25,987 results match your criteria ovarian cysts

Ovarian endosalpingiosis mimicking hydrosalpinges. Unexpected intraoperative findings and a diagnostic rollercoaster.

J Surg Case Rep 2021 Jun 29;2021(6):rjab264. Epub 2021 Jun 29.

Obstetrics and Gynaecology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.

Over 80 % of ovarian cancer diagnoses are in women aged over 50 years. Post-menopausal women are at significantly increased risk compared with other age groups. Tumour biomarkers and ultrasound assist with diagnostics. Read More

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Importance of Potential New Biomarkers in Patient with Serouse Ovarian Cancer.

Diagnostics (Basel) 2021 Jun 3;11(6). Epub 2021 Jun 3.

Department of Physiology, Pomeranian Medical University, Powstańców Wlkp. 72, 70-111 Szczecin, Poland.

Ovarian cancer remains the gynecological cancer with the highest mortality rate. In our study, we compare a number of proteins from different effector pathways to assess their usefulness in the diagnosis of ovarian cancer. The tissue expression of the tested proteins was assessed by two methods: qRT-PCR and an immunohistochemical analysis. Read More

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Ultrasonography in the Differentiation of Endometriomas from Hemorrhagic Ovarian Cysts: The Role of Texture Analysis.

J Pers Med 2021 Jun 28;11(7). Epub 2021 Jun 28.

Radiology and Imaging Department, County Emergency Hospital, Cluj-Napoca, Clinicilor Street, Number 5, 400006 Cluj-Napoca, Romania.

The ultrasonographic (US) features of endometriomas and hemorrhagic ovarian cysts (HOCs) are often overlapping. With the emergence of new computer-aided diagnosis techniques, this is the first study to investigate whether texture analysis (TA) could improve the discrimination between the two lesions in comparison with classic US evaluation. Fifty-six ovarian cysts (endometriomas, 30; HOCs, 26) were retrospectively included. Read More

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Occurrence of Zearalenone and Its Metabolites in the Blood of High-Yielding Dairy Cows at Selected Collection Sites in Various Disease States.

Toxins (Basel) 2021 06 28;13(7). Epub 2021 Jun 28.

Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.

Zearalenone (ZEN) and its metabolites, alpha-zearalenol (α-ZEL) and beta-zearalenol (-ZEL), are ubiquitous in plant materials used as feed components in dairy cattle diets. The aim of this study was to confirm the occurrence of ZEN and its selected metabolites in blood samples collected from different sites in the hepatic portal system (posthepatic-external jugular vein EJV; prehepatic-abdominal subcutaneous vein ASV and median caudal vein MCV) of dairy cows diagnosed with mastitis, ovarian cysts and pyometra. The presence of mycotoxins in the blood plasma was determined with the use of combined separation methods involving immunoaffinity columns, a liquid chromatography system and a mass spectrometry system. Read More

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Rupture of a mature cystic teratoma in a young girl caused by a car accident: an extremely rare case and review of the literature.

Folia Med (Plovdiv) 2021 Jun;63(3):438-442

Laiko General Hospital, Athens, Greece.

Mature cystic teratomas (MCT) of the ovary or dermoid cysts are commonly encountered benign ovarian lesions accounting for  approximately 70% of benign tumors and originating from germ cells. A rare case of peritonitis in a 17-year-old female patient caused by traumatic rupture of an MCT of the right ovary is herein presented. A meticulous search of the literature has also been performed. Read More

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Fetal abdominal tumors and cysts.

Darrell L Cass

Transl Pediatr 2021 May;10(5):1530-1541

Cleveland Clinic, Cleveland, OH, USA.

This article reviews the contemporary diagnosis and management of the most common abdominal neoplasms and cystic lesions diagnosed in the fetus. Fetal tumors discussed include teratomas (sacrococcygeal, cervical or mediastinal), mesoblastic nephroma, nephroblastoma (Wilms' tumor), neuroblastoma, and hepatoblastoma. Fetal abdominal cystic lesions discussed include ovarian cyst, choledochal cyst, intestinal duplication cyst, mesenteric cyst, simple hepatic cyst, and meconium pseudocyst. Read More

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Metastatic breast tumors from extramammary malignancies: a case series.

