11,332 results match your criteria pain dyspnea


Successful management of severe allergic reactions to platelet transfusion with omalizumab: A case report.

Medicine (Baltimore) 2021 Nov;100(44):e27724

Department of Hematology and Oncology, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.

Rationale: An allergic transfusion reaction is a common side effect of transfusions of red blood cells. Using washed red blood cells is the most effective method for preventing such a reaction. However, the availability of other washed transfusion components, including platelets, is limited. Read More

View Article and Full-Text PDF
November 2021

Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers.

Rev Esp Cardiol (Engl Ed) 2021 Nov 5. Epub 2021 Nov 5.

Servicio de Cardiología, Hospital Universitario de Salamanca, Salamanca, Spain; Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), Spain; Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain; Facultad de Medicina, Universidad de Salamanca, Salamanca, Spain. Electronic address:

Introduction And Objectives: The cardiac sequelae of SARS-CoV-2 infection are still poorly documented. We conducted a cross-sectional study in healthcare workers to report evidence of pericardial and myocardial involvement after SARS-CoV-2 infection.

Methods: We studied 139 healthcare workers with confirmed past SARS-CoV-2 infection. Read More

View Article and Full-Text PDF
November 2021

[Electronic cigarette use-associated lung injury: a case report and literature review].

Zhonghua Jie He He Hu Xi Za Zhi 2021 May;44(5):481-487

Department of Respiratory and Critical Care Medicine,Beijing Hospital National Center of Gerontology,Institute of Geriatric Medcine, Chinese Academy of Medical Science, Beijing 100730,China.

To improve the clinical recognition of electronic cigarette or vaping product use-associated lung injury. A 67 year old patient with lung injury induced by e-cigarette was reported. The concentrations of vitamin E acetate (VEA) and tetrahydrocannabinol (Δ9-THC) in BALF were measured by UHPLC-MS/MS. Read More

View Article and Full-Text PDF

Aortic Size and Clinical Care Pathways Before Type A Aortic Dissection.

Am J Cardiol 2021 Nov 30. Epub 2021 Nov 30.

Minneapolis Heart Institute Foundation and Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota. Electronic address:

Patients with aortic enlargement are recommended to undergo serial imaging and clinical follow-up until they reach surgical thresholds. This study aimed to identify aortic diameter and care of patients with aortic imaging before aortic dissection (AD). In a retrospective cohort of AD patients, we evaluated previous imaging results in addition to ordering providers and indications. Read More

View Article and Full-Text PDF
November 2021

A spear to the heart-the accidental discovery of a giant cement embolism in the right heart: a case report.

Eur Heart J Case Rep 2021 Nov 25;5(11):ytab336. Epub 2021 Aug 25.

Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.

Background: The incidence of recognized cardiopulmonary cement embolism in the context of percutaneous vertebroplasty varies between 0% and 23%. In most cases, only small fragments embolize in the pulmonary arteries or the right heart cavities. The latter can cause potential harm by right ventricular perforation. Read More

View Article and Full-Text PDF
November 2021

Acute Coronary Syndrome or Right Atrial Cardiac Myxoma? An Atypical Presentation.

Cureus 2021 Oct 29;13(10):e19116. Epub 2021 Oct 29.

Cardiology, Lower Bucks Hospital, Bristol, USA.

The size and location of cardiac tumors determine how patients present with signs of heart failure due to diminished cardiac output within the circulatory system. Poor cardiac output presents with signs of heart failure, which include pulmonary edema, lower extremity edema, jugular venous distention, dyspnea, orthopnea and can be insidious in onset. Vital signs on presentation can often be abnormal and patients may present hemodynamically unstable. Read More

View Article and Full-Text PDF
October 2021

Systemic Sclerosis in Zimbabwe: Autoantibody Biomarkers, Clinical, and Laboratory Correlates.

Front Immunol 2021 9;12:679531. Epub 2021 Nov 9.

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

Introduction: Systemic sclerosis (SScl) is an autoimmune disease whose prevalence is rarely reported in Africa. Autoantibodies are the biomarkers of the condition, precede overt disease and determine disease phenotypes. SSc specific autoantibodies also vary between racial groupings. Read More

View Article and Full-Text PDF
November 2021

Do Anxiety and Depression Predict Persistent Physical Symptoms After a Severe COVID-19 Episode? A Prospective Study.

