28,924 results match your criteria oral intake

Masseter muscle and gingival tissue inflammatory response following treatment with high-fructose corn syrup in rats: Anti-inflammatory and antioxidant effects of kefir.

J Food Biochem 2021 Apr 16:e13732. Epub 2021 Apr 16.

Department of Medical Pharmacology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.

The aim of the study was to evaluate whether high-fructose corn syrup (HFCS) intake (20% beverages) impacts antioxidative structures and inflammation in the gingival tissue and masseter muscle of rats. Kefir was tested for its potential utility on changes induced by HFCS. Animals were randomly divided into four groups as control, kefir, HFCS, and HFCS plus kefir. Read More

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Amoxicillin oral provocation challenge in a primary care clinic: a descriptive analysis.

CMAJ Open 2021 Apr-Jun;9(2):E394-E399. Epub 2021 Apr 16.

Department of Family Medicine (Gateman), McMaster University, Kitchener, Ont.; Department of Family Medicine (Gateman), Western University, Kitchener, Ont.; North Perth Family Health Team (Rumble), Listowel, Ont.; Departments of Pediatrics and Child Health, and Food and Human Nutritional Sciences (Protudjer), University of Manitoba; George & Fay Yee Centre for Healthcare Innovation (Protudjer); The Children's Hospital Research Institute of Manitoba (Protudjer), Winnipeg, Man.; Department of Medicine (Kim), Western University; Department of Medicine (Kim), McMaster University, Kitchener, Ont.

Background: Penicillin is the most frequently reported drug allergen; however, most of these allergies are not true allergies and do not justify the prescription of alternative, less effective and more expensive antibiotic drugs. We aimed to show that patients at low risk of amoxicillin allergy can safely and efficiently undergo oral provocation challenge (OPC) by their primary care physician.

Methods: In this descriptive analysis, we conducted a retrospective chart review of all primary care patients who had undergone OPC from November 2017 to October 2019 in the Amoxicillin Allergy Clinic at the North Perth Family Health Team, Listowel, Ontario. Read More

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Appetite, oral health and weight loss in community-dwelling older men: an observational study from the Concord Health and Ageing in Men Project (CHAMP).

BMC Geriatr 2021 Apr 16;21(1):255. Epub 2021 Apr 16.

Centre for Education and Research on Ageing, Concord Clinical School, The University of Sydney, and the Ageing and Alzheimer's Institute, Concord Repatriation General Hospital, Sydney Local Health District, Concord, NSW, Australia.

Background: Unintended weight loss and the reduction in appetite are common phenomenon among older people. Reduced appetite has been linked to medication related reductions in saliva production, reduced taste ability and poor oral health. Poor appetite can result in reduced nutrient intake ensuing weight loss. Read More

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[Characterization of full term newborns with hypernatremic dehydration].

Rev Chil Pediatr 2020 Dec 8;91(6):874-880. Epub 2020 Oct 8.

Fundación Hospital Infantil Los Ángeles, San Juan de Pasto, Colombia.

Introduction: The hypernatremic neonatal dehydration is a severe condition whose incidence has increased in recent years resulting in complications leading to the hospitalization of the newborn.

Objective: Describe the clinical and laboratory characteristics of term-newborns with Hypernatremic Dehy dration diagnosis.

Patients And Method: Descriptive observational study of hospitalized term- newborns due to hypernatremic dehydration between a period from 2014 to 2016. Read More

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December 2020

Endoscopic ultrasound-guided gastroenterostomy using an oroenteric catheter-assisted technique: a retrospective analysis.

Endoscopy 2021 Apr 15. Epub 2021 Apr 15.

Interventional Endoscopy Services, California Pacific Medical Center, San Francisco, California, United States.

BACKGROUND : This study evaluated an oroenteric catheter (OEC)-assisted technique to distend the enteric loop for endoscopic ultrasound-guided gastroenterostomy (EUS-GE) in patients with gastric outlet obstruction (GOO). METHODS : Patient outcomes were reviewed. Proximal enteric loops were filled with water via an OEC (7 Fr or 8 Fr), providing a target for EUS-GE using a lumen-apposing metal stent (15-mm caliber). Read More

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Selenium Kinetics in Humans Change Following 2 Years of Supplementation With Selenomethionine.

Front Endocrinol (Lausanne) 2021 29;12:621687. Epub 2021 Mar 29.

