J Control Release 2022 Jun 22. Epub 2022 Jun 22.
Former President of Japan Society of Drug Delivery System, 5-3-13, Otsuka, Bunkyo-ku, Tokyo, 112-0012, Japan, Visiting Scientist, Department of Immune Medicine, National Cancer Center Research Institute 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:
In May 2021, 35 years after first announcing the enhanced permeability and retention (EPR) effect, Dr. Maeda passed away. As a theoretical pillar of high molecular weight drug delivery systems (DDS) with high biocompatibility, the EPR effect has been proven worldwide in experimental mouse models. Read More