly; however, few resources are dedicated to infection surveillance of nonsurgical procedures, particularly cardiovascular implantable electronic device (CIED) procedures.

Objective: To develop a method that includes text mining of electronic clinical notes to reliably and efficiently measure HAIs for CIED procedures.

Design, Setting, And Participants: In this multicenter, national cohort study using electronic medical record data for patients undergoing CIED procedures in Veterans Health Administration (VA) facilities for fiscal years (FYs) 2016 and 2017, an algorithm to flag cases with a true CIED-related infection based on structured (eg, microbiology orders, vital signs) and free text diagnostic and therapeutic data (eg, procedure notes, discharge summaries, microbiology results) was developed and validated. Read More

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September 2020

Data Acquisition, Processing, and Reduction for Home-Use Trial of a Wearable Video Camera-Based Mobility Aid.

Transl Vis Sci Technol 2020 06 11;9(7):14. Epub 2020 Jun 11.

Schepens Eye Research Institute of Mass Eye & Ear, Boston, MA, USA.

Purpose: Evaluating mobility aids in naturalistic conditions across many days is challenging owing to the sheer amount of data and hard-to-control environments. For a wearable video camera-based collision warning device, we present the methodology for acquisition, reduction, review, and coding of video data for quantitative analyses of mobility outcomes in blind and visually impaired participants.

Methods: Scene videos along with collision detection information were obtained from a chest-mounted collision warning device during daily use of the device. Read More

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Pilot implementation of : A preconception health trial in South Africa.

SAGE Open Med 2020 7;8:2050312120940542. Epub 2020 Jul 7.

South African Medical Research Council/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Objectives: This article describes the learnings from the pilot phase of the Healthy Life Trajectories Initiative, a preconception health trial for 18- to 25-year-old women in Soweto, South Africa.

Methods: The study compares two arms focussed on either physical and mental health (intervention; delivered by community health workers - 'Health Helpers') or standard of care plus (control; standard access to healthcare plus additional telephonic input on 'life skills'; delivered by call centre assistants). These are collectively referred to as . Read More

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Utilization of clinical genetic counseling among childhood and young adult cancer survivors in a registry trial.

J Community Genet 2020 Oct 16;11(4):501-504. Epub 2020 Jul 16.

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

We describe utilization of clinical genetic services among survivors of childhood and young adult cancer after participation in a genetic registry. Clinical genetic counselors flagged 162 out of 1069 pedigrees (15.2%) as suggestive of inheritable cancer susceptibility, resulting in 126 (11. Read More

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October 2020

Accuracy and efficiency of an artificial intelligence tool when counting breast mitoses.

Diagn Pathol 2020 Jul 4;15(1):80. Epub 2020 Jul 4.

Department of Pathology, Samsung Medical Center, Seoul, South Korea.

Background: The mitotic count in breast carcinoma is an important prognostic marker. Unfortunately substantial inter- and intra-laboratory variation exists when pathologists manually count mitotic figures. Artificial intelligence (AI) coupled with whole slide imaging offers a potential solution to this problem. Read More

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GP views on the routine identification of older people living with frailty in primary care.

Br J Gen Pract 2020 Jun;70(suppl 1)

University of Nottingham.

Background: To meet the challenges of an ageing population, the updated 2017/18 NHS GP contract requires primary care providers to use evidence-based frailty identification tools to risk-stratify all patients aged >65 years. Those patients flagged as moderately or severely frail should be clinically reviewed and if severe frailty is confirmed, providers have been asked to consider offering relevant interventions, with the overall aim of enabling these patients to live well for longer. However, there is limited knowledge about how this frailty contractual requirement is being operationalised in primary care. Read More

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"It's Healthy Because It's Natural." Perceptions of "Clean" Eating among U.S. Adolescents and Emerging Adults.

Nutrients 2020 Jun 7;12(6). Epub 2020 Jun 7.

Department of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.

Definitions for the culturally trendy "clean" eating phenomenon vary: whereas some characterize it as natural and healthy, others adopt more restrictive, moralizing, and affectively-laden definitions that may reflect disordered eating. We examined levels of familiarity with "clean" eating, sources of information, and perceptions of this dietary trend among a large, diverse sample of U.S. Read More

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Challenges of Developing a Natural Language Processing Method With Electronic Health Records to Identify Persons With Chronic Mobility Disability.

Arch Phys Med Rehabil 2020 10 21;101(10):1739-1746. Epub 2020 May 21.

Health Policy Research Center, Mongan Institute, Massachusetts General Hospital, Boston, MA; Department of Medicine, Harvard Medical School, Boston, MA. Electronic address:

Objective: To assess the utility of applying natural language processing (NLP) to electronic health records (EHRs) to identify individuals with chronic mobility disability.

Design: We used EHRs from the Research Patient Data Repository, which contains EHRs from a large Massachusetts health care delivery system. This analysis was part of a larger study assessing the effects of disability on diagnosis of colorectal cancer. Read More

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October 2020

Association Between Lifetime Affective Symptoms and Premature Mortality.