Front Psychiatry 2021 10;12:757685. Epub 2021 Nov 10.

Service de Microbiologie, Unité Mobile d'Infectiologie, Assistance Publique Hopitaux De Paris, Hôpital Européen Georges Pompidou, Université de Paris, Paris, France.

Persistent physical symptoms are common after a coronavirus disease 2019 (COVID-19) episode, but their pathophysiological mechanisms remain poorly understood. In this study, we aimed to explore the association between anxiety and depression at 1-month after acute infection and the presence of fatigue, dyspnea, and pain complaints at 3-month follow-up. We conducted a prospective study in patients previously hospitalized for COVID-19 followed up for 3 months. Read More

View Article and Full-Text PDF
November 2021

Massive pericardial effusion as the first manifestation of childhood non-Hodgkin's lymphoma: A case report.

Clin Case Rep 2021 Nov 25;9(11):e05105. Epub 2021 Nov 25.

Pediatric Pathologist Mashhad University of Medical Sciences Mashhad Iran.

Although one of the serious manifestations of advanced malignancies is pericardial involvement, pericardial involvement of lymphoma is extremely rare. We present a case of a 6-year-old girl arriving at the hospital with dyspnea and pleuritic chest pain, which is eventually diagnosed with massive pericardial effusion due to mediastinal non-Hodgkin lymphoma. Read More

View Article and Full-Text PDF
November 2021

Para-aortic lymphadenopathy associated with adult COVID-19 multisystem inflammatory syndrome.

BMJ Case Rep 2021 Dec 1;14(12). Epub 2021 Dec 1.

Unidade de Terapia Intensiva, Hospital Niteroi D'Or, D'Or São Luiz Network, Niterói, Brazil.

A 21-year-old woman arrived at the emergency department with dyspnoea, arterial hypotension and abdominal pain after 5 days with a influenza-like syndrome. SARS-CoV-2 was detected by reverse transcription PCR in a nasopharyngeal swab specimen. CT of the chest and abdomen with contrast demonstrated a minimal amount of free intraperitoneal fluid, gallbladder with wall oedema, multiple para-aortic lymph node and interlobular septal thickening with ground glass opacities on the lungs. Read More

View Article and Full-Text PDF
December 2021

Emphysematous gastritis associated with mucormycosis in a patient with fulminant myocarditis requiring veno-arterial extracorporeal membrane oxygenation.

Rev Esp Enferm Dig 2021 12 2. Epub 2021 Dec 2.

Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University.

We present the case of a 37-year-old male who admitted to our hospital with fever, weakness, limb pain for 6 days and dyspnea for 14 hours .The patient had no immune related diseases.He was rapidly diagnosed with fulminant myocarditis and progressed to severe cardiogenic shock during the early stage. Read More

View Article and Full-Text PDF
December 2021

Functional Disability Among Systemic Sclerosis Patients: Relation to Disease Characteristics and Quality of Life Parameters.

Curr Rheumatol Rev 2021 Nov 30. Epub 2021 Nov 30.

Rheumatology and Rehabilitation Department, Faculty of Medicine, Zagazig University. Egypt.

Background: Disability in patients with scleroderma (SSc) has been associated with poor health-related quality of life (HRQoL) in all dimensions, including physical, psychological, and social dimensions.

Objective: This study was conducted to examine different factors that may be associated with functional disability and poor HRQoL, with the aim of targeting these factors in the future to improve physical activity, functional outcomes, and HRQoL.

Methods: A single-center cross-sectional study was conducted on 38 patients with SSc to compare characteristics between patients with and without disability using the Health Assessment Questionnaire Disability Index (HAQ-DI). Read More

View Article and Full-Text PDF
November 2021

A Scoping Review of Palliative Care for Adults with Huntington's Disease: Current Practice and Future Directions.

J Palliat Med 2021 Nov 30. Epub 2021 Nov 30.

Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA.

