2,263 results match your criteria pain emergence

Case Report: Virtual Reality Neurofeedback Therapy as a Novel Modality for Sustained Analgesia in Centralized Pain Syndromes.

Front Psychiatry 2021 20;12:660105. Epub 2021 Apr 20.

Transitional Year Program, Garnet Health Medical Center, Middletown, NY, United States.

Neurofeedback (NFB) Therapy is a form of biofeedback, using the electroencephalogram (EEG) that has been in use since the 1970s, serving as a non-pharmacological intervention for epilepsy and psychiatric conditions such as anxiety, depression, insomnia, PTSD, post-concussive syndrome, and now, centralized pain. Chronic pain can increase neuronal activity and eventually causes poor modulation of pain messages. With the emergence of Virtual Reality (VR) in acute pain management, and the contraindications of opioids in chronic pain, applying novel biotechnologies seems like the next frontier in multimodal pain management. Read More

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Clinical Perspectives of Multiple and Extensively Drug-Resistant Typhoid; result from a tertiary care hospital from Pakistan.

J Infect Dev Ctries 2021 Apr 30;15(4):530-537. Epub 2021 Apr 30.

Department of Medicine, Combined Military Hospital Lahore Medical College, Lahore, Pakistan.

Introduction: Typhoid fever remains a problem in developing countries, including Pakistan. The emergence of multidrug-resistant and, since 2016, of extensively drug-resistant cases is a continuous challenge for health care workers. The COVID-19 pandemic is making management more difficult. Read More

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Towards and beyond the Pillars of Hercules: Integration and transformation of destructiveness in child psychosis (the case of Amine).

Luca Quagelli

Int J Psychoanal 2019 Jun;100(3):481-504

CMPP M. Winburn, Courbevoie, France.

Drawing on detailed clinical material taken from the first two years of the psychotherapy of Amine, a six-year-old psychotic child, the author shows how the destructiveness of the most extreme clinical realities can be transformed and integrated in the course of the treatment. During the first period of the treatment, the patient's continuity of being was missing and he could not control his body and actions. In this situation, destructiveness was Amine's only way to express and communicate the devastation of his inner world. Read More

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Comparison of remifentanil concentrations with and without dexmedetomidine for the prevention of emergence cough after nasal surgery: a randomized double-blinded trial.

BMC Anesthesiol 2021 May 4;21(1):136. Epub 2021 May 4.

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon, 16499, South Korea.

Background: Preventing emergence cough after nasal surgery is critical. Emergence cough can provoke immediate postoperative bleeding, which leads to upper airway obstruction. In the present study, we compared the effect-site concentration (Ce) of remifentanil to prevent emergence cough after propofol anesthesia for nasal surgery when remifentanil was or was not combined with dexmedetomidine. Read More

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The Effects of Intraoperative Caffeine on Postoperative Opioid Consumption and Related Outcomes After Laparoscopic Surgery: A Randomized Controlled Trial.

Anesth Analg 2021 May 3. Epub 2021 May 3.

From the Department of Anesthesiology.

Background: Surgical patients are vulnerable to opioid dependency and related risks. Clinical-translational data suggest that caffeine may enhance postoperative analgesia. This trial tested the hypothesis that intraoperative caffeine would reduce postoperative opioid consumption. Read More

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Year in Review 2020: Noteworthy Literature in Cardiothoracic Anesthesiology.

Semin Cardiothorac Vasc Anesth 2021 May 3:10892532211013614. Epub 2021 May 3.

University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

The year 2020 was marred by the emergence of a deadly pandemic that disrupted every aspect of life. Despite the disruption, notable research accomplishments in the practice of cardiothoracic anesthesiology occurred in 2020 with an emphasis on optimizing care, improving outcomes, and expanding what is possible for patients undergoing cardiac surgery. This year's edition of Noteworthy Literature Review will focus on specific themes in cardiac anesthesiology that include preoperative anemia, predictors of acute kidney injury following cardiac surgery, pain management modalities, anticoagulation strategies after transcatheter aortic valve replacement, mechanical circulatory support, and future directions in research. Read More

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Shoulder arthroplasty in dwarfism: A case report of pseudoachondroplasia with 17-year follow-up.

