352,246 results match your criteria odds ratios


Factors Associated With Children Diagnosed With Attention-Deficit/Hyperactivity Disorder and 30-Day Follow-up Care With Practitioners Among Medicaid Recipients in Georgia.

Qual Manag Health Care 2021 Sep 24. Epub 2021 Sep 24.

Departments of Market Quality (Drs Yin and Ibe), Quality and Performance Outcomes (Dr Parr), and Behavioral Health (Ms Thompson), CareSource Inc, Atlanta, Georgia; and CareSource Inc, Atlanta, Georgia (Dr Csukas and Mr Jones).

Background And Objectives: It is important that children prescribed attention-deficit/hyperactivity disorder (ADHD) medication get timely follow-up care. In 2018, only 44% of US Medicaid recipients attended a follow-up visit within 30 days of their first ADHD prescription. The objective of this study was to identify the member and practitioner-related predictors that were associated with children who were diagnosed with ADHD and had a follow-up visit within 30 days (initiation phase) of their first prescription of ADHD medication (Index Prescription Start Date, or IPSD). Read More

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September 2021

Spirometry quality predictors in a large multistate prospective study.

Respir Med 2021 Sep 17;188:106618. Epub 2021 Sep 17.

Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA. Electronic address:

Background: The Gulf Long-Term Follow-up (GuLF) Study is a prospective cohort study of health effects associated with oil spill response and clean-up following the 2010 Deepwater Horizon Disaster (DWH). As part of the study, spirometry testing of lung function was carried out in home visits across multiple states. Few studies have described factors associated with spirometry test failure in field-based settings. Read More

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September 2021

NfL predicts relapse-free progression in a longitudinal multiple sclerosis cohort study: Serum NfL predicts relapse-free progression.

EBioMedicine 2021 Sep 24;72:103590. Epub 2021 Sep 24.

Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn(2)), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany. Electronic address:

Background: Easily accessible biomarkers enabling the identification of those patients with multiple sclerosis (MS) who will accumulate irreversible disability in the long term are essential to guide early therapeutic decisions. We here examine the utility of serum neurofilament light chain (sNfL) for forecasting relapse-free disability progression and conversion to secondary progressive MS (SPMS) in the prospective Neurofilamentandlongtermoutcome inMS (NaloMS) cohort.

Methods: The predictive ability of sNfL at Baseline and sNfL follow-up (FU)/ Baseline (BL) ratio with regard to disability progression was assessed within a development cohort (NaloMS, n=196 patients with relapsing-remitting MS (RRMS) or clinically isolated syndrome) and validated with an external independent cohort (Düsseldorf, Essen, n=204). Read More

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September 2021

National trends in testing for hepatitis C virus in licensed opioid treatment programs: Differences by facility ownership and state medicaid expansion status.

Drug Alcohol Depend 2021 Sep 24;228:109092. Epub 2021 Sep 24.

Health Behavior and Health Education, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4301W. Markham, Little Rock, AR 72205, USA; Southern Public Health and Criminal Justice Research Center, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4301W. Markham, Little Rock, AR 72205, USA. Electronic address:

Background: The recent surge in hepatitis C virus (HCV) prevalence is primarily due to increased injection drug use. Opioid treatment programs (OTPs) are a major source of treatment for people at risk for HCV and are ideal settings for on-site HCV testing. The purpose of this national study was to identify state- and facility-level factors associated with HCV testing availability. Read More

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September 2021

The difference between cystatin C- and creatinine-based eGFR is associated with adverse cardiovascular outcome in patients with chronic kidney disease.

Atherosclerosis 2021 Aug 27;335:53-61. Epub 2021 Aug 27.

Yonsei University, Institute of Kidney Disease Research, College of Medicine, Department of Internal Medicine, Seoul, South Korea. Electronic address:

Background And Aims: Decreased kidney function is an important risk factor for cardiovascular disease (CVD). However, assessing risk of CVD may be difficult when there is a gap between creatinine- and cystatin C-based estimated glomerular filtration rate (eGFR). We studied the association of the difference in eGFRs with major adverse cardiovascular events (MACE) in patients with chronic kidney disease (CKD). Read More

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Differential Risk of Fracture Attributable to Type 2 Diabetes Mellitus According to Skeletal Site.