Huntington's disease (HD) is a neurodegenerative disorder characterized by mid-life onset, cognitive decline, and behavioral disturbance. We conducted a review of the end-of-life (EOL) experience of HD patients and their families. We searched 5 electronic databases. Read More

View Article and Full-Text PDF
November 2021

Removal of a Giant Cyst of the Left Ovary from a Pregnant Woman in the First Trimester by Laparoscopic Surgery under Spinal Anesthesia during the COVID-19 Pandemic.

Med Sci (Basel) 2021 11 13;9(4). Epub 2021 Nov 13.

Department of Gynecology & Obstetrics, University Hospital of Geneva, CH-1205 Geneva, Switzerland.

This paper reports a case of a 21 year old primigravida at 6 weeks gestation, suffering from important abdominal pain, who was admitted into the medical center with a giant cyst of 28 × 20 cm on her left ovary. A torsion of the ovarian cyst was suspected. Her COVID-19 status was unknown. Read More

View Article and Full-Text PDF
November 2021

Liver abscess with necrosis in post COVID-19: A case report.

Ann Med Surg (Lond) 2021 Dec 23;72:103107. Epub 2021 Nov 23.

Intensive Care Unit, Columbia Asia Hospital, Semarang, Indonesia.

Introduction: Coronavirus disease 2019 (COVID-19) is an acute respiratory tract infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). Recent evidences mentioned the possibility of COVID-19 as a systemic infectious and inflammatory disease. Signs and symptoms of liver and gastrointestinal system are often found in post-acute COVID-19 patients. Read More

View Article and Full-Text PDF
December 2021

Two Cases of Bronchial Artery Racemose Hemangioma Successfully Treated with Bronchial Artery Embolization.

J Nippon Med Sch 2021 Nov 26. Epub 2021 Nov 26.

Department of Emergency and Critical Care Medicine, Nippon Medical School.

Rupture of a racemose hemangioma causing dilatation and tortuosity of the bronchial artery can result in massive bleeding and respiratory failure. Bronchial artery embolization (BAE) can treat this life-threatening condition, as we show in two cases. The first case was of an 89-year-old female complaining of sudden-onset chest and back pain. Read More

View Article and Full-Text PDF
November 2021

[Exploration of Distress Symptoms and Medical Interventions in Patients With Terminal Cancer in Hospice Shared Care].

Hu Li Za Zhi 2021 Dec;68(6):32-42

PhD, RN, Professor, School of Nursing, Chang Gung University, Taiwan, ROC.

Background: Hospice shared care is a model of care widely used in patients with terminal cancer. Appropriate interventions to improve related symptoms should be provided during disease progression through the end of life.

Purpose: The purpose of this study was to explore the related symptoms and to compare symptom severity before and after the implementation of hospice shared care and medical care interventions. Read More

View Article and Full-Text PDF
December 2021

Left sleeve pneumonectomy for a rare lung tumor: A case report.

Int J Surg Case Rep 2021 Oct 20;89:106528. Epub 2021 Oct 20.

Thoracic and Cardiovascular Surgery Department, Abderahmen Mami hospital, Tunis El Manar University, Tunisia.

Introduction And Importance: Primary adenoid cystic carcinoma (ACC) of the lung is extremely rare. This tumor can be asymptomatic or have non characteristics symptoms, and the diagnosis is often late. The treatment of choice is surgery when it's possible. Read More

View Article and Full-Text PDF
October 2021

COVID-19 outcomes among adult patients treated with long-term opioid therapy for chronic non-cancer pain in the USA: a retrospective cohort study.

BMJ Open 2021 11 26;11(11):e056436. Epub 2021 Nov 26.

Department of Family and Community Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA.

Objective: Patients treated with long-term opioid therapy (LTOT) are known to have compromised immune systems and respiratory function, both of which make them particularly susceptible to the SARS-CoV-2 virus. The objective of this study was to assess the risk of developing severe clinical outcomes among COVID-19 non-cancer patients on LTOT, compared with those without LTOT.

Design And Data Sources: A retrospective cohort design using electronic health records in the TriNetX research database. Read More

View Article and Full-Text PDF
November 2021

Treatment-Related Adverse Events with PD-1 or PD-L1 Inhibitors: A Systematic Review and Meta-Analysis.