JAMA Psychiatry 2020 08;77(8):806-813

MRC Unit for Lifelong Health and Ageing at UCL, University College London, London, United Kingdom.

Importance: Associations between affective symptoms and mortality have been evaluated, but studies have not examined timing or cumulative exposure to affective symptoms over the life course.

Objectives: To examine how lifetime accumulation and timing of affective symptoms are associated with mortality and identify potential explanatory factors.

Design, Setting, And Participants: Data were obtained from the MRC National Survey of Health and Development (1946 British birth cohort), a socially stratified, population-based sample originally consisting of 5362 singleton births in England, Wales, and Scotland during March 1946. Read More

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Validation of the Finnish Health Improvement Profile (HIP) with patients with severe mental illness.

BMC Psychiatry 2020 03 11;20(1):112. Epub 2020 Mar 11.

The Hong Kong Polytechnic University, Hung Hom, Hong Kong.

Background: Physical health among people with severe mental illness (SMI) is a global concern. However, many people with SMI do not receive regular comprehensive health checks. There is currently no validated physical health check instrument systematically used in Finnish mental health services. Read More

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Cost effectiveness of an intervention to increase uptake of hepatitis C virus testing and treatment (HepCATT): cluster randomised controlled trial in primary care.

BMJ 2020 02 26;368:m322. Epub 2020 Feb 26.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK

Objective: To evaluate the effectiveness and cost effectiveness of a complex intervention in primary care that aims to increase uptake of hepatitis C virus (HCV) case finding and treatment.

Design: Pragmatic, two armed, practice level, cluster randomised controlled trial and economic evaluation.

Setting And Participants: 45 general practices in South West England (22 randomised to intervention and 23 to control arm). Read More

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February 2020

Burnout and job satisfaction among Turkish oceangoing seafarers.

Int Marit Health 2019 ;70(4):232-238

Istanbul Technical University, Sahil Cad. Tuzla, Istanbul, Turkey.

Background: Seafaring includes a great variety of stressors that may let seafarers suffer from burnout syndrome. Job satisfaction is one of the most important factors affecting burnout. This study aims to determine the factors that affect job satisfaction and burnout levels of Turkish oceangoing seafarers who work actively on Turkish flagged ships. Read More

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A novel mixed living high training low intervention and the hematological module of the athlete biological passport.

Drug Test Anal 2020 Mar 30;12(3):323-330. Epub 2019 Dec 30.

Aspetar Orthopaedic and Sports Medicine Hospital, Research and Scientific Support, Doha, Ad Dawhah, Qatar.

Exposure to either natural or simulated hypoxia induces hematological adaptations that may affect the parameters of the Athlete Biological Passport (ABP). The aim of the present study was to examine the effect of a novel, mixed hypoxic dose protocol on the likelihood of producing an atypical ABP finding. Ten well-trained middle-distance runners participated in a "live high, train low and high" (LHTLH) altitude training camp for 14 days. Read More

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Measurement invariance of assessments of depression (PHQ-9) and anxiety (GAD-7) across sex, strata and linguistic backgrounds in a European-wide sample of patients after Traumatic Brain Injury.

J Affect Disord 2020 02 31;262:278-285. Epub 2019 Oct 31.

Institute of Medical Psychology and Medical Sociology, University Medical Center, Georg-August-University, Waldweg 37, Eingang A, 37073 Göttingen, Germany.

Background: The Patient Health Questionnaire-9 (PHQ-9) and the Generalized Anxiety Disorder (GAD-7) are two widely used instruments to screen patients for depression and anxiety. Comparable psychometric properties across different demographic and linguistic groups are necessary for multiple group comparison and international research on depression and anxiety.

Objectives And Method: We examine measurement invariance for the PHQ-9 and GAD-7 by: (a) the sex of the participants, (b) recruitment stratum, and (c) linguistic background. Read More

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February 2020

Machine Learning Approaches to Predict 6-Month Mortality Among Patients With Cancer.

JAMA Netw Open 2019 10 2;2(10):e1915997. Epub 2019 Oct 2.

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Importance: Machine learning algorithms could identify patients with cancer who are at risk of short-term mortality. However, it is unclear how different machine learning algorithms compare and whether they could prompt clinicians to have timely conversations about treatment and end-of-life preferences.

Objectives: To develop, validate, and compare machine learning algorithms that use structured electronic health record data before a clinic visit to predict mortality among patients with cancer. Read More

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October 2019

Development and Validation of eRADAR: A Tool Using EHR Data to Detect Unrecognized Dementia.

J Am Geriatr Soc 2020 01 14;68(1):103-111. Epub 2019 Oct 14.

Kaiser Permanente Washington Health Research Institute.

Objectives: Early recognition of dementia would allow patients and their families to receive care earlier in the disease process, potentially improving care management and patient outcomes, yet nearly half of patients with dementia are undiagnosed. Our aim was to develop and validate an electronic health record (EHR)-based tool to help detect patients with unrecognized dementia (EHR Risk of Alzheimer's and Dementia Assessment Rule [eRADAR]).

Design: Retrospective cohort study. Read More

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January 2020