23,409 results match your criteria palliation surgical

[Comparison of catheter-associated quality of life in external urinary diversion: nephrostomy vs. suprapubic catheter].

Urologe A 2022 Jan 13. Epub 2022 Jan 13.

Lehrstuhl für Geriatrie, Universität Witten/Herdecke, Witten, Deutschland.

Introduction: A percutaneous nephrostomy (PCN) affects the integrity of the patient due to the requirement of an external drainage bag and regular changes. The catheter-associated quality of life (QOL) was evaluated using a validated assessment and compared to similar patients with suprapubic bladder drainage.

Methods: A validated assessment analyzing catheter-related QOL for 5 domains and 25 individual items (first published by Mary Wilde) was completed during a catheter change appointment by patients who had their unilateral or bilateral PCN for a minimum of 3 months in life-long indication. Read More

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January 2022

Transcatheter aortic valve implantation for severe aortic stenosis in a patient with mucopolysaccharidosis type II (Hunter syndrome) accompanied by severe airway obstruction.

J Cardiol Cases 2022 Jan 3;25(1):49-51. Epub 2021 Jul 3.

Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku 260-8677, Chiba, Japan.

Mucopolysaccharidosis type II, known as Hunter syndrome, is a rare inherited metabolic disorder with glycosaminoglycan accumulation leading to progressive multisystem involvement, such as heart, respiratory, and central nervous systems. In particular, concurrence of major heart and respiratory problems in this syndrome often causes difficulty in performing curative and invasive treatments. Transcatheter aortic valve implantation (TAVI) has been an established therapy for severe aortic stenosis (AS). Read More

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January 2022

Pembrolizumab Achieves a Complete Response in an NF-1 Mutated, PD-L1 Positive Malignant Peripheral Nerve Sheath Tumor: A Case Report and Review of the Benchmarks.

J Immunother 2022 Jan 12. Epub 2022 Jan 12.

University of Arizona College of Medicine Departments of Internal Medicine Medical Imaging Pathology Oncology, University of Arizona, Tucson, AZ Mayo Clinic Cancer Center, Mayo Clinic Florida, Jacksonville, FL Mays Cancer Center/MD Anderson, University of Texas Health San Antonio, San Antonio, TX.

Malignant peripheral nerve sheath tumors (MPNSTs) represent a rare subtype of neural crest cell-derived soft tissue sarcomas (STS). Standard of care therapy comprises surgical resection followed by adjuvant radiation, and most clinical studies have demonstrated finite survival benefit of radiation and chemotherapy. In metastatic disease, palliative chemotherapy provides very limited efficacy. Read More

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January 2022

Communication in surgery: the therapy of hope.

Laura A Lambert

Ann Palliat Med 2022 Jan 10. Epub 2022 Jan 10.

Department of Surgery, University of Utah, Huntsman Cancer Institute, Salt Lake City, UT, USA.

Surgeons are frequently consulted for assistance in the palliative management of patients, and surgery is an essential tool in the armamentarium of comprehensive palliative care. Palliative surgical consults are some of the most challenging surgical consults, not only for technical reasons, but also because of the (usually) higher odds of morbidity or mortality, often in the setting of a limited life expectancy. Surgery is also often seen as the last possibility of hope, which can place a great emotional burden on the surgeon. Read More

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January 2022

Post-tracheostomy complications: respiratory failure caused by authologic foreign body-case report.

Ann Palliat Med 2022 Jan 4. Epub 2022 Jan 4.

Department of Pulmonology and Respiratory Intensive Care Unit, S. Donato Hospital, Arezzo, Italy.

Tracheostomy is performed frequently as a palliative treatment in patients with end-stage respiratory failure (RF). However, in patients requiring prolonged mechanical ventilation it may be difficult to recognize and can often lead to life-threatening RF. We present two cases of acute-on-chronic respiratory failure (ACRF) occurring in patients who had undergone tracheostomy [one with percutaneous dilatational tracheostomy (PDT) and the second with surgical tracheostomy (ST)]. Read More

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January 2022

More often than not, we're in sync: patient and caregiver well-being over time in stem cell transplantation.

Health Qual Life Outcomes 2022 Jan 10;20(1). Epub 2022 Jan 10.

Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, USA.

