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Prevalence of Common Viral Skin Infections in Beach Volleyball Athletes.

Viruses 2021 Oct 20;13(11). Epub 2021 Oct 20.

Department of Biomedical Sciences, School of Health Sciences, University of West Attica, GR-12243 Athens, Greece.

Viral skin infections often affect the sports community. The aim of this study was to assess the rates, location sites, and seasons of appearance of common viral cutaneous diseases in beach volleyball athletes in Greece. Five hundred and forty-nine beach volleyball athletes participated in this study. Read More

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October 2021

Uncovering Research Trends of Phycobiliproteins Using Bibliometric Approach.

Plants (Basel) 2021 Nov 1;10(11). Epub 2021 Nov 1.

Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Phycobiliproteins are gaining popularity as long-term, high-value natural products which can be alternatives to synthetic products. This study analyzed research trends of phycobiliproteins from 1909 to 2020 using a bibliometric approach based on the Scopus database. The current findings showed that phycobiliprotein is a burgeoning field in terms of publications outputs with "biochemistry, genetics, and molecular biology" as the most related and focused subject. Read More

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November 2021

Development of Oil and Gas Stimulation Fluids Based on Polymers and Recycled Produced Water.

Polymers (Basel) 2021 Nov 20;13(22). Epub 2021 Nov 20.

Advanced Research Center, Saudi Aramco, Dhahran 31311, Saudi Arabia.

Freshwater scarcity is a highly pressing and accelerating issue facing our planet. Therefore, there is a great incentive to develop sustainable solutions by reusing wastewater or produced water (PW), especially in places where it is generated abundantly. PW represents the water produced as a by-product during oil and gas extraction operations in the petroleum industry. Read More

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November 2021

Clinical Predictors of Mortality in Prehospital Distress Calls by Emergency Medical Service Subscribers.

J Clin Med 2021 Nov 17;10(22). Epub 2021 Nov 17.

Hadassah Medical Center, Cardiology Department, Faculty of Medicine, Hebrew University Jerusalem, Jerusalem 91905, Israel.

(1) Introduction: Most studies rely on in-hospital data to predict cardiovascular risk and do not include prehospital information that is substantially important for early decision making. The aim of the study was to define clinical parameters in the prehospital setting, which may affect clinical outcomes. (2) Methods: In this population-based study, we performed a retrospective analysis of emergency calls that were made by patients to the largest private emergency medical services (EMS) in Israel, SHL Telemedicine Ltd. Read More

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November 2021

Brief Report of Anti-Programmed Cell Death Protein-1 in Human Immunodeficiency Virus Setting: Relevant and Breaking Results in First-Line NSCLC Therapy.

JTO Clin Res Rep 2021 Nov 26;2(11):100247. Epub 2021 Oct 26.

Service de Pneumologie et Oncologie Thoracique, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris (APHP), Sorbonne Université, Paris, France.

In the recent past, we observed an increased risk of cancer in the population with human immunodeficiency virus (HIV) owing to the development of antiretroviral therapies that decreased mortality caused by HIV-specific infections. This particularly fragile population is frequently excluded from clinical trials, and up-to-date recommendations for these patients are lacking. Only few cases of patients with HIV suffering from cancer and undergoing first-line immunotherapy have been reported so far. Read More

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November 2021

Hematological, Micro-Rheological, and Metabolic Changes Modulated by Local Ischemic Pre- and Post-Conditioning in Rat Limb Ischemia-Reperfusion.

Metabolites 2021 Nov 13;11(11). Epub 2021 Nov 13.

Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Moricz Zsigmond u. 22, H-4002 Debrecen, Hungary.

In trauma and orthopedic surgery, limb ischemia-reperfusion (I/R) remains a great challenge. The effect of preventive protocols, including surgical conditioning approaches, is still controversial. We aimed to examine the effects of local ischemic pre-conditioning (PreC) and post-conditioning (PostC) on limb I/R. Read More

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November 2021

Controllability and state feedback control of a cardiac ionic cell model.

Comput Biol Med 2021 Sep 30;139:104909. Epub 2021 Sep 30.

