1,232 results match your criteria orbital apex


Orbital Apex Syndrome due to Orbital Mucormycosis after Teeth Infection: A Successful Case Report.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):110-115. Epub 2021 Apr 8.

Ophthalmology Department, Centro Hospitalar e Universitário São João, Porto, Portugal.

Rhino-orbital-cerebral mucormycosis is a severe and rapidly progressive fungal infection associated with low survival rates. Early diagnosis and proper management are mandatory. We report the case of a 20-year-old female with diabetic ketoacidosis and teeth infection, who presented with sudden orbital apex syndrome. Read More

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Next-Generation Sequencing-Based Decision Support for Intensivists in Difficult-to-Diagnose Disease States: A Case Report of Invasive Cerebral Aspergillosis.

A A Pract 2021 May 6;15(5):e01447. Epub 2021 May 6.

From the Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

Aspergillus spp. are widespread environmental pathogens that can induce invasive aspergillosis, especially in immunocompromised patients. An 86-year-old female patient presented with a rare case of invasive cerebral aspergillosis. Read More

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Optic Canal Decompression: Concepts and Techniques: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 Apr 30. Epub 2021 Apr 30.

Department of Neurological Surgery, Mayo Clinic, Phoenix, Arizona, USA.

The optic canal (OC) is a bony channel that transmits the optic nerve (ON) and ophthalmic artery (OphA) as they course through the lesser wing of the sphenoid bone to the orbital apex. The OC is involved in a variety of intracranial and extracranial pathologies,1 and opening of the canal may be necessary in order to achieve adequate exposure, better disease control, and vision preservation.2 Depending on the location of the pathology and its relationship with the optic nerve, the OC may be decompressed through an open transcranial approach or an endoscopic endonasal approach. Read More

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Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy.

Eye Vis (Lond) 2021 Apr 28;8(1):19. Epub 2021 Apr 28.

The Eye Hospital of Wenzhou Medical University, No. 270 Xueyuan Xi Road, Wenzhou, Zhejiang, 325027, P. R. China.

Background: To describe the surgical technique and assess the clinical efficacy and safety of modified endoscopic transnasal orbital apex decompression in the treatment of dysthyroid optic neuropathy.

Methods: In this retrospective research, forty-two subjects (74 orbits) who underwent modified endoscopic transnasal orbital apex decompression for the treatment of dysthyroid optic neuropathy were enrolled. Preoperative and postoperative best-corrected visual acuity (BCVA), visual field mean deviation (MD), Hertel exophthalmometry, and new onset diplopia were assessed before and after the intervention. Read More

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COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?

BMJ Case Rep 2021 Apr 27;14(4). Epub 2021 Apr 27.

General Medicine, Nitte University K S Hegde Medical Academy, Mangalore, Karnataka, India.

A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. Read More

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Title of the Article: Paranasal Mucormycosis in COVID-19 Patient.

Indian J Otolaryngol Head Neck Surg 2021 Apr 22:1-4. Epub 2021 Apr 22.

Department of Otorhinolaryngology and Head and Neck Surgery, K.S.Hegde Medical Academy, NITTE University, Mangalore, Karnataka 575018 India.

There have been a variety of complications reported during and post- COVID infection. Recently, there has been an increase in sporadic cases of paranasal sinus mucormycosis in COVID- 19 patients. We report a case of COVID- 19 patient diagnosed to have orbital apex syndrome secondary to mucormycosis of nose and paranasal sinus requiring emergency endoscopic sinus surgery. Read More

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[Excisional surgery of orbital tumors].

Ophthalmologe 2021 Apr 23. Epub 2021 Apr 23.

Klinik für Augenheilkunde, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck, Deutschland.

The indications for orbital tumor surgery are an incisional biopsy to confirm the diagnosis or in malignant operable tumors a complete excision or a debulking to avoid complications in large invasively infiltrating tumors. In the case of benign tumors, the indications for surgery depend mostly on the clinical symptoms and cosmetic esthetic disfigurement. In the present article the preoperative examinations as well as surgical access approaches to different orbital regions, endoscopic procedures and methods of intraoperative navigation are presented. Read More

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Severe Cocaine-Induced Midline Destructive Lesions (CIMDL) Leading to Orbital Apex Syndrome and Peripheral Ulcerative Keratitis.

Ocul Immunol Inflamm 2021 Apr 19:1-4. Epub 2021 Apr 19.

Department of Ophthalmology, Hospital Universitari Doctor Peset, Valencia, Spain.

