23,626 results match your criteria one-way anova

Cariogenic Potential of Human and Bovine Milk on Enamel Demineralization.

Caries Res 2021 Jun 15:1-8. Epub 2021 Jun 15.

Piracicaba Dental School, UNICAMP, Piracicaba, Brazil.

The higher cariogenicity of human milk when compared with bovine milk is still a debatable subject. Therefore, we evaluated the effect of human or bovine milk exposure on biofilm composition and enamel demineralization using a validated cariogenic biofilm model. Streptococcus mutans UA159 biofilms (n = 8) were grown on human saliva-coated bovine enamel slabs of known surface hardness. Read More

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The associations between smart device use and psychological distress among secondary and high school students in Kuwait.

PLoS One 2021 15;16(6):e0251479. Epub 2021 Jun 15.

Department of Physical Education, College of Basic Education, The Public Authority for Applied Education and Training, Kuwait.

Background: Smart devices (SDs) are widely used among adolescents. Numerous studies have recommended further research on this topic to find out the prevalence of SD overuse among school students and to what extent this is associated with psychological distress. The present study aimed to investigate the pattern of SD use among secondary and high school students in the state of Kuwait, as well as the possible associations with psychological problems, weight, physical activity, and school performance. Read More

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Overall survival in metastatic melanoma correlates with pembrolizumab exposure and T cell exhaustion markers.

Pharmacol Res Perspect 2021 Aug;9(4):e00808

Calvary Mater Hospital Newcastle, Waratah, NSW, Australia.

Trial data support an absence of an exposure-survival relationship for pembrolizumab. As these relationships remain unexamined in a real-world setting, we determined them in metastatic melanoma prospectively in an observational study. Translational objectives included identifying biomarkers of progressive disease (PD). Read More

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High-fidelity simulation is associated with good discriminability in emergency medicine residents' in-training examinations.

Medicine (Baltimore) 2021 Jun;100(24):e26328

Department of Emergency Medicine, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan.

Abstract: In-training examinations (ITEs), arranged during residency training, evaluate the residents' performances periodically. There is limited literature focusing on the effectiveness of resident ITEs in the format of simulation-based examinations, as compared to traditional oral or written tests. Our primary objective is to investigate the effectiveness and discriminative ability of high-fidelity simulation compared with other measurement formats in emergency medicine (EM) residency training program. Read More

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[Feasibility study of telemedicine model for diagnosis and treatment of patients with obstructive sleep apnea hypopnea syndrome in China].

Zhonghua Yi Xue Za Zhi 2021 Jun;101(22):1671-1675

Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.

To explore the feasibility of applying telemedicine model in disease management for patients with obstructive sleep apnea hypopnea syndrome (OSAHS) in China. A total of 24 patients were enrolled with suspected OSAHS who were admitted to the Sleep Center of Peking University People's Hospital from October 2015 to September 2016. Patients were diagnosed by electronic questionnaire assessment and home sleep apnea monitoring (HSAT) and were treated with remote automatic positive airway pressure (APAP). Read More

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Comprehensive characterisation of flexural mechanical properties and a new classification for porosity of 11 contemporary ion-leaching dental restorative materials.

J Mech Behav Biomed Mater 2021 Jun 1;121:104615. Epub 2021 Jun 1.

Melbourne Dental School, The University of Melbourne, Melbourne Victoria Australia 720 Swanston St, Carlton Melbourne, VIC, 3053, Australia. Electronic address:

The objectives of this study were to evaluate 4 aspects of ion-leaching restorative materials (ILMs): 4-point bending flexural strength (4 PB-FS) and relative mechanical properties; biaxial flexural strength (B-FS) in relation to 4 PB-FS; porosity; and surface morphology. Eleven ILMs were used for the 4-point bending test. Bar-shaped (n = 15) samples were fabricated, stored in distilled water for 7 days. Read More

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Quantitative study of preoperative staging of gastric cancer using intravoxel incoherent motion diffusion-weighted imaging as a potential clinical index.

Eur J Radiol 2021 Mar 4;141:109627. Epub 2021 Mar 4.