School of Mathematical Sciences, Rochester Institute of Technology, Rochester, NY, 14623, USA. Electronic address:

A phenomenon called alternans, which is a beat-to-beat alternation in action potential (AP) duration, sometimes precedes fatal cardiac arrhythmias. Alternans-suppressing electrical stimulus protocols are often represented as perturbations to the dynamics of membrane potential or AP duration variables in nonlinear models of cardiac tissue. Controllability analysis has occasionally been applied to cardiac AP models to determine whether different control or perturbation strategies are capable of suppressing alternans or other unwanted behavior. Read More

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September 2021

A bibliometric analysis of the top 100 most-cited case reports and case series in Endodontic journals.

Int Endod J 2021 Nov 24. Epub 2021 Nov 24.

School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.

Aim: To identify the top 100 most-cited case reports and case series published in Endodontic journals and to analyse their bibliometric characteristics.

Methodology: The Clarivate Analytics' Web of Science (WoS), Scopus, and PubMed databases were used to identify the top 100 most-cited case reports and case series in Endodontic journals. Complete bibliographic records of the selected case reports and case series were exported in plain text or BibTeX format and imported into the R environment for statistical computing and graphics. Read More

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November 2021

[Study of morphometric parameters of the hyoid bone].

Sud Med Ekspert 2021 ;64(6):34-38

Tver Institute of the Moscow Humanitarian Economic University, Tver, Russia.

The Objective Of The Work: Is to study the morphological and morphometric variations of the hyoid bone in the population of the Tver region. One hundred adult hyoid bone samples were taken from 63 males and 37 females. Morphological and morphometric variations of the hyoid bone were determined. Read More

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November 2021

Gestational Age and Neonatal Electrocardiograms.

Pediatrics 2021 Nov 24. Epub 2021 Nov 24.

Department of Cardiology, Herlev-Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.

Objectives: Interpretation of the neonatal electrocardiogram (ECG) is challenging due to the profound changes of the cardiovascular system in this period. We aimed to investigate the impact of gestational age (GA) on the neonatal ECG and create GA-specific reference values.

Methods: The Copenhagen Baby Heart Study is a prospective general population study that offered cardiac evaluation of neonates. Read More

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November 2021

The effect of horseshoes and surfaces on horse and jockey centre of mass displacements at gallop.

PLoS One 2021 23;16(11):e0257820. Epub 2021 Nov 23.

The Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom.

Horseshoes influence how horses' hooves interact with different ground surfaces, during the impact, loading and push-off phases of a stride cycle. Consequently, they impact on the biomechanics of horses' proximal limb segments and upper body. By implication, different shoe and surface combinations could drive changes in the magnitude and stability of movement patterns in horse-jockey dyads. Read More

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November 2021

Application of nonlinear analysis for the assessment of gait in patients with Parkinson's disease.

Technol Health Care 2021 Nov 12. Epub 2021 Nov 12.

Background: Gait can be affected by diseases such as Parkinson's disease (PD), which lead to alterations like shuffle gait or loss of balance. PD diagnosis is based on subjective measures to generate a score using the Unified Parkinson's Disease Rating Scale (UPDRS). To improve clinical assessment accuracy, gait analysis can utilise linear and nonlinear methods. Read More

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November 2021

Computational analysis of aortic haemodynamics in the presence of ascending aortic aneurysm.

Technol Health Care 2021 Nov 12. Epub 2021 Nov 12.

Department of Biomechanical Engineering, Faculty of Mechanics, Vilnius Gediminas Technical University, Vilnius, Lithuania.

Background: The usefulness of numerical modelling of a patient's cardiovascular system is growing in clinical treatment. Understanding blood flow mechanics can be crucial in identifying connections between haemodynamic factors and aortic wall pathologies.

Objective: This work investigates the haemodynamic parameters of an ascending aorta and ascending aortic aneurysm in humans. Read More

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November 2021

Assessment and Prognostic Value of Immediate Changes in Post-Ablation Intratumor Density Heterogeneity of Pulmonary Tumors Radiomics-Based Computed Tomography Features.

Front Oncol 2021 3;11:615174. Epub 2021 Nov 3.

Department of Radiation Oncology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Objectives: To retrospectively observe the instantaneous changes in intratumor density heterogeneity after microwave ablation (MWA) of lung tumors and to determine their prognostic value in predicting treatment response and local tumor progression (LTP).

