11,503 results match your criteria pap test

Multiple Consecutive Cervicovaginal Cytology Specimens Confirm Persistent Colonization by : Case Report and Literature Review.

Case Rep Pathol 2022 13;2022:2151926. Epub 2022 May 13.

Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN, USA.

The published literature on cervicovaginal cytology includes fewer than ten reported cases of identified in Pap test samples. We report a unique case of an asymptomatic 27-year-old female with persistent gynecologic tract colonization by in which distinctive fungal microorganisms were identified in three samples collected over three consecutive years. Read More

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A Culturally Adapted Breast and Cervical Cancer Screening Intervention Among Muslim Women in New York City: Results from the MARHABA Trial.

J Cancer Educ 2022 May 19. Epub 2022 May 19.

Department of Population Health, NYU Langone Health, New York, NY, 10016, USA.

We examine the efficacy of MARHABA, a social marketing-informed, lay health worker (LHW) intervention with patient navigation (PN), to increase breast and cervical cancer screening among Muslim women in New York City. Muslim women were eligible if they were overdue for a mammogram and/or a Pap test. All participants attended a 1-h educational seminar with distribution of small media health education materials, after which randomization occurred. Read More

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Clinical validation of full HR-HPV genotyping HPV Selfy assay according to the international guidelines for HPV test requirements for cervical cancer screening on clinician-collected and self-collected samples.

J Transl Med 2022 05 17;20(1):231. Epub 2022 May 17.

Cervical Cancer Screening Coordination Unit, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.

Background: According to international guidelines, Human Papillomavirus (HPV) DNA tests represent a valid alternative to Pap Test for primary cervical cancer screening, provided that they guarantee balanced clinical sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more (CIN2+) lesions. The study aimed to assess whether HPV Selfy (Ulisse BioMed - Trieste, Italy), a full-genotyping HPV DNA test that detects and differentiates 14 high-risk HPV (HR-HPV) types, meets the criteria for primary cervical cancer screening described in the international guidelines, on clinician-collected as well as on self-collected samples.

Methods: For each participant woman, consecutively referring to Azienda Sanitaria Universitaria Giuliano Isontina (Trieste, Italy) and CRO-National Cancer Institute (Aviano, Italy) for the cervical cancer screening program, the following samples were tested: (a) a clinician-collected cervical specimen, analyzed with the reference test (Hybrid Capture®2 test, HC2) and HPV Selfy; and (b) a self-collected vaginal sample, analyzed with HPV Selfy. Read More

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Comparison of conventional and liquid-based Pap smear methods in the diagnosis of precancerous cervical lesions.

J Obstet Gynaecol 2022 May 17:1-5. Epub 2022 May 17.

Department of Obstetrics and Gynecology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Cervical cancer is one of the five most common cancers among women. The present study aimed to compare conventional and liquid-based Pap smear methods in 2018 in Kerman, Iran. This was a cross-sectional study. Read More

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Global online interest in cervical cancer care in the time of COVID-19: An infodemiology study.

Gynecol Oncol Rep 2022 Jun 10;41:100998. Epub 2022 May 10.

College of Medicine, University of the Philippines, Manila, Philippines.

Introduction: Internet search trends may gauge public awareness and interest in cancer and help identify key areas for improvement in public health interventions and awareness campaigns. During the COVID-19 pandemic, cervical cancer screening significantly decreased, and we hypothesized that this would be mirrored by a decreased online interest in cervical cancer care.

Methods: Using the Google Trends database, we analyzed 2018-2021 global search trends in the following topics: cervical cancer, human papillomavirus, HPV vaccine, Cervarix, Gardasil, Pap test, HPV test, and colposcopy. Read More

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Cervical Cancer Screening Uptake and Predictors Among Women in Jeddah, Saudi Arabia.

Cureus 2022 Apr 12;14(4):e24065. Epub 2022 Apr 12.

Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.

Introduction: Cervical cancer is one of the most common cancers among females, contributing to significant mortality and morbidity worldwide. These numbers have significantly decreased since the implementation of cervical cancer screening. Despite that, screening in many countries, including Saudi Arabia, remains suboptimal. Read More

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Video Head Impulse Test Changes Related to Obstructive Sleep Apnea: In Reply to the Work of Xin-Da Xu et al.

Front Neurol 2022 28;13:889187. Epub 2022 Apr 28.

Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

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Hybrid Model for Detection of Cervical Cancer Using Causal Analysis and Machine Learning Techniques.

Comput Math Methods Med 2022 4;2022:4688327. Epub 2022 May 4.

Division of Information and Computing Technology, College of Science and Engineering, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar.

