9,786 results match your criteria papilloma virus

Nurses' and teachers' perceived barriers and facilitators to the uptake of the Human Papilloma Virus (HPV) vaccination program in Iquitos, Peru: A qualitative study.

PLoS One 2021 29;16(7):e0255218. Epub 2021 Jul 29.

Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.

Globally, over 300,000 women die of cervical cancer annually. Given that human papillomavirus vaccines are highly effective in the primary prevention of cervical cancer, it is important to explore the barriers and facilitators to vaccination uptake in areas where the burden of disease remains high. This study, informed by the socio-ecological model, aimed to qualitatively explore vaccination uptake via in-depth interviews with eleven nurses and ten teachers involved in vaccine delivery in Iquitos, Peru. Read More

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A descriptive study of the clinical and etiological profile of balanoposthitis.

J Family Med Prim Care 2021 Jun 2;10(6):2265-2271. Epub 2021 Jul 2.

Department of Dermatology, S. R. M Medical College Hospital and Research Centre, Potheri, Chennai, Tamilnadu, India.

Background: Balanoposthitis is defined as an inflammatory condition of glans penis and prepuce. There are wide variety of etiologies including both infectious and noninfectious conditions. This study attempts to throw light on information regarding clinical and microbiological aspects of balanoposthitis. Read More

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The genetic diversity of "papillomavirome" in bovine teat papilloma lesions.

Anim Microbiome 2021 Jul 28;3(1):51. Epub 2021 Jul 28.

Laboratório de Microbiologia Molecular, Instituto de Ciências da Saúde, Universidade Feevale, Novo Hamburgo, RS, Brazil.

Background: Papillomaviruses are small nonenveloped, circular double-stranded DNA viruses that belong to the Papillomaviridae family. To date, 29 Bos taurus papillomavirus (BPV) types have been described. Studies involving mixed BPV infections have rarely been reported in contrast to human papillomavirus (HPV), which is commonly described in numerous studies showing coinfections. Read More

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Prevalence of Abnormal Anal Cytology in Women with Abnormal Cervical Cytology.

Asian Pac J Cancer Prev 2021 Jul 1;22(7):2165-2169. Epub 2021 Jul 1.

Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok, Thailand.

Objective: The aim of this study was to evaluate the prevalence of abnormal anal cytology in women presenting with abnormal cervical cytology (intraepithelial lesion or cervical cancer) at the largest tertiary university hospital in Thailand.

Methods: A cross-sectional prospective study design was used. Anal cytology was performed on 145 women with abnormal cervical cytology between June 2014-Octoble 2014. Read More

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Human Papilloma Virus Distribution Across the African Diaspora.

JCO Glob Oncol 2021 Jul;7:1206-1208

Division of Gynecologic Oncology, Sylvester Comprehensive Cancer Center, MI.

Purpose: Understanding the distribution of human papilloma virus (HPV) subtypes in limited-resource settings is imperative for cancer prevention strategies in these regions. The objective of our study is to compare the prevalence of cervical HPV genotypes in women across the African diaspora.

Methods: This study was approved by the African Caribbean Consortium (AC3). Read More

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Triple signal amplification strategy for the ultrasensitive electrochemical detection of human papillomavirus 16 E6/E7 mRNA.

Enzyme Microb Technol 2021 Sep 19;149:109855. Epub 2021 Jun 19.

State Key Laboratory of Pharmaceutical Biotechnology, Department of Rheumatology and Immunology, The Affiliated Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, China. Electronic address:

Human papilloma virus (HPV) is the primary causative agent of cervical, vaginal, and vulvar cancers. HPV E6/E7 mRNA detection has been proven to improve the specificity and positive predictive value compared with HPV DNA testing in screening, whereby, it may possess higher diagnostic potential. Herein, to establish the ultrasensitive and specific detection of HPV E6/E7 mRNA, we developed a novel triple signal amplification strategy, combined with gold nanoparticles (AuNPs), reverse transcription loop-mediated isothermal amplification (RT-LAMP) and high affinity biotin-avidin system. Read More

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September 2021

Information seeking behaviour differences indicate which US population groups lack information about human papilloma virus and associated cancer risks.

