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The Belgian DNA Debate: An Online Deliberative Platform on the Ethical, Legal, and Social Issues of Genomics.

Public Health Genomics 2021 May 5:1-11. Epub 2021 May 5.

Cancer Centre, Sciensano, Brussels, Belgium.

Introduction: Genomics is increasingly being implemented in the society. To fully realise this implementation, citizens should be consulted about their perspectives on genomics and its associated ethical, legal, and social issues (ELSI) to enable them to co-create with experts a society-supported framework in genomics.

Methods: A Belgian online DNA debate was organised, where 1,127 citizens contributed to its deliberative platform. Read More

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Ethical implications of AI in robotic surgical training: A Delphi consensus statement.

Eur Urol Focus 2021 Apr 30. Epub 2021 Apr 30.

Wellcome/ESPRC Centre for Interventional and Surgical Sciences (WEISS), University College London.

Context: As the role of AI in healthcare continues to expand there is increasing awareness of the potential pitfalls of AI and the need for guidance to avoid them.

Objectives: To provide ethical guidance on developing narrow AI applications for surgical training curricula. We define standardised approaches to developing AI driven applications in surgical training that address current recognised ethical implications of utilising AI on surgical data. Read More

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Costs, Evidence, Context and Values: Journalists' and Policy Experts' Recommendations for U.S. Health Policy Coverage.

Health Commun 2021 May 3:1-10. Epub 2021 May 3.

Journalism Department, University of Florida.

Health policy plays a critical role in determining a state's or nation's overall population health, and health system change has been a priority for a majority of Americans for at least a decade. News coverage can influence health policy development, but little research has examined the quality of that coverage, in part because no consensus exists regarding what information health policy stories should include. This paper describes a series of in-depth interviews with eight health policy experts and 12 experienced journalists who have covered health policy. Read More

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Fisherfolk's Perception of and Attitude to Solid Waste Disposal: Implications for Health, Aquatic Resources, and Sustainable Development.

Justice Mensah

J Environ Public Health 2021 15;2021:8853669. Epub 2021 Apr 15.

Directorate of Academic Planning and Quality Assurance, University of Cape Coast, Cape Coast, Ghana.

The study explored fisherfolk's perception and attitude in regard to solid waste disposal and the implications of these for public health, aquatic resources, and sustainable development (SD) in a Ghanaian fishing community. Qualitative data were obtained from 37 purposively targeted participants comprising 34 fisherfolk, an environmental health expert, a water and sanitation expert, and a fisheries and aquatic sciences expert through in-depth interviews and focus group discussions. Data were analysed thematically guided by the most significant stories. Read More

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How to Manage COVID-19 Vaccination in Immune-Mediated Inflammatory Diseases: An Expert Opinion by IMIDs Study Group.

Front Immunol 2021;12:656362. Epub 2021 Apr 15.

Gastroenterology Unit, ASST Fatebenefratelli-Sacco, Department of Biomedical and Clinical Sciences (DIBIC) L. Sacco, Università degli Studi di Milano, Milan, Italy.

Since March 2020, the outbreak of Sars-CoV-2 pandemic has changed medical practice and daily routine around the world. Huge efforts from pharmacological industries have led to the development of COVID-19 vaccines. In particular two mRNA vaccines, namely the BNT162b2 (Pfizer-BioNTech) and the mRNA-1273 (Moderna), and a viral-vectored vaccine, i. Read More

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Development and validation of a knowledge, attitude and practice questionnaire of personal use of tranquilizers.

Drug Alcohol Depend 2021 Apr 24;224:108730. Epub 2021 Apr 24.

Department of Preventive Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBER-ESP), Madrid, Spain; Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. Electronic address:

Background: Tranquilizer misuse is insufficiently acknowledged as a public health problem despite its alarming consequences. Instruments to measure psychosocial factors related to tranquilizer misuse are lacking. We aimed to develop and validate a Knowledge, Attitude and Practice questionnaire of tranquilizer misuse by adults in Spain. Read More

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Validation of the Spanish-Mexican Version of the Australian Breastfeeding Attitude Questionnaire in Higher Education Health Students.

Int J Environ Res Public Health 2021 Apr 27;18(9). Epub 2021 Apr 27.