Cervical cancer has become the third most common form of cancer in the in-universe, after the widespread breast cancer. Human papillomavirus risk of infection is linked to the majority of cancer cases. Preventive care, the most expensive way of fighting cancer, can protect about 37% of cancer cases. Read More

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The intersection of sexual orientation with race and ethnicity in cervical cancer screening.

Cancer 2022 May 16. Epub 2022 May 16.

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, Minneapolis, Minnesota.

Background: Cervical cancer screening is recommended for those with a cervix who are 21 to 65 years old, with specific timelines being dependent on individual risk. This study compared rates of ever undergoing Papanicolaou (Pap) testing at the intersection of self-reported sexual minority (SM) status and race/ethnicity.

Methods: Data from the National Health Interview Survey (2015 and 2018) were used to examine cervical cancer screening disparities. Read More

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Adequacy in Endocervical Curettage.

Am J Clin Pathol 2022 May 15. Epub 2022 May 15.

Department of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Objectives: Specimen adequacy is an important quality assurance component of a cervical Papanicolaou test. Although consensus exists on minimal acceptable cellularity for cervical Papanicolaou tests, no such criteria exist for endocervical curettage (ECC) specimens. We sought to identify minimum acceptable cellularity for accurate diagnosis of high-grade dysplasia (HGD) on ECC. Read More

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Acceptability of Human Papilloma Virus Self-Sampling for Cervical Cancer Screening in a Cohort of Patients from Romania (Stage 2).

J Clin Med 2022 Apr 29;11(9). Epub 2022 Apr 29.

Department of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

(1) Background: Low patient's adherence to conventional cervical cancer screening methods determined the need to take into consideration alternative approaches, and vaginal HPV self-sampling is one of them. We aimed to evaluate, using an online survey, the Romanian women's acceptability of vaginal HPV self-sampling. (2) Methods: A 13-questions online survey was distributed on three Facebook groups, and the results were summarized. Read More

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A deadly cold.

Victor O Kolade

Proc (Bayl Univ Med Cent) 2022 22;35(3):398. Epub 2022 Feb 22.

Department of Medicine, The Guthrie Clinic, Sayre, Pennsylvania.

This narrative describes how non-execution of screening at an urgent care visit may have delayed the diagnosis of cervical cancer in a young woman. Read More

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February 2022

Evaluation of a 2-1-1 Telephone Navigation Program to Increase Cancer Control Behaviors: Results From a Randomized Controlled Trial.

Am J Health Promot 2022 May 5:8901171211041276. Epub 2022 May 5.

Center for Health Promotion and Prevention Research, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.

Purpose: To evaluate the effectiveness of a telephone navigation intervention for increasing use of cancer control services among underserved 2-1-1 callers.

Design: Randomized controlled trial.

Setting: 2-1-1 call centers in Houston and Weslaco, Texas (located in the Rio Grande Valley near the Mexican border). Read More

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Screening technologies for cervical cancer: Overview.

Cytojournal 2022 29;19:23. Epub 2022 Mar 29.

Early Detection and Prevention Section/Screening Group, International Agency for Research on Cancer, Lyon, France.

Ever since the introduction of the Papanicolaou (PAP) smear test was published in 1941 in American Journal of Obstetrics and Gynecology, PAP test linked with definitive treatment has prevented millions of women from cervical cancer in the developed countries. Due to limited availability of resources, a lack of infrastructure and difficulty in getting highly trained professionals, widespread implementation of PAP test dependent cervical cancer screening program has not been established in low and middle income countries such as India. Therefore, after availability of non-cytological tests such as visual inspection on acetic acid (VIA) and human papillomavirus (HPV) DNA test, there is a paradigm shift in cervical cancer screening methods. Read More

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Pap Smear Collection and Preparation: Key Points.

Meherbano Kamal

Cytojournal 2022 29;19:24. Epub 2022 Mar 29.

Department of Pathology, Government Medical College, Nagpur, Maharashtra, India.

Cytology is the science of study of cells. It is derived from the Greek word "cytos" which means cells. The cells of the cervicovaginal epithelium are continuously evolving. Read More

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A community-based cervical cancer screening program in Alappuzha district of Kerala using camp approach.

J Family Med Prim Care 2022 Mar 10;11(3):1152-1157. Epub 2022 Mar 10.

Department of Community Medicine, Government TD Medical College, Alappuzha, Kerala, India.

Background: Cervical cancer is a major cause of preventable cancer related death in women, particularly in middle-income developing countries. Screening of cervical pre-cancer by cytology remains an effective strategy for prevention of mortality. However, there is paucity of community-based studies in Kerala. Read More

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Factors associated with mammography screening among Reunionese women : a cross-sectional study.

Rev Epidemiol Sante Publique 2022 Jun 28;70(3):117-122. Epub 2022 Apr 28.