Life (Basel) 2021 Nov 22;11(11). Epub 2021 Nov 22.

Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China.

Objective: to evaluate the risk of treatment-related adverse events of different severity and different system with PD-1 or PD-L1 inhibitors.

Methods: randomized controlled trials (RCTs) that using PD-1/PD-L1 for cancer treatment were searched in the PubMed, Embase, Cochrane Library, and Web of Science from 1 January 2019 to 31 May 2021. Adverse events data were extracted from clinical trials website or original article by two authors separately. Read More

View Article and Full-Text PDF
November 2021

Clinical Predictors of Mortality in Prehospital Distress Calls by Emergency Medical Service Subscribers.

J Clin Med 2021 Nov 17;10(22). Epub 2021 Nov 17.

Hadassah Medical Center, Cardiology Department, Faculty of Medicine, Hebrew University Jerusalem, Jerusalem 91905, Israel.

(1) Introduction: Most studies rely on in-hospital data to predict cardiovascular risk and do not include prehospital information that is substantially important for early decision making. The aim of the study was to define clinical parameters in the prehospital setting, which may affect clinical outcomes. (2) Methods: In this population-based study, we performed a retrospective analysis of emergency calls that were made by patients to the largest private emergency medical services (EMS) in Israel, SHL Telemedicine Ltd. Read More

View Article and Full-Text PDF
November 2021

Subclinical Myocardial Dysfunction in Patients Recovered from COVID-19 Disease: Correlation with Exercise Capacity.

Biology (Basel) 2021 Nov 18;10(11). Epub 2021 Nov 18.

The Heart Center, Kaplan Medical Center, Rehovot 7661041, Israel.

Aims: Myocardial abnormalities are common during COVID-19 infection and recovery. We examined left (LV) and right (RV) ventricular longitudinal strain in patients who had recovered from COVID-19 and assessed the correlation with exercise capacity.

Methods And Results: One hundred and eighty-four consecutive patients with history of COVID-19 disease who had been referred to rest or stress echocardiography because of symptoms, mainly dyspnea and chest pain, were included in the study. Read More

View Article and Full-Text PDF
November 2021

[Thoracolumbar back pain as the leading symptom of a marked COVID-19 pneumonia].

Dtsch Med Wochenschr 2021 Nov 26;146(23):1571-1575. Epub 2021 Nov 26.

Universitätsklinikum Leipzig AöR, Klinik und Poliklinik für Endokrinologie, Nephrologie und Rheumatologie, Leipzig.

History:  A 49-year-old male patient visited the surgical outpatient clinic with new onset low back pain. The pain was increasing for nine days and he did not have any signs of a respiratory infection, in particular neither fever nor cough.

Investigations:  During the further examination and unclothing, mild dyspnea was apparent. Read More

View Article and Full-Text PDF
November 2021

Bevacizumab-induced esophageal pleural fistula during maintenance therapy without radiation in lung cancer.

BMC Pulm Med 2021 Nov 25;21(1):384. Epub 2021 Nov 25.

Department of Respiratory Medicine, Xi'an People's Hospital (Xi'an No.4 Hospital), No.21 Jiefang Road, Xi'an, 710004, China.

Background: Esophageal pleural fistula (EPF) is a rare but fatal complication associated with bevacizumab use; however, cases reports of EPF caused by bevacizumab have not been previously published.

Case Presentation: A 66-year-old male patient diagnosed with stage IV lung adenocarcinoma on April 24, 2020 received 6 cycles of platinum-containing dual chemotherapy combined with bevacizumab followed by three cycles of bevacizumab monotherapy. Five days before admission, he experienced chest tightness, dyspnea, and right chest pain. Read More

View Article and Full-Text PDF
November 2021

Post-Acute Sequelae of COVID-19 and Cardiovascular Autonomic Dysfunction: What Do We Know?

J Cardiovasc Dev Dis 2021 Nov 15;8(11). Epub 2021 Nov 15.

Department of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, "G. d'Annunzio" University of Chieti-Pescara, Via Luigi Polacchi, 66100 Chieti, Italy.