Background: Hematopoietic stem cell transplantation (HSCT) is an aggressive medical procedure which significantly impacts the shared emotional well-being of patients and family caregivers (FC). Prior work has highlighted the significant overlap in well-being among patients and FCs; however, how this interdependence may change over the course of HSCT has received less attention.

Methods: We conducted secondary analyses of a supportive intervention delivered to 154 FCs of HSCT patients and examined relationships at baseline, 6 weeks, 3 and 6 months post-HSCT. Read More

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January 2022

Approval rates for corneal donation and the origin of donor tissue for transplantation at a university-based tertiary referral center with corneal subspecialization hosting a LIONS Eye Bank.

BMC Ophthalmol 2022 Jan 10;22(1):17. Epub 2022 Jan 10.

Department of Ophthalmology, Saarland University Medical Center (UKS), Kirrberger Straße 100, Building 22, 66421, Homburg/Saar, Germany.

Background: With the increasing demand for corneas, eye banks must optimize the tissue donation, collection, and selection process. This retrospective monocentric study analyzed the approval rates for corneal donation and the origin of and reasons for discarding donor corneas from 2010 to 2019.

Methods: Data included the number of deceased, approval or rejection by the family for corneal donation and contraindications. Read More

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January 2022

Idiopathic Pulmonary Fibrosis Complicated by Adenocarcinoma and Organizing Pneumonia.

Cureus 2022 Jan 4;14(1):e20916. Epub 2022 Jan 4.

Respiratory Medicine, Hamanomachi Hospital, Fukuoka, JPN.

We describe a case of a 77-year-old male with idiopathic pulmonary fibrosis (IPF) complicated by lung adenocarcinoma and organizing pneumonia (OP). On initial examination, physical examination revealed fine crackles in both sides of his chest. There were no physical findings suggestive of collagen disease. Read More

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January 2022

When there is only one patient: Induction of labour for termination of pregnancy.

Best Pract Res Clin Obstet Gynaecol 2021 Nov 17. Epub 2021 Nov 17.

Department of Obstetrics and Gynaecology, McMaster University, Hamilton, L8N 3Z5, Canada.

Induction of labour when no live birth is anticipated presents a number of unique considerations for members of the healthcare team. The main indication for Induction of Labour for Termination of Pregnancy (iTOP) is intrauterine fetal death (IUFD) beyond a gestational age where surgical management is available, but may also be indicated in the setting of induction abortion (with or without feticide), and termination of pregnancy (with or without infant palliation) for pregnancies where a lethal fetal anomaly is diagnosed. In tertiary care centres, iTOP may represent a significant proportion of labouring patients. Read More

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November 2021

Impact of 3D Printing on Short-Term Outcomes of Biventricular Conversion From Single Ventricular Palliation for the Complex Congenital Heart Defects.

Front Cardiovasc Med 2021 21;8:801444. Epub 2021 Dec 21.

Department of Cardiothoracic Surgery, Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Although Fontan palliation seems to be inevitable for many patients with complex congenital heart defects (CHDs), candidates with appropriate conditions could be selected for biventricular conversion. We aimed to summarize our single-center experience in patient selection, surgical strategies, and early outcomes in biventricular conversion for the complex CHD. From April 2017 to June 2021, we reviewed 23 cases with complex CHD who underwent biventricular conversion. Read More

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December 2021

Real-Life Clinical Data of Lenvatinib versus Sorafenib for Unresectable Hepatocellular Carcinoma in Italy.

Cancer Manag Res 2021 24;13:9379-9389. Epub 2021 Dec 24.

Hepatobiliary Surgery Division, Liver Center, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, 20132, Italy.

Background: Lenvatinib has been approved in Italy since October 2019 as a first-line therapy for advanced hepatocellular carcinoma (HCC) and to date data on effectiveness and safety of lenvatinib are not available in our region. To fill this gap, we performed a multicentric analysis of the real-world treatment outcomes with the propensity score matching in a cohort of Italian patients with unresectable HCC who were treated with either sorafenib or lenvatinib.

Aims And Methods: To evaluate the effectiveness of sorafenib and lenvatinib as primary treatment of advanced HCC in clinical practice we performed a multicentric analysis of the treatment outcomes of 288 such patients recruited in 11 centers in Italy. Read More

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December 2021

Pediatric heart-lung transplantation: Technique and special considerations.

