294,302 results match your criteria orthopaedic surgery

Breakage of sliding hip screw after fixation of pertrochanteric hip fracture: A rare complication.

Int J Surg Case Rep 2021 Jul 22;85:106226. Epub 2021 Jul 22.

Division of Orthopedic Surgery, Lebanese University, Faculty of Medical Sciences, Beirut, Lebanon.

Introduction: The authors report a rare case of lag screw breakage in a patient treated using locking DHS with home-made trochanteric stabilizing plate (TSP) for pertrochanteric hip fracture.

Case Presentation: A 67 year-old female was operated for pertrochanteric hip fracture with incompetent lateral wall using locking DHS with home-made TSP. At seven months postoperative, there was radiographic nonunion with breakage of the sliding lag screw. Read More

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Diabetes Mellitus does not Impact Achievement of a Minimum Clinically Important Difference following Anterior Cervical Discectomy and Fusion.

World Neurosurg 2021 Jul 23. Epub 2021 Jul 23.

Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612. Electronic address:

Background: Diabetes mellitus (DM) has been identified as a risk factor for poorer outcomes following anterior cervical discectomy and fusion (ACDF). This study aims to evaluate the impact DM has on achievement of MCID (minimum clinically important difference) following ACDF.

Methods: A surgical database was reviewed for patients who underwent primary, single level ACDF procedures with posterior instrumentation. Read More

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Synergy between vitamin E and D-sorbitol in enhancing oxidation stability of highly crosslinked ultrahigh molecular weight polyethylene.

Acta Biomater 2021 Jul 23. Epub 2021 Jul 23.

College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, 610065 Chengdu, China. Electronic address:

Oxidative stability of radiation crosslinked ultrahigh molecular weight polyethylene (UHMWPE) artificial joints is significantly improved by vitamin E (VE), but there is a dilemma that VE hinders crosslinking and thus jeopardizes the wear of UHMWPE. In this effort, we proposed an efficient strategy to stabilize UHMWPE under limited antioxidant contents, where VE and D-sorbitol (DS) were used as the primary antioxidant and the secondary antioxidant respectively. For non-irradiated blends with fixed antioxidant contents, oxidative stability accessed by oxidation induction time (OIT) of VE/DS/UHMWPE blends was superior to that of VE/UHMWPE blends, while DS/UHMWPE blends showed no increase in OIT. Read More

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3-Dimensional Footprint Mapping of the Deltoid and Trapezius: Anatomic Pearls for Acromioclavicular Joint Reconstruction.

Arthroscopy 2021 Jul 23. Epub 2021 Jul 23.

Department of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, USA.

Purpose: The purpose of this study was to perform a quantitative anatomic evaluation of the deltoid and trapezius footprints in relation to the lateral clavicle and acromioclavicular (AC) joint capsule to assist in surgical technique of AC joint reconstructions.

Methods: Fourteen fresh-frozen human cadaveric shoulders from 9 donors were analyzed. Meticulous dissection of the deltoid origin and trapezius insertions to the clavicle and acromioclavicular (AC) joint was performed. Read More

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Arthroscopically assisted coraco-clavicular ligament reconstruction in treatment of acute displaced distal clavicle fractures provides good to excellent shoulder function despite low union rates and high complication rates. A systematic review.

Arthroscopy 2021 Jul 23. Epub 2021 Jul 23.

Consultant Shoulder & Elbow Surgeon, University Hospitals Birmingham NHS Foundation Trust, UK.

Purpose: The aim of this systematic review was to assess the clinical outcome of arthroscopically assisted coraco-clavicular ligament (AACCL) reconstruction for treatment of displaced distal clavicle fractures in terms of union rate, complications and shoulder function.

Methods: A review of the online databases MEDLINE and Embase was conducted on 1 January 2021 according to PRISMA guidelines. The review was registered prospectively in the PROSPERO database. Read More

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Ultrasonography Outperforms Magnetic Resonance Imaging in Diagnosing Partial Thickness Subscapularis Tear.

Arthroscopy 2021 Jul 23. Epub 2021 Jul 23.

Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, China. Electronic address:

Purpose: To evaluate the diagnostic reliability of ultrasonography (US) and magnetic resonance imaging (MRI) for subscapularis (SSC) tears with shoulder arthroscopy as the gold standard, and to investigate the diagnostic value of two MRI signs (lesser tuberosity cysts and subcoracoid cysts) for SSC tears.

Methods: We consecutively enrolled 437 patients who were scheduled to undergo arthroscopic rotator cuff repair from January 2019 to December 2020. Patients with previous shoulder surgery or shoulder fracture, recurrent shoulder instability and systemic inflammatory disease were excluded. Read More

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Orthop Surg 2021 Jul;13(5):1694

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Prosthesis rejection in individuals with limb amputation: a narrative review with respect to rehabilitation.

Riv Psichiatr 2021 Jul-Aug;56(4):175-181

School of Medicine and Surgery, University of Milano Bicocca, Italy.

Objective: To evaluate the refusal of the prosthesis in order to highlight elements in determining the acceptance/rejection of the prosthetic devices, and its role on rehabilitation program.

Methods: A literature review through a search of the database Medline for studies published between October 2007 and May 2020 using the key words "prosthesis", "limb", and "accept"*.

Results: Nine studies were included. Read More

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Examination of Adult Spinal Deformity Patients Undergoing Surgery with Implanted Spinal Cord Stimulators and Intrathecal Pumps.

Spine (Phila Pa 1976) 2021 Jul 23. Epub 2021 Jul 23.

Department of Orthopaedics, Warren Alpert Medical School, Brown University, Providence, RI Warren Alpert Medical School, Brown University, Providence, RI Brown University, Providence, RI Hospital for Special Surgery, New York, NY University of Pittsburgh Medical Center, Pittsburgh, PA Department of Orthopedics, NYU Langone Orthopedic Hospital, New York, NY University of Virginia Health System, Charlottesville, VA Duke University, Durham, NC Washington University, St. Louis, MO University of California-Davis, Sacramento, CA Norton Leatherman Spine Center, Louisville, KY Scripp's Clinic, La Jolla, CA Johns Hopkins University, Baltimore, MD University of Calgary Spine Program, University of Calgary, Alberta Department of Orthopaedic Surgery, Baylor Scoliosis Center, Dallas, TX University of Kansas Hospital, Kansas City, KS Denver International Spine Center, Denver, CO University of California-San Francisco, CA Swedish Neuroscience Institute, Seattle, WA.

Study Design: Retrospective cohort study of a prospectively collected multi-center database of adult spinal deformity (ASD) patients.

Objective: We hypothesized that patients undergoing ASD surgery with and without previous SCS/ITP would exhibit increased complication rates but comparable improvement in HRQOL.

Summary Of Background Data: ASD patients sometimes seek pain management with spinal cord stimulators (SCS) or intrathecal medication pumps (ITP) prior to spinal deformity correction. Read More

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Mapping of Venous Sinus Anatomy and Occipital Bone Thickness for Safe Screw Placement in 100 patients with 46,200 Standardized Measurements Using Computed Tomography Angiography.

Spine (Phila Pa 1976) 2021 Jul 23. Epub 2021 Jul 23.

Department of Orthopedic Surgery, Spine Service, Hospital for Special Surgery, New York NY, Unites States of America Weill Cornell Medical College, New York NY, Unites States of America Department of Orthopedic and Trauma Surgery, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Germany Department for Radiology, Hospital for Special Surgery, New York NY, Unites States of America Department of Orthopedic and Trauma Surgery, Medical University of Berlin, Charitéplatz 1, Berlin, 10117, Germany.

Study Design: Retrospective descriptive study.

Objective: To create topographical maps of occipital bone thickness and venous sinus (VS) presence to assess the risks of screw insertion in four commercially available occipital plates.

Summary Of Background Data: Craniocervical junction instability and deformity are serious pathological conditions that require posterior fixation of the occipital bone to the cervical vertebrae. Read More

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Efficacy of Hematoma Aspiration and Platelet-rich Plasma Muscle Injections for the Treatment of Hamstring Strains in Athletes.

Med Sci Sports Exerc 2021 Jul 23. Epub 2021 Jul 23.

Division of Musculoskeletal Imaging and Interventions, Department of Radiology Divison of Sports Medicine, Department of Orthopedic Surgery, Thomas Jefferson University Hospital, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.

