40,409 results match your criteria pain intensity


Outcome of carpal tunnel release surgery in patients with and without Linburg-Comstock anomaly.

Hand Surg Rehabil 2021 Jul 27. Epub 2021 Jul 27.

Hand Surgery Unit, Department of Orthopedic Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Borges Lagoa 786, São Paulo 04038-032, Brazil.

Anatomical variations may entail increased volume within the carpal tunnel and consequently the development of carpal tunnel syndrome (CTS) symptoms. The clinical importance of anomalous connection between the flexor pollicis longus (FPL) and flexor digitorum profundus (FDP) tendons was described by Linburg and Comstock. The objective of the present study was to compare postoperative outcomes of carpal tunnel release surgery in patients with and without Linburg-Comstock anomaly (LCA). Read More

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Pain Variability Predicts Subjective Function in Individuals with Patellofemoral Pain: A Short Report.

J Athl Train 2021 Jul 30. Epub 2021 Jul 30.

School of Exercise and Rehabilitation Sciences, University of Toledo, Toledo, OH. Email: Twitter:

Individuals with patellofemoral pain (PFP) experience pain during various functional activities. Long-term pain is a common consequence of PFP, yet little is known about daily pain variability. Twenty-five individuals with PFP completed the Anterior Knee Pain Scale (AKPS) and recorded daily pain over 10-days. Read More

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Methodology and applicability of the human contact burn injury model: A systematic review.

PLoS One 2021 30;16(7):e0254790. Epub 2021 Jul 30.

Department of Anesthesia, Multidisciplinary Pain Center, Pain and Respiratory Support, Neuroscience Center, Copenhagen University Hospital, Copenhagen, Denmark.

The contact burn injury model is an experimental contact thermode-based physiological pain model primarily applied in research of drug efficacy in humans. The employment of the contact burn injury model across studies has been inconsistent regarding essential methodological variables, challenging the validity of the model. This systematic review analyzes methodologies, outcomes, and research applications of the contact burn injury model. Read More

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Psychophysical predictors of experimental muscle pain intensity following fatiguing calf exercise.

PLoS One 2021 30;16(7):e0253945. Epub 2021 Jul 30.

Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.

Musculoskeletal pain affects approximately 20% of the population worldwide and represents one of the leading causes of global disability. As yet, precise mechanisms underlying the development of musculoskeletal pain and transition to chronicity remain unclear, though individual factors such as sleep quality, physical activity, affective state, pain catastrophizing and psychophysical pain sensitivity have all been suggested to be involved. This study aimed to investigate whether factors at baseline could predict musculoskeletal pain intensity to an experimental delayed onset of muscle soreness (DOMS) pain model. Read More

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Pain-coping types among older community-dwelling care receivers with chronic pain.

Aging Ment Health 2021 Jul 30:1-9. Epub 2021 Jul 30.

Institute of Medical Sociology and Rehabilitation Science, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Objectives: There is a lack of knowledge on coping with pain and sub-group specific pain-coping profiles among older home care receivers with chronic pain. To describe pain-coping strategies, identify subgroups based on cognitive and behavioral pain-coping strategies and pain-related psychological impairment and to compare these groups with regard to socio-demographic, medical, pharmacological and psychological characteristics.

Method: Data of 212 care receivers were examined using the German pain-coping questionnaire (FESV) to determine how they cope with pain. Read More

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Symptom severity is associated with signs of central sensitization in patients with asthma.

Clin Respir J 2021 Jul 30. Epub 2021 Jul 30.

Department of Physical Therapy, Faculty of Health Sciences. University of Granada, Granada, Spain.

Introduction: Asthma is characterized by recurrent episodes of wheezing, dyspnea, chest tightness and cough. In addition to respiratory symptoms, previous studies have reported the presence of pain.

Objective: To analyse the nociceptive processing of young adults with well-controlled asthma. Read More

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Intravoxel incoherent motion imaging predicts exercise-based rehabilitation response in individuals with low back pain.