Metabolic Modeling Services, West Lafayette, IN, United States.

Background: Selenium (Se) is a nutritionally essential trace element and health may be improved by increased Se intake. Previous kinetic studies have shown differences in metabolism of organic inorganic forms of Se [e.g. Read More

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Lumen-apposing metal stent for treatment of malignant biliary obstruction, placed through an uncovered duodenal self-expanding metal stent.

BMJ Case Rep 2021 Apr 15;14(4). Epub 2021 Apr 15.

Department of Surgery, Zealand University Hospital Koge, Køge, Denmark.

The development and refinement of endoscopic stenting techniques in recent years have made endoscopic treatment an important part of palliative care for irresectable malignant disease in the gastrointestinal tract. We present the case of a 82-year-old man with biliary obstruction and duodenal stenosis on the basis of disseminated pancreatic cancer. He was bothered by jaundice and reduced oral intake. Read More

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Oral immunotherapy in food allergies: A practical update for pediatricians.

Arch Pediatr 2021 Apr 12. Epub 2021 Apr 12.

University of Lyon 1 Claude-Bernard, Villeurbanne, France; Pediatric Pulmonology and Allergology Department, Pediatric Cystic Fibrosis Center, hôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France; CIRI - Centre International de Recherche en Infectiologie (International Center for Infectiology Research), INSERM U1111, CNRS UMR 5308, Lyon, France. Electronic address:

Food oral immunotherapy (OIT) is a promising treatment for persistent and severe food allergies (FAs) in children, but also for accelerating tolerance to cow's milk and cooked egg in young children. In the near future, pediatricians will increasingly encounter severely allergic children undergoing FA-OIT. FA-OIT consists in daily ingestion of increasing doses of the allergen during the up-dosing phase, and ingestion of a constant dose during the maintenance phase. Read More

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ALTERTASTE: improving food pleasure and intake of oncology patients receiving chemotherapy.

Future Oncol 2021 Apr 16. Epub 2021 Apr 16.

Department of Health Sciences, Section of Clinical Pharmacology & Oncology, University of Florence, Viale Pieraccini, 6, Florence, 50139, Italy.

ALTERTASTE is a prospective study to evaluate changes in taste/flavor perception and food preferences in patients treated with adjuvant or neoadjuvant chemotherapy for breast or colorectal cancer. The study adopts a longitudinal approach. Taste and odor responsiveness, food preferences and habits, emotions elicited by foods, and quality of life will be measured at six-time points: before chemotherapy (T0), after two cycles (T1, after around 1 month), after four cycles (T2, after around 2 months), after six cycles (T3, after around 4 months), at the end of chemotherapy (T4, after around 6 months) and 3 months after the conclusion of the therapy (T5). Read More

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Longitudinal comparisons of a whole-mouth taste test to clinician-rated and patient-reported outcomes of dysgeusia postradiotherapy in patients with head and neck cancer and associations with oral intake.

Head Neck 2021 Apr 15. Epub 2021 Apr 15.

Greater Baltimore Medical Center, The Milton J Dance, Jr. Head and Neck Center, Head & Neck Surgery, Johns Hopkins Voice Center at GBMC, Baltimore, Maryland, USA.

Background: After head and neck cancer (HNC) treatment, dysgeusia may be a barrier to oral intake. In this exploratory study, we prospectively examined taste perception, clinician-rated (CRO) and patient-reported (PRO) taste changes and their effect on oral intake postradiotherapy.

Methods: Twenty-eight patients were assessed at baseline, treatment weeks 2 and 4, and 1, 3, and 6 months post-treatment using a whole-mouth taste test and associated CRO and subjective PRO measures. Read More

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Novel hybrid endoscopy-assisted larynx-preserving esophagectomy for cervical esophageal cancer (with video).

Jpn J Clin Oncol 2021 Apr 14. Epub 2021 Apr 14.

Division of Esophageal Surgery, National Cancer Center Hospital, Tokyo, Japan.

Hybrid endoscopy-assisted larynx-preserving esophagectomy is developed for cervical esophageal squamous cell carcinoma encroaching or extending above the upper esophageal sphincter. First, a cervical incision was surgically performed followed by cervical lymph node dissection. Second, the margin of cervical esophageal squamous cell carcinoma was endoscopically identified with iodine staining and marked endoscopically followed by semi-circumferential or circumferential endoscopic full-thickness excision around the lumen of the esophagus. Read More

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Beneficial effects of proximal intestinal bypass reconstruction on glucose metabolism in a type 2 diabetes animal model: a possible reconstruction strategy for diabetic gastric cancer patients.