Introduction: The effect of platelet-rich plasma (PRP) treatment on recovery in acute hamstring injuries is controversial. Previous study results are inconsistent, and a standardized therapeutic approach has not been established yet.

Purpose: To assess the treatment effect using a combination of hematoma aspiration and muscle strain PRP injection in partial hamstring muscle tears (grade 2 strains) in athletes. Read More

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Head Impact Exposure of a Youth Football Team over Eight Consecutive Seasons.

Med Sci Sports Exerc 2021 Jul 23. Epub 2021 Jul 23.

Sanford Sports Science Institute, Sanford Sports, Sanford Health, Sioux Falls, SD Sanford Orthopedics and Sports Medicine Research, Sanford Health, Sioux Falls, SD Environmental Influences on Health and Disease Group, Sanford Research, Sioux Falls, SD.

Despite growing evidence for the potential risk of brain injury due to repetitive, subconcussive head impacts in youth football, a longitudinal assessment of head impact exposure (HIE) in this population is lacking.

Purpose: This study examined HIE of middle school football players over multiple seasons.

Methods: HIE was evaluated in 103 football players (11-14 yr) who participated in a community-based youth tackle football program, up to two years, with the same coaching staff over eight consecutive seasons (2012-2019). Read More

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Skeletal Maturity Using Knee X-rays: Understanding the Resilience of 7 Radiographic Parameters to Rotational Position.

J Pediatr Orthop 2021 Jul 26. Epub 2021 Jul 26.

Department of Orthopaedic Surgery, Rainbow Babies and Children's Hospital at Case Western Reserve University School of Medicine Center for Clinical Research, University Hospitals Cleveland Medical Center, Cleveland, OH.

Background: Recently, a skeletal maturity system using knee radiographs, named the modified Roche-Wainer-Thissen (RWT) system, has been developed using 7 discrete radiographic parameters. While the system has been shown to significantly outperform the Greulich and Pyle atlas, the effect of rotational variation of the knee radiograph on skeletal maturity determinations has not been studied.

Methods: Normal knee computed tomography scans of 12 male children ages 10 to 16 years and 8 female children ages 8 to 14 years were obtained retrospectively, converted into 3-dimensional reconstructions, and then used to simulate knee radiographs in 5 different rotational positions. Read More

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Is it time to revisit the Minimum Information for Studies Evaluating Biologics in Orthopaedics (MIBO) Guidelines: Platelet-Rich Plasma and Mesenchymal Stem Cells.

Am J Phys Med Rehabil 2021 Jul 23. Epub 2021 Jul 23.

Assistant Professor, Department of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, OH. Assistant Professor, Department of Orthopedic Surgery, The Ohio State University, Columbus, OH. Professor, Department of Orthopedic Surgery, The Ohio State University, Columbus, OH. Assistant Professor, Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH.

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Am J Phys Med Rehabil 2021 Jul 23. Epub 2021 Jul 23.

Shirley Ryan AbilityLab, Chicago, IL Department of Physical Medicine and Rehabilitation, Northwestern Feinberg School of Medicine, Chicago, IL University of Michigan Medical School, Ann Arbor, MI University of Illinois-Chicago Medical School, Chicago IL Department of Orthopaedic Surgery, University of Missouri.

Objective: Compare the acute effects of walking the golf course versus using a golf cart during a round of golf on biological markers of joint disease, joint pain, and cardiovascular parameters in individuals with knee osteoarthritis (OA).

Methods: Participants with knee OA (n = 10) above the age of 50 were recruited for this crossover designed study in which they completed two 18-hole rounds of golf; 1) walking the course 2) using a golf cart (GC). Five control participants (n = 5) performed the walking condition only. Read More

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The role of acetic acid in orthopaedic surgery.

J Perioper Pract 2021 Jul 26:17504589211015629. Epub 2021 Jul 26.

Department of Trauma and Orthopaedics, Addenbrookes Major Trauma Unit, Cambridge University Hospitals, Cambridge, UK.