Methods: Pre- and post-MWA computed tomography (CT) images of 50 patients (37-males; 13-females; mean-age 65.9 ± 9. Read More

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November 2021

The Value of Thromboelastography (TEG) in COVID-19 Critical Illness as Illustrated by a Case Series.

J Cardiothorac Vasc Anesth 2021 Oct 16. Epub 2021 Oct 16.

Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Vice Chair for Academic Affairs, Director, Cardiovascular Anesthesiology, 300 Community Drive, Manhasset, NY, 11030. Electronic address:

Objective: To develop a practical thromboelastograph guided (TEG) anticoagulation protocol to guide the management of COVID-19 critically ill patients.

Design: An inter disciplinary team reviewed the current literature on hypercoagulability in critically ill COVID-19 patients, clinical management practices and challenges with high rates of thrombotic events despite anticoagulant therapies.

Setting: The largest tertiary care hospital within the Northwell Health System in New York. Read More

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October 2021

Data science approaches to confronting the COVID-19 pandemic: a narrative review.

Philos Trans A Math Phys Eng Sci 2022 Jan 22;380(2214):20210127. Epub 2021 Nov 22.

The State Key Laboratory of Management and Control for Complex Systems, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, People's Republic of China.

During the COVID-19 pandemic, more than ever, data science has become a powerful weapon in combating an infectious disease epidemic and arguably any future infectious disease epidemic. Computer scientists, data scientists, physicists and mathematicians have joined public health professionals and virologists to confront the largest pandemic in the century by capitalizing on the large-scale 'big data' generated and harnessed for combating the COVID-19 pandemic. In this paper, we review the newly born data science approaches to confronting COVID-19, including the estimation of epidemiological parameters, digital contact tracing, diagnosis, policy-making, resource allocation, risk assessment, mental health surveillance, social media analytics, drug repurposing and drug development. Read More

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January 2022

Effect of Intramedullary Nailing Patterns On Interfragmentary Strain in a Mouse Femur Fracture: a Parametric Finite Element Analysis.

J Biomech Eng 2021 Nov 21. Epub 2021 Nov 21.

Vanderbilt University, Department of Biomedical Engineering, 5824 Stevenson Center, Nashville, TN 37232, USA; Vanderbilt University Medical Center, Department of Orthopaedic Surgery, 1215 21st Ave. S., Suite 4200, Nashville, TN 37232; Vanderbilt University Medical Center, Vanderbilt Center for Bone Biology, 1211 Medical Center Dr., Nashville, TN 37212; Vanderbilt University Medical Center, Department of Medicine, 1211 Medical Center Dr., Nashville, TN 37217.

Delayed long bone fracture healing and nonunion continue to be a significant socioeconomic burden. While mechanical stimulation is known to be an important determinant of the bone repair process, understanding how the magnitude, mode, and commencement of interfragmentary strain (IFS) affect fracture healing can guide new therapeutic strategies to prevent delayed healing or non-union. Mouse models provide a means to investigate the molecular and cellular aspects of fracture repair, yet there is only one commercially available, clinically-relevant, locking intramedullary nail (IMN) currently available for studying long bone fractures in rodents. Read More

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November 2021

Mechanical failure of posterior teeth due to caries and occlusal wear- A modelling study.

J Mech Behav Biomed Mater 2021 Oct 29;125:104942. Epub 2021 Oct 29.

School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW, 2006, Australia. Electronic address:

Objectives: The purpose of the present work is to explore the effect of occlusal wear and different types and degrees of caries on the mechanical performance and structural integrity of posterior teeth.

Methods: Three-dimensional (3D) computational models with different combinations of caries parameters (caries location, caries size and caries induced pulp shrinkage) and occlusal wear factors (enamel thickness, marginal ridge height and cuspal slope) were developed and analyzed using the extended finite element method (XFEM) to identify the stress distribution, crack initiation load and ultimate fracture load values. The effect of a non-drilling conservative treatment using resin infiltration on the recovery of mechanical properties of carious molar teeth was also investigated. Read More

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October 2021

Establishment of a multi-parameters MRI model for predicting small lymph nodes metastases (<10 mm) in patients with resected pancreatic ductal adenocarcinoma.