Department of Gastrointestinal Surgery, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, 361004, China; Institute of Gastrointestinal Oncology, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, China; Xiamen Municipal Key Laboratory of Gastrointestinal Oncology, Xiamen, Fujian, 361004, China. Electronic address:

Purpose: To determine the utility of intravoxel incoherent motion (IVIM) diffusion-weighted imaging in quantitative analysis of preoperative tumor (T) and node (N) stages of gastric cancer, and to quantify the diagnostic threshold of IVIM parameters for serosal invasion and lymphatic metastasis.

Materials And Methods: From October 2016 to February 2020, 98 patients with gastric cancer who were receiving treatment in Zhongshan Hospital, China, were subject to an IVIM sequence imaging analysis. The IVIM sequence data were imported into software for post-processing of tumor regions of interest, and the IVIM parameters (the microvascular volume fraction (f), the molecular diffusion coefficient (D) and perfusion-related incoherent microcirculation (D*) were calculated. Read More

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An Advanced Communication Skills Workshop Using Standardized Patients for Senior Medical Students.

MedEdPORTAL 2021 May 27;17:11163. Epub 2021 May 27.

Professor, Department of Medicine, and Director of Medical Student Palliative and End-of-Life Care Education, Yale School of Medicine.

Introduction: Medical students often lack training in advanced communication skills encompassing emotionally fraught situations and those in which an intense emotional response is expected. Such skills are required for clinical situations encountered during residency. We created and evaluated an advanced communication skills workshop (ACSW) using standardized patients for senior medical students. Read More

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Analysis of Facial Skeletal Morphology: Nasal Bone, Maxilla, and Mandible.

Biomed Res Int 2021 24;2021:5599949. Epub 2021 May 24.

Division of Clinical Dentistry, Department of Dentistry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

The growth and development of facial bones are closely related to each other. The present study investigated the differences in the nasomaxillary and mandibular morphology among different skeletal patterns. Cephalograms of 240 participants were divided into 3 groups based on the skeletal pattern (Class I, Class II, and Class III). Read More

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The Efficacy of Little Lovely Dentist, Dental Song, and Tell-Show-Do Techniques in Alleviating Dental Anxiety in Paediatric Patients: A Clinical Trial.

Biomed Res Int 2021 23;2021:1119710. Epub 2021 May 23.

Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Al Jouf 72345, Saudi Arabia.

Introduction: Dental anxiety is a common occurrence in patients undergoing dental treatments, especially in children. The success in paedriatric dental treatments and patient comfort depends on controlling the level of patient's anxiety in clinical settings. This study is aimed at evaluating the efficacy of different techniques applied for the reduction of dental anxiety in paediatric patients. Read More

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A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test.

Int J Sports Phys Ther 2021 Jun 1;16(3):835-843. Epub 2021 Jun 1.

Wichita State University.

Background: In orthopaedic practice, it is well established that weak scapular stabilizers and an unstable scapula is related to shoulder dysfunction. Faulty scapular position has been linked to decreased scapular stability and is thought to be a result of weak or unbalanced timing in the recruitment of scapulothoracic dynamic stabilizing muscles. Kibler has described a four-type classification of scapulothoracic dysfunction. Read More

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Circadian pattern of symptom onset in patients with ST-segment elevation myocardial infarction in western Iran.

ARYA Atheroscler 2020 Nov;16(6):284-289

Cardiovascular Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background: Circadian variation is known as an important factor in acute myocardial infarction (AMI). Moreover, the circadian pattern may help in disease prevention and better medication prescription. Therefore, the aim of our study was to investigate the circadian pattern of symptom onset in patients with ST-segment elevation myocardial infarction (STEMI). Read More

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November 2020

Pharmacokinetic and pharmacodynamic interaction of Rosuvastatin calcium with guggulipid extract in rats.

Saudi J Biol Sci 2021 Jun 14;28(6):3490-3496. Epub 2021 Mar 14.

Department of Pharmacognosy, Collage of Pharmacy, King Saud university, P.O.Box 22452, Riyadh 11495, Saudi Arabia.