Acetic acid has become more commonly used in orthopaedic surgery. The purposed roles include biofilm eradication and surgical debridement, postoperative scar reduction and managing soft tissue injuries. Current research is scarce and does not provide conclusive evidence behind acetic acid's efficacy in orthopaedic procedures such as biofilm eradication or acetic acid iontophoresis in soft tissue injuries. Read More

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Risks vs. benefits of switching therapy in patients with postmenopausal osteoporosis.

Expert Rev Endocrinol Metab 2021 Jul 26:1-12. Epub 2021 Jul 26.

Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo, Japan.

: Osteoporosis is characterized by the fragility of bones, leading to fractures and, consequently, the deterioration of functional capacity and quality of life. Postmenopausal women, in particular, are prone to osteoporosis and often require anti-osteoporosis treatment. In the last few decades, various anti-osteoporosis drugs have been approved for clinical use. Read More

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A Bibliometric Analysis of the Top-Cited Articles on Diabetic Foot Ulcers.

Int J Low Extrem Wounds 2021 Jul 26:15347346211034388. Epub 2021 Jul 26.

Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

The aim of this study was to determine the top-cited articles in the field of diabetic foot ulcer (DFU) research. A cross-sectional bibliometric analysis was conducted in January 2021 by using Boolean search terms in the Scopus and the Web of Science databases. The 50 top-cited articles that met the inclusion criteria were ranked and evaluated for several characteristics, including year of publication, country of origin, authorship, publishing journal, topic categories, publishing type, and level of evidence. Read More

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Prediction of Shoulder Stiffness After Arthroscopic Rotator Cuff Repair.

Am J Sports Med 2021 Jul 26:3635465211028980. Epub 2021 Jul 26.

Shoulder and Elbow Surgery, Schulthess Clinic, Zurich, Switzerland.

Background: Postoperative shoulder stiffness (POSS) is a prevalent adverse event after arthroscopic rotator cuff repair (ARCR) that is associated with major limitations in everyday activities and prolonged rehabilitation.

Purpose/hypothesis: The purpose was to develop a predictive model for determining the risk of POSS within 6 months after primary ARCR. We hypothesized that sufficient discrimination ability of such a model could be achieved using a local institutional database. Read More

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Return to Baseline Physical Activity After Bone-Patellar Tendon-Bone Versus Hamstring Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Am J Sports Med 2021 Jul 26:3635465211017522. Epub 2021 Jul 26.

Centre Hospitalier Affilié Universitaire de Québec - Pavillon Enfant-Jésus, Université Laval, Québec, Canada.

Background: Bone-patellar tendon-bone (BPTB) and hamstring tendon (HT) autografts are the most utilized grafts for primary anterior cruciate ligament (ACL) reconstruction. The ability of a patient to return to a preinjury level of physical activity is a key consideration in choice of graft; the influence of graft choice on this metric lacks consensus in the literature.

Purpose: To assess the effects of autograft choice (BPTB vs HT) for primary ACL reconstruction on return to baseline level of physical activity and/or sports participation. Read More

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Injection-Free Delivery of MSC-Derived Extracellular Vesicles for Myocardial Infarction Therapeutics.

Adv Healthc Mater 2021 Jul 26:e2100312. Epub 2021 Jul 26.

Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China.

As emerging therapeutic factors, extracellular vesicles (EVs) offer significant potential for myocardial infarction (MI) treatment. Current delivery approaches for EVs involve either intra-myocardial or intravenous injection, where both have inherent limitations for downstream clinical applications such as secondary tissue injury and low delivery efficiency. Herein, an injection-free approach for delivering EVs onto the heart surface to treat MI is proposed. Read More

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Overexpression of HIF-1α enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis.

Environ Toxicol 2021 Jul 26. Epub 2021 Jul 26.

Department of Orthopaedics of the First Affiliated Hospital, Medical School, Xi'an Jiaotong University, Xi'an, China.

Glucocorticoid (GC; dexamethasone, DEX) -induced osteonecrosis of the femoral head (GIOFH) is a challenging orthopedic disease, and its underlying mechanism remains not clear. This study exposed murine long bone osteocyte-Y4 (MLO-Y4) cells to DEX below normoxic or hypoxic circumstances and found that cell autophagy have been reduced. At the same time, flow cytometry analysis showed increased apoptosis, which was more pronounced in hypoxic environments. Read More

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Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration.

J Vis Exp 2021 Jul 8(173). Epub 2021 Jul 8.