Abdom Radiol (NY) 2021 Nov 20. Epub 2021 Nov 20.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, No.52 Fu Cheng Road, Hai Dian District, Beijing, 100142, China.

Purpose: To evaluate the potential role of MR findings and DWI parameters in predicting small regional lymph nodes metastases (with short-axis diameter < 10 mm) in pancreatic ductal adenocarcinomas (PDACs).

Methods: A total of 127 patients, 82 in training group and 45 in testing group, with histopathologically diagnosed PDACs who underwent pancreatectomy were retrospectively analyzed. PDACs were divided into two groups of positive and negative lymph node metastases (LNM) based on the pathological results. Read More

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November 2021

Confidence of UK Ophthalmology Registrars in Managing Posterior Capsular Rupture: Results from a National Trainee Survey.

Ophthalmol Ther 2021 Nov 19. Epub 2021 Nov 19.

Department of Ophthalmology, Musgrove Park Hospital, Parkfield Drive, Taunton, TA1 5DA, Somerset, UK.

Introduction: To establish the level of confidence amongst UK ophthalmology specialist registrars (residents) in managing posterior capsule rupture (PCR) during cataract surgery.

Methods: An online nine-item questionnaire was distributed to all registrars, recruited nationwide via regional representatives. Data collected included stage of training, number of completed cataract operations, cumulative PCR rate, number of PCRs independently managed, understanding of vitrectomy settings and fluidic parameters and access to simulation. Read More

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November 2021

Intervening on psychopathology networks: Evaluating intervention targets through simulations.

Methods 2021 Nov 15. Epub 2021 Nov 15.

Department of Psychological Methods, University of Amsterdam, Amsterdam, The Netherlands.

Identifying the different influences of symptoms in dynamic psychopathology models may hold promise for increasing treatment efficacy in clinical applications. Dynamic psychopathology models study the behavioral patterns of symptom networks, where symptoms mutually enforce each other. Interventions could be tailored to specific symptoms that are most effective at lowering symptom activity or that hinder the further development of psychopathology. Read More

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November 2021

Colon capsule endoscopy in colorectal cancer screening: Interim analyses of randomized controlled trial CareForColon2015.

Endosc Int Open 2021 Nov 12;9(11):E1712-E1719. Epub 2021 Nov 12.

Department of Surgery, Odense University Hospital, Svendborg, Denmark.

 The Danish CareForColon2015 trial, launched in 2020 as part of the Danish Colorectal Cancer Screening program, is the largest randomized controlled trial to date on colon capsule endoscopy (CCE). This paper presents the interim analysis with the objective of ensuring the safety of patients in the intervention group and evaluating the clinical performance of the trial's predefined clinical parameters.  We evaluated the initial 234 CCEs according to quality, safety, and completion. Read More

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November 2021

Efficacy of bowel preparation regimens for colon capsule endoscopy: a systematic review and meta-analysis.

Endosc Int Open 2021 Nov 12;9(11):E1658-E1673. Epub 2021 Nov 12.

Department of Gastroenterology, Skåne University Hospital, Malmö, Lund University, Sweden.

Colon capsule endoscopy (CCE) is an alternative to conventional colonoscopy (CC) in specific clinical settings. High completion rates (CRs) and adequate cleanliness rates (ACRs) are fundamental quality parameters if CCE is to be widely implemented as a CC equivalent diagnostic modality. We conducted a systematic review and meta-analysis to investigate the efficacy of different bowel preparations regimens on CR and ACR in CCE. Read More

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November 2021

Comparison of player-dependent and independent high-speed running thresholds to model injury risk in football.

J Sports Sci 2021 Nov 18:1-8. Epub 2021 Nov 18.

School of Health Sciences, Western Sydney University, Richmond, Australia.

High-speed running (HSR) loads have been linked with non-contact injury risks in team-sports. This study investigated whether player-specific speed zones, reflecting individual fitness characteristics, impact the associations between non-contact injury and acute and chronic HSR loads. Semi-professional soccer players from two clubs (n = 47) were tracked over two seasons using 10 Hz GPS (5552 observations). Read More

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November 2021

The EQ-5D-5L Valuation Study in Egypt.