J Heart Lung Transplant 2021 Dec 16. Epub 2021 Dec 16.

Section of Pediatric Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis/St. Louis Children's Hospital, St. Louis, Missouri. Electronic address:

Heart-lung transplantation has historically been used as a definitive treatment for children with end-stage cardiopulmonary failure, although the number performed has steadily decreased over time. In this review, we discuss current indications, preoperative risk factors, outcomes, and heart-lung transplantation in unique patient subsets, including infants, children with single-ventricle physiology, tetralogy of Fallot/major aortopulmonary collateral arteries, and prior Potts shunt palliation. We also describe the different surgical techniques utilized in pediatric heart-lung transplantation. Read More

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December 2021

Improving Code Status Documentation Rates Using Communication Skills Training in Vascular Surgery: A Quality Improvement Initiative.

J Palliat Med 2022 Jan 6. Epub 2022 Jan 6.

Section of Palliative Care and Medical Ethics, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Code status discussions are poorly understood by patients and variably performed by admitting providers, yet they are used as a quality metric. Surgical specialties, such as Vascular Surgery, admit patients with urgent and life-threatening illness. Surgical trainees are less likely to receive communication skills interventions when compared with nonsurgical specialties. Read More

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January 2022

Clinical application of advances and innovation in radiation treatment of hepatocellular carcinoma.

J Clin Transl Res 2021 Dec 6;7(6):811-833. Epub 2021 Nov 6.

Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, 308433, Singapore.

Background: Hepatocellular carcinoma (HCC) management has evolved over the past two decades, with the development of newer treatment modalities. While various options are available, unmet needs are reflected through the mixed treatment outcome for intermediate-stage HCC. As HCC is radiosensitive, radiation therapies have a significant role in management. Read More

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December 2021

UK Medical Cannabis Registry palliative care patients cohort: initial experience and outcomes.

J Cannabis Res 2022 Jan 4;4(1). Epub 2022 Jan 4.

Department of Surgery and Cancer, St Mary's Hospital, Imperial College Medical Cannabis Research Group, Imperial College London, Academic Surgical Unit, 10th Floor QEQM, South Wharf Road, London, W2 1NY, UK.

Introduction: Palliative care aims to improve quality of life through optimal symptom control and pain management. Cannabis-based medicinal products (CBMPs) have a proven role in the treatment of chemotherapy-induced nausea and vomiting. However, there is a paucity of high-quality evidence with regards to the optimal therapeutic regimen, safety, and effectiveness of CBMPs in palliative care, as existing clinical trials are limited by methodological heterogeneity. Read More

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January 2022

Clinical features, demography, and predictors of outcomes of SARS-CoV-2 infection at a tertiary care hospital in India: A cohort study.

Lung India 2022 Jan-Feb;39(1):16-26

Department of Palliative Medicine, All India Institute of Medical Sciences, New Delhi, India.

Background: The "second wave" of the COVID-19 pandemic hit India from early April 2021 to June 2021. We describe the clinical features, treatment trends, and baseline laboratory parameters of a cohort of patients with SARS-CoV-2 infection and their association with the outcome.

Methods: This was a retrospective cohort study. Read More

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January 2022

Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy.

Int J Obes (Lond) 2022 Jan 1. Epub 2022 Jan 1.

Department of Surgery, Voss Hospital, Haukeland University Hospital, Voss, Norway.

Background/objectives: There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and comorbidities. We aimed to determine 7-year trajectories of body mass index (BMI), QOL, obesity-related comorbidities, biomarkers of glucose and lipid metabolism, and early major complications after SG and RYGB.

Subjects/methods: Patients scheduled for bariatric surgery at two Norwegian hospitals, preferentially performing either SG or RYGB, were included consecutively from September 2011 to February 2015. Read More

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January 2022

Retrospective analysis of post-tracheostomy complications.

Am J Otolaryngol 2021 Dec 24;43(2):103350. Epub 2021 Dec 24.

Medical College of Wisconsin, 8701 W Watertown Plank Rd, Wauwatosa, WI 53226, United States of America.

Objective: To elucidate patient, disease, and surgical factors that are significantly associated with 90-day tracheostomy complications, readmissions, and mortality.

Study Design: Retrospective case series with chart review.