Cuerpo Académico UDG-CA-454 "Alimentación y Salud en el proceso Salud-Enfermedad", Departamento de Clínicas de la Reproducción Humana, Crecimiento y Desarrollo Infantil, Centro Universitario de Ciencias de la Salud (CUCS) Universidad de Guadalajara (UdeG), México, Calle Hospital 320, Colonia El Retiro, Guadalajara 44280, Jalisco, Mexico.

Positive attitudes towards breastfeeding in health professionals/students have been associated with increasing their confidence to provide support and accompaniment to mothers. In Mexico, there is no valid/reliable tool to assess attitudes towards breastfeeding in this population. The Australian Breastfeeding Attitudes (and Knowledge) Questionnaire (ABAQ) measures attitudes in the Australian population. Read More

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Creating Standardized Tools for the Pharmacist-Led Assessment and Pharmacologic Management of Adult Canadians Wishing to Quit Smoking: A Consensus-Based Approach.

Pharmacy (Basel) 2021 Apr 14;9(2). Epub 2021 Apr 14.

School of Pharmacy, University of Waterloo, Kitchener, ON N2G 1C5, Canada.

Tobacco use continues to be recognized as the single most preventable cause of death worldwide. As the gatekeepers of and experts on pharmacotherapy, pharmacists play a vital role in facilitating smoking cessation. While existing frameworks have enabled pharmacists to provide smoking cessation services in Canada for many years, the way in which they are delivered vary considerably across the nation. Read More

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First Data in the Process of Validating a Tool to Evaluate Knowledge, Attitude, and Practice of Healthcare Providers in Oral Care of Institutionalized Elderly Residents: Content Validity, Reliability and Pilot Study.

Int J Environ Res Public Health 2021 Apr 14;18(8). Epub 2021 Apr 14.

School of Nursing, Tung Wah College, Hong Kong, China.

Background: Oral health of elderly people is a global concern. Poor oral health in institutionalized elderly people has been attributed to poor knowledge, attitude, and practice (KAP) of healthcare providers. However, no validated KAP tool is available yet. Read More

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Public Preferences in Resource Allocation for Insurance Coverage of Dental Implant Service in South Korea: Citizens' Jury.

Int J Environ Res Public Health 2021 Apr 14;18(8). Epub 2021 Apr 14.

Department of Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.

The Korean government sought to include dental implant services for the elderly in the benefits package of the national health insurance. In 2014, the Citizens' Jury was held to discuss the topic, during which thirty jurors, randomly selected from the 2665 applicants, participated in a day-long deliberation process after having an information session on the topic by a team of experts. There was a substantial shift in opinion during the deliberation session toward a more cost-conscious view. Read More

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Validity and Reliability of Self-Assessment Tool for Risk Prioritization Following Exposure to Tuberculosis in a Hospital Setting.

Int J Environ Res Public Health 2021 Apr 9;18(8). Epub 2021 Apr 9.

Division of Occupational Medicine, Department of Community Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

The Modified Self-Assessment (MSA) and Present Self-Assessment (PSA) forms are questionnaires used to prioritize the risk of infection of health workers exposed to tuberculosis (TB) in Srinagarind Hospital in Thailand. As MSA was developed from PSA, the validity and reliability of MSA need to be assessed. The research aim is to examine the content validity of MSA and to assess the respective reliability of MSA and PSA vis-à-vis expert opinion. Read More

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Hijacking of the aircraft OK ADN L410 TURBOLET on June 8, 1972 - Forensic Medical Notes.

Cesk Patol 2021 ;57(1):11-16

On 8 June 1972, the Czechoslovak OK DNN aircraft carrier L410 Turbolet was delivered to the regular line Marianske Lazne - Prague to the Federal Republic of Germany. About 8 minutes after the launch from Marianske Lazne Airport, the likely head of the group of kidnappers threw the captain of the plane. During the fight with one of the passenger, the head of the group of kidnappers killed the captain of the aircraft by a shot from 7. Read More

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Mapping the Educational Environment of Genomics and Pharmacogenomics in the United Arab Emirates: A Mixed-Methods Triangulated Design.

OMICS 2021 Apr 27. Epub 2021 Apr 27.

Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.