Pharmacoeconomics 2021 Nov 17. Epub 2021 Nov 17.

Department of Clinical Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.

Introduction: No value sets exist for either the EQ-5D-3L or the EQ-5D-5L in Egypt, despite local pharmacoeconomic guidelines recommending the use of the EQ-5D to derive utility. Most published Egyptian economic evaluation studies have used utility values from other published studies and systematic reviews.

Objective: Our objective was to develop an Egyptian EQ-5D-5L value set using the international EuroQol standardized protocol (EQ-VT-2. Read More

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November 2021

Effectiveness of a body shape index in predicting pediatric high blood pressure.

Pediatr Res 2021 Nov 16. Epub 2021 Nov 16.

Suzhou Center for Disease Prevention and Control, Suzhou, Jiangsu, China.

Background: A body shape index (ABSI) is an emerging anthropometric indicator, challenging two traditional parameters: body mass index (BMI) and waist circumference (WC). We aimed to systematically compare and validate the capability of anthropometric indicators for determining pediatric high blood pressure (HBP).

Methods: A total of 3150 participants aged 7-17 years were enrolled from Suzhou, China. Read More

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November 2021

Effect of biostimulants on the growth, yield and nutritional value of Capsicum annuum grown in an unheated plastic tunnel.

Sci Rep 2021 Nov 16;11(1):22335. Epub 2021 Nov 16.

Department of Agroecosystems and Horticulture, Faculty of Agriculture and Forestry, University of Warmia and Mazury in Olsztyn, Plac Łódzki 3, 10-718, Olsztyn, Poland.

Recent years have witnessed an increased interest in the cultivation and consumption of peppers. Therefore, new solutions are being sought to provide pepper plants with the most favorable conditions for growth and development. In view of the above, the aim of this study was to evaluate the effect of selected biostimulants on the biometric parameters, yield and nutritional value of Capsicum annuum fruit. Read More

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November 2021

Postpartum septic symphysitis, a rare condition with possible long-term consequences: a cohort study with long-term follow-up.

BMC Pregnancy Childbirth 2021 Nov 16;21(1):776. Epub 2021 Nov 16.

Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.

Background: Postpartum septic symphysitis (PPSS) is defined as acute onset of severe pain around the symphysis, restricted movement, fever, and elevated inflammatory parameters. It is a rare but serious condition requiring urgent diagnosis and treatment. The aim of this study was to describe the incidence, symptoms, diagnosis, treatment, and long-term follow-up of PPSS. Read More

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November 2021

Replication of Reduced Pattern Electroretinogram Amplitudes in Depression With Improved Recording Parameters.

Front Med (Lausanne) 2021 29;8:732222. Epub 2021 Oct 29.

Department of Psychiatry and Psychotherapy, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

The retina has gained increasing attention in non-ophthalmological research in recent years. The pattern electroretinogram (PERG), a method to evaluate retinal ganglion cell function, has been used to identify objective correlates of the essentially subjective state of depression. A reduction in the PERG contrast gain was demonstrated in patients with depression compared to healthy controls with normalization after remission. Read More

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October 2021

Effects of intervalence charge transfer interaction between π-stacked mixed valent tetrathiafulvalene ligands on the electrical conductivity of 3D metal-organic frameworks.

Chem Sci 2021 Oct 20;12(40):13379-13391. Epub 2021 Sep 20.

Department of Chemistry, Clemson University Clemson South Carolina 29634 USA

Achieving a molecular-level understanding of how the structures and compositions of metal-organic frameworks (MOFs) influence their charge carrier concentration and charge transport mechanism-the two key parameters of electrical conductivity-is essential for the successful development of electrically conducting MOFs, which have recently emerged as one of the most coveted functional materials due to their diverse potential applications in advanced electronics and energy technologies. Herein, we have constructed four new alkali metal (Na, K, Rb, and Cs) frameworks based on an electron-rich tetrathiafulvalene tetracarboxylate (TTFTC) ligand, which formed continuous π-stacks, albeit with different π-π-stacking and S⋯S distances ( and ). These MOFs also contained different amounts of aerobically oxidized TTFTC˙ radical cations that were quantified by electron spin resonance (ESR) spectroscopy. Read More

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October 2021