: To describe a case of cocaine-induced midline destructive lesions (CIMDL) associated with ocular autoimmune disease.: Observational case report.: A 45-year-old man with history of chronic osteolytic sinusitis due to cocaine abuse presented with sudden vision loss in right eye. Read More

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Case Report: Idiopathic Sclerosing Orbital Inflammation.

Optom Vis Sci 2021 Apr;98(4):409-417

Eye Institute, Medical College of Wisconsin, Milwaukee, Wisconsin.

Significance: Idiopathic sclerosing orbital inflammation (ISOI) is characterized by insidious, chronic, progressive inflammation and fibrosis that damage ocular structures and produce a mass effect. This case highlights the challenges in diagnosis and management of ISOI, as well as the associated ocular morbidities, including potential vision loss.

Purpose: The purpose of this study was to provide education regarding a rare condition that exhibits variable presentation and has an unpredictable success rate with regard to treatment paradigm. Read More

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Corticosteroid Therapy in Optic Neuropathy Secondary to Nasopharyngeal Carcinoma.

Cureus 2021 Mar 6;13(3):e13735. Epub 2021 Mar 6.

Department of Ophthalmology and Visual Sciences, School of Medicine Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, MYS.

Introduction: Nasopharyngeal carcinoma (NPC) is a tumor arising from the epithelial cells of the nasopharynx. NPC can spread and invade the base of skull, nasal cavity, paranasal sinuses, pterygopalatine fossa, and apex of the orbit. However, the involvement of the optic nerve in NPC is rare. Read More

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Pediatric subperiosteal orbital abscess characterization and prediction of size, location, and management.

Int J Pediatr Otorhinolaryngol 2021 May 28;144:110693. Epub 2021 Mar 28.

Division of Pediatric Otolaryngology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Introduction: Subperiosteal orbital abscess (SPOA) is a serious suppurative complication of pediatric sinusitis. The objective of this study is to stratify patient selection into those best treated medically versus surgically based on clinical outcomes.

Methods: This is a retrospective review of patients diagnosed with SPOA complicating sinusitis treated at a tertiary care pediatric hospital from 2002 through 2016. Read More

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One case of orbital apex syndrome caused by small cell lung cancer metastasis.

Rev Neurol (Paris) 2021 Mar 30. Epub 2021 Mar 30.

Department of Internal Medicine, the Third People's Hospital of Suining, Suining 629099, China. Electronic address:

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Ophthalmic Presentation and Outcomes for Malignant Sinonasal Tumors.

Ophthalmic Plast Reconstr Surg 2021 Mar 24. Epub 2021 Mar 24.

Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.

Purpose: To evaluate the ophthalmic clinical features and functional outcomes for patients with malignant sinonasal tumors who initially presented with orbital symptoms.

Patients And Methods: Retrospective chart review for patients seen at Moorfields Eye Hospital between 1997 and 2020. Patient demographics and clinical features, radiology, histology, and treatment outcomes were reviewed. Read More

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Orbital apex syndrome in COVID-19 patient, a case report.

Vis J Emerg Med 2021 Apr 22;23:101006. Epub 2021 Mar 22.

Department of Ophthalmology, Nikookari Eye Center, Tabriz University of Medical Sciences, Tabriz, Iran.

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A Meta-Analysis of Traumatic Orbital Apex Syndrome and the Effectiveness of Surgical and Clinical Treatments.

J Craniofac Surg 2021 Mar 22. Epub 2021 Mar 22.

Division of Plastic Surgery, Albany Medical Center, Albany Division of Plastic and Reconstructive Surgery, Montefiore Medical Center, Bronx, NY.

Purpose: Traumatic orbital apex syndrome (TOAS) commonly occurs secondary to trauma and irreversible ischemic optic neuropathy occurs as early as 2 hours after injury. Multiple treatment options have been described, however, there is a lack of consensus regarding the optimal treatment of these patients.

Methods: A systematic review of the PubMed Database from 1970 to 2020 was conducted, using the search terms "orbital apex," "syndrome," and "traumatic" with the Boolean operators "AND" or "OR. Read More

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Primary thymic atypical carcinoid with rare multiple bone metastasis: A case report and literature review.

Mol Clin Oncol 2021 Apr 25;14(4):78. Epub 2021 Feb 25.

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.

Primary thymic atypical carcinoid (TAC) is a type of extremely rare neuroendocrine tumor. Approximately one-third of patients with TAC tumors are asymptomatic, and no treatments of TAC have been rigorously tested in multicenter clinical trials. To date, there has been no previous case report of TACs with multiple skull metastases. Read More

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A rare case of orbital myositis.