NMR Biomed 2021 Jul 29:e4595. Epub 2021 Jul 29.

Department of Orthopaedic Surgery, University of California San Diego, La Jolla, California, USA.

Exercises to strengthen and stabilize the trunk musculature are a common conservative treatment strategy for low back pain (LBP), despite the possible presence of impairments in muscle activation in this population. Intravoxel incoherent motion (IVIM) MRI permits evaluation of activation-induced blood flow through diffusion-weighted images that are sensitized to microvascular blood flow. In the current study we aimed to evaluate IVIM signal changes after exercise in patients with LBP compared with pain-free healthy controls and determine if these changes were related to reductions in disability with a 12-week rehabilitation program. Read More

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Effects of Language Context and Cultural Identity on the Pain Experience of Spanish-English Bilinguals.

Affect Sci 2020 Jun 30;2(2):112-127. Epub 2020 Nov 30.

University of Miami, Department of Psychology, Miami, FL, USA.

While language and culture influence cognition, their role in shaping pain remains understudied. We tested whether language and cultural identification influence pain report among Spanish-English bilinguals. Eighty bilingual Hispanics/Latinos (40 female) experienced painful thermal stimulations, providing pain intensity and unpleasantness ratings, on separate English and Spanish testing days. Read More

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Comparison of cervical muscle isometric force between migraine subgroups or migraine-associated neck pain: a controlled study.

Sci Rep 2021 Jul 29;11(1):15434. Epub 2021 Jul 29.

Department of Health Sciences, Ribeirão Preto Medical School of the University of São Paulo, Ribeirão Preto, 14049-900, Brazil.

This study aimed to verify if migraine frequency or migraine-associated neck pain were associated with a reduction of normalized force and altered electromyographic activity during maximal cervical muscle isometric contractions. Additionally, it aimed to assess the correlation of normalized isometric force with years with migraine, headache frequency, headache intensity, migraine-related disability, and severity of cutaneous allodynia. The sample comprises 71 women with migraine (40/31 episodic/chronic, 42/18 with/without neck pain) and 32 women without headache. Read More

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Yoga for treating low back pain: a systematic review and meta-analysis.

Pain 2021 Jul 28. Epub 2021 Jul 28.

Department of Internal and Integrative Medicine, Evang. Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany. National Centre for Naturopathic Medicine, Southern Cross University, Lismore, Australia. Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney, Sydney, Australia.

Abstract: Yoga is frequently used for back pain relief. However, evidence was judged to be of only low- or moderate. To assess the efficacy and safety of yoga in patients with low back pain a meta-analysis was performed. Read More

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The efficacy and safety of MR-HIFU and US-HIFU in treating uterine fibroids with the volume <300 cm: a meta-analysis.

Int J Hyperthermia 2021 ;38(1):1126-1132

Department of Gynecology, Jiangsu Province Hospital, Nanjing, China.

Background: High-intensity focused ultrasound (HIFU) is a promising and non-invasive therapy for symptomatic uterine fibroids. Currently, the main image-guided methods for HIFU include magnetic resonance-guided (MR-HIFU) and ultrasound-guided (US-HIFU). However, there are few comparative studies on the therapeutic efficacy and safety of MR-HIFU and US-HIFU in treating symptomatic uterine fibroids with a volume <300 cm. Read More

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January 2021

Treatment of medication overuse headache: Effect and predictors after 1 year-A randomized controlled trial.

Headache 2021 Jul 29. Epub 2021 Jul 29.

Danish Headache Center, Rigshospitalet-Glostrup, Valdemar Hansens Vej 5, Glostrup, 2600, Denmark.

Background: Combined withdrawal and early preventive medication was the most effective treatment for medication overuse headache (MOH) within the first 6 months in a previous study, but results from a longer follow-up period are lacking.

Objective: (1) To measure the efficacy at 1 year of three different treatment approaches to MOH; (2) to compare withdrawal and early preventives (W+P), preventives with potential withdrawal therapy after 6 months (P+pW), and withdrawal with delayed potential preventives (W+pP); and (3) to identify predictors of chronic headache after 1 year.

