140 results match your criteria p < 001


In Vitro Antibiotic Resistance among Bacteria from the Cornea in the Antibiotic Resistance Monitoring in Ocular MicRoorganisms Surveillance Study.

Optom Vis Sci 2021 Sep 10. Epub 2021 Sep 10.

Educators in Primary Eye Care, LLC, Concord, North Carolina Charlotte Eye, Ear, Nose and Throat Associates, Charlotte, North Carolina Vita Eye Clinic, Shelby, North Carolina University of Tennessee Health Science Center, Knoxville, Tennessee

Purpose: This study aimed to report on in vitro susceptibility patterns among corneal isolates collected in the Antibiotic Resistance Monitoring in Ocular micRoorganisms (ARMOR) study.

Methods: Each year, from 2009 to 2019, Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates cultured from patients with ocular infections at participating ARMOR sites were submitted to a central laboratory for species confirmation and antibiotic susceptibility testing. In this analysis of corneal isolates, odds ratios for concurrent resistance were based on sample proportions, one-way ANOVA was used to evaluate resistance by patient age, and Cochran-Armitage tests were used to examine changes in antibiotic resistance over time. Read More

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September 2021

The Natural History, Growth Rates and Treatment of Popliteal Artery Aneurysms.

J Vasc Surg 2021 Sep 6. Epub 2021 Sep 6.

Department of Molecular Medicine and Surgery, Karolinska Institutet; Department of Vascular Surgery, Karolinska University Hospital, Stockholm, Sweden.

Introduction: The natural history of a cohort of patients under surveillance with popliteal artery aneurysms (PAA) is not well described. There is a prevailing uncertainty regarding optimal surveillance strategies and timing of treatment. The primary aim was to describe the care trajectory of all patients with PAA identified in two tertiary vascular centers, both in surveillance and eventually treated. Read More

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September 2021

Survival Analysis in Primary Progressive Apraxia of Speech and Agrammatic Aphasia.

Neurol Clin Pract 2021 Jun;11(3):249-255

Department of Radiology (JLW), Department of Health Sciences Research (PM), Division of Speech Pathology (JRD, HMC, RLU, EAS), and Division of Behavioral Neurology (HB, KAJ), Department of Neurology, and Department of Psychiatry and Psychology (MMM), Mayo Clinic, Rochester, MN.

Objective: To compare survival among patients with different combinations of apraxia of speech (AOS) and agrammatic aphasia, including those with isolated AOS (primary progressive AOS, PPAOS), both AOS and agrammatic aphasia (AOS + progressive agrammatic aphasia [PAA]), and isolated agrammatic aphasia (PAA).

Methods: One hundred nine patients were recruited who had any combination of AOS and agrammatic aphasia (42 PPAOS, 56 AOS + PAA, and 11 PAA) and were followed longitudinally, with 57 patients having since died. Cox proportional hazard models were used to quantify the relative risk of death across diagnoses. Read More

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The Value of Brain Resting-State Functional Magnetic Resonance Imaging on Image Registration Algorithm in Analyzing Abnormal Changes of Neuronal Activity in Patients with Type 2 Diabetes.

Contrast Media Mol Imaging 2021 13;2021:6951755. Epub 2021 Aug 13.

Department of Medical Imaging, Hebei Provincial People's Hospital, Shijiazhuang, Hebei 050051, China.

The aim of this paper was to analyze the application value of resting-state functional magnetic resonance imaging (FMRI) parameters and rigid transformation algorithm in patients with type 2 diabetes (T2DM), which could provide a theoretical basis for the registration application of FMRI. 107 patients confirmed pathologically as T2DM and 51 community medical healthy volunteers were selected and divided into an experimental group and a control group, respectively. Besides, all the subjects were scanned with FMRI. Read More

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L-carnitine protects DNA oxidative damage induced by phenylalanine and its keto acid derivatives in neural cells: a possible pathomechanism and adjuvant therapy for brain injury in phenylketonuria.

Metab Brain Dis 2021 Oct 3;36(7):1957-1968. Epub 2021 Jul 3.

Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Although phenylalanine (Phe) is known to be neurotoxic in phenylketonuria (PKU), its exact pathogenetic mechanisms of brain damage are still poorly known. Furthermore, much less is known about the role of the Phe derivatives phenylacetic (PAA), phenyllactic (PLA) and phenylpyruvic (PPA) acids that also accumulate in this this disorder on PKU neuropathology. Previous in vitro and in vivo studies have shown that Phe elicits oxidative stress in brain of rodents and that this deleterious process also occurs in peripheral tissues of phenylketonuric patients. Read More

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October 2021

Outcomes of popliteal artery aneurysms treated by ligation and in situ saphenous vein bypass.

Int Angiol 2021 Jun 18. Epub 2021 Jun 18.

Vascular and Endovascular Surgery Unit, Department of Surgery, San Giovanni di Dio Hospital, Florence, Italy.

Background: Modality of elective repair (open or endovascular) of popliteal artery aneurysms (PAAs) is still debated. About open repair no strict evidence exists about the best surgical technique. The aim of this study was to report a 20-year experience with ligation and in situ saphenous vein bypass for the elective treatment of PAAs. Read More

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Effect of various calcium hydroxide removal protocols on the dislodgement resistance of biodentine in an experimental apexification model.

J Dent Sci 2021 Jul 10;16(3):964-970. Epub 2020 Nov 10.

Department of Prosthodontics, Faculty of Dentistry, Near East University, Nicosia, Cyprus.

Background/purpose: Residual calcium hydroxide (CH) in the root canal dentine walls may influence the adhesion of tricalcium silicate-based materials. The aim of this study is to evaluate the effect of various CH removal protocols on the dislodgement resistance of biodentine from simulated immature root canals in an experimental apexification model.

Materials And Methods: CH was applied to 120 simulated immature root canals. Read More

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Extraction and electrochemical detection for quantification of trace-level DNA.

Mikrochim Acta 2021 05 5;188(6):180. Epub 2021 May 5.

Center of Excellence for Trace Analysis and Biosensor, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand.

A novel strategy was developed to extract, detect, and quantify trace-level DNA. For the extraction step, a composite of methylene blue (MB), poly(acrylic acid) (PAA), and modified iron oxide magnetic nanoparticles (IOMNPs) (PAA/IOMNPs) was used to adsorb DNA from the sample. MB-PAA/IOMNPs with adsorbed DNA were then separated from the solution with an external magnet and MB-DNA was eluted from PAA/IOMNPs with acetic acid. Read More

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Equivalency of peroxyacetic acid to chlorine as a shell egg sanitizing rinse.

Poult Sci 2021 Jun 18;100(6):101069. Epub 2021 Feb 18.

USDA Agricultural Research Service, US National Poultry Research Center, Egg Safety and Quality Research Unit, Athens, GA; Department of Poultry Science, University of Georgia, Athens, GA.

In the United States, all shell eggs processed under the USDA Agricultural Marketing Service voluntary grading standards must receive a shell sanitizing rinse of 100-200 ppm chlorine or its equivalent after leaving the washing process. A study was conducted to determine the concentration of peroxyacetic acid (PAA) which would be equivalent to 100-200 ppm chlorine (Cl) in reducing target organisms under the required washing conditions for shell eggs. Three isolates of Salmonella spp. Read More

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Peracetic acid-based disinfectant is the most appropriate solution for a biological decontamination procedure of responders and healthcare workers in the field environment.

J Appl Microbiol 2021 Sep 25;131(3):1240-1248. Epub 2021 Feb 25.

Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic.

Aims: An effective decontamination procedure of personnel wearing personal protective equipment is required by CBRN responders and healthcare workers when dealing with biological warfare agents or natural outbreaks caused by highly contagious pathogens. This study aimed to identify critical factors affecting the efficacy of peracetic acid (PAA)-based disinfectants and products containing either hydrogen peroxide or sodium hypochlorite under the same conditions.

Methods And Results: The influence of concentration, application (contact) time, erroneous human behaviour, interfering substance, technical assets and weather conditions on disinfection efficacy against Bacillus subtilis spores were assessed in 14 experimental groups. Read More

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September 2021

Final Endodontic Irrigation with 2% Peracetic Acid: Antimicrobial Activity and Cytotoxicity.