Laboratory of Cell Biology, Department of Orthopedic Surgery, University Hospital of Tübingen.

Intervertebral disc (IVD) degeneration is a leading cause of low back pain and it entails a high degree of impairment for the affected individuals. To decode disc degeneration and to be able to develop regenerative approaches a thorough understanding of the cellular biology of the IVD is essential. One aspect of this biology that still remains unanswered is the question of how cells are spatially arranged in a physiological state and during degeneration. Read More

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Intervertebral Disc Degeneration Models for Pathophysiology and Regenerative Therapy -Benefits and Limitations.

J Invest Surg 2021 Jul 26:1-18. Epub 2021 Jul 26.

The Second Clinical Medical College, Lanzhou University, Lanzhou, P.R. China.

This review summarized the recent intervertebral disc degeneration (IDD) models and described their advantages and potential disadvantages, aiming to provide an overview for the current condition of IDD model establishment and new ideas for new strategies development of the treatment and prevention of IDD.The database of PubMed was searched up to May 2021 with the following search terms: nucleus pulposus, annulus fibrosus, cartilage endplate, intervertebral disc(IVD), intervertebral disc degeneration, animal model, organ culture, bioreactor, inflammatory reaction, mechanical stress, pathophysiology, epidemiology. Any IDD model-related articles were collected and summarized. Read More

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Development of a 3D Bioartificial Shoulder Joint Implant Mimetic of Periprosthetic Joint Infection.

Tissue Eng Part A 2021 Jul 26. Epub 2021 Jul 26.

University of Western Ontario, 6221, Department of Biochemistry, London, Ontario, Canada.

Post-surgical infections of the shoulder joint involving are difficult to diagnose and manage. Despite the devastating clinical complications and costly healthcare burden of joint infections, the scarcity of joint infection models was identified as an unmet need by the 2019 International Consensus on Orthopedic Infections. In this study, we have developed a novel 3D shoulder joint implant mimetic (S-JIM) that includes a surgical metal surface and supports a co-culture of and patient-derived shoulder capsule fibroblasts. Read More

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Endochondral Bone Tissue Engineering Using Human Induced Pluripotent Stem Cells.

Tissue Eng Part A 2021 Jul 26. Epub 2021 Jul 26.

Kobe University Graduate School of Medicine, Department of Orthopaedic Surgery, Kobe, Japan;

There has been great interest in the use of induced pluripotent stem cells (iPSCs) in bone regenerative strategies for bone defects. In the present study, we investigated whether the implantation of chondrogenically differentiated iPSC-derived mesenchymal stem cells (iMSCs) could lead to the successful regeneration of bone defects in nude mice. Two clones of human iPSCs (201B7 and 454E2) were used. Read More

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Iodine Immobilized Metal-Organic Framework for NIR-Triggered Antibacterial Therapy on Orthopedic Implants.

Small 2021 Jul 26:e2102315. Epub 2021 Jul 26.

Orthopedics Research Institute of Zhejiang University, Department of Orthopedic Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, P. R. China.

Iodine has been known as an effective disinfectant with broad-spectrum antimicrobial potency yet without drug resistance risk when used in clinic. However, the exploration of iodine for antibacterial therapy in orthopedics remains sparse due to its volatile nature and poor solubility. Herein, leveraging the superior absorption capability of metal-organic frameworks (MOFs) and their inherent photocatalytic properties, iodine-loaded MOF surface is presented to realize responsive iodine release along with intracellular reactive oxygen species(ROS) oxidation under near-infrared (NIR) exposure to achieve synergistic antibacterial effect. Read More

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Current research progress in targeted anti-angiogenesis therapy for osteosarcoma.

Cell Prolif 2021 Jul 26:e13102. Epub 2021 Jul 26.

Division of Regenerative Biology, School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.

Osteosarcoma (OS) is the most common primary malignant bone tumour with a peak in incidence during adolescence. Delayed patient presentation and diagnosis is common with approximately 15% of OS patients presenting with metastatic disease at initial diagnosis. With the introduction of neoadjuvant chemotherapy in the 1970s, disease prognosis improved from 17% to 60%-70% 5-year survival, but outcomes have not significantly improved since then. Read More

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