Bone 2021 Sep 24:116220. Epub 2021 Sep 24.

University of Manitoba, Winnipeg, Canada.

Background: Impaired bone quality, especially related to accumulation of advanced glycation end-products (AGEs) and higher incidence of falls contribute substantially to a higher risk of fracture associated with type 2 diabetes mellitus (T2DM). These factors may predispose to fractures more at skeletal sites where impaired bone toughness and falls play a larger pathogenic role (such as hip fractures) compared to skeletal sites where they are less important (such as vertebral fractures).

Objective: To determine if the associations of T2DM with prevalent and incident vertebral fractures are as strong as they are for hip and other non-vertebral fractures. Read More

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September 2021

Trends and Inpatient Outcomes of Primary Atrial Fibrillation Hospitalizations with Underlying Iron Deficiency Anemia: An Analysis of The National Inpatient Sample Database from 2004-2018.

Curr Probl Cardiol 2021 Sep 24:101001. Epub 2021 Sep 24.

Duke Clinical Research Institute and Division of Cardiology, Durham, NC; Duke University Medical Center, Durham, NC.

Atrial fibrillation (AF) is the most prevalent arrhythmia in the United States. However, studies evaluating the impact of iron deficiency anemia on AF outcomes are limited. Therefore, we aimed to evaluate the association of iron deficiency anemia (IDA) on clinical outcomes in patients hospitalized with AF. Read More

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September 2021

Next-Day Discharge vs. Early Discharge After Transcatheter Aortic Valve Replacement: Systematic Review and Meta-Analysis.

Curr Probl Cardiol 2021 Sep 24:100998. Epub 2021 Sep 24.

Lehigh Valley Heart Institute, Lehigh Valley Health Network, Allentown, PA.

Introduction: With the growing utilization of transcatheter aortic valve replacement (TAVR) as an alternative option to surgical valve replacement (SAVR) in patients considered to be suboptimal for surgery, there is a need to explore the possibility of next day discharge (NDD) and its potential outcomes. The aim of our study is to compare outcomes and complications following NDD versus the standard early discharge (ED) (less than three days).

Methods: A comprehensive literature search was performed in PubMed, Embase, and Cochrane to identify relevant trials. Read More

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September 2021

Association between Cirrhosis and 30-day Rehospitalization after Index Hospitalization for Heart Failure.

Curr Probl Cardiol 2021 Sep 24:100993. Epub 2021 Sep 24.

George Washington University School of Medicine, Division of Nephrology, Washington DC, USA.

There are limited data on clinical outcomes in patients re-admitted with decompensated heart failure (HF) with concomitant liver cirrhosis. We conducted a cross sectional analysis of the Nationwide Readmissions Database (NRD) years 2010 thru 2012. An Index admission was defined as a hospitalization for decompensated heart failure among persons aged ≥ 18 years with an alive discharge status. Read More

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September 2021

Rifaximin reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial.

J Hepatol 2021 Sep 24. Epub 2021 Sep 24.

Institute of Liver Studies, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, 125 Coldharbour Lane, London SE5 9NU, UK; Institute of Liver Studies, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK. Electronic address:

Background: Rifaximin is efficacious in the prevention of recurrent hepatic encephalopathy (HE) but its mechanism of action remains unclear. We postulated that rifaximin reduces gut microbiota-derived endotoxemia and systemic inflammation, a known driver of HE.

Design: A randomised placebo-controlled double-blind mechanistic study of rifaximin versus placebo was performed in cirrhotic patients with HE. Read More

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September 2021

Associations Between Intrinsic Capacity and Adverse Events Among Nursing Home Residents: The INCUR Study.

J Am Med Dir Assoc 2021 Sep 24. Epub 2021 Sep 24.