Cancer Registry of the Reunion Island, Reunion University Hospital Center, Saint Denis, La Réunion, France; Methodological Support Unit, Reunion University Hospital Center, Saint Denis, La Réunion, France; Centre for Clinical Investigation (INSERM CIC1410), Saint Pierre, La Réunion, France.

Objective: To explore the factors associated with the uptake of mammography screening in Reunionese women aged 50-65 years.

Methods: This study included all women aged 50 to 65 years participating in a population-based cross-sectional study "FOSFORE". Participants were recruited between March and June 2017 using two sampling frames. Read More

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p16/Ki-67 Dual Staining Is a Reliable Biomarker for Risk Stratification for Patients With Borderline/Mild Cytology in Cervical Cancer Screening.

Anticancer Res 2022 May;42(5):2599-2606

Laboratory of Cell and Gene Therapy, Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.

Background/aim: To evaluate p16/Ki-67 dual-staining performance for detection of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) in the management of women with minor cervical abnormalities.

Patients And Methods: All 759 enrolled patients were tested for cytology, high-risk human papillomavirus (HR-HPV) and dual p16/Ki-67 staining.

Results: Positivity rates for HR-HPV and dual staining increased as dysplasia was worsened from non-CIN (37. Read More

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Efficacy of Oral Zinc Sulfate Supplementation on Clearance of Cervical Human Papillomavirus (HPV); A Randomized Controlled Clinical Trial.

Asian Pac J Cancer Prev 2022 Apr 1;23(4):1285-1290. Epub 2022 Apr 1.

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.

Aim: Human Papillomavirus is one of the most crucial infectious disease in gynecology disease. To assess the efficacy of supplemental zinc treatment in clearance of HPV infection.

Methods: Eighty zinc-sufficient women between 21-55 years, with positive HPV DNA testing, and abnormal cervical cytology in Pap test (ASCUS or LISL) were randomly divided to case (n=40) and control group (n=40). Read More

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What do South Asian immigrant women know about HPV, cervical cancer and its early detection: A cross-sectional Australian study.

J Migr Health 2022 8;5:100102. Epub 2022 Apr 8.

Centre for Health Services Research, Faculty of Medicine, The University of Queensland, Woolloongabba Queensland 4102, Australia.

Cervical cancer commonly caused by Human Papillomavirus (HPV) imposes a significant burden in Asia. This study examined the awareness and knowledge of HPV, cervical cancer, and its early detection methods among South Asian immigrant women in Australia to determine factors associated with knowledge deficits. A cross-sectional internet-based survey was completed by a convenience sample of women (n=148), with South-Asian background, residing in Queensland during May-October 2019. Read More

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The magnitude and predictors of cervical squamous intraepithelial lesions among women in Enugu, Nigeria: a cross-sectional study of women in a low-resource setting.

Pan Afr Med J 2022 16;41:130. Epub 2022 Feb 16.

Department of Community Medicine, University of Nigeria Teaching Hospital (UNTH), Enugu, Nigeria.

Introduction: the prevalence of cervical squamous intraepithelial lesion is not well appreciated in most low-income countries. The study aimed to determine the level of awareness, prevalence and the pattern of squamous intraepithelial lesions and predictors for abnormal Pap smear reports (development of pre-malignant lesions of the cervix) among women attending various clinics in a tertiary health facility in Enugu, Nigeria.

Methods: a cross-sectional study of 207 female patients attending various clinics of Enugu State University Teaching Hospital, Parklane, Enugu between June and August 2017 was undertaken. Read More

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Navigating Financial Barriers to Papanicolaou Tests and Mammograms for Young Adult Women Residing in Rural and Border Areas of Texas.

J Adolesc Young Adult Oncol 2022 Apr 26. Epub 2022 Apr 26.

Steve Hicks School of Social Work, The University of Texas at Austin, Austin, Texas, USA.

Costs of Papanicolaou (Pap) tests and mammograms are a primary barrier for women aged 18-39 seeking screening and diagnostic services. Race/ethnicity and rural/border resident status compound their risks for delayed diagnosis, possibly resulting in higher mortality. We analyzed cross-sectional data from young adult (YA) women (aged 18-39) from a cancer education and patient navigation (PN) program in rural and border Texas from 2012 to 2016. Read More

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Acceptability, simplicity, and relevance of the new human papillomavirus/DNA test among 35-year-old ever-married women in a district of Sri Lanka: focus group discussions.

BMC Womens Health 2022 Apr 25;22(1):131. Epub 2022 Apr 25.

Faculty of Medicine, University of Kelaniya, Gampaha, Sri Lanka.