Background & Objectives: Rosuvastatin calcium (RC) is a potent and competitive synthetic inhibitor of HMG-CoA reductase used for the treatment of dyslipidemia. Guggulipid obtained from is used in the treatment of a wide variety of diseases such as atherosclerosis, hypercholesterolemia, rheumatism, and obesity. The present study evaluates the pharmacokinetic and pharmacodynamic interactions between RC and the standardized guggulipid extract in rats. Read More

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Effect of prosthetic framework material, cantilever length and opposing arch on peri-implant strain in an all-on-four implant prostheses.

Niger J Clin Pract 2021 Jun;24(6):866-873

Department of Prosthodontics and Dental Materials and Dean, School of Dental Medicine, University of Siena, Italy.

Aim: To evaluate the effect of prosthetic framework material and cantilever length on peri-implant strain in mandibular all-on-four implant-supported prostheses with different types of arch antagonist forces.

Materials And Methods: Models simulating a completely edentulous mandibular arch fabricated in heat-cured acrylic resin were used. On the acrylic models, four implants were placed at regions 34, 32, 42, and 44 simulating all-on-four implant placements. Read More

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Evaluation of the marginal microleakage of CAD-CAM compared with conventional interim crowns luted with different types of cement: An study.

Niger J Clin Pract 2021 Jun;24(6):828-832

Department of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan, Kingdom of Saudi Arabia.

Background: Temporary stage in crowns and bridgework plays an important role in the success and failure of the final restorations. Lack of marginal seal of the temporary restorations can lead to further complications. Recently, digital dentistry has been improved in terms of marginal integrity. Read More

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FCX, an arylidene derivative, induces apoptosis in androgen receptor-selective prostate cancer cells.

J Cancer Res Ther 2021 Apr-Jun;17(2):401-407

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.

Context: Rational screening of arylidene derivatives for biological activities has resulted in many lead molecules with anticancer properties with effective therapeutic window.

Aims: In the current study, FCX, an arylidene derivative, was screened for anticolon and prostate cancer activity.

Settings And Design: Prostate and colon cancer cell lines were used to check the FCX effect on proliferation, apoptosis, and mechanism of drug action. Read More

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Association between birthweight, cardiovascular risk factors, and depression in young Mexican adults.

Nutr Hosp 2021 Jun 14. Epub 2021 Jun 14.

Centro de Investigacion Aplicada en Ambiente y Salud (CIAAS). Facultad de Medicina/CIACYT. Universidad Autónoma de San Luis Potosí.

Background: the aim of this study was to investigate the association between birthweight, cardiovascular disease (CVD) risk factors, and depression in young Mexican adults.

Methods: birthweight reports, family history of CVD and diabetes-related diseases, anthropometrics, serum lipid profile (total cholesterol [TC], triglycerides [TG], high-density lipoprotein-cholesterol [HDL-C], low-density lipoprotein-cholesterol [LDL-C], and very-low density lipoprotein-cholesterol [VLDL-C]), and depressive symptoms were measured in 778 subjects of the UP-AMIGOS cohort study. To investigate the association between birthweight categories and CVD risk factors and depression, a one-way analysis of variance with post-hoc test was performed of quantitative variables, and 2 test for qualitative variables. Read More

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Opinions about coronavirus vaccination – the role of healthcare workers in communication in December 2020

Orv Hetil 2021 06 13;162(24):931-937. Epub 2021 Jun 13.

2 Károli Gáspár Református Egyetem, Bölcsészet- és Társadalomtudományi Kar, Pszichológiai Intézet, Személyiség- és Egészségpszichológiai Tanszék, Budapest.

Összefoglaló. Bevezetés: A koronavírus elleni védőoltással kapcsolatos vélekedések igen aktuális, társadalmi szempontból fontos területét adják az egészségmagatartással foglalkozó kutatásoknak. Célkitűzés: Vizsgálatunk a védőoltásról különbözőképpen vélekedő (oltást elutasító, oltást választó, oltáson nem gondolkodó, valamint bizonytalan) csoportok elemzését tűzte ki célul az oltás előnyeinek és hátrányainak, valamint az információforrások használatának tekintetében. Read More

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Identification of zinc pollution in rice plants based on two characteristic variables.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jun 4;261:120043. Epub 2021 Jun 4.