Ann Surg Treat Res 2021 Apr 30;100(4):218-227. Epub 2021 Mar 30.

Gastric Cancer Center, Yonsei Cancer Center, Yonsei University Health System, Seoul, Korea.

Purpose: Proximal intestinal bypass (PIB), such as Billroth II or Roux-en-Y gastrojejunostomy after curative distal gastrectomy for gastric cancer induces beneficial effects on glycemic control in patients with type 2 diabetes. We aimed to characterize the long-term evolution of pancreatic beta cells and insulin signaling in target tissue after a PIB procedure.

Methods: Zucker diabetic fatty rats were randomly assigned to the PIB, sham-operated PIB pair-fed, and fed groups. Read More

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Dysosmia and drug tolerance with use of venlafaxine.

BMJ Case Rep 2021 Apr 14;14(4). Epub 2021 Apr 14.

Community Health and Family Medicine, University of Florida Health, Gainesville, Florida, USA

A 57-year-old woman presented with a 1-year history of major depressive disorder. She was started on venlafaxine XR 75 mg orally daily and a few days later developed severe dysosmia to foods she used to enjoy. She never had previous problems with smell or taste. Read More

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Enhanced Recovery after Surgery: Benefits for the Fetal Surgery Patient.

Fetal Diagn Ther 2021 Apr 14:1-8. Epub 2021 Apr 14.

Department of Anesthesiology, Perioperative and Pain Medicine,Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.

Background: The fetoscopic approach to the prenatal closure of a neural tube defect (NTD) may offer similar advantages to the newborn compared to prenatal open closure of a NTD, with a reduction in maternal risks. Enhanced recovery after surgery (ERAS) protocols have been applied to different surgical procedures with documented advantages. We modified the perioperative care of patients undergoing in utero repair of myelomeningocele with the goal of enhancing the recovery. Read More

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Laparoscopic versus EUS-guided gastroenterostomy for gastric outlet obstruction: an international multicenter propensity score-matched comparison (with video).

Gastrointest Endosc 2021 Apr 11. Epub 2021 Apr 11.

Department of Gastroenterology and Hepatology, University Hospitals Gasthuisberg, University of Leuven, Leuven, Belgium.

Background And Aims: In the management of gastric outlet obstruction (GOO), EUS-guided gastroenterostomy (EUS-GE) seems safe and more effective than enteral stent placement. However, comparisons with laparoscopic gastroenterostomy (L-GE) are scarce. Our aim was to perform a propensity score-matched comparison between EUS-GE and L-GE. Read More

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Elution study of acrylic monomers from orthodontic materials using high performance liquid chromatography (HPLC).

J Orofac Orthop 2021 Apr 14. Epub 2021 Apr 14.

Institute of Dental, Oral and Maxillary Medicine, Department of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Aßmannshauser Str. 4-6, 14197, Berlin, Germany.

Purpose: Main goal of the study was the identification and quantitative analysis of monomer elution from materials commonly used in fixed orthodontic therapy. Studies have shown severe health effects of monomers including cytotoxic, allergenic or mutagenic potential and endocrine changes. This in vitro study focusses primarily on five resins which are usually processed intraorally and remain in the oral cavity long-term. Read More

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Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.

Biol Trace Elem Res 2021 Apr 13. Epub 2021 Apr 13.

College of Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, Shandong, China.

As a highly toxic heavy metal, chromium has caused a certain threat to public health and livestock breeding in recent years. In poultry, as one of our most commonly consumed meat product, its health issues will seriously threaten the safety of human life. As previous studies have confirmed, when cells are stimulated by the external environment, mitochondria, as an organelle that provides energy to the cells, can cause damage and autophagy. Read More

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A Case of SGLT2 Inhibitor-Associated Euglycemic Diabetic Ketoacidosis Following Coronary Artery Bypass Surgery.

AACE Clin Case Rep 2021 Jan-Feb;7(1):20-22. Epub 2020 Dec 28.

Division of Endocrinology, Department of Medicine, Maimonides Medical Center, Brooklyn, New York.