Surg Case Rep 2021 Jun 29;7(1):154. Epub 2021 Jun 29.

Department of Breast Oncology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Background: Metastatic breast tumors from extramammary malignancies are quite rare. Characteristics of such tumors are unclear due to small number of reported cases. During 2012-2019, approximately 3,500 malignant breast tumors were diagnosed with needle biopsy at our hospital and we experienced three cases (0. Read More

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Diagnostic accuracy and inter-observer reliability of the O-RADS scoring system among staff radiologists in a North American academic clinical setting.

Abdom Radiol (NY) 2021 Jun 29. Epub 2021 Jun 29.

Department of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

Purpose: The objective of this study is to evaluate the diagnostic accuracy, interobserver variability, and common lexicon pitfalls of the ACR O-RADS scoring system among staff radiologists without prior experience to O-RADS.

Materials And Methods: After independent review of the ACR O-RADS publications and 30 training cases, three fellowship-trained, board-certified staff radiologists scored 50 pelvic ultrasound exams using the O-RADS system. The diagnostic accuracy and area under receiver operating characteristic were analyzed for each reader. Read More

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Probing the tumorigenic potential of genetic interactions reconstituted in murine fallopian tube organoids.

J Pathol 2021 Jun 29. Epub 2021 Jun 29.

Department of Molecular Carcinogenesis, Chiba Cancer Center Research Institute, Chiba, Japan.

Genetically engineered mice have been the gold standard in modeling tumor development. Recent studies have demonstrated that genetically engineered organoids can develop subcutaneous tumors in immunocompromised mice, at least for organs that prefer predominant driver mutations for tumorigenesis. To further substantiate this concept, the fallopian tube (FT), a major cell of origin of ovarian high-grade serous carcinoma (HGSC), which almost invariably carries TP53 mutations, was investigated for p53 inactivation-driven tumorigenesis. Read More

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Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma.

Mod Pathol 2021 Jun 25. Epub 2021 Jun 25.

Department of Obstetrics and Gynecology, Kindai University Faculty of Medicine, Osaka, Japan.

Recent studies have reported cancer-associated mutations in normal endometrium. Mutations in eutopic endometrium may lead to endometriosis and endometriosis-associated ovarian cancer. We investigated PIK3CA mutations (PIK3CAm) for three hotspots (E542K, E545K, H1047R) in eutopic endometrium in patients with ovarian cancer and endometriosis from formalin-fixed paraffin-embedded specimens by laser-capture microdissection and droplet digital PCR. Read More

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Recent updates on animal models for understanding the etiopathogenesis of polycystic ovarian syndrome.

Life Sci 2021 Sep 23;280:119753. Epub 2021 Jun 23.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Australia.

Polycystic ovarian syndrome (PCOS) is the primary cause of female infertility affecting several women worldwide. Changes in hormonal functions such as hyperandrogenism are considered a significant factor in developing PCOS in women. In addition, many molecular pathways are involved in the pathogenesis of PCOS in women. Read More

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September 2021

An Unusual Case of Right Flank Pain.

Am J Kidney Dis 2021 07;78(1):A12-A14

Venkateshwar Hospital, Dwarka, New Delhi, India.

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Active immunization against GnRH as an alternative therapeutic approach for the management of Bos indicus oocyte donors diagnosed with chronic cystic ovarian disease.

Theriogenology 2021 Jun 18;172:133-141. Epub 2021 Jun 18.

Universidade José do Rosário Vellano, Alfenas, MG, 37130-000, Brazil; Embrapa Gado de Leite, Juiz de Fora, MG, 36038-330, Brazil.