Pharmacogenomics (PGx) education is crucial to support the effective delivery of PGx services in any health care system. We mapped the current educational environment of genomics and PGx in the United Arab Emirates (UAE) and assessed the readiness of the accredited higher education system to move forward with the implementation of PGx in the country. We employed a mixed-methods triangulated approach to map the PGx educational environment in UAE. Read More

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Identifying Anatomical Structures on Ultrasound: Assistive Artificial Intelligence in Ultrasound-Guided Regional Anesthesia.

Clin Anat 2021 Apr 27. Epub 2021 Apr 27.

Department of Anaesthesia, Royal Cornwall Hospitals NHS Trust, Truro, UK.

Ultrasound-guided regional anesthesia involves visualizing sono-anatomy to guide needle insertion and the perineural injection of local anesthetic. Anatomical knowledge, and recognition of anatomical structures on ultrasound, is known to be imperfect amongst anesthesiologists. This investigation evaluates the performance of an assistive artificial intelligence (AI) system in aiding the identification of anatomical structures on ultrasound. Read More

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Development and validation of a questionnaire for assessing preventive practices and barriers among health care workers in COVID-19 pandemic.

Indian J Med Microbiol 2021 Apr 23. Epub 2021 Apr 23.

Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.

Objectives: COVID-19 has affected thousands of health care workers worldwide. Suboptimal infection control practices have been identified as important risk factors. The objective of this study was to develop and validate a questionnaire to holistically assess the preventive practices of health care workers related to COVID-19 and identify the reasons for shortcomings therein. Read More

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Research priorities to fill knowledge gaps on ASF seasonality that could improve the control of ASF.

EFSA J 2021 Apr 19;19(4):e06550. Epub 2021 Apr 19.

The European Commission requested EFSA to provide study designs for the investigation of four research domains according to major gaps in knowledge identified by EFSA in a report published in 2019: i) the patterns of seasonality of ASF in wild boar and domestic pigs in the EU; ii) the ASF epidemiology in wild boar; iii) ASF virus (ASFV) survival in the environment and iv) ASF transmission by vectors. In this Scientific Opinion, the first research domain on ASF seasonality is addressed. Therefore, five research objectives were proposed by the working group and broader ASF expert networks, such as ASF stop, ENETWILD, VectorNet, AHAW network and the AHAW Panel Experts. Read More

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Recommendations for the pragmatic use of ultrasound in rheumatoid arthritis by the GEISPER French group.

Joint Bone Spine 2021 Apr 20:105187. Epub 2021 Apr 20.

Ambroise Paré Hospital, APHP, Université Versailles-Saint-Quentin en Yvelines - Rheumatology, Boulogne-Billancourt, France. Electronic address:

Objective: To develop recommendations for the appropriate use of ultrasound in the management of rheumatoid arthritis (RA) in routine practice based on data from the literature and of experts opinion.

Methods: Based on a systematic literature review, a scientific committee decided on themes and relevant questions to draw up an initial draft of recommendations. These recommendations were submitted to a group of experts in ultrasound in rheumatic and musculoskeletal diseases using a Delphi method, which produced preliminary recommendations. Read More

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What do Final Year Medical Students in Germany know and think about Climate Change? - The ClimAttitude Study.

Med Educ Online 2021 Dec;26(1):1917037

Department of General Internal Medicine and Psychosomatics, University of Heidelberg Medical Hospital, Heidelberg, Germany.

Climate change (CC) is adversely affecting human health and will become far more dangerous in the future, if no substantial measures are taken. Young people in particular are taking an energetic stand for CC awareness. Some CC experts argue that medical doctors are especially well positioned to inform about the impact of CC on public health, as it is well established that they are among the most trusted members of society. Read More

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December 2021

Early detection of young children at risk of autism spectrum disorder at well-baby clinics in the Netherlands: Perspectives of preventive care physicians.

Autism 2021 Apr 22:13623613211009345. Epub 2021 Apr 22.

Karakter Child and Adolescent Psychiatry University Centre, The Netherlands.