Orthop Rev (Pavia) 2021 Mar 31;13(1):8605. Epub 2021 Mar 31.

Shoulder Service, Massachusetts General Hospital, Boston, MA, USA.

The purpose of this case report is to report the long-term outcome following shoulder hemiarthroplasty in a patient with dwarfism. A 60-year old female with pseudoachondroplasia dwarfism presented 17 years post-operative with a Subjective Shoulder Value of 90% and minimal pain. Custom designed implants were critical for surgical success. Read More

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Effect-site concentration of remifentanil for smooth emergence from propofol-remifentanil anesthesia in patients using double lumen tube.

J Clin Anesth 2021 Apr 28;72:110297. Epub 2021 Apr 28.

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon-si, 16499, Gyeonggi-do, Republic of Korea. Electronic address:

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Efficacy of intranasal ketamine for acute pain management in adults: a systematic review and meta-analysis.

X Li G-C Hua F Peng

Eur Rev Med Pharmacol Sci 2021 Apr;25(8):3286-3295

Department of Pharmacy, Zaozhuang Municipal Hospital, Zaozhuang, Shandong Province, P.R. China.

Objective: This study aimed to compare the efficacy of intranasal (IN) ketamine for pain control with placebo and other analgesics in an emergency setting.

Materials And Methods: Electronic databases of PubMed, Embase, and CENTRAL were searched for randomized controlled trials (RCTs) comparing IN ketamine with placebo or other analgesics up to 1st January 2021. Studies were to be conducted on adults and in an emergency setting. Read More

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Application of Laparoscopy in Comprehensive Staging Operation of Ovarian Cancer Based on Electronic Medical Blockchain Technology.

J Healthc Eng 2021 7;2021:6649640. Epub 2021 Apr 7.

Department of Obstetrics and Gynecology, Affiliated Hospital of BeiHua University, Jilin, China.

Ovarian cancer has always entangled most women. Studies have shown that the prevalence of ovarian cancer ranks third in female reproductive malignancies, and the mortality rate has always been the highest. The reason is mainly because the diagnosis and treatment of preovarian cancer has always been a big problem. Read More

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Depressive Symptoms and Health-Related Quality of Life in Patients with Cardiovascular Diseases Attending a Tertiary Care Hospital, Puducherry-A Cross-Sectional Study.

J Neurosci Rural Pract 2021 Apr 23;12(2):376-381. Epub 2021 Apr 23.

Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Dhanvantri Nagar, Puducherry, India.

 Globally, coronary artery disease (CAD) was the leading cause of health losses. The emergence of revascularization has brought a major change in the management of CAD. Depression and cardiovascular diseases (CVD) are the two highly prevalent noncommunicable diseases (NCD), which lead to poor quality of life and high socio-economic loss for the patient. Read More

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(Poly-cyanoacrylate) nanomedicines for cancer and beyond: Lessons learned.

P Couvreur

J Control Release 2021 Apr 27;334:318-326. Epub 2021 Apr 27.

Institut Galien Paris-Sud, UMR 8612, CNRS, Univ Paris-Sud, Université Paris-Saclay, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry, Cedex, France.. Electronic address:

This « Magnum Opus » emphasizes that serendipity is a corner stone in research. The paths of discovery and innovation often result from the interdisciplinarity of scientific areas that are a priori disconnected from each other. In the 1970s, fundamental discoveries in cell biology led to unexpected advances in galenic pharmacy with the emergence of nanotechnologies for the intracellular delivery of non diffusing molecules. Read More

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Acute Intraoperative Hypoxemia During Right Pneumonectomy-The Heart and Lung Interaction: A Case Report.