Methods: Patients with MOH and migraine and/or tension-type headache were randomly assigned to one of the three outpatient treatments. Read More

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Hemicrania continua in a family: A report of two cases.

Headache 2021 Jul 29. Epub 2021 Jul 29.

Division of Headache, Department of Neurology, NYU Langone Health, New York, NY, USA.

Objective: To report two cases of hemicrania continua (HC) in a mother and daughter.

Background: HC is a rare primary headache disorder belonging to the family of trigeminal autonomic cephalalgias (TACs). Unlike migraine, familial cases of TACs are rare, and we know relatively little of their inheritance pattern and genetic mechanisms. Read More

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The effect of erector spinae plane block on postoperative analgesia and respiratory function in patients undergoing laparoscopic cholecystectomy: A double-blind randomized controlled trial.

J Clin Anesth 2021 Jul 26;74:110403. Epub 2021 Jul 26.

University of Health Science, Konya City Hospital, Department of Anesthesiology and Reanimation, Konya, Turkey.

Study Objective: Laparoscopic cholecystectomy (LC) causes moderate-to-severe postoperative pain. Postoperative pain is one of the leading contributors to respiratory dysfunction following surgery. This study investigated the effect of erector spinae plane (ESP) block on postoperative analgesia and respiratory function in patients undergoing LC. Read More

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Ultrasound-guided popliteal sciatic nerve block in a pediatric patient with complex regional pain syndrome: a case report.

Braz J Anesthesiol 2021 Jul 26. Epub 2021 Jul 26.

Universidade Federal do Maranhão (UFMA), São Luís, MA, Brazil. Electronic address:

In the pediatric population, complex regional pain syndrome (CRPS) is a challenging condition that leads to chronic psychosocial dysfunction. This case is of a 12-year-old male patient, 50 kg, who, after twisting his right ankle, started to present intense pain. Without adequate diagnosis and treatment, his family sought a pain specialist. Read More

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Predicting Clinical Improvement for Patients with Low Back Pain: Keeping it Simple for Patients Seeking Physical Therapy Care.

Phys Ther 2021 Jul 28. Epub 2021 Jul 28.

Rehabilitation Services, Intermountain Healthcare, Salt Lake City, Utah.

Objective: Develop and validate an original prediction formula that estimated the probability of success for patients with LBP to achieve a minimal clinical important difference (MCID) on the Modified Low Back Disability Questionnaire (MDQ).

Methods: Patients were 10 to 90 years old in this retrospective cohort study. Data was extracted from Intermountain Healthcare's registry, Rehabilitation Outcomes Management System (ROMS): 62,858 patients admitted to physical therapy from 2002 to 2013 formed the training dataset and 15,128, patients admitted 2015 to 2016 formed the verification dataset. Read More

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Transforaminal Epidural Steroid Injection for Zoster-Related Pain: The Golden Period for the Best Outcome.

Pain Physician 2021 Aug;24(5):E669-E676

Seoul National University, Bundang Hospital, Seongnam, Korea.

Background: Zoster-related pain (ZRP) has many negative effects on a patient's quality of life. The transforaminal steroid injection (TFESI), which reduces neural inflammation and pain, has been advocated by pain physicians. Many reports demonstrated that early administration of TFESI showed better efficacy; however, the golden period during which TFESI is most effective remains unclear. Read More

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Treatment of Thoracolumbar Type A3 Fractures Using a Percutaneous Intravertebral Expandable Titanium Implant: Long-term Follow-up Results of a Pilot Single Center Study.

Pain Physician 2021 Aug;24(5):E631-E638

Unidad de Columna, Servicio Cirugía Ortopédica, Hospital Clínico Universitario de Valladolid, Spain.