Lay Abstract: To improve early detection of autism spectrum disorder in preventive care, a Dutch guideline was developed 5 years ago. The guideline provides preventive care physicians at well-baby clinics action-oriented advice and describes a step-by-step approach for children identified at an increased risk for autism spectrum disorder during general healthcare surveillance. The present qualitative study evaluated adherence to the guideline and studied barriers regarding early detection of autism spectrum disorder at well-baby clinics. Read More

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Guidelines on the diagnosis, clinical assessments, treatment and management for CLN2 disease patients.

Orphanet J Rare Dis 2021 Apr 21;16(1):185. Epub 2021 Apr 21.

Evelina, London Children's Hospital, London, UK.

Background: CLN2 disease (Neuronal Ceroid Lipofuscinosis Type 2) is an ultra-rare, neurodegenerative lysosomal storage disease, caused by an enzyme deficiency of tripeptidyl peptidase 1 (TPP1). Lack of disease awareness and the non-specificity of presenting symptoms often leads to delayed diagnosis. These guidelines provide robust evidence-based, expert-agreed recommendations on the risks/benefits of disease-modifying treatments and the medical interventions used to manage this condition. Read More

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Outcomes of acute respiratory distress syndrome in COVID-19 patients compared to the general population: a systematic review and meta-analysis.

Expert Rev Respir Med 2021 May 5:1-8. Epub 2021 May 5.

Department of Internal Medicine, Kamineni Academy of Medical Sciences and Research Centre, Hyderabad, India.

Introduction: Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) often leads to mortality. Outcomes of patients with COVID-19-related ARDS compared to ARDS unrelated to COVID-19 is not well characterized.

Areas Covered: We performed a systematic review of PubMed, Scopus, and MedRxiv 11/1/2019 to 3/1/2021, including studies comparing outcomes in COVID-19-related ARDS (COVID-19 group) and ARDS unrelated to COVID-19 (ARDS group). Read More

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[Attitude towards vaccination against SARS-CoV-2 : Survey among employees in hospitals before and after the start of vaccinations in German hospitals].

Med Klin Intensivmed Notfmed 2021 Apr 20. Epub 2021 Apr 20.

ARDS und ECMO Zentrum Köln-Merheim, Kliniken der Stadt Köln und Universität Witten/Herdecke, Köln, Deutschland.

Background: The vaccinations against the "severe acute respiratory syndrome coronavirus type 2" (SARS-CoV‑2) play a decisive role in the global fight against the coronavirus pandemic. In the population, but also among health care workers (HCWs), there were concerns and skepticism about vaccinations even before the corona pandemic.

Methods: An online survey on the attitude of HCWs to vaccination against SARS-CoV‑2 was carried out in December (December 3rd-December 12th, 2020) before and in February (February 1st-February 10th, 2021) after the start of the vaccinations. Read More

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A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch.

Genome Med 2021 Apr 19;13(1):61. Epub 2021 Apr 19.

Centre for Genomic Pathogen Surveillance, Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, Oxfordshire, UK.

Background: Antimicrobial-resistant (AMR) Neisseria gonorrhoeae is an urgent threat to public health, as strains resistant to at least one of the two last-line antibiotics used in empiric therapy of gonorrhoea, ceftriaxone and azithromycin, have spread internationally. Whole genome sequencing (WGS) data can be used to identify new AMR clones and transmission networks and inform the development of point-of-care tests for antimicrobial susceptibility, novel antimicrobials and vaccines. Community-driven tools that provide an easy access to and analysis of genomic and epidemiological data is the way forward for public health surveillance. Read More

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Knowledge, attitude, perception, and preventative practices towards COVID-19 in sub-Saharan Africa: A scoping review.

PLoS One 2021 19;16(4):e0249853. Epub 2021 Apr 19.

Discipline of Public Health Medicine, School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Howard Campus, Durban, South Africa.

Background: Knowledge, attitudes, perception, and preventative practices regarding coronavirus- 2019 (COVID-19) are crucial in its prevention and control. Several studies have noted that the majority of people in sub-Saharan African are noncompliant with proposed health and safety measures recommended by the World Health Organization (WHO) and respective country health departments. In most sub-Saharan African countries, noncompliance is attributable to ignorance and misinformation, thereby raising questions about people's knowledge, attitudes, perception, and practices towards COVID-19 in these settings. Read More

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Standardizing the Diagnostic Evaluation of Nonarthritic Hip Pain Through the Delphi Method.