Setting: A single academic tertiary care center between 2011 and 2018. Read More

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December 2021

Risk factors for Coronavirus disease-associated mucormycosis.

J Infect 2021 Dec 30. Epub 2021 Dec 30.

Department of Medicine, AIIMS, Delhi, India.

Background: The epidemiology of the Coronavirus-disease associated mucormycosis (CAM) syndemic is poorly elucidated. We aimed to identify risk factors that may explain the burden of cases and help develop preventive strategies.

Methods: We performed a case-control study comparing cases diagnosed with CAM and taking controls as recovered COVID 19 patients who did not develop mucormycosis. Read More

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December 2021

Squamous cell carcinoma complicating chronic osteomyelitis: A systematic review and case series.

Surgeon 2021 Dec 28. Epub 2021 Dec 28.

Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Windmill Road, Oxford, OX3 7HE, UK. Electronic address:

Introduction: Squamous cell carcinoma (SCC) is a rare but serious complication of chronic osteomyelitis. This study aimed to determine an optimum approach to diagnosis and management.

Methods: A systematic review was performed using Medline, Embase, CINAHL and Web of Science, from 1999-present. Read More

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December 2021

Is there a role for endovascular stent implantation in the management of postoperative right ventricular outflow tract obstruction in the era of transcatheter valve implantation?

Catheter Cardiovasc Interv 2021 Dec 30. Epub 2021 Dec 30.

The Department of Pediatrics, Division of Cardiology, The Labatt Family Heart Center, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada.

Background: The optimal management pathway for the dysfunctional right ventricular outflow tract (RVOT) is uncertain. We evaluated the long-term outcomes and clinical impact of stent implantation for obstructed RVOTs in an era of rapidly progressing transcatheter pulmonary valve technology.

Methods: Retrospective review of 151 children with a biventricular repair who underwent stenting of obstructed RVOT between 1991 and 2017. Read More

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December 2021

Predictive factors of early outcome after palliative surgery for colorectal carcinoma.

Innov Surg Sci 2020 Sep 2;5(3-4):91-103. Epub 2020 Nov 2.

Chirurgische Klinik, Universitätsklinikum Erlangen, Erlangen, Germany.

Objectives: A significant number of patients with colorectal cancer are presented with various conditions requiring surgery in an oncologically palliative setting. We performed this study to identify risk factors for early outcome after surgery to facilitate the decision-making process for therapy in a palliative disease.

Methods: We performed a retrospective chart review of 142 patients who underwent palliative surgery due to locally advanced, complicated, or advanced metastatic colorectal carcinoma between January 2010 and April 2018 at the "Elbland" Medical Center Riesa. Read More

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September 2020

What Factors Are Associated with Local Metastatic Lesion Progression After Intramedullary Nail Stabilization?

Clin Orthop Relat Res 2021 Dec 28. Epub 2021 Dec 28.

Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, MD, USA.

Background: Pathologic fracture of the long bones is a common complication of bone metastases. Intramedullary nail stabilization can be used prophylactically (for impending fractures) or therapeutically (for completed fractures) to preserve mobility and quality of life. However, local disease progression may occur after such treatment, and there is concern that surgical instrumentation and the intramedullary nail itself may seed tumor cells along the intramedullary tract, ultimately leading to loss of structural integrity of the construct. Read More

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December 2021

Anesthesia Techniques and Long-Term Oncological Outcomes.

Front Oncol 2021 8;11:788918. Epub 2021 Dec 8.

Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Despite advances in cancer treatments, surgery remains one of the most important therapies for solid tumors. Unfortunately, surgery promotes angiogenesis, shedding of cancer cells into the circulation and suppresses anti-tumor immunity. Together this increases the risk of tumor metastasis, accelerated growth of pre-existing micro-metastasis and cancer recurrence. Read More

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December 2021

Assigning green hospitals during the COVID-19 pandemic assure continuous and safe resumption of surgical services.

Ann Med Surg (Lond) 2022 Jan 21;73:103207. Epub 2021 Dec 21.

Department of Family Medicine, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia.