J Ayub Med Coll Abbottabad 2020 Oct-Dec;32(Suppl 1)(4):S706-S708

Department of Radiology, Shifa International Hospital, Islamabad, Pakistan.

The orbital myositis is a rare inflammatory disorder of extraocular muscles and is considered a subtype of nonspecific orbital inflammatory syndrome. It is usually a unilateral disease process with a limited course. We report a case of a 34-year-old man who was referred to the Radiology Department at Shifa International Hospital, Islamabad with 6 months history of severe pain, swelling, and redness in the left eye associated with blurring of vision and headache. Read More

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An interesting case report of delayed presentation of visual loss from an Ethmoid Mucocoele. Should we offer emergency decompression?

Int J Surg Case Rep 2021 Apr 17;81:105744. Epub 2021 Mar 17.

Department of ENT, Luton & Dunstable University Hospital NHS Foundation Trust, Luton, UK.

Paranasal sinus mucocoeles commonly involve the frontoethmoidal sinuses and can rarely present with vision changes due to expansion and invasion through the orbit. A 50-year-old female presented out of hours with an acute, 16-h history of complete left sided visual loss, on a background of 3 days of visual changes. A left ethmoid mucocoele extending into the left orbital apex causing compression of the optic nerve was diagnosed on imaging. Read More

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Retrospective Case Analysis of Transnasal Endoscopic Resection of Benign Orbital Apex Tumors: Some Thoughts on Transnasal Endoscopic Surgery.

J Ophthalmol 2021 13;2021:6691203. Epub 2021 Feb 13.

Department of Orbital Diseases and Ocular Oncology, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.

Purpose: To deeply discuss the patient selection, surgical planning, surgical techniques, and the therapeutic challenge for endoscopic transnasal resection of benign orbital apex tumors (OATs).

Methods: We retrospectively analyzed the cases of 18 patients (18 eyes) with orbital apex cavernous hemangioma (OACH) who underwent endoscopic transnasal approach for resection of the tumor in Zhongshan Ophthalmic Center from March 2016 to May 2020. At each follow-up visit, the patients underwent measurement of their best-corrected visual acuity (BCVA), slit-lamp examination, indirect ophthalmoscopy, and visual field testing. Read More

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February 2021

Granulomatosis with Polyangiitis Presenting with Bilateral Orbital Apex Syndrome.

Case Rep Ophthalmol 2021 Jan-Apr;12(1):32-40. Epub 2021 Jan 7.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

We report a rare case of granulomatosis with polyangiitis (GPA) presenting with bilateral orbital apex syndrome (OAS). A 73-year-old woman with a history of endoscopic sinus surgery for ethmoidal sinusitis experienced a sudden decrease in visual acuity (VA) of both eyes. At the initial examination, her VA had decreased to 0. Read More

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January 2021

Orbital schwannoma with calcification treated by intracapsular excision: A case report.

Medicine (Baltimore) 2021 Feb;100(7):e24801

Department of Orbital Disease and Ocular Tumor, Hebei Eye Hospital, Xingtai, Hebei Province, China.

Rationale: Orbital schwannoma is a relatively rare orbital tumor, and calcification of the lesion is rarely found in the orbit. We report a case of orbital schwannoma which was characterized by calcification in the orbital muscle cone, and was cured by intracapsular excision.

Patient Concerns: A 54-year-old female with a complaint of a mass in the left orbit during a magnetic resonance imaging examination and symptom of dizziness 6 months before, presented with painless exophthalmos and vision decline in the left eye. Read More

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February 2021

Types of Transnasal Endoscopic Nasopharyngectomy for Recurrent Nasopharyngeal Carcinoma: Shanghai EENT Hospital Experience.

Front Oncol 2020 14;10:555862. Epub 2021 Jan 14.

Department of Otolaryngology, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China.

Background: Transnasal endoscopic nasopharyngectomy (TEN) has become increasingly used for recurrent nasopharyngeal carcinoma (rNPC); however, there is no report on the definitive resectable contour for TEN according to the latest staging system for nasopharyngeal carcinoma. The aim of this study was to establish the types of TEN for rNPC.

Materials And Methods: A total of 101 rNPC patients underwent TEN from January 2016 to April 2019 at the authors' institution. Read More

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January 2021

An impaired pupillary light reflex indices in Orbital Apex Syndrome - A rare case report.

