18,802 results match your criteria october 2016


Revisiting the epidemiology of bloodstream infections and healthcare-associated episodes. Results from a multicentre prospective cohort in Spain (PRO-BAC study).

Int J Antimicrob Agents 2021 May 4:106352. Epub 2021 May 4.

Unidad Clínica de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospital Universitario Virgen Macarena / Departamento de Medicina, Universidad de Sevilla / Instituto de Biomedicina de Sevilla, Sevilla, Spain.

Background: The epidemiology of bloodstream infections (BSI) is dynamic because it depends on microbiological, host, and healthcare system factors. The aim of this study is to update the information about the epidemiology of BSI in Spain considering the types of acquisition.

Methods: An observational, prospective cohort study in 26 Spanish hospitals from October 2016 throughout March 2017 including all episodes of BSI in adults was performed. Read More

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BPV associated with imaging features of SSI on MRI.

Brain Behav 2021 May 7:e02155. Epub 2021 May 7.

Department of Neurology, Weihai Central Hospital Affiliated to Qingdao University, Weihai, China.

Objectives: A retrospective study was performed to investigate the relationship between blood pressure variability (BPV) and imaging features of single small infarction (SSI) on magnetic resonance imaging (MRI).

Materials And Methods: Two hundreds and five patients with SSI and 120 healthy subjects matched with age and sex as the control group were enrolled into this study. All subjects came from the Affiliated Hospital to Qingdao University and Qingdao Municipal Hospital from October 2011 to June 2016. Read More

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Timing of bleeding and thromboembolism associated with endoscopic submucosal dissection for gastric cancer in Japan.

J Gastroenterol Hepatol 2021 May 7. Epub 2021 May 7.

Department of Gastroenterology, Kanazawa University Hospital.

Objective: This study aimed to reveal the timing of bleeding and thromboembolism associated with endoscopic submucosal dissection (ESD) for early gastric cancer (EGC).

Methods: We retrospectively reviewed 10,320 patients who underwent ESD for EGC during November 2013-October 2016. We evaluated overall bleeding rates and their inter-group differences. Read More

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3T DCE-MRI Radiomics Improves Predictive Models of Complete Response to Neoadjuvant Chemotherapy in Breast Cancer.

Front Oncol 2021 20;11:630780. Epub 2021 Apr 20.

Medical Physics Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

Objectives: To test whether 3T MRI radiomics of breast malignant lesions improves the performance of predictive models of complete response to neoadjuvant chemotherapy when added to other clinical, histological and radiological information.

Methods: Women who consecutively had pre-neoadjuvant chemotherapy (NAC) 3T DCE-MRI between January 2016 and October 2019 were retrospectively included in the study. 18F-FDG PET-CT and histological information obtained through lesion biopsy were also available. Read More

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The Impact of Endograft Selection on Outcomes Following Treatment Outside of Instructions for Use (IFU) in Endovascular Abdominal Aortic Aneurysm Repair (EVAR).

Cureus 2021 May 4;13(5):e14841. Epub 2021 May 4.

Vascular and Endovascular Surgery, University of Western Australia, Perth, AUS.

Background Endovascular aneurysm repair (EVAR) has become the treatment modality of choice in patients with abdominal aortic aneurysms. This has resulted in endograft utilization within instructions for use (IFU) and in cases with proximal neck anatomy outside of IFU. Purpose To identify whether graft selection influences outcomes following EVAR outside of IFU. Read More

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Evidence for self-sustaining populations of Arcuatula senhousia in the UK and a review of this species' potential impacts within Europe.

Sci Rep 2021 May 6;11(1):9678. Epub 2021 May 6.

Institute of Marine Sciences, School of Biological Sciences, University of Portsmouth, Ferry Road, Portsmouth, PO4 9LY, UK.

The invasive Asian date mussel (Arcuatula senhousia) inhabits diverse global coastal environments, in some circumstances posing significant ecological and economic risks. Recently recorded in the Greater North Sea ecoregion, an established population has not previously been confirmed. Combining historical and field data, we provided baseline information from the UK and recorded colonisation in a variety of habitats. Read More

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Development and validation of a score to assess complexity of general internal medicine patients at hospital discharge: a prospective cohort study.

BMJ Open 2021 May 6;11(5):e041205. Epub 2021 May 6.

Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Objective: We aimed to develop and validate a score to assess inpatient complexity and compare its performance with two currently used but not validated tools to estimate complexity (ie, Charlson Comorbidity Index (CCI), patient clinical complexity level (PCCL)).

Methods: Consecutive patients discharged from the department of medicine of a tertiary care hospital were prospectively included into a derivation cohort from 1 October 2016 to 16 February 2017 (n=1407), and a temporal validation cohort from 17 February 2017 to 31 March 2017 (n=482). The physician in charge assessed complexity. Read More

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Assessment of some key indicators of the ecological status of an African freshwater lagoon (Lagoon Aghien, Ivory Coast).

PLoS One 2021 6;16(5):e0251065. Epub 2021 May 6.

Institut Pasteur d'Abidjan, Abidjan, Côte d'Ivoire.

The supply of drinking water is a vital challenge for the people who live on the African continent, as this continent is experiencing strong demographic growth and therefore increasing water demands. To meet these needs, surface water resources are becoming increasingly mobilized because underground resources are not always available or have already been overexploited. This situation is the case in the region of Abidjan in the Ivory Coast, where the drinking water deficit is a growing problem and it is therefore necessary to mobilize new water resources to ensure the supply of drinking water. Read More

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Variability and Costs of Low-Value Preoperative Testing for Cataract Surgery Within the Veterans Health Administration.

JAMA Netw Open 2021 May 3;4(5):e217470. Epub 2021 May 3.