Background: Two major drawbacks of the present cervical cancer screening programme in Sri Lanka are, the suboptimal sensitivity of the pap smear and the low coverage. The sensitivity of the HPV/DNA screening test is high. The objective of the study was to explore the acceptability relevance and simplicity of the new HPV/DNA screening implementation among ever-married women in a district of Sri Lanka. Read More

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COVID-19 Pandemic Effects on Cervical Cancer Diagnosis and Management: A Population-Based Study in Romania.

Diagnostics (Basel) 2022 Apr 6;12(4). Epub 2022 Apr 6.

Department of Obstetrics and Gynecology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.

The Pap test plays a significant role worldwide in the early diagnosis of and high curability rates for cervical cancer. However, the coronavirus disease 2019 (COVID-19) pandemic necessitated the use of multiple drastic measures to stop the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, limiting women's access to essential invasive and non-invasive investigations for cervical cancer diagnosis. Therefore, we aimed to determine the impact the COVID-19 pandemic had on cancer diagnosis and management in western Romania. Read More

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The Diagnosis of Cervical Dysplasia in a University Hospital Using Pap Smear and Colposcopy in the Western Region of Saudi Arabia: A Correlational Study.

Cureus 2022 Mar 17;14(3):e23242. Epub 2022 Mar 17.

Obstetrics and Gynaecology, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.

Objectives To assess the diagnostic performance of Pap smear screening with or without human papillomavirus (HPV) testing and colposcopy in detecting preinvasive lesions of the cervix among women with reference to histopathological findings. Materials and methods We performed a retrospective study in a tertiary care center of the clinical and pathological records of women with evocative symptomatology. The diagnostic performance of Pap smear screening and colposcopy was analyzed. Read More

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Perceptions and attitude of women of Luderitz, Namibia on Pap smear and cervical cancer prevention.

BMC Womens Health 2022 Apr 21;22(1):126. Epub 2022 Apr 21.

Department of Health Sciences, Faculty of Health and Applied Sciences, Namibia University of Science and Technology, Private Bag 13388, Windhoek, 9000, Namibia.

Background: Cervical cancer is one of the leading malignancies globally and has taken third place in Namibia amongst women aged 15-44 years. Infection with the Human Immunodeficiency Virus (HIV) has been proven to increase women's susceptibility to developing cervical carcinoma. Sadly, Namibia carries a twin burden of HIV and cervical cancer. Read More

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Prevalence of cervical abnormalities among rural women in KwaZulu-Natal, South Africa.

Pan Afr Med J 2022 8;41:110. Epub 2022 Feb 8.

Department of Public Health Medicine, School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Introduction: despite the availability of screening facilities in South Africa, cervical cancer prevalence and mortality is still high. Most women present to the health facilities at an advanced stage of disease. This study aimed to determine the prevalence of cervical abnormalities using the revised Bethesda System among rural women in KwaZulu-Natal, South Africa. Read More

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Social support and cervical cancer screening among sub-Saharan African immigrant (SAI) women.

Cancer Causes Control 2022 Jun 15;33(6):823-830. Epub 2022 Apr 15.

University of Kentucky, College of Nursing, Lexington, KY, 40536-0232, USA.

Background: Low rates of Papanicolaou (Pap) screening among sub-Saharan African immigrant (SAI) women in the US contribute to cancer diagnoses at late stages and high mortality rates. This study was conducted to examine if social support, positively associated with preventive health practices, was predictive of Pap screening in a sample of SAI women.

Methods: We conducted a cross-sectional study with SAI women who recently immigrated to the US. Read More

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Pepsin-like aspartic proteases (PAPs) as model systems for combining biomolecular simulation with biophysical experiments.

RSC Adv 2021 Mar 17;11(18):11026-11047. Epub 2021 Mar 17.

Division of Biophysical Chemistry, Center for Molecular Protein Science, Department of Chemistry, Lund University P. O. Box 124 SE-22100 Lund Sweden +46-769608418.

Pepsin-like aspartic proteases (PAPs) are a class of aspartic proteases which shares tremendous structural similarity with human pepsin. One of the key structural features of PAPs is the presence of a β-hairpin motif otherwise known as flap. The biological function of the PAPs is highly dependent on the conformational dynamics of the flap region. Read More

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Lung Volume Reduction Surgery Reduces Pulmonary Arterial Hypertension Associated with Severe Lung Emphysema and Hypercapnia.

ASAIO J 2022 Apr 13. Epub 2022 Apr 13.

From the Department of Thoracic Surgery and Lung Support, Ibbenbueren General Hospital, Ibbenbueren, Germany.

Lung volume reduction surgery (LVRS) represents a standard surgical approach for patients with severe pulmonary emphysema. One of the relevant risk factors for LVRS is the presence of pulmonary arterial hypertension (PAH). The aim of this study is to assess the postoperative changes in pulmonary arterial pressure (PAP) after LVRS for patients with severe pulmonary emphysema compared with preoperative measures. Read More

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