Orthop J Sports Med 2021 Apr 5;9(4):2325967121991213. Epub 2021 Apr 5.

Boston Children's Hospital, Boston, Massachusetts, USA.

Background: Femoroacetabular impingement and acetabular dysplasia have gained increased attention as nonarthritic sources of pain and dysfunction in young, active patients. To date, no standardized approach to the diagnostic evaluation of nonarthritic hip pain has been identified, as previous work has focused on the diagnostic evaluation and management of patients with femoroacetabular impingement undergoing hip arthroscopy.

Purpose: To explore the standard diagnostic evaluation practice of experts in the field of hip preservation surgery and combine their expertise through the Delphi method to form a standardized approach to the diagnostic evaluation of patients with nonarthritic hip pain. Read More

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Identifying HIV-related digital social influencers using an iterative deep learning approach.

AIDS 2021 May;35(Suppl 1):S85-S89

Department of Emergency Medicine.

Objectives: Community popular opinion leaders have played a critical role in HIV prevention interventions. However, it is often difficult to identify these 'HIV influencers' who are qualified and willing to promote HIV campaigns, especially online, because social media influencers change frequently. We sought to use an iterative deep learning framework to automatically discover HIV-related online social influencers. Read More

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A virtual faculty exchange program enhances dermatology resident education in the COVID-19 era: a survey study.

Dermatol Online J 2021 Mar 15;27(3). Epub 2021 Mar 15.

Department of Dermatology, University of California Irvine, Irvine, CA.

One of the many consequences of the COVID-19 pandemic was the cancelation of the 2020 American Academy of Dermatology Annual Meeting. This conference historically features lectures from world-renowned experts in all areas of dermatology, thus providing an important educational experience for dermatology residents. We hypothesized that the cancellation of this meeting produced a substantial educational loss for dermatology residents. Read More

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Consensus on Screening, Diagnosis, and Staging Tools for Prostate Cancer in Developing Countries: A Report From the First Prostate Cancer Consensus Conference for Developing Countries (PCCCDC).

JCO Glob Oncol 2021 Apr;7:516-522

Hospital Beneficiencia Portuguesa de São Paulo, São Paulo, Brazil.

Purpose: To generate and present the survey results on critical issues relevant to screening, diagnosis, and staging tools for prostate cancer (PCa) focused on developing countries.

Methods: A total of 36 of 300 questions concern the main areas of interest of this paper: (1) screening, (2) diagnosis, and (3) staging for various risk levels of PCa in developing countries. A panel of 99 international multidisciplinary cancer experts voted on these questions to create recommendations for screening, diagnosing, and staging tools for PCa in areas of limited resources discussed in this manuscript. Read More

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Consensus on Prostate Cancer Treatment of Localized Disease With Very Low, Low, and Intermediate Risk: A Report From the First Prostate Cancer Consensus Conference for Developing Countries (PCCCDC).

JCO Glob Oncol 2021 Apr;7:523-529

A Beneficiência Portuguesa de São Paulo, São Paulo, Brazil.

Purpose: A group of international urology and medical oncology experts developed and completed a survey on prostate cancer (PCa) in developing countries. The results are reviewed and summarized, and recommendations on consensus statements for very low-, low-, and intermediate-risk PCa focused on developing countries were developed.

Methods: A panel of experts developed more than 300 survey questions of which 66 questions concern the principal areas of interest of this paper: very low, low, and intermediate risk of PCa in developing countries. Read More

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Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer Consensus Conference for Developing Countries.

JCO Glob Oncol 2021 Apr;7:530-537

Hospital do Câncer AC Camargo, São Paulo, Brazil.

Purpose: To generate and present survey results on important issues relevant to treatment and follow-up of localized and locally advanced, high-risk prostate cancer (PCa) focusing on developing countries.

Methods: A panel of 99 PCa experts developed more than 300 survey questions of which 67 questions concern the main areas of interest of this article: treatment and follow-up of localized and locally advanced, high-risk PCa in developing countries. A larger panel of 99 international multidisciplinary cancer experts voted on these questions to create the recommendations for treatment and follow-up of localized and locally advanced, high-risk PCa in areas of limited resources discussed in this article. Read More

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