A A Pract 2021 Apr 27;15(4):e01454. Epub 2021 Apr 27.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

A 75-year-old woman with a history of right-upper lobectomy for adenocarcinoma presented for a right completion pneumonectomy due to 2 new fluorodeoxyglucose-avid densities on the remaining lung. After uneventful anesthetic induction and surgical resection with modest blood loss, the patient developed refractory hypoxemia on emergence without significant hemodynamic changes. Despite delivery of fraction of inspired oxygen (Fio2) = 1. Read More

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Validation and characterization of oxycodone physical dependence in C57BL/6J mice.

Eur J Pharmacol 2021 Apr 23:174111. Epub 2021 Apr 23.

Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, 23298, USA; Translational Research Initiative for Pain and Neuropathy at VCU. Electronic address:

Opioid use disorder is a growing concern in the United States. Mice were used to investigate the mechanisms involving opioid physical dependence and for evaluating medications for treating opioid use disorders. While there are many preclinical reports describing protocols for inducing physical dependence upon morphine, there are fewer preclinical reports describing more contemporary abused prescription opiates. Read More

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Postoperative Maladaptive Behavior, Preoperative Anxiety and Emergence Delirium in Children Undergone General Anesthesia: A Narrative Review.

Glob Pediatr Health 2021 7;8:2333794X211007975. Epub 2021 Apr 7.

Universiti Sains Malaysia, School of Medical Sciences, Kubang Kerian, Kelantan, Malaysia.

Over the years, the number of pediatric patients undergoing surgeries are increasing steadily. The types of surgery vary between elective to emergency with involvement of multidisciplinary teams. The development of day care surgery unit is expanding where the patients will only come to the hospital on the day of surgery and discharge home after such as satisfactory parameters achieved, minimal to no pain, minimal to no bleeding from surgical site and able to tolerate fluids. Read More

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Pediatric emergence delirium is linked to increased early postoperative negative behavior within two weeks after adenoidectomy: an observational study.

Braz J Anesthesiol 2021 Apr 19. Epub 2021 Apr 19.

Klinikum Dortmund, Department of Anesthesiology and Operative Intensive Care Medicine, Dortmund, Germany; University Hospital Bonn, Department of Anesthesiology and Operative Intensive Care Medicine, Bonn, Germany. Electronic address:

Background: The aim of this prospective multicenter observational study was to measure the incidence of postoperative pediatric emergence delirium and to investigate the occurrence of early postoperative negative behavior within two weeks after outpatient adenoidectomy in preschool children.

Methods: The study comprised 222 patients (1-7 years of age). All children received a multimodal anesthesia based on total intravenous anesthesia with propofol and remifentanil in combination with piritramid (0. Read More

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The role of population-based cohorts in understanding the emergence and progression of musculoskeletal pain.

Pain 2021 Apr 19. Epub 2021 Apr 19.

Curtin School of Allied Health, Curtin University, Perth, Western Australia 6845, Australia Department of Health Science and Technology, Faculty of Medicine, Center for Neuroplasticity and Pain (CNAP), SMI, Aalborg University, Aalborg DK, Denmark. RECOVER Injury Research Centre, NHMRC Centre of Research Excellence in Road Traffic Injury, The University of Queensland, Herston, 4006, Australia Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland Finnish Institute of Occupational Health, Oulu, Finland.

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'Long COVID' syndrome.

BMJ Case Rep 2021 Apr 19;14(4). Epub 2021 Apr 19.

Royal Free London NHS Foundation Trust, London, UK.

SARS-CoV-2 has resulted in a global pandemic and an unprecedented public health crisis. Recent literature suggests the emergence of a novel syndrome known as 'long COVID', a term used to describe a diverse set of symptoms that persist after a minimum of 4 weeks from the onset of a diagnosed COVID-19 infection. Common symptoms include persistent breathlessness, fatigue and cough. Read More

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From acute to long-term alterations in pain processing and modulation after spinal cord injury: mechanisms related to chronification of central neuropathic pain.