Eur J Dent 2021 Jul 3;15(3):533-538. Epub 2021 Feb 3.

Postgraduate Program in Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Rio de Janeiro, Brazil.

Objective:  The aim of present study was to assess the cytotoxicity and antimicrobial efficacy of 2% peracetic acid (PAA) compared with 5.25% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX).

Material And Methods:  For the cytotoxicity test, 100 µl of the tested solutions were added in 12 wells with ECV 304 endothelial cells in each group: NaOCl, CHX, and PAA, in addition to the control group. Read More

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A critical analysis of 57 cases of Hughes-Stovin syndrome (HSS). A report by the HSS International Study Group (HSSISG).

Int J Cardiol 2021 05 30;331:221-229. Epub 2021 Jan 30.

Clinical Department of Medical, Surgical and Health Science, University of Trieste, Piazzale Europa, 1, 34127 Trieste, TS, Italy.

Background: Hughes-Stovin syndrome (HSS) is a systemic disease characterized by widespread vascular thrombosis and pulmonary vasculitis with serious morbidity and mortality. The HSS International Study Group is a multidisciplinary taskforce aiming to study HSS, in order to generate consensus recommendations regarding diagnosis and treatment.

Methods: We included 57 published cases of HSS (43 males) and collected data regarding: clinical presentation, associated complications, hemoptysis severity, laboratory and computed tomography pulmonary angiography (CTPA) findings, treatment modalities and cause of death. Read More

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Prostatic ductal adenocarcinoma variant predicts worse pathological and oncological outcomes: Insight from over 1000 consecutive patients from a large prospective uro-oncology registry.

Prostate 2021 03 11;81(4):242-251. Epub 2021 Jan 11.

Department of Urology, Singapore General Hospital, Singapore.

Objective: To evaluate if prostatic ductal adenocarcinoma (PDA) independently predicts poorer pathological and oncological outcomes after radical prostatectomy (RP).

Methods And Materials: Utilizing a large prospective uro-oncology registry, clinicopathological parameters of 1027 consecutive patients who underwent RP (2008-2017) were recorded. Oncological outcomes were determined by failure to achieve unrecordable PSA postoperatively and biochemical failure (BCF). Read More

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Choroidal and peripapillary changes in high myopic eyes with Stickler syndrome.

BMC Ophthalmol 2021 Jan 4;21(1). Epub 2021 Jan 4.

Service d'Ophtalmologie, Ophtalmopôle de Paris, Hôpital Cochin, AP-HP, 27 rue du Faubourg Saint Jacques, 75014, Paris, France.

Background: To compare different clinical and Spectral-Domain Optical Coherence Tomography (SD-OCT) features of high myopic eyes with Stickler syndrome (STL) with matched controls.

Methods: Patients with genetically confirmed STL with axial length ≥ 26 mm and controls matched for axial length were included. The following data were obtained from SD-OCT scans and fundus photography: choroidal and retinal thickness (respectively, CT and RT), peripapillary atrophy area (PAA), presence of posterior staphyloma (PS). Read More

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January 2021

Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy.

J Immunother Cancer 2020 12;8(2)

Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Campania, Italy

Background: Inhibitors of immune checkpoint programmed cell death protein 1 (PD-1) receptor on T cells have shown remarkable clinical outcomes in metastatic melanoma. However, most patients are resistant to therapy. Production of extracellular adenosine, via CD73-mediated catabolism of AMP, contributes to suppress T-cell-mediated responses against cancer. Read More

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December 2020

Head acceleration event metrics in youth contact sports more dependent on sport than level of play.

Proc Inst Mech Eng H 2021 Feb 13;235(2):208-221. Epub 2020 Nov 13.

School of Mechanical Engineering, Purdue University, West Lafayette, IN, USA.