J Fr Ophtalmol 2021 Feb 4. Epub 2021 Feb 4.

Department of Physiology & Biochemistry, Government Yoga and Naturopathy Medical College and Hospital, 600104 Chennai, Tamilnadu, India. Electronic address:

Background: The clinical presentation of reduced pupillary responses in orbital apex syndrome is currently not well understood clinically. The pupillary light reflex (PLR) is determined using dynamic pupillometry.

Case Details: A newly diagnosed 35-year-old diabetic female patient had ocular symptoms including orbital pain and ptosis, but no visual loss. Read More

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February 2021

Cavernous Sinus Thrombosis related to Orbital Cellulitis Serious Complication to Prevent: a case report and literature review.

Ann Med Surg (Lond) 2021 Feb 18;62:179-181. Epub 2021 Jan 18.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The authors report a case which aims to underline the importance of multidisciplinary management and rapid diagnosis of orbital cellulitis, for an adequate treatment of ocular damages and related complications, to prevent serious and permanent sequelae and avoid a fatal prognosis.

Presentation Of Case: A 61-year-old female reported to the oral and maxillofacial surgery department after she was dragged around for two months. She presented with a right facial swelling and orbital apex syndrome including proptosis, ophthalmoplegia and ptosis. Read More

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February 2021

Orbital Apex Syndrome: A Clinico-anatomical Diagnosis.

J Pediatr Neurosci 2020 Jul-Sep;15(3):336-337. Epub 2020 Nov 6.

Division of Child Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

An 8-month-old girl presented with fever, restricted left eye movements and increasing proptosis for 8 days. On examination she had left orbital cellulitis, relative afferent pupillary defect and ophthalmoplegia. Contrast-enhanced magnetic resonance imaging (MRI) brain with orbits revealed orbital apex syndrome (OAS) with cavernous sinus thrombosis. Read More

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November 2020

Sinonasal cancer encroaching the orbit: Ablation or preservation?

Oral Oncol 2021 03 28;114:105185. Epub 2021 Jan 28.

Section of Otorhinolaryngology - Head and Neck Surgery, Department of Neurosciences, University of Padua - "Azienda Ospedaliera di Padova", Padua, Italy.

Background: Encroachment on the orbital cavity represents a challenge in the management of sinonasal cancer. Criteria guiding orbital preservation lack univocal consensus. Stage of orbital involvement is best assessed through magnetic resonance imaging (MRI). Read More

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In vivo interactome profiling by enzyme-catalyzed proximity labeling.

Cell Biosci 2021 Jan 29;11(1):27. Epub 2021 Jan 29.

Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, 94304, USA.

Enzyme-catalyzed proximity labeling (PL) combined with mass spectrometry (MS) has emerged as a revolutionary approach to reveal the protein-protein interaction networks, dissect complex biological processes, and characterize the subcellular proteome in a more physiological setting than before. The enzymatic tags are being upgraded to improve temporal and spatial resolution and obtain faster catalytic dynamics and higher catalytic efficiency. In vivo application of PL integrated with other state of the art techniques has recently been adapted in live animals and plants, allowing questions to be addressed that were previously inaccessible. Read More

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January 2021

Etiology, localization of the lesion, and prognosis for patients firstly diagnosed in ophthalmology department with oculomotor nerve palsy.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2020 Dec;45(12):1425-1430

Department of Ophthalmology, First Medical Center of PLA General Hospital, Beijing 100039, China.

Objectives: Oculomotor nerve palsy is a kind of disease with many causes, showing eye movement disorders, abnormal eyelid position, and/or damage of the pupil. The etiology of oculomotor nerve palsy in different departments is different. The study discussed the etiology, localization of the lesion, and prognosis for oculomotor nerve palsy firstly diagnosed in department of ophthalmology. Read More

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December 2020

Invasive fungal disease misdiagnosed as tumour in association with orbital apex syndrome.

BMJ Case Rep 2021 Jan 20;14(1). Epub 2021 Jan 20.

Ophthalmology, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, India.

Invasive sino-orbital aspergillosis is a rare cause of orbital apex syndrome (OAS) in immunocompetent patients and often misdiagnosed as tumour because of its aggressive nature and invasive patterns. We report a 23-year-old immunocompetent man presenting with painful progressive loss of vision, ophthalmoplegia and proptosis of the right eye suggestive of OAS. MRI with gadolinium contrast showed an enhancing heterogeneous mass filling the paranasal sinuses, extraconal space and extending up to the right orbital apex. Read More

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January 2021