The aim of this study was to evaluate the effect of active immunization against GnRH in Nelore (Bos indicus) cows repeatedly used as oocyte donors that developed chronic cystic ovarian disease (COD). In the first experiment, ovarian and uterine features were first compared between COD cows (n = 15) and healthy cows (n = 22, cycling control group) from the same breed and herd. Cows with COD had a greater number of large (P < 0. Read More

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Large Ovarian Follicle Cyst: Benign Mimic of Cystic Adult Granulosa Cell Tumor.

Int J Gynecol Pathol 2021 Jun 23. Epub 2021 Jun 23.

Department of Pathology (E.R.M.M., T.H., S.L.S.) Rogel Cancer Center (S.L.S.), University of Michigan, Ann Arbor, Michigan.

While most ovarian follicle cysts are <8 cm in greatest dimension, much larger follicle cysts (up to 18.5 cm) have been reported. To our knowledge, the FOXL2 mutation status of such cases has not been documented in the literature. Read More

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Insulin-like growth factor (IGF) system and hormonal-metabolic profile in women with polycystic ovary syndrome.

Bratisl Lek Listy 2021 ;122(7):469-473

AIM of the study was to compare serum levels of IGF-1, IGF-2 and insulin‑like growth factor‑binding protein 3 (IGFBP-3) among non‑obese and obese PCOS women, and to assess their relationship to metabolic and hormonal parameters.    METHODS: The study included 64 women diagnosed with PCOS (age 28.9 ± 5 years); 30 of them with BMI > 27 and 34 with BMI lower than 27. Read More

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Total parietal peritonectomy in primary debulking surgery for advanced ovarian cancer.

Gynecol Oncol Rep 2021 Aug 11;37:100805. Epub 2021 Jun 11.

Department of Obstetrics and Gynecology, The Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minato-ku, Tokyo, Japan.

The object of this study is to evaluate the clinical safety and efficacy of total parietal peritonectomy (TPP) in primary debulking surgery (PDS) for advanced ovarian cancer. This retrospective single-center study analyzed 16 patients with FIGO stages IIIC-IVB epithelial ovarian cancer who underwent TPP in PDS and achieved macroscopically complete resection between April 2015 and June 2016. The median age of 16 patients was 52. Read More

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Characteristics of ovarian endometrioma during pregnancy.

J Obstet Gynaecol Res 2021 Jun 21. Epub 2021 Jun 21.

Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, Yokohama, Japan.

Aim: During pregnancy, the ovarian endometrioma generally decreases in size and occasionally ruptures. We evaluated (1) whether and how ovarian-endometrioma size changes from the first trimester to the postdelivery period, and (2) the type of endometrioma more likely to rupture during pregnancy.

Methods: During an 18-year period (2000-2018), ultrasound in the first trimester revealed ovarian endometrioma in 149 pregnant women at our tertiary institute. Read More

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A rare ovarian hilus cell tumour accompanying bilateral serous cystadenomas: report of a case.

J Ovarian Res 2021 Jun 21;14(1):81. Epub 2021 Jun 21.

Department of Pathology and Clinical Laboratory, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan.

Background: Hilus cell tumours is considered an uncommon branch of androgen producing neoplasms that accounts for < 5% of all ovarian tumours. They are mostly benign and have characteristic gross and microscopic features. Here we present the first case of a hilus cell tumour in association with bilateral serous cystadenomas. Read More

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Malignant transformation of ovarian teratoma responded well to immunotherapy after failed chemotherapy: a case report.

Ann Palliat Med 2021 Jun 21. Epub 2021 Jun 21.

Department of Oncology, Second Affiliated Hospital of Army Military Medical University, Chongqing, China.

Mature cystic teratomas (MCTs), also known as dermoid cysts, are the most common ovarian germ cell tumors and the most common ovarian neoplasms in patients younger than 20 years. MCTs mainly appear as pelvic masses that are made up of different types of well differentiated derivates of at least two germinative cell types. MCT of the ovary is always benign lesions with slow growth and good prognosis. Read More

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Pancreas in Hereditary Syndromes: Cross-sectional Imaging Spectrum.