The goal of the study was to evaluate how repetitive head traumas sustained by athletes in contact sports depend on sport and level of play. A total of 16 middle school football players, 107 high school football players, and 65 high school female soccer players participated. Players were separated into levels of play: middle school (MS), freshman (FR), junior varsity (JV), junior varsity-varsity (JV-V), and varsity (V). Read More

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February 2021

Chronic Application of Low-Dose Aspirin Affects Multiple Parameters of Three Blood Cellular Types and Antithrombin Activity: A 1:1:1 Propensity Score Matching Analysis.

J Cardiovasc Pharmacol 2021 01;77(1):115-121

Department of Geriatric Cardiology, The Second Medical Center, The National Clinical Research Center for Geriatric Diseases, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China; and.

Abstract: The mechanisms of aspirin antithrombotic actions have not been fully elucidated. We re-analyzed the data from the project Aspirin Resistance in Patients with Ischemic Atherothrombotic Diseases from April 2008 to June 2010. A total of 530 subjects were classified into 3 groups, including 40 patients without aspirin use, 24 patients taking 25-50 mg/d aspirin, and 466 patients taking 75-100 mg/d aspirin over 1 month. Read More

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January 2021

Thin Porous Poly(ionic liquid) Coatings for Enhanced Headspace Solid Phase Microextraction.

Polymers (Basel) 2020 Aug 24;12(9). Epub 2020 Aug 24.

Centro de Química Estrutural and Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Avenida Rovisco Pais, 1049-001 Lisboa, Portugal.

In this contribution, thin poly(ionic liquid) (PIL) coatings with a well-defined pore structure built up from interpolyelectrolyte complexation between a PIL and poly(acrylic acid) (PAA) were successfully used for enhanced solid phase microextraction (SPME). The introduction of porosity with tunable polarity through the highly versatile PIL chemistry clearly boosts the potential of SPME in the detection of compounds at rather low concentrations. This work will inspire researchers to further explore the potential of porous poly(ionic liquid) materials in sensing and separation applications. Read More

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Contemporary Treatment of Popliteal Artery Aneurysms in 14 Countries: A Vascunet Report.

Eur J Vasc Endovasc Surg 2020 Nov 15;60(5):721-729. Epub 2020 Aug 15.

Department of Surgical Sciences, Section of Vascular Surgery, Uppsala, Sweden.

Objective: Popliteal artery aneurysm (PAA) is the second most common arterial aneurysm. Vascunet is an international collaboration of vascular registries. The aim was to study treatment and outcomes. Read More

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November 2020

Sol-Gel Synthesis, Physico-Chemical and Biological Characterization of Cerium Oxide/Polyallylamine Nanoparticles.

Polymers (Basel) 2020 Jun 28;12(7). Epub 2020 Jun 28.

Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran 144961-4535, Iran.

Cerium oxide nanoparticles (CeO-NPs) have great applications in different industries, including nanomedicine. However, some studies report CeO-NPs-related toxicity issues that limit their usage and efficiency. In this study, the sol-gel method was applied to the synthesis of CeO-NPs using poly(allylamine) (PAA) as a capping and/or stabilizing agent. Read More

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Cognitive and Quality of Life-Related Burdens of Illness in Pediatric Allergic Airway Disease.

Otolaryngol Head Neck Surg 2020 Apr 3;162(4):566-571. Epub 2020 Mar 3.

Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, Massachusetts, USA.

Objective: To analyze the prevalence of pediatric allergic airway disease (PAA) and recognize its impact on cognitive function, childhood activities, use of early intervention, and missed school days.

Study Design: Cross-sectional analysis of National Health Interview Survey (NHIS), 2014 to 2017.

Setting: US households. Read More

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Effect of Intra-operative Intra-arterial Thrombolysis on Long Term Clinical Outcomes in Patients with Acute Popliteal Artery Aneurysm Thrombosis.

Eur J Vasc Endovasc Surg 2020 02 6;59(2):255-264. Epub 2020 Jan 6.

Clinic for Vascular and Endovascular Surgery, Clinical Centre of Serbia, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

Objective: Acute lower limb ischaemia (ALI) as a result of popliteal artery aneurysm (PAA) thrombosis represents a significant problem. The aim of this study was to investigate outcome of intra-operative intra-arterial thrombolysis in the treatment of acute ischaemia due to PAA thrombosis in terms of major adverse limb events (MALE), overall survival, and intrahospital complications, especially those associated with bleeding.