Bahareh Ansari

Health Info Libr J 2021 Jul 23. Epub 2021 Jul 23.

Department of Information Science, University at Albany-State University of New York, Albany, New York, USA.

Background: The majority of the US population have poor knowledge of cancers related to human papillomavirus (HPV). Identifying best sources for communicating this information can guide strategies to promote HPV vaccination.

Objectives: To assess the relationship between sources of health information and individuals' knowledge of HPV-related cervical and oropharyngeal cancer. Read More

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Assessing the Feasibility of Adapting a School-Based HIV Prevention Intervention to Include Voluntary Male Medical Circumcision and Vaccination for Human Papilloma Virus Prevention.

East Afr Health Res J 2020 26;4(1):108-112. Epub 2020 Jun 26.

Kenya Medical Research Institute Centre for Global Health Research, Kisumu, Kenya.

In 2012, there were 2,454 cases and 1,676 deaths from cervical cancer in Kenya. Human Papilloma Virus (HPV) is responsible for 99% of all cervical cancers. National cervical cancer prevention guidelines recommend HPV vaccination among HPV-naïve pre-adolescent girls' prior to onset of sexual activity preferably through school-based interventions. Read More

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Topical tirbanibulin eradication of periungual squamous cell carcinoma.

JAAD Case Rep 2021 Aug 26;14:101-103. Epub 2021 Jun 26.

Arlington Research Center, Arlington, Texas.

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Giant Condyloma Acuminata (Buschke-Lowenstein Tumor): Review of an Unusual Disease and Difficult to Manage.

Infect Dis Obstet Gynecol 2021 30;2021:9919446. Epub 2021 Jun 30.

Oncology Surgery Department, Hospital Regional de Alta Especialidad del Bajío, León, Guanajuato, Mexico.

Giant condyloma acuminatum (GCA) or Buschke-Loewenstein tumor is a rare disease, with an estimated prevalence of 0.1%. It was initially described in 1896 by Buschke and later in 1925 by Buschke and Loewenstein. Read More

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The impact of HPV vaccination on the prevention of oropharyngeal cancer: A scoping review.

Community Dent Health 2021 Jul 15. Epub 2021 Jul 15.

Centre for Dental Public Health and Primary Care, Queen Mary University London, United Kingdom.

Introduction: HPV-associated oropharyngeal cancer (OPC) has one of the most rapidly rising incidences of any cancer in high-income countries. HPV vaccination is being tested to prevent HPV-associated OPC.

Objective: To determine the effect of Human Papilloma Virus (HPV) vaccination on the prevention of OPC in adults worldwide. Read More

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HPV 16 and 18 contribute to development of anal dysplasia in HIV infection irrespective of gender and sexual orientation.

HIV Med 2021 Jul 22. Epub 2021 Jul 22.

Infectious Diseases Unit, Azienda Socio Sanitaria Territoriale (ASST) Monza, San Gerardo Hospital, Monza, Italy.

Objectives: The aim of the present study was too investigate prevalence and persistence of human papilloma virus (HPV) and cytological abnormalities (CAs) in the anal swabs of people living with HIV (PLWH): men who have sex with men (MSM), men who have sex with women (MSW) and women (W).

Methods: Between March 2010 and January 2019, an anal swab for cytological and HPV genotyping tests was offered to all PLWH attending our clinic. Logistic regression analysis was conducted to identify predictors of infection. Read More

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An Immune-Gene-Based Classifier Predicts Prognosis in Patients With Cervical Squamous Cell Carcinoma.

Front Mol Biosci 2021 5;8:679474. Epub 2021 Jul 5.

Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Immunity plays a vital role in the human papilloma virus (HPV) persistent infection, and closely associates with occurrence and development of cervical squamous cell carcinoma (CSCC). Herein, we performed an integrated bioinformatics analysis to establish an immune-gene signature and immune-associated nomogram for predicting prognosis of CSCC patients. The list of immunity-associated genes was retrieved from ImmPort database. Read More

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Infection and food combine to cause atherosclerotic coronary heart disease - Review and hypothesis.

Int J Cardiol Heart Vasc 2021 Aug 6;35:100807. Epub 2021 Jul 6.

School of Biotechnology and Biomolecular Science, University of New South Wales, Sydney, NSW 2052, Australia.

Hypothesis: It is hypothesised that a combination of childhood and later life infections and excess food consumption, particularly of Western style food, initiates and contributes to atherosclerotic coronary heart disease. To consider this hypothesis we have conducted a brief review of the role of childhood infections, food, and their combined influence on atherosclerosis.

Evidence: (i) Studies of populations with high prevalence of infections and low "hunter gather" like food consumption, have extremely low prevalence of atherosclerosis, (ii) there are consistent associations between infections in childhood and adult atherosclerotic coronary heart disease, (iii) there is an association between increased body weight, (an indication of excess eating), and atherosclerotic heart disease, and (iv) there is evidence that a combination of increased body weight and infections influences the development of atherosclerotic coronary heart disease. Read More

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Human papilloma virus: A review study of epidemiology, carcinogenesis, diagnostic methods, and treatment of all HPV-related cancers.

Med J Islam Repub Iran 2021 22;35:65. Epub 2021 May 22.

Cellular and Molecular Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Human papillomavirus (HPV) infection is considered as the most common viral sexually transmitted infection worldwide. This poses an increasingly interdisciplinary medical challenge. Since there is vast scattered information in databases about HPV and the correlated diseases, we decided to collect useful data so that the experts can get a more comprehensive view of HPV. Read More

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Human papillomavirus in breast cancer of patients with cervical intraepithelial neoplasia or cervical cancer history. A systematic review and meta-analysis.

J BUON 2021 May-Jun;26(3):707-713

2nd Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece.

Purpose: Many cohort studies and meta-analyses support the oncogenic role of the human papilloma virus (HPV) on breast tissue. However, only a few studies examine the association between HPV-positive breast cancer and the prior history of high grade cervical intraepithelial neoplasia (CIN) or cervical cancer. The present systematic review and meta-analysis aimed to determine whether women with a history of high grade CIN or cervical cancer are at a higher risk of developing HPV-positive breast cancer. Read More

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Risk factors of cervical cancer among ethnic minorities in Yunnan Province, China: a case-control study.

Eur J Cancer Prev 2021 Jul 20. Epub 2021 Jul 20.

Medical Administration Department, The Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital), Xi Shan county School of Public Health, Kunming Medical University, Cheng Gong New City Department of Gynecology, The Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital), Xi Shan county, Kunming, Yunnan, China.

Background: Cervical cancer is a common malignant tumor of the female reproductive system in the world, which is a serious threat to women's life and health. According to the latest report, the incidence of cervical cancer is 11.42 per 100 000, and the mortality rate is 3. Read More

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The prevalence and genotype distribution of human papilloma virus in cervical squamous intraepithelial lesion and squamous cell carcinoma in Taizhou, China.

Medicine (Baltimore) 2021 Jul;100(28):e26593

Department of Pathology, Taizhou People's Hospital Affiliated to Dalian Medical University, Taizhou, Jiangsu, China.

Abstract: Human papillomavirus (HPV) infection is a common sexually transmitted disease worldwide and the leading cause of cervical cancer. Current vaccines do not cover all HPV genotypes whereas the distribution of HPV genotypes varies in different geographic regions. The study aimed to investigate the distribution of HPV genotypes in patients with cervical squamous intraepithelial lesion (SIL) and cervical squamous cell carcinoma (SCC) in Taizhou City of Jiangsu Province, China. Read More

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Lower disease control rates and survival outcomes among Blacks with pharyngeal squamous cell carcinomas compared with Whites: a retrospective analysis at the University of Florida.