Radiographics 2021 Jul-Aug;41(4):1082-1102. Epub 2021 Jun 18.

From the Departments of Radiology (V.S.K., S.B., H.R.) and Pathology (A.N.), University of Texas Health at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229; Department of Radiology, Le Bonheur Children's Hospital, Memphis, Tenn (J.N.S.); Department of Radiology, University of Texas M. D. Anderson Cancer Center, Houston, Tex (A.C.M., S.R.P.); Department of Radiology, University of Wisconsin, Madison, Wis (M.G.L.); Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pa (A.D.); and Department of Radiology, Mayo Clinic, Scottsdale, Ariz (C.O.M.).

A wide spectrum of hereditary syndromes predispose patients to distinct pancreatic abnormalities, including cystic lesions, recurrent pancreatitis, ductal adenocarcinoma, nonductal neoplasms, and parenchymal iron deposition. While pancreatic exocrine insufficiency and recurrent pancreatitis are common manifestations in cystic fibrosis and hereditary pancreatitis, pancreatic cysts are seen in von Hippel-Lindau disease, cystic fibrosis, autosomal dominant polycystic kidney disease, and McCune-Albright syndrome. Ductal adenocarcinoma can be seen in many syndromes, including Peutz-Jeghers syndrome, familial atypical multiple mole melanoma syndrome, Lynch syndrome, hereditary breast and ovarian cancer syndrome, Li-Fraumeni syndrome, and familial pancreatic cancer syndrome. Read More

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STING pathway expression in low-grade serous carcinoma of the ovary: an unexpected therapeutic opportunity?

J Pathol Clin Res 2021 Jun 17. Epub 2021 Jun 17.

Department of Molecular Oncology, BC Cancer Research Center, Vancouver, BC, Canada.

Ovarian carcinoma histotypes are distinct diseases with variable clinical outcomes and response to treatment. There is a need for new subtype-specific treatment modalities, especially for women with widespread and chemo-resistant disease. Stimulator of interferon genes (STING) is a part of the cGAS-STING pathway that mediates innate immune defence against infectious DNA-containing pathogens and also detects tumour-derived DNA and generates intrinsic antitumour immunity. Read More

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Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome.

Prague Med Rep 2021 ;122(2):73-79

Institute of Endocrinology, Prague, Czech Republic.

The hypothesis that the most common female endocrine disease, the polycystic ovarian syndrome (PCOS), has a male equivalent, has recently become more widely accepted. The male form of PCOS is marked by alterations in the secretion of gonadotropins, increased insulin resistance, and changes of the levels of several steroid hormones, with clinical manifestations including premature androgenic alopecia (AGA). Because these symptoms are not always found in men with genetic predispositions, knowledge of the male equivalent of PCOS needs to be supplemented by measurements of adrenal 11-oxygenated C19 steroids, particularly 11-keto-, and 11β-hydroxy-derivatives of testosterone and dihydrotestosterone, by focusing on the newly-realized role of skin as an endocrine organ, and by confirming any age-related factors in glucose metabolism disorders in such predisposed men. Read More

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Effects of atorvastatin on the insulin resistance in women of polycystic ovary syndrome: A systematic review and meta-analysis.

Medicine (Baltimore) 2021 Jun;100(24):e26289

Department of Gynecology, Tongde Hospital of Zhejiang Province, Hangzhou, China.

Background: Atorvastatin treatment has been suggested as a therapeutic method for women with polycystic ovary syndrome (PCOS) in many clinical studies. Nonetheless, the effects of atorvastatin on insulin resistance in PCOS patients still remain controversial.

Objective: The aim of this report was to evaluate the effects of atorvastatin therapy on the insulin resistance in the treatment of PCOS compared to that of placebo, in order to confer a reference for clinical practice. Read More

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Transumbilical laparoendoscopic single-site surgery with a self-made port to remove giant ovarian cysts.

Asian J Surg 2021 Aug 12;44(8):1091-1093. Epub 2021 Jun 12.