Methods: A total of 156 patients with Rutherford grade IIa and IIb acute ischaemia resulting from PAA thrombosis were admitted between 1 January 2011 and 1 January 2017. Read More

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February 2020

Endovascular versus open repair of asymptomatic popliteal artery aneurysm.

Cochrane Database Syst Rev 2019 12 23;12:CD010149. Epub 2019 Dec 23.

Brighton and Sussex University Hospitals NHS Trust, Department of Interventional Radiology, Eastern Road, Brighton, UK, BN2 5BE.

Background: Popliteal artery aneurysm (PAA) is a focal dilatation and weakening of the popliteal artery. If left untreated, the aneurysm may thrombose, rupture or the clot within the aneurysm may embolise causing severe morbidity. PAA may be treated surgically by performing a bypass from the arterial segment proximal to the aneurysm to the arterial segment below the aneurysm, which excludes the aneurysm from the circulation. Read More

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December 2019

Ticagrelor in Patients with Stable Coronary Disease and Diabetes.

N Engl J Med 2019 Oct 1;381(14):1309-1320. Epub 2019 Sep 1.

From the French Alliance for Cardiovascular Trials, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Université de Paris, INSERM Unité 1148 (P.G.S.), Assistance Publique-Hôpitaux de Paris (P.G.S., T.S.), Hôpital Saint Antoine, Department of Clinical Pharmacology, Unité de Recherche Clinique (T.S.), and Sorbonne Université (T.S.) - all in Paris; the National Heart and Lung Institute, Imperial College and Royal Brompton Hospital, London (P.G.S., K.F.); Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School (D.L.B.) and Baim Institute for Clinical Research (Y.L.) - both in Boston; the Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, ON (S.R.M.), and Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.) - both in Canada; Stanford University, Stanford, CA (R.A.H.); the Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala (C.H.), and AstraZeneca BioPharmaceuticals Research and Development, Mölndal (M.A., A.H., W.R., M.L.-Z.) - both in Sweden; the Department of Cardiology, Medical University of Warsaw, Warsaw, Poland (G.O.); City Clinical Hospital No. 51, State Health Care Agency, Moscow (D.Z.); Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China (J.G.); Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (J.C.N.); Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile (R.C.); Northwest Clinics, Department of Cardiology, Alkmaar, Dutch Network for Cardiovascular Research, Utrecht, and Department of Cardiology, Radboud University Medical Center, Nijmegen - all in the Netherlands (J.H.C.); and Cardiocenter Charles University, Third Faculty of Medicine, University Hospital Kralovske Vinohrady, Prague, Czech Republic (P.W.).

Background: Patients with stable coronary artery disease and diabetes mellitus who have not had a myocardial infarction or stroke are at high risk for cardiovascular events. Whether adding ticagrelor to aspirin improves outcomes in this population is unclear.

Methods: In this randomized, double-blind trial, we assigned patients who were 50 years of age or older and who had stable coronary artery disease and type 2 diabetes mellitus to receive either ticagrelor plus aspirin or placebo plus aspirin. Read More

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October 2019

Quantification of urinary derivatives of Phenylbutyric and Benzoic acids by LC-MS/MS as treatment compliance biomarkers in Urea Cycle disorders.

J Pharm Biomed Anal 2019 Nov 1;176:112798. Epub 2019 Aug 1.

Group of Metabolism, Biocruces Bizkaia Health Research Institute, linked clinical group of Rare Diseases CIBER (CIBERER), Barakaldo, Spain. Electronic address:

Purpose: Salts of phenylacetic acid (PAA) and phenylbutyric acid (PBA) have been used for nitrogen elimination as a treatment for hyperammonaemia caused by urea cycle disorders (UCD). A new analytical method for PBA measurement in urine which helps to evaluate the drug adherence has been implemented.

Methods: Urine specimens from UCD patients receiving PBA were analysed by tandem mass spectrometry to measure urine phenylacetylglutamine (PAGln). Read More

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November 2019

In Vivo Morphological Changes of the Femoropopliteal Arteries due to Knee Flexion After Endovascular Treatment of Popliteal Aneurysm.