Gerontopole of Toulouse, Institute of Ageing, Toulouse University Hospital (CHU Toulouse), Toulouse, France; CERPOP UMR1295, Université de Toulouse, Inserm, UPS, Toulouse, France.

Objectives: The predictive ability of the novel intrinsic capacity (IC) construct has been scarcely investigated in the nursing home setting. The objective of this study was to investigate the associations of IC and its individual domains with mortality, hospitalization, pneumonia onset, and functional status decline in a population of nursing home residents (NHRs).

Design: We undertook an analysis using data from the INCUR study, a prospective observational study. Read More

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September 2021

Inflammatory Bowel Disease Clinical Activity Is Associated with COVID-19 Severity Especially in Younger Patients.

J Crohns Colitis 2021 Sep 27. Epub 2021 Sep 27.

SickKids IBD Centre, Division of Gastroenterology, Hepatology & Nutrition, The Hospital for Sick Children, and Child Health Evaluative Sciences, SickKids Research Institute, Toronto, ON, Canada.

Background And Aims: Age is a major prognostic factor for COVID-19 outcomes. The effect of IBD activity on COVID-19 is unclear. We examined the relationship between IBD activity and COVID-19 severity according to age. Read More

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September 2021

Social disadvantage and gambling severity: a population-based study with register-linkage.

Eur J Public Health 2021 Sep 27. Epub 2021 Sep 27.

Department of Public Health Solutions, Health and Well-Being Promotion Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.

Background: Studies have found an association between problem gambling and poverty. However, there is relatively little research on social inequalities and problem gambling using population representative data.

Methods: A population-representative self-report web-based and postal survey with register-based linkage was conducted in the three geographical areas of Finland. Read More

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September 2021

Anxiety about dental treatment - a gender issue.

Acta Odontol Latinoam 2021 Aug;34(2):195-200

Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Clínica Odontológica, Rio de Janeiro, Brasil.

This study compared prevalence and risk factors of dental anxiety between men and women. The sample consisted of 244 participants (n = 122 men) aged 18 years or older who sought dental care at a public Dental Education Institution from March 2018 to November 2019. The Modified Dental Anxiety Scale was used to determine presence of dental anxiety. Read More

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Dental fluorosis severity in children 8-12 years old and associated factors.

Acta Odontol Latinoam 2021 Aug;34(2):156-165

Universidade Estadual Paulista, São Paulo, Facultad de Odontologia de Araraquara, Programa de Pos-Graduación em Ciências Odontológicas, Araraquara-SP, Brasil.

The aim of this study was to determine the frequency and severity of dental fluorosis (DF) and the association between severity and risk factors. In a cross-sectional study, 8- to 12-year-old children, born in a Colombian district, were evaluated according to the Thylstrup and Fejerskov Index (TFI) by two calibrated examiners. Molar Incisor Hypomineralization (MIH) and dental caries (DC) were also evaluated. Read More

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Potential considerations in decision making on laparoscopic colorectal resections in Hungary based on administrative data.

PLoS One 2021 27;16(9):e0257811. Epub 2021 Sep 27.

Mental Health Sciences Doctoral School, Semmelweis University, Budapest, Hungary.

Background: Laparoscopic colorectal surgeries offer numerous advantages over their open counterparts. To compare these measurable short-time outcomes of open and laparoscopic resections in Hungary, data of colorectal surgeries were collected and analysed. The study focused on identifying patients' characteristics that can influence the decision on laparoscopic colorectal resections and on comparing efficiency of Hungarian colorectal operations with international data. Read More

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September 2021

Food insecurity status and determinants among Urban Productive Safety Net Program beneficiary households in Addis Ababa, Ethiopia.

PLoS One 2021 27;16(9):e0256634. Epub 2021 Sep 27.

Department of Environmental Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

Background: Measuring household food insecurity in specific geographic areas provides vital information that enables appropriate and effective intervention measures to be taken. To that end, this study aimed to assess the prevalence of food insecurity and associated factors among Urban Productive Safety Net Program (UPSNP) beneficiary households in Addis Ababa, Ethiopia's capital city.