Background:   There are controversies about the optimal management of AO subtype A3 burst fractures. The most common surgical treatment consists of posterior fixation with pedicle screw and rod augmentation. Nevertheless, a loss of correction in height restoration and kyphotic reduction has been observed. Read More

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Retrospective Study of the Analgesic Effect of Sacroiliac Joint Radiofrequency Denervation.

Pain Physician 2021 Aug;24(5):E625-E629

Department of Anesthesiology, Universidade Federal de São Paulo, Sâo Paulo, Brazil.

Background: Interventional radiofrequency (RF) ablation techniques are indicated when an adequate effect is not obtained with conservative measures.

Objectives: The primary objective of this study was to evaluate pain relief after RF denervation of the sacroiliac joint. The secondary objective was to evaluate pain intensity and relief duration. Read More

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The Effect of Social Isolation During the COVID-19 Pandemic on Patients with Chronic Low Back Pain Who Underwent a Spine Intervention.

Pain Physician 2021 Aug;24(5):319-325

University of Health Sciences, Gulhane School of Medicine, Department of PM&R, Gaziler Physical Therapy and Rehabilitation Training and Research Hospital, Ankara, Turkey.

Background: The COVID-19 infection poses a serious threat to global health for millions of people. In addition to therapeutic treatment methods, preventive measures are also important in controlling the pandemic. As a result, billions of people are quarantined in their homes to prevent the spread of coronavirus. Read More

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Acupressure and Acupuncture Use in the Peripartum Period.

Clin Obstet Gynecol 2021 Sep;64(3):558-571

School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia.

Acupuncture is the procedure of inserting fine needles into specific points on the body for therapeutic purposes. Acupuncture and its derivatives (acupressure, moxibustion, electroacupuncture, and transcutaneous electric nerve stimulation on acupoints) are a popular treatment choice in the peripartum period (32 wk' gestation to 14 d postdelivery). There is substantial research evidence supporting acupuncture and its derivatives in the peripartum period. Read More

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September 2021

Circulating long non-coding RNA signature in knee osteoarthritis patients with postoperative pain one-year after total knee replacement.

Scand J Pain 2021 Jul 29. Epub 2021 Jul 29.

Department of Health Science and Technology, Faculty of Medicine, Center for Sensory-Motor Interaction (SMI), Aalborg University, Aalborg, Denmark.

Objectives: The incidence of chronic postoperative pain after total knee replacement (TKR) is approx. 20%, and hence preoperative risk factors are important to identify. Recent studies have indicated that preoperative inflammatory markers might hold prognostic information for the development of chronic postoperative pain. Read More

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gammaCore for Cluster Headaches: A NICE Medical Technologies Guidance.

Pharmacoecon Open 2021 Jul 28. Epub 2021 Jul 28.

Cedar, Cardiff and Vale University Health Board, Cardiff, UK.

Cluster headaches are excruciating attacks of pain that can last between 15 min and 3 h. Cluster headaches can be episodic, where patients have long pain-free intervals between attacks, or chronic, where they do not. As part of the Medical Technologies Evaluation Programme, the UK National Institute for Health and Care Excellence (NICE) considered the clinical effectiveness and cost impact of gammaCore (electroCore), a handheld, patient-controlled device used to treat and prevent cluster headache. Read More

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One-Year, Efficacy and Safety Open Label Study, with a Single Injection of a New Hyaluronan for Knee OA: The SOYA Trial.

J Pain Res 2021 21;14:2229-2237. Epub 2021 Jul 21.

Meiji Pharma Spain, Alcalá de Henares, Madrid, Spain.

Purpose: To assess the efficacy and safety of a single injection of a new formulation of hyaluronic acid (MPS-HA2%) in patients with symptomatic knee osteoarthritis after 12 months' follow-up.

Patients And Methods: Prospective, single-arm, multicentre, open-label, 12-month follow-up study. Patients with Kellgren-Lawrence (KL) 2-3 and visual analogue scale (VAS) pain scores of ≥40-< 80 mm received a single injection of MPS-HA2%. Read More

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Pain threshold, anxiety and other factors affect intensity of postoperative pain in gastric cancer patients: A prospective cohort study.