Communication and Electronic Engineering Institute, Qiqihar University, Qiqihar 161006, People's Republic of China.

Traditional chemical methods used to measure the zinc content in rice plants are time-consuming, laborious, requires reagents, and have a limited monitoring range, while the Raman spectroscopy method has the advantage of being fast, non-destructive, and requires no reagents. Unfortunately, the identification accuracy of the Raman partial least squares (PLS) model based on principal components is only 53.33%. Read More

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Fear of COVID-19, problems accessing medical appointments, and subjective experience of disease progression, predict anxiety and depression reactions in patients with Multiple Sclerosis.

Mult Scler Relat Disord 2021 Jun 2;53:103070. Epub 2021 Jun 2.

Psychology Department, Universidad Central "Marta Abreu" de Las Villas, Santa Clara, Cuba; CognitiON (Cuban Inicative on Cognitive Health), Santa Clara, Cuba.

Background: During the current COVID-19 pandemic there are studies that have suggested a negative impact of the pandemic on the mental health of patients with multiple sclerosis (PwMS). In this sense, several factors may be related to the increase in experiences of anxiety and depression in PwMS during the current pandemic.

Objective: In this study we first explored the reactions of anxiety, depression and fear to COVID-19 in a group of PwMS that belong to the Ibero-American region. Read More

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In vitro evaluation of the anti-proteolytic and cross-linking effect of mussel-inspired monomer on the demineralized dentin matrix.

J Dent 2021 Jun 10:103720. Epub 2021 Jun 10.

Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong. Electronic address:

Objectives: To evaluate the anti-proteolytic and cross-linking effect of N-(3,4-dihydroxyphenethyl)methacrylamide (DMA) on the demineralized dentin matrix in vitro.

Methods: Four experimental solutions were selected: 50% ethanol/water solution (Control); 1, 5, and 10 mmol/L DMA dissolved in 50% ethanol/water solution. Sound human molars were sectioned to produce dentin beams with dimension of 1×1×6 mm. Read More

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The effect of root canal preparation size and taper of middle mesial canals on fracture resistance of the mandibular molar teeth: An in vitro study.

J Endod 2021 Jun 9. Epub 2021 Jun 9.

(Associate Professor) Department of Endodontology, Faculty of Dentistry, Ege University, Izmir, Turkey. Electronic address:

Introduction: The aim of the present study was to investigate the influence of root canal preparation size and taper of middle mesial (MM) canals on fracture resistance of mandibular molars.

Methods: Fifty-five mandibular molar teeth having MM canal were selected based on the cone-beam computed tomography analysis. Following the decoronation and distal root separation procedure, the lengths of the mesial roots were standardized to 13 mm. Read More

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Occlusal Thickness and Cement-Type Effects on Fracture Resistance of Implant-Supported Posterior Monolithic Zirconia Crowns.

Int J Oral Maxillofac Implants 2021 May-Jun;36(3):485-491

Purpose: To evaluate the factors that could influence the fracture resistance of implant-supported posterior monolithic zirconia crowns.

Materials And Methods: Sixty zirconia molar crowns with three different occlusal thicknesses of 0.5, 1. Read More

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Influence of a Novel Drill Design on Heat Generation During Conventional and Guided Implant Osteotomy.

Int J Oral Maxillofac Implants 2021 May-Jun;36(3):e31-e41

Purpose: The aim of this in vitro study was to evaluate the temperature development of a novel, electropolished drill design during conventional and guided implant osteotomy in comparison to conventional drills under standardized conditions.

Materials And Methods: Single and sequential 12-mm-deep drilling protocols (guided and unguided) with a conventional (control groups) and novel drill (test groups) were performed in artificial bone blocks under external irrigation. Each drilling protocol was repeated 30 times with drill diameters of 2. Read More

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Retrospective study of the efficacy of vascularized tissue transfer for treating antibiotic-resistant bacteria-infected wound: Comparison with clean and antibiotic-sensitive bacteria-infected wound.