Methods: A community-based cross-sectional study was conducted among 624 UPSNP beneficiary households in nine districts of Addis Ababa from June to July 2019. Read More

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September 2021

Comparison of characteristics and management of emergency department presentations between patients with met and unmet palliative care needs.

PLoS One 2021 27;16(9):e0257501. Epub 2021 Sep 27.

Department of Emergency Medicine, University of Alberta, Edmonton Alberta, Canada.

Introduction: This study examined emergency department (ED) presentations of patients with end of life (EOL) conditions and patients having met and unmet palliative care needs were compared.

Methods: Presentations for EOL conditions were prospectively identified and screened for palliative care needs. Descriptive data were reported as proportions, means or medians. Read More

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September 2021

Married women's decision-making autonomy in the household and maternal and neonatal healthcare utilization and associated factors in Debretabor, northwest Ethiopia.

PLoS One 2021 27;16(9):e0255021. Epub 2021 Sep 27.

UNFPA Supported Maternal Health Project Coordinator, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Women's decision-making autonomy is very crucial for the improvement of women empowerment, and maternal, neonatal, and child healthcare utilization. As time immemorial, Ethiopian culture is largely gender stratified, and the position of women is subordinate to men in various household and health-seeking decision-making matters. However, there is a dearth of empirical evidence on women's decision-making autonomy, especially in the household and on maternal and newborn healthcare utilization. Read More

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September 2021

Body mass index in offspring of mothers with diabetes mellitus: follow-up at 2, 4, 6, and 8 years of age.

Bol Med Hosp Infant Mex 2021 ;78(5):395-403

Laboratorio de Neurofisiología Cognitiva, Instituto Nacional de Rehabilitación. Mexico City, Mexico.

Background: Offspring of mothers with diabetes mellitus (DM) during pregnancy may be at high risk for developmental alterations. This study aimed to identify the effects of maternal pre- and gestational diabetes on the body mass index of infants and children at two, four, six, and eight years of age.

Methods: We studied children of mothers with type 1, type 2, and gestational diabetes and a control group. Read More

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January 2021

The Association of Bullous Pemphigoid With Atopic Dermatitis and Allergic Rhinitis-A Population-Based Study.

Dermatitis 2021 Sep 27. Epub 2021 Sep 27.

From the Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany Azrieli Faculty of Medicine, Bar-Ilan University, Safed Unit of Dermatology, Baruch Padeh Poria Medical Center, Tiberias Clalit Health Services, Tel-Aviv Siaal Research Center for Family Medicine and Primary Care, Faculty of Health Sciences Otolaryngology Department, Barzilai University Medical Center, Ben-Gurion University of the Negev, Beer Sheva Department of Behavioral Sciences, Ariel University Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Background: Although bullous pemphigoid (BP), atopic dermatitis (AD), and allergic rhinitis (AR) are associated with shared pathogenic mechanisms the epidemiological relationship between these conditions remains to be investigated.

Objective: To evaluate the bidirectional association of BP with AD and AR.

Methods: A population-based retrospective cohort study was performed comparing BP patients (n = 3924) with age-, sex-, and ethnicity-matched control subjects (n = 19,280), with respect to incident cases of AD and AR. Read More

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September 2021

Hearing Loss After Radiation and Chemotherapy for CNS and Head-and-Neck Tumors in Children.

J Clin Oncol 2021 Sep 27:JCO2100899. Epub 2021 Sep 27.

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.

Purpose: Hearing loss (HL) is a serious secondary effect of treatment for CNS and head-and-neck tumors in children. The goal of this study was to evaluate incidence and risk factors for HL in patients with multiple ototoxic exposures.

Patients And Methods: We evaluated 340 ears from 171 patients with CNS or head-and-neck tumors treated with radiation, with or without chemotherapy, who had longitudinal audiologic evaluation. Read More

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September 2021

Depression associated with APOE status and hippocampal volume but not cognitive decline in older adults aging with traumatic brain injury.

Neuropsychology 2021 Sep 27. Epub 2021 Sep 27.

Department of Psychology.