Chin J Cancer Res 2021 Jun;33(3):343-351

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Beijing 100142, China.

Objective: This prospective cohort study explored factors related to postoperative pain in gastric cancer patients.

Methods: A total of 236 patients who underwent gastrectomy were enrolled. All patients enrolled in the study completed the Hospital Anxiety and Depression Scale (HADS) questionnaire and Life Orientation Test-Revised (LOT-R) questionnaire on the day before surgery. Read More

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Comparison of effect of intraperitoneal instillation of additional dexmedetomidine or clonidine along with bupivacaine for post-operative analgesia following laparoscopic cholecystectomy.

Indian J Anaesth 2021 Jul 23;65(7):533-538. Epub 2021 Jul 23.

Department of Anaesthesiology and Critical Care Medicine, Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati, Andhra Pradesh, India.

Background And Aims: Despite advances in minimally invasive surgery, postoperative pain remains a concern after laparoscopic cholecystectomy. This study aims to compare the effect of intraperitoneal instillation of bupivacaine with alpha-2 agonists (dexmedetomidine and clonidine) for postoperative analgesia.

Methods: One hundred and eight patients scheduled for elective laparoscopic cholecystectomy were randomised to receive either 20 mL of 0. Read More

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Intensive care-treated cardiac arrest: a retrospective study on the impact of extended age on mortality, neurological outcome, received treatments and healthcare-associated costs.

Scand J Trauma Resusc Emerg Med 2021 Jul 28;29(1):103. Epub 2021 Jul 28.

Department of Emergency Care and Services, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Cardiac arrest (CA) is a leading cause of death worldwide. As population ages, the need for research focusing on CA in elderly increases. This study investigated treatment intensity, 12-month neurological outcome, mortality and healthcare-associated costs for patients aged over 75 years treated for CA in an intensive care unit (ICU) of a tertiary hospital. Read More

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Treatment of Renal Colic by Nerve Blockade with Lidocaine Versus Intravenous Dexketoprofen.

J Coll Physicians Surg Pak 2021 Aug;31(8):921-925

Department of Emergency Medicine, Kartal Dr. Lütfi Kırdar City Hospital, Istanbul, Turkey.

Objective: To compare non-steroidal anti-inflammatory drugs (NSAIDs) with spinal nerve blockade of related dermatomes using lidocaine for pain palliation of patients admitted to the Emergency Department (ED) with an episode of renal colic.

Study Design: Randomised controlled-trial.

Place And Duration Of Study: Department of Emergency Medicine, Kartal Dr. Read More

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Accommodative response to ocular surface pain.

Clin Exp Optom 2021 Jul 28:1-7. Epub 2021 Jul 28.

School of Optometry and Vision Science, University of Waterloo, Waterloo, Canada.

Clinical Relevance: The discovery of an accommodative response to ocular surface stimulation could inform clinicians and patients that optical effects may occur due to ocular discomfort and perhaps an assessment of the accommodative system after carrying out interventions impacting the ocular surface, may be warranted.

Background: There have been no previous reports evaluating the effect of noxious stimulation on accommodation. Here, the accommodative response of healthy participants after the application of noxious corneal stimulation is characterised. Read More

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The Effect of Postamputation Pain and Phantom Sensations on Prosthesis Use, Body Image, and Quality of Life in Patients with Lower-extremity Amputation.

Agri 2021 Jul;33(3):183-189

Istanbul Physical Medicine And Rehabilitation Training And Research Hospital, Istanbul, Turkey.

Objective: The aim of this study was to investigate phantom limb pain (PLP), phantom limb sensation (PLS), and residual limb pain (RLP) after lower-extremity amputation and their effect on patients' effective prosthesis use, body image, and quality of life in prosthetic users.

Methods: Fifty-seven patients with lower-extremity amputation who used prosthesis for at least three months were included in our study. PLP, PLS, and RLP were evaluated via the prosthesis evaluation questionnaire (PEQ). Read More

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