Department of Gynecologic Oncology, Qinghai University Affiliated Hospital, Xining, 810001, Qinghai province, China.

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Hydatid cyst of the ovary - a very rare type of cystic ovarian lesion: A case report.

Case Rep Womens Health 2021 Jul 28;31:e00330. Epub 2021 May 28.

Department of Surgery, College of Medicine, University of Duhok, Kurdistan Region, Iraq.

Background: Hydatid disease is a zoonotic condition caused by the adult or the larval stages of tapeworms belonging to the species or less commonly . The presentation depends on the site of involvement. Many cases are not symptomatic and may be discovered accidentally. Read More

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Association of Angiotensin-Converting Enzyme gene polymorphism in Pakistani women with the atypical steroidogenesis in Polycystic ovarian syndrome: A case-control study.

Saudi J Biol Sci 2021 Jun 14;28(6):3483-3489. Epub 2021 Mar 14.

Department of Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan.

Background: Polymorphism in the angiotensin-converting enzyme gene (ACE) is responsible for elevated ACE concentrations in plasma. High ACE levels induce insulin resistance and hyperandrogenism, which are the main attributes of polycystic ovary syndrome (PCOS). Therefore, it was hypothesized that I/D polymorphism plays a role in the pathogenesis of PCOS. Read More

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Early Predictors of Gestational Diabetes Mellitus in IVF-Conceived Pregnancies.

Endocr Pract 2021 Jun 17;27(6):579-585. Epub 2020 Dec 17.

Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Clinical Sciences Research Laboratories, University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, United Kingdom.

Objective: Gestational diabetes mellitus (GDM) is associated with adverse maternal and fetal outcomes. This study aimed to identify early and reliable GDM predictors that would enable implementation of preventive and management measures.

Methods: The participants were a 28-week prospective cohort of in vitro fertilization (IVF)-conceived pregnant women (≤39 years, body mass index [BMI] 18. Read More

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The therapeutic effects of glucagon-like peptide-1 receptor agonists and metformin on polycystic ovary syndrome: A protocol for systematic review and meta-analysis.

Medicine (Baltimore) 2021 Jun;100(23):e26295

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Background: Obesity and insulin resistance (IR) are common in polycystic ovary syndrome (PCOS), which contribute to reproductive and metabolic abnormalities. Metformin increases insulin sensitivity, but it is associated with unsatisfied benefits of weight loss. Recent studies have reported that glucagon-like peptide 1 (GLP-1) receptor agonists improve IR and reduce weight in women with PCOS. Read More

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The expression of platelet-derived growth factor, epidermal growth factor, and insulin-like growth factor-II in patients with polycystic ovary syndrome and its correlation with pregnancy outcomes.

Ann Palliat Med 2021 May;10(5):5671-5678

Department of Gynecology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.

Background: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder with complex pathogenesis. This study aimed to analyze the expression of platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and insulin-like growth factor-II (IGF-II) in patients with PCOS and its correlation with pregnancy outcomes.

Methods: A total of 104 PCOS patients admitted to the Cangzhou Central Hospital from January 2015 to February 2018 were selected as the PCOS group, and 92 healthy pregnant women who received health examinations in the hospital during the same period were selected as the control group. Read More

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Kymographic characteristics of voice in women with Polycystic ovary syndrome.

Codas 2021 4;33(5):e20200128. Epub 2021 Jun 4.

Department of Audiology and Speech Language Pathology, Kasturba Medical College, Mangalore (Karnataka), India; Manipal Academy of Higher Education - Manipal (Karnataka), India.

Purpose: Polycystic ovary syndrome (PCOS) is heterogenous condition with commonly associated symptoms include irregular menstrual cycle, hirsutism, baldness, adult acne, and weight gain There have been few attempts at profiling the voice characteristics of women with polycystic ovary syndrome. Videokymography enables to detect even subtle variationsin vocal fold vibrations. The aim of the present study was to study the videokymographic characteristics among women with PCOS. Read More

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