Cancer Causes Control 2021 Jul 14. Epub 2021 Jul 14.

Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, USA.

Disparate clinical outcomes for pharyngeal squamous cell carcinoma (PSCC) of the oropharynx (OPSCC) and hypopharynx (HPSCC) have been observed in Black compared with White patients. Higher tobacco and alcohol use has been associated with decreased survival in Black patients with PSCC. Higher human papilloma virus (HPV) infection rates, associated with specific subsites of the oropharynx, are linked to improved overall survival (OS). Read More

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No family should suffer from cervical cancer twice - the palliative care role in HPV prevention.

J Pain Symptom Manage 2021 Jul 10. Epub 2021 Jul 10.

Hospice and Palliative Care, Veterans Administration Medical Center, Iowa City, Iowa, USA.

Context: Cervical cancer, caused by human papillomavirus (HPV) infection, is the source of significant personal and societal burden, and robs more than one hundred thousand Indian women and their families of the chances of a healthy and productive life each year. As outlined by the World Health Organization (WHO), the three-pronged approach of screening, vaccination, and reduction in mortality by early treatment presents the possibility of the elimination of cervical cancer as a public health problem in the next decade (1). Unfortunately, these approaches are all associated with significant barriers in India. Read More

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The Role of Human Papilloma Virus in Dictating Outcomes in Head and Neck Squamous Cell Carcinoma.

Front Mol Biosci 2021 23;8:677900. Epub 2021 Jun 23.

School of Medicine, Faculty of Health Sciences, Trinity College, Dublin, Ireland.

The Human Papilloma Virus (HPV) is an oncogenic virus which is associated with the development of head and neck squamous cell carcinoma (HNSCC), predominantly within the oropharynx. Approximately 25% of oropharyngeal squamous cell carcinoma (OPSCC) cases worldwide are attributable to HPV infection, with an estimated 65% in the United States. Transmission is exposure during sexual contact, with distinctive anatomical features of the tonsils providing this organ with a predilection for infection by HPV. Read More

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Alpelisib and radiotherapy treatment enhances Alisertib-mediated cervical cancer tumor killing.

Am J Cancer Res 2021 15;11(6):3240-3251. Epub 2021 Jun 15.

Menzies Health Institute Queensland and School of Medical Science, School of Medical Science, Griffith University Southport, Queensland, Australia.

Human papilloma virus (HPV) is the main causative agent in cervical cancers. High-risk HPV cancers, including cervical cancer, are driven by major HPV oncogene, E6 and E7, which promote uncontrolled cell growth and genomic instability. We have previously shown that the presence of HPV E7 sensitizes cells to inhibition of aurora kinases (AURKs), which regulates the control of cell entry into and through mitosis. Read More

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Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor.

Aging (Albany NY) 2021 07 11;13(13):17789-17817. Epub 2021 Jul 11.

Department of Dental Implant Center, Stomatologic Hospital and College, Anhui Medical University, Key Laboratory of Oral Diseases Research of Anhui Province, Hefei 230032, China.

Chemokines play a significant role in cancer. CXC-motif chemokine ligands (CXCLs) are associated with the tumorigenesis and progression of head and neck squamous cell carcinoma (HNSC); however, their specific functions in the tumor microenvironment remain unclear. Here, we analyzed the molecular networks and transcriptional data of HNSC patients from the Oncomine, GEPIA, String, cBioPortal, Metascape, TISCH, and TIMER databases. Read More

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Immunotherapy for Head and Neck Cancer.

Hematol Oncol Clin North Am 2021 Jul 6. Epub 2021 Jul 6.

Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania, Perelman Center for Advanced Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address:

Head and neck squamous cell carcinomas (HNSCC) remain an important cause of global cancer morbidity and mortality. Historically, outcomes for patients with recurrent or metastatic disease were poor with limited treatment options. In recent decades, the demographic profile of this disease has evolved with an increase in human papilloma virus-associated oropharyngeal carcinoma and a decrease in tobacco-related disease. Read More

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Physiologic and molecular characterization of a novel murine model of metastatic head and neck cancer cachexia.

J Cachexia Sarcopenia Muscle 2021 Jul 6. Epub 2021 Jul 6.

Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR, USA.

Background: Cancer cachexia is a metabolic disorder characterized by the progressive loss of fat and lean mass that results in significant wasting, ultimately leading to reduced quality of life and increased mortality. Effective therapies for cachexia are lacking, potentially owing to the mismatch in clinically relevant models of cachexia. Specifically, cachexia observed in a clinical setting is commonly associated with advanced or late-stage cancers that are metastatic, yet pre-clinical metastatic models of cachexia are limited. Read More

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The efficacy of vaccination to prevent human papilloma viruses infection at anal and oral: a systematic review and meta-analysis.

Public Health 2021 Jul 3;196:165-171. Epub 2021 Jul 3.

Medical Laboratory, Liang Ping People's Hospital of Chongqing, Liangping, 405200, Chongqing City, China. Electronic address:

Objective: The objective of this study was to review evidence on the effectiveness of vaccination in the prevention of human papilloma virus (HPV) infection at the cervix, anal, and oral.

Study Design: Systematic review and meta-analysis.

Methods: The key search limitations are as follows: "Human Papilloma Virus", "Papilloma Virus, Human" "Human Papillomavirus Virus", "HPV" and "oral", "anus", "anal", "penis", "cervical," and "vaccine". Read More

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[Quantitative analysis of nine types of virus-like particles in human papilloma virus bulk by size-exclusion chromatography].

Se Pu 2021 Apr;39(4):424-429

National Institutes for Food and Drug Control, Key Laboratory of National Health Commission for Research on Quality and Standardization of Biotech Products, Key Laboratory of Biological Product Quality Research and Evaluation of National Medical Products Administration, Beijing 102629, China.

Cervical cancer is the fourth most common cancer among women. Human papilloma virus (HPV) is the most common cause of cervical cancer which accounts for 5% of all human cancers and results in about 528000 cases and 266000 deaths every year. HPV vaccines are considered the most effective strategy for the prevention of HPV infection and cervical carcinoma. Read More

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A 25-year perspective on advances in an understanding of the biology, evaluation, treatment and future directions/challenges of penile cancer.

Urol Oncol 2021 Jul 1. Epub 2021 Jul 1.

Division of Hematology & Medical Oncology, Department of Medicine and Department of Urology, Weill Cornell Medicine, New York, NY. Electronic address:

Squamous cell carcinoma of the penis (SCCP) is uncommon in some countries (including the U.S.), but is an important malignancy elsewhere. Read More

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Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy.

Cell 2021 Jul 1;184(14):3812-3828.e30. Epub 2021 Jul 1.

Zahedan University of Medical Sciences, 054 Zahedan, Iran.

We study a patient with the human papilloma virus (HPV)-2-driven "tree-man" phenotype and two relatives with unusually severe HPV4-driven warts. The giant horns form an HPV-2-driven multifocal benign epithelial tumor overexpressing viral oncogenes in the epidermis basal layer. The patients are unexpectedly homozygous for a private CD28 variant. Read More

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Acquired epidermodysplasia verruciformis or generalized verrucosis? A clinical and virological comparative study.

J Dermatol 2021 Jul 2. Epub 2021 Jul 2.

Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Few articles have described the difference between epidermodysplasia verruciformis (EV) and generalized verrucosis (GV). This study aimed to analyze the clinical findings and virology of the two diseases. The study enrolled patients diagnosed with EV and GV by clinical and histopathological findings. Read More

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