Pain 2021 Apr 13. Epub 2021 Apr 13.

Department of Physical Therapy at Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University Department of Neurological Rehabilitation, Chaim Sheba Medical Center, Tel Hashomer Department of Rehabilitation Sackler Faculty of Medicine, Tel Aviv University Barzilai Medical Center, Ashkelon.

Abstract: A severe and debilitating consequence of a spinal cord injury (SCI) is central neuropathic pain (CNP). Our aim was to investigate the processes leading to CNP emergence and chronification by analyzing causal relationship over time between spinothalamic function, pain excitability, and pain inhibition after SCI.This longitudinal follow-up study included 53 patients with acute SCI and 20 healthy controls. Read More

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From One Pain to Many: The Emergence of Overlapping Pains in Children and Adolescents.

Clin J Pain 2021 Jun;37(6):404-412

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital and Harvard Medical School.

Objectives: The objective of this study was to compare children and adolescents with overlapping chronic pains (OCP) to those with single chronic pains (SCP) among youth presenting in specialized clinical settings, in an effort to identify potential risk factors for developing overlapping pains.

Methods: A total of 1235 youth ages 8 to 18 seen in a tertiary care multidisciplinary pain clinic or a multidisciplinary headache clinic completed self-report measures of pain, disability, psychological functioning and clinical history and characteristics at the time of initial clinic visit. Information was captured in a chronic pain data repository and accessed for the current study. Read More

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The Neural Circuits Underlying General Anesthesia and Sleep.

Anesth Analg 2021 05;132(5):1254-1264

From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

General anesthesia is characterized by loss of consciousness, amnesia, analgesia, and immobility. Important molecular targets of general anesthetics have been identified, but the neural circuits underlying the discrete end points of general anesthesia remain incompletely understood. General anesthesia and natural sleep share the common feature of reversible unconsciousness, and recent developments in neuroscience have enabled elegant studies that investigate the brain nuclei and neural circuits underlying this important end point. Read More

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Expert consensus of Chinese Association for the Study of Pain on the non-opioid analgesics for chronic musculoskeletal pain.

World J Clin Cases 2021 Mar;9(9):2068-2076

Department of Algology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.

Chronic musculoskeletal pain (CMP) is a common occurrence in clinical practice and there are a variety of options for the treatment of it. However, the pharmacological therapy is still considered to be a primary treatment. The recent years have witnessed the emergence of opioid crisis, yet there are no relevant guidelines on how to treat CMP with non-opioid analgesics properly. Read More

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Persistent Joint Pain Following Arthropod Virus Infections.

Curr Rheumatol Rep 2021 Apr 13;23(4):26. Epub 2021 Apr 13.

Department of Medicine, George Washington University, 2150 Pennsylvania Ave Suite 5-416, Washington, DC, 20037, USA.

Purpose Of Review: Persistent joint pain is a common manifestation of arthropod-borne viral infections and can cause long-term disability. We review the epidemiology, pathophysiology, diagnosis, and management of arthritogenic alphavirus infection.

Recent Findings: The global re-emergence of alphaviral outbreaks has led to an increase in virus-induced arthralgia and arthritis. Read More

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Dexmedetomidine decreased the post-thyroidectomy bleeding by reducing cough and emergence agitation - a randomized, double-blind, controlled study.

BMC Anesthesiol 2021 Apr 12;21(1):113. Epub 2021 Apr 12.

Department of Anesthesiology and Pain Medicine, Chosun University Hospital, 365 Pilmun-dearo, Donggu, 61453, Gwangju, Korea.

Background: Bleeding after thyroidectomy occurs due to violent coughing during emergence. Dexmedetomidine is helpful for the smooth emergence and suppression of cough. The purpose of the present study was to compare the effects of dexmedetomidine on postoperative bleeding after thyroidectomy. Read More

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The latest trend in neuromuscular monitoring: return of the electromyography.