J Endovasc Ther 2019 08 14;26(4):496-504. Epub 2019 Jun 14.

5 Department of Civil Engineering and Architecture, University of Pavia, Italy.

To evaluate morphological changes of the femoropopliteal (FP) arteries due to limb flexion in patients undergoing endovascular treatment of popliteal artery aneurysms (PAAs). Seven male patients (mean age 68 years) underwent endovascular treatment of PAA with a Viabahn stent-graft between January 2013 and December 2017. During follow-up, one contrast-enhanced computed tomography angiography (CTA) scan of the lower limbs was acquired for each recruited patient. Read More

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The Anomalous Influence of Polyelectrolyte Concentration on the Deposition and Nanostructure of Poly(ethyleneimine)/Poly(acrylic acid) Multilayers.

Authors:
Martin Müller

Molecules 2019 Jun 6;24(11). Epub 2019 Jun 6.

Department Polyelectrolytes and Dispersions, Leibniz-Institut für Polymerforschung Dresden e.V., Hohe Str. 6, 01069 Dresden, Germany.

The deposition and nanostructure of polyelectrolyte (PEL) multilayers (PEMs) of branched poly(ethyleneimine)/poly(acrylic acid) (PEI/PAA) onto silicon substrates was studied in terms of the dependence of pH and the PEL concentration (c) in the individual adsorption steps z. Both a commercial automatic dipping device and a homebuilt automatic stream coating device (flow cell) were used. Gravimetry, SFM, transmission (TRANS) and in situ attenuated total reflection (ATR) FTIR spectroscopy were used for the quantitative determination of the adsorbed amount, thickness, chemical composition and morphology of deposited PEMs, respectively. Read More

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Postapplication Advisement for U.S. Medical School Reapplicants: One School's Program.

Acad Med 2019 05;94(5):688-691

M.P. Ballejos is assistant professor and vice chair of diversity, equity and inclusion, Department of Family and Community Medicine, and assistant dean for admissions, University of New Mexico School of Medicine, Albuquerque, New Mexico; ORCID: http://orcid.org/0000-0002-6288-1849. C.L. Schmitt is senior statistician, Department of Family and Community Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico. K.L. McKinney is research specialist, Department of Family and Community Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico. R. Sapien is distinguished professor, Departments of Emergency Medicine and Pediatrics, and associate dean for admissions, University of New Mexico School of Medicine, Albuquerque, New Mexico.

Problem: Reapplicants make up over one-quarter of U.S. medical school applicants. Read More

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Testing psychometric properties of a new instrument 'Promoting Active Ageing in Older People with Mental Disorders Scale' from a cross-sectional study.

Psychogeriatrics 2019 Jul 19;19(4):370-383. Epub 2019 Feb 19.

School of Nursing and Midwifery, The University of Newcastle, Callaghan, New South Wales, Australia.

Background: There is no instrument that measures the promotion of active ageing or the factors that influence the promotion of active ageing in older people with mental disorders living in the community. This study aimed to examine psychometric properties of a new survey instrument.

Methods: A mixed methods exploratory sequential design was used incorporating a cross-sectional survey. Read More

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Prospective assessment of health-related quality of life after endovascular repair of pararenal and thoracoabdominal aortic aneurysms using fenestrated-branched endografts.

J Vasc Surg 2019 05 24;69(5):1356-1366.e6. Epub 2018 Oct 24.

Mayo Clinic Aortic Center, Advanced Endovascular Aortic Research Program, Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, Minn. Electronic address:

Objective: The objective of this study was to investigate changes in health-related quality of life (QOL) in patients treated for pararenal aortic aneurysms (PAAs) and thoracoabdominal aortic aneurysms (TAAAs) with fenestrated-branched endovascular aneurysm repair (F-BEVAR).

Methods: A total of 159 consecutive patients (70% male; mean age, 75 ± 7 years) were enrolled in a prospective, nonrandomized single-center study using manufactured F-BEVAR (2013-2016). All patients were observed for at least 12 months (mean follow-up time, 27 ± 12 months). Read More

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