Background: Coronavirus 19 pandemic impacted the health system with more pressure on the critical areas, leading to direct manpower working in the Operating Room to help treat this new problem by postponing elective surgical cases and affecting some urgent ones. However, elective surgical services start to recover by establishing one or more hospitals that deal with COVID-19 free patients (green hospital) in each area with a dedicated one to treat COVID19 cases. Our research shows if this model's application assures safe and continued recovery of surgical services to reach the level before the pandemic. Read More

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January 2022

Metabolic disorders and gastroenteropancreatic-neuroendocrine tumors (GEP-NETs): How do they influence each other? An Italian Association of Medical Oncology (AIOM)/ Italian Association of Medical Diabetologists (AMD)/ Italian Society of Endocrinology (SIE)/ Italian Society of Pharmacology (SIF) multidisciplinary consensus position paper.

Crit Rev Oncol Hematol 2022 Jan 22;169:103572. Epub 2021 Dec 22.

Department of Emergency and Organ Transplantation, Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari Aldo Moro, Bari, Italy. Electronic address:

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of malignancies derived from neuroendocrine cells that can occur anywhere along the gastrointestinal tract. GEP-NETs incidence has been steadily increasing over the past decades, in parallel with the increasing incidence of the metabolic syndrome (MetS). It is not yet fully known whether the MetS components (such as obesity, dyslipidemia and type 2 diabetes) could be involved in the etiology of GEP-NETs or could influence their outcomes. Read More

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January 2022

Non-home discharge after cardiac surgery in Australia and New Zealand: a cross-sectional study.

BMJ Open 2021 Dec 23;11(12):e049187. Epub 2021 Dec 23.

School of Medicine, The University of Queensland School of Medicine, Herston, Queensland, Australia.

Objective: To determine the proportion of patients surviving their cardiac surgery who experienced non-home discharge (NHD) over a 16-year period in Australia and New Zealand (ANZ).

Design: Retrospective, multicentre, cross-sectional study over the time period 01 January 2004 to 31 December 2019.

Setting: Adult patients who underwent cardiac surgery from the Australia New Zealand Intensive Care Society Adult Patient Database (APD). Read More

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December 2021

One-year mortality after hospital admission as an indicator of palliative care need: A retrospective cohort study.

S Afr Med J 2021 Nov 5;111(11):1070-1073. Epub 2021 Nov 5.

Division of General Medicine, Department of Medicine, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town, South Africa.

Background: Globally there is increasing awareness of the need for end-of-life care and palliative care in hospitalised patients who are in their final year of life. Limited data are available on palliative care requirements in low- and middle-income countries, hindering the design and implementation of effective policies and health services for these patients.

Objectives: To determine the proportion of patients who die within 1 year of their date of admission to public hospitals in South Africa (SA), as a proxy for palliative care need in SA. Read More

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November 2021

Volumetric Modulated Arc Therapy Capabilities for Treating Lower-Extremity Skin Affected by Several Merkel Cell Carcinoma Nodules: When Technological Advances Effectively Achieve the Palliative Therapeutic Goal while Minimising the Risk of Potential Toxicities.

Medicina (Kaunas) 2021 Dec 18;57(12). Epub 2021 Dec 18.

Humanitas C.C.O., I-95125 Catania, CT, Italy.

The peculiar and rare clinical condition below clearly requires a customized care approach in the context of personalized medicine. An 80-year-old female patient who was subjected in 2018 to surgical removal of a cutaneous Merkel cell carcinoma (MCC) nodule located on the posterior surface of the left thigh and to three subsequent palliative radiotherapy treatments developed a fourth relapse in October 2020, with fifteen nodular metastases located in the left thigh and leg. Since the overall macroscopic disease was still exclusively regionally located and microscopic spread was likely extended also to clinically negative skin of the thigh and leg, we performed an irradiation of the whole left lower extremity. Read More

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December 2021

Brain Metastases from Adult Sarcomas: A Retrospective Cohort Study from the Hellenic Group of Sarcomas and Rare Cancers (HGSRC).

J Clin Med 2021 Dec 20;10(24). Epub 2021 Dec 20.

Department of Medical Oncology, Bioclinic Hospital, 54622 Thessaloniki, Greece.

Brain metastases are rare events in patients with sarcoma and the available information is relatively limited. We retrospectively reviewed medical records of patients with sarcoma who developed brain metastases between April 2010 and April 2020 in six centers. Thirty-four adult patients were included with a median age at brain metastases diagnosis of 55. Read More

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December 2021