Objective: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a novel group of oral hypoglycemic agents with multiple proven beneficial effects. However, their use has been associated with euglycemic diabetic ketoacidosis (DKA), typically triggered by risk factors such as acute illness, surgery, and decreased calorie intake. Therefore, it is recommended that patients discontinue SGLT2 inhibitors at least 24 hours before surgery to minimize this risk. Read More

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December 2020

Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice.

Sci Rep 2021 Apr 13;11(1):8060. Epub 2021 Apr 13.

Department of Cardiometabolic Diseases Research, Boehringer Ingelheim Pharma GmbH & Co., Biberach, Germany.

Dipeptidyl peptidase IV (DPP-IV) inhibitors improve glycemic control by prolonging the action of glucagon-like peptide-1 (GLP-1). In contrast to GLP-1 analogues, DPP-IV inhibitors are weight-neutral. DPP-IV cleavage of PYY and NPY gives rise to PYY and NPY which exert potent anorectic action by stimulating Y2 receptor (Y2R) function. Read More

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The evolving epidemiology of nasopharyngeal carcinoma.

Cancer Epidemiol Biomarkers Prev 2021 Apr 13. Epub 2021 Apr 13.

Department of Medical Epidemiology and Biostatistics, Karolinska Institute.

Background: The epidemiology of nasopharyngeal carcinoma (NPC) has long been a source of fascination due to the malignancy's striking geographic distribution, the involvement of the oncogenic Epstein-Barr virus (EBV), the unique association with intake of Chinese-style salt-preserved fish, and etiologic heterogeneity by histological subtype.

Methods: This review summarizes the current epidemiological literature on NPC, highlighting recent results from our population-based case-control study in southern China.

Results: Findings from our case-control study provide new insight into the epidemiology of NPC, including a diminished role of Chinese-style salt-preserved fish, a profound impact of EBV genetic sequence variation, modest positive associations with passive smoking and household air pollution, and possible effects of oral health and the oral microbiome. Read More

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A gut-intrinsic melanocortin signalling complex augments L cell secretion in humans.

Gastroenterology 2021 Apr 10. Epub 2021 Apr 10.

Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, SA 5042, Australia. Electronic address:

Objective: Hypothalamic melanocortin 4 receptors (MC4R) are a key regulator of energy homeostasis. Brain-penetrant MC4R agonists have failed, as concentrations required to suppress food intake also increase blood pressure. However, peripherally located MC4R may also mediate metabolic benefits of MC4R activation. Read More

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Potential for Manganese-Induced Neurologic Harm to Formula-Fed Infants: A Risk Assessment of Total Oral Exposure.

Environ Health Perspect 2021 Apr 13;129(4):47011. Epub 2021 Apr 13.

Minnesota Department of Health, Saint Paul, Minnesota, USA.

Background: High oral exposure and biological vulnerabilities may put formula-fed infants at risk for manganese-induced neurotoxicity.

Objectives: We sought to characterize manganese concentrations in public drinking water and prepared infant formulas commonly purchased in the United States, integrate information from these sources into a health risk assessment specific to formula-fed infants, and examine whether households that receive water with elevated manganese concentrations avoid or treat the water, which has implications for formula preparation.

Methods: Manganese was measured in 27 infant formulas and nearly all Minnesota community public water systems (CPWS). Read More

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Effect of preoperative oral liquid carbohydrate intake on blood glucose, fasting-thirst, and fatigue levels: a randomized controlled study.

Braz J Anesthesiol 2021 Apr 9. Epub 2021 Apr 9.

Erciyes University, Faculty of Health Sciences/Women's Health and Childbirth Nursing, Kayseri, Turkey.

Background: This study aimed to analyze the effects of preoperative oral intake of liquid carbohydrate on postoperative blood glucose, fasting-thirst, and fatigue levels in patients undergoing arthroscopic surgery.

Methods: This randomized controlled clinical trial enrolled 82 patients, who were scheduled to undergo arthroscopic surgery, and divided them into two groups: (1) those who consumed a carbohydrate-rich drink and (2) those not consuming anything after midnight. Pre- and postoperative fasting-thirst (visual analog scale) and blood glucose levels were measured. Read More

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Subcutaneous administration of levothyroxine: a novel approach to refractory hypothyroidism - A review and a case report.