Wonjin Lee

Anesth Pain Med (Seoul) 2021 Apr 12;16(2):133-137. Epub 2021 Apr 12.

Department of Anesthesiology and Pain Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

To reduce the risk of residual neuromuscular blockade, neuromuscular monitoring must be performed. Acceleromyography (AMG)-based neuromuscular monitoring was regarded as "clinical gold standard" and widely applied. However, issues related to patient's posture and overestimation of train-of-four ratio associated with AMG-based neuromuscular monitoring have increased. Read More

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Emerging wearable technology applications in gastroenterology: A review of the literature.

World J Gastroenterol 2021 Mar;27(12):1149-1160

Department of Psychiatry and Biobehavioral Sciences, Olive View - University of California Los Angeles Medical Center, Sylmar, CA 91342, United States.

The field of gastroenterology has recently seen a surge in wearable technology to monitor physical activity, sleep quality, pain, and even gut activity. The past decade has seen the emergence of wearable devices including Fitbit, Apple Watch, AbStats, and ingestible sensors. In this review, we discuss current and future devices designed to measure sweat biomarkers, steps taken, sleep efficiency, gastric electrical activity, stomach pH, and intestinal contents. Read More

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Impact of SARS-CoV-2 pandemic on emergency department activity at the pediatric surgery unit of a third-level hospital.

Cir Pediatr 2021 Apr 1;34(2):85-89. Epub 2021 Apr 1.

Pediatric Surgery Unit. La Paz Pediatric Hospital, Madrid (Spain). La Paz Biomedical Research Institute (IdiPaz), Maternal, Child, and Development Health (SAMID) network.

Introduction: As a result of the emergence of the SARS-CoV-2 respiratory virus in Wuhan in December 2019, the Spanish Government declared the state of emergency with restrictions such as stay-at-home lockdown. The objective of this study was to analyze emergency activity at a referral pediatric surgery unit in its territory and determine whether surgical pathologies had decreased or not.

Methods: A retrospective study of pediatric patients presenting at the emergency department and referred to the pediatric surgery unit from March 14, 2020 to April 20, 2020 was carried out. Read More

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Simultaneous comparison of depth of sedation performance between SedLine and BIS during general anesthesia using custom passive interface hardware: study protocol for a prospective, non-blinded, non-randomized trial.

BMC Anesthesiol 2021 Apr 6;21(1):105. Epub 2021 Apr 6.

Department of Anesthesiology and Pain Medicine, University of California Davis Medical Center, 4150 V Street, PSSB Suite 1200, Sacramento, CA, 95817, USA.

Background: Intraoperative brain function monitoring with processed electroencephalogram (EEG) indices, such as the bispectral index (BIS) and patient state index (PSI), may improve characterization of the depth of sedation or anesthesia when compared to conventional physiologic monitors, such as heart rate and blood pressure. However, the clinical assessment of anesthetic depth may not always agree with available processed EEG indices. To concurrently compare the performance of BIS and SedLine monitors, we present a data collection system using shared individual generic sensors connected to a custom-built passive interface box. Read More

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Aortic Pathology During COVID - 19 Pandemics. Clinical Reports in Literature and Open Questions on the two Co-Occurring Conditions.

Ann Vasc Surg 2021 Apr 3. Epub 2021 Apr 3.

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.

Background: Cardiovascular involvement in SARS-CoV-2 infection has emerged as one of viral major clinical features during actual pandemic; limb arterial ischemic events, venous thrombosis, acute myocardial infection and stroke have occurred in patients. Acute aortic conditions have also been described, followed by interesting observations on cases, hypothesis, raised since the emergence of the pandemics.

Methods: a review of cases in literature of aortic pathology in patients with clinically suspected/microbiologically confirmed COVID-19 infection has been carried out to analyze anagraphic data, clinical presentation, treatment options and outcome. Read More

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