Post-acute sequelae of SARS-CoV-2 (PASC), or long COVID syndrome, is emerging as a major health issue in patients with previous SARS-CoV-2 infection. Symptoms commonly experienced by patients include fatigue, palpitations, chest pain, dyspnea, reduced exercise tolerance, and "brain fog". Additionally, symptoms of orthostatic intolerance and syncope suggest the involvement of the autonomic nervous system. Read More

View Article and Full-Text PDF
November 2021

Underdiagnosis of cardiopulmonary involvement in patients with idiopathic inflammatory myopathies.

Reumatologia 2021 7;59(5):276-284. Epub 2021 Nov 7.

Department of Rheumatology, Medical University of Lodz, Poland.

Objectives: In the course of idiopathic inflammatory myopathies internal organs, including heart and lungs, can be involved. Cardiopulmonary complications significantly alter the course of the disease, leading to poorer prognosis. A lack of clear guidelines on the assessment of internal organ involvement in the course of myositis increases the risk of underdiagnosis. Read More

View Article and Full-Text PDF
November 2021

Persistent symptoms following SARS-CoV-2 infection among children and young people: a meta-analysis of controlled and uncontrolled studies.

J Infect 2021 Nov 20. Epub 2021 Nov 20.

Department of Child Life and Health, University of Edinburgh, UK; Royal Hospital for Children, Glasgow, UK. Electronic address:

Background: Data on the long-term impact of SARS-CoV-2 infection in children and young people (CYP) is conflicting. We assessed evidence on long-term post-COVID symptoms in CYP examining prevalence, risk factors, type and duration.

Methods: Systematic search of published and unpublished literature using 13 online databases between 01/12/2019 - 31/07/2021. Read More

View Article and Full-Text PDF
November 2021

Chlamydia pneumoniae-associated pleuropericarditis: a case report and systematic review of the literature.

BMC Pulm Med 2021 Nov 22;21(1):380. Epub 2021 Nov 22.

Third Department of Medicine, School of Medicine, National and Kapodistrian University of Athens, Sotiria Hospital, 152 Mesogion Avenue, 11527, Athens, Greece.

Background: Chlamydia pneumoniae is a common cause of atypical community acquired pneumonia (CAP). The diagnostic approach of chlamydial infections remains a challenge. Diagnosis of delayed chlamydial-associated complications, involving complex autoimmune pathophysiological mechanisms, is still more challenging. Read More

View Article and Full-Text PDF
November 2021

Constrictive pericarditis in the setting of repeated chest trauma in a mixed martial arts fighter.

BMC Cardiovasc Disord 2021 Nov 22;21(1):561. Epub 2021 Nov 22.

Division of Cardiovascular Medicine, Department of Medicine, University of Utah Health, 30 North 1900 East, Room 4A100, Salt Lake City, UT, 84132, USA.

Background: Constrictive pericarditis (CP) is characterized by scarring and loss of elasticity of the pericardium. This case demonstrates that mixed martial arts (MMA) is a previously unrecognized risk factor for CP, diagnosis of which is supported by cardiac imaging, right and left heart catheterization, and histological findings of dense fibrous tissue without chronic inflammation.

Case Presentation: A 47-year-old Caucasian male former mixed martial arts (MMA) fighter from the Western United States presented to liver clinic for elevated liver injury tests (LIT) and a 35-pound weight loss with associated diarrhea, lower extremity edema, dyspnea on exertion, and worsening fatigue over a period of 6 months. Read More

View Article and Full-Text PDF
November 2021

Efficacy of Inhaled Ciclesonide for Outpatient Treatment of Adolescents and Adults With Symptomatic COVID-19: A Randomized Clinical Trial.

JAMA Intern Med 2021 Nov 22. Epub 2021 Nov 22.

Medical College of Georgia at Augusta University, Augusta.

Importance: Systemic corticosteroids are commonly used in treating severe COVID-19. However, the role of inhaled corticosteroids in the treatment of patients with mild to moderate disease is less clear.

Objective: To determine the efficacy of the inhaled steroid ciclesonide in reducing the time to alleviation of all COVID-19-related symptoms among nonhospitalized participants with symptomatic COVID-19 infection. Read More

View Article and Full-Text PDF
November 2021