Arch Endocrinol Metab 2021 Apr 12. Epub 2021 Apr 12.

Department of Internal Medicine I, Paracelsus Medical University of Salzburg, Salzburg, Austria.

Treatment-refractory hypothyroidism is a common clinical finding. Substantial causes include poor compliance and intake failure as well as gastrointestinal diseases, such as inflammatory bowel disease and short bowel syndromes. Increasing oral dosage of levothyroxine (LT4) is not always effective. Read More

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Successful Treatment of Protein-Losing Enteropathy After Superior Mesenteric Artery Occlusion without Surgery.

Am J Case Rep 2021 Apr 12;22:e931114. Epub 2021 Apr 12.

Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.

BACKGROUND Protein-losing enteropathy as a complication of superior mesenteric artery occlusion is extremely rare and severe, and sometimes requires intestinal resection. However, the ideal treatment strategy has not yet been determined. CASE REPORT A 77-year-old man with underlying hypertension and diabetes was admitted to the Emergency Department with acute abdominal pain after eating. Read More

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Lingual Exercise in Older Veterans With Dysphagia: A Pilot Investigation of Patient Adherence.

J Speech Lang Hear Res 2021 Apr 12:1-13. Epub 2021 Apr 12.

Department of Communication Sciences and Disorders, University of Wisconsin-Madison.

Purpose Adherence is a concern in dysphagia management. Poor adherence with recommendations can negatively affect treatment efficacy and patient outcomes. For exercise-based therapies, low adherence can alter the dose of exercise delivered to the muscle, which can diminish impact of exercise. Read More

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Spinal Anesthesia is Superior to General Anesthesia for Percutaneous Achilles Tenotomy in Infants.

J Pediatr Orthop 2021 Apr 12. Epub 2021 Apr 12.

Departments of Clinical Anesthesia Clinical Orthopedic Surgery Orthopedic Surgery Biostatistician, Indiana University School of Medicine, Indianapolis, IN.

Background: Concern about the effects of inhaled, halogenated anesthetics on neurodevelopment of infants has renewed interest in regional anesthesia as an alternative to general anesthesia (GA). Infants undergoing percutaneous Achilles tenotomy (PAT) are well suited for spinal anesthesia (SP).

Methods: Thirty infants (mean age: 2. Read More

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Increased Leg Strength After Concurrent Aerobic and Resistance Exercise Training in Older Adults Is Augmented by a Whole Food-Based High Protein Diet Intervention.

Front Sports Act Living 2021 26;3:653962. Epub 2021 Mar 26.

School of Health and Human Performance, Dublin City University, Dublin, Ireland.

Most studies in older adults have utilized powdered protein supplements or oral nutrition solutions as a source of additional dietary protein, but whole foods may provide a greater anabolic stimulus than protein isolated from food matrices. Therefore, the present study investigated a concurrent aerobic and resistance exercise training program in older adults, in the absence or presence of a high protein whole food-based dietary intervention, for effects on strength, physical function, and body composition. Community-dwelling older adults ( = 56; M/F, 28/28; age, 69. Read More

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Effects of Apple Form on Energy Intake During a Mid-Afternoon Snack: A Preload Paradigm Study in School-Aged Children.

Front Nutr 2021 26;8:620335. Epub 2021 Mar 26.

Centre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, Université Bourgogne Franche-Comté, Dijon, France.

Consuming foods with a form or a texture that requires longer oral processing is a way to decrease food intake. Although this approach is promising for leveraging healthier eating patterns in adults, it has never been explored in children. This study evaluated whether starting a mid-afternoon snack by eating either apple segments or applesauce would modify hunger and subsequent food intake during this meal. Read More

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Laparoscopic versus open radical antegrade modular pancreatosplenectomy for pancreatic cancer: a single-institution comparative study.

Gland Surg 2021 Mar;10(3):1057-1066

Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Background: Laparoscopic distal pancreatosplenectomy is an effective and safe surgical modality for treating benign and borderline distal pancreatic tumors, but rarely for pancreatic cancer. This study aimed to compare the feasibility and safety of laparoscopic and open radical antegrade modular pancreatosplenectomy for pancreatic cancer.

Methods: Fifty-one patients with pancreatic cancer who underwent radical antegrade modular pancreatosplenectomy at Ningbo Medical Center Lihuili Hospital between January 2014 and July 2018 were enrolled. Read More

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