Objective: To examine the relationship between depression and cognition, genetic risk, and hippocampal differences in a sample of older adults with a history of traumatic brain injury (TBI).

Method: Participants were 85 males and 35 females (91 Caucasian, 29 African-American) with a mean age of 65.04 (±8. Read More

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September 2021

Early onset of deep sternal wound infection after cardiac surgery is associated with decreased survival: A propensity weighted analysis.

J Card Surg 2021 Sep 27. Epub 2021 Sep 27.

Department of Cardiothoracic Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, California, USA.

Objectives: To compare outcomes after the development of early (≤30 days) versus delayed (>30 days) deep sternal wound infection (DSWI) after cardiac surgery.

Methods: Between 2005 and 2016, 64 patients were treated surgically for DSWI following cardiac surgery. Thirty-three developed early DSWI, while 31 developed late DSWI. Read More

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September 2021

Association Between Iodine Nutritional Status and Adverse Pregnancy Outcomes in Beijing, China: a Single-Center Cohort Study.

Biol Trace Elem Res 2021 Sep 27. Epub 2021 Sep 27.

Department of Endocrinology, Peking University People's Hospital, Beijing, 100044, China.

Iodine is an essential trace element for humans and the main raw material for thyroid hormone synthesis. However, the association between iodine nutritional status and adverse pregnancy outcomes in different regions remains controversial. This single-center cohort study was focused on the association between iodine nutritional status and adverse pregnancy outcomes in Beijing, China. Read More

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September 2021

Identifying Modifiable and Non-modifiable Risk Factors of Readmission and Short-Term Mortality in Chondrosarcoma: A National Cancer Database Study.

Ann Surg Oncol 2021 Sep 27. Epub 2021 Sep 27.

Department of Orthopaedic Surgery, Duke University Hospital, Durham, NC, USA.

Background: Limited data are available to inform the risk of readmission and short-term mortality in musculoskeletal oncology. The goal of this study was to identify factors independently associated with 30-day readmission and 90-day mortality following surgical resection of chondrosarcoma.

Methods: We retrospectively reviewed 6653 patients following surgical resection of primary chondrosarcoma in the National Cancer Database (2004-2017). Read More

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September 2021

Associations between ambient fine particulate (PM) exposure and cardiovascular disease: findings from the China Health and Retirement Longitudinal Study (CHARLS).

Environ Sci Pollut Res Int 2021 Sep 27. Epub 2021 Sep 27.

Department of Emergency, Panyu Central Hospital, No. 8, Fuyu East Road, Panyu District, Guangzhou, 510006, Guangdong Province, China.

The evidence regarding the association between long-term fine particulate (PM) exposure and cardiovascular disease (CVD) in developing countries is limited. This study investigated the association between long-term exposure to PM and the prevalence of CVD among middle-aged and older adults. A total of 13,484 adults ≥ 45 years of age were surveyed in China, and logistic regression models were used to examine the association between PM and the prevalence of CVD. Read More

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September 2021

Seasonal Variation In Management And Outcomes Of Cardiac Arrest Complicating Acute Myocardial Infarction.

QJM 2021 Sep 27. Epub 2021 Sep 27.

Section of Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

Background: There are limited data on the influence of seasons on the outcomes of acute myocardial infarction-cardiac arrest (AMI-CA).

Methods: Using the National Inpatient Sample from 2000-2017, adult (>18 years) admissions with AMI-CA were identified. Seasons were defined by the month of admission as spring, summer, fall, and winter. Read More

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September 2021

Clinical and Demographic Factors Associated With Diabetic Retinopathy Among Young Patients With Diabetes.

JAMA Netw Open 2021 Sep 1;4(9):e2126126. Epub 2021 Sep 1.

Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison.

Importance: Diabetic retinopathy (DR) is a leading cause of vision loss worldwide. As the incidence of both type 1 and type 2 diabetes among youths continues to increase around the world, understanding the factors associated with the development of DR in this age group is important.

Objective: To identify factors associated with DR among children, adolescents, and young adults with type 1 or type 2 diabetes in the US. Read More

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September 2021