Medicine (Baltimore) 2021 Jun;100(23):e25907

Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul.

Abstract: If wounds are infected with bacteria resistant to an empirical antibiotic regimen, effective wound treatment will be delayed. This can delay wound healing and lengthen hospital stays, increasing the costs to patients. Long-term antibiotic use can also result in minor and major complications, such as diarrhea, antibiotic resistance, or life-threatening leukopenia. Read More

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The relationship between seeds consumption, lipid profile and body mass index among patients with cardiovascular diseases.

Rocz Panstw Zakl Hig 2021 ;72(2):145-153

Slovak University of Agriculture in Nitra, Faculty of Agrobiology and Food Resources, Department of Human Nutrition, Nitra, Slovak Republic.

Background: Cardiovascular disease (CVD) is the leading cause of death worldwide and largely preventable through improving diet quality and other lifestyle factors. In recent years, dietary recommendations have shifted towards diets high in plant-based foods and low in animal-based foods for the prevention of chronic diseases.

Objective: This study aims to evaluate the relationship between seeds consumption, lipid profile and body mass index (BMI) in a group of 889 (313 female and 576 male) randomly selected patients hospitalized in the Nitra Cardio Center, Slovakia. Read More

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January 2021

Impact of anxiety and depression on the quality of life of haemodialysis patients.

J Clin Nurs 2021 Jun 10. Epub 2021 Jun 10.

Medical Surgical Nursing Department, Faculty of Nursing, King Abdulaziz University, Jeddah, Saudi Arabia.

Aims And Objectives: This study aimed to assess the impact of anxiety and depression on the quality of life (QOL) of haemodialysis patients.

Background: The growing number of people undergoing haemodialysis therapy on a global scale is becoming a universal concern. Although haemodialysis treatment is known to affect one's psychological well-being, the impact of depression and anxiety on one's QOL has not been well addressed. Read More

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Family-Centered Social Cognitive Factors Preventing Primary Tooth Caries in Children Based on Intervention Mapping Approach.

Biomed Res Int 2021 18;2021:6626090. Epub 2021 May 18.

Population Health Research Group, Health Metrics Research Center, Iranian Institute for Health Sciences Research, ACECR, Tehran, Iran.

Background: Given the increasing prevalence of primary tooth caries in Iran and the importance of providing evidence- and theory-based family-centered prevention programs, the present study is aimed at determining the family-centered social cognitive factors preventing deciduous tooth caries among children using the intervention mapping protocol.

Methods: This cross-sectional study was performed on 240 Iranian mothers in Ilam who were randomly selected to participate in the study. The data were collected using a self-designed questionnaire including items on demographic information and social cognitive constructs (knowledge, attitude, perceived severity, perceived benefits, perceived barriers, practice guidance, perceived self-efficacy, behavior intention, subjective norms, and social norms). Read More

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The Effect of Dietary Antioxidant Supplementation in Patients with Glaucoma.

Clin Ophthalmol 2021 2;15:2293-2300. Epub 2021 Jun 2.

Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Purpose: Oxidative stress may be a risk factor for glaucoma, and many previous reports have suggested that antioxidants could be a promising treatment. Here, we investigated the effects of a novel supplement containing three food-derived antioxidants (hesperidin, crocetin, and ) on markers of oxidative stress in patients with glaucoma.

Patients And Methods: This study had a prospective, single arm design. Read More

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Supplementation of rice husk activated charcoal in feed and its effects on growth and histology of the stomach and intestines from giant trevally, .

F1000Res 2020 26;9:1274. Epub 2020 Oct 26.

Department of Aquaculture, Faculty of Marine and Fishery, Universitas Syiah Kuala, Banda Aceh, Aceh Province, 23111, Indonesia.

Research on supplementing feed with rice husk activated charcoal was carried out to determine the effect of variations in the concentration of rice husk activated charcoal on the growth and histological features of the giant trevally  intestine. This study used an experimental method with a completely randomized design consisting of six treatments and four replications, including adding activated charcoal to feed at concentrations of 0%, 1%, 1.5%, 2%, 2. Read More

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October 2020