Center for Innovation to Implementation, VA Palo Alto Healthcare System, Palo Alto, California.

Importance: The Choosing Wisely guidelines indicate that preoperative testing is often unnecessary and wasteful for patients undergoing cataract operations. However, little is known about the impact of these widely disseminated guidelines within the US Veterans Health Administration (VHA) system.

Objective: To examine the extent, variability, associated factors, and costs of low-value tests (LVTs) prior to cataract operations in the VHA. Read More

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Evaluation of a Pharmacy-Driven Calcitonin Protocol for Treating Hypercalcemia in Hospitalized Patients: A Multisite Study.

J Pharm Pract 2021 May 6:8971900211013187. Epub 2021 May 6.

Department of Pharmacy, Health First Holmes Regional Medical Center, Melbourne, FL, USA.

Background: The dramatic increase in the acquisition cost of injectable calcitonin led to creating a pharmacy-driven calcitonin protocol to improve the appropriate use of calcitonin and other treatment modalities for hypercalcemia.

Objective: This study aimed to characterize the use of calcitonin before and after implementation of a pharmacy-driven calcitonin protocol.

Methods: This was a multi-center, retrospective study of the use of injectable calcitonin in adult hospitalized patients with hypercalcemia. Read More

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Adequacy of small biopsy and cytology specimens for comprehensive genomic profiling of patients with non-small-cell lung cancer to determine eligibility for immune checkpoint inhibitor and targeted therapy.

J Clin Pathol 2021 May 5. Epub 2021 May 5.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Aims: In advanced-stage non-small-cell lung cancer (NSCLC), incomplete genotyping for guideline-recommended genomic biomarkers poses a significant challenge to making informed and timely clinical decisions. We report our institution's experience in assessing the adequacy of small specimens for comprehensive genomic profiling for guideline-recommended lung cancer biomarker testing.

Methods: We performed a retrospective evaluation of all image-guided procedures for NSCLC performed in our institution between October 2016 and July 2018, including core needle biopsy (CNB) and fine-needle aspiration (FNA) in patients who had undergone genomic profiling for lung cancer. Read More

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Diversifying the health workforce: a mixed methods analysis of an employment integration strategy.

Hum Resour Health 2021 05 5;19(1):62. Epub 2021 May 5.

School of Nursing, McMaster University, 1280 Main Street West, MDCL 3500, Hamilton, ON, L8S 4K1, Canada.

Background: Historically, immigration has been a significant population driver in Canada. In October 2020, immigration targets were raised to an unprecedented level to support economic recovery in response to COVID-19. In addition to the economic impact on Canada, the pandemic has created extraordinary challenges for the health sector and heightened the demand for healthcare professionals. Read More

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Influence Factors of Sexual Intercourse Frequency in Infertile Couples without Sexual Dysfunction in Southwest China: A Retrospective Study.

Urol Int 2021 May 5:1-7. Epub 2021 May 5.

Department of Assisted Reproduction Center, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Introduction: The aim of this study was to investigate the sexual intercourse frequency (SIF) of infertile couples without sexual dysfunction and analyze its related influencing factors.

Materials And Methods: We retrospectively analyzed the data of a total number of 4,923 infertile couples without sexual dysfunction who received treatment in our assisted reproductive center from October 2016 to October 2018. Both partners of couples were inquired about their information of demographic statistics, occupations, lifestyles, education backgrounds, psychological characteristics, and testostrone levels of male patients. Read More

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Estimating the economic cost of nurse sensitive adverse events amongst patients in medical and surgical settings.

J Adv Nurs 2021 May 5. Epub 2021 May 5.

School of Nursing and Midwifery, University College Cork, Cork, Ireland.

Aims: To identify the costs associated with nurse sensitive adverse events and the impact of these events on patients' length of stay.

Design: Retrospective cohort study using administrative hospital data.

Methods: Data were sourced from patient discharge information (N = 5544) from six acute wards within three hospitals (July 2016-October 2017). Read More

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What influences uptake and early adherence to Option B+ (lifelong antiretroviral therapy among HIV positive pregnant and breastfeeding women) in Central Uganda? A mixed methods study.

PLoS One 2021 5;16(5):e0251181. Epub 2021 May 5.

Department of Disease Control and Environmental Health, School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.

Background: High uptake and optimal adherence to Option B+ antiretroviral therapy (ART) increase effectiveness in averting mother-to-child transmission of HIV. Option B+ ART uptake, early adherence, and associated factors need to be evaluated in Central Uganda.

Methods: A mixed approaches study was carried out in six health facilities in Masaka, Mityana, and Luwero districts from October 2013 to February 2016. Read More

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Decomposition of leaf litter in the Brazilian savanna on limestone and sandstone Neosols.

An Acad Bras Cienc 2021 30;93(3):e20200372. Epub 2021 Apr 30.

Programa de Pós-Graduação em Ecologia e Conservação de Recursos Naturais, Universidade Federal de Uberlândia, Instituto de Biologia, Rua João Naves de Ávila, 2121, Umuarama, 38405-320 Uberlândia, MG, Brazil.

Litter decomposition in the soil is an important stage of the nutrient cycling process that interferes with functioning of terrestrial ecosystems. Soil fertility and litter nutritional quality are fundamental factors that affect decomposition efficiency of plant residues. We evaluated decomposition in two areas of 'cerrado sensu stricto', each with a type of Neosol - limestone (eutrophic) and sandstone (dystrophic). Read More

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Impact of Advising on Total Worker Health Implementation.

J Occup Environ Med 2021 Apr 3. Epub 2021 Apr 3.

Center for Health, Work & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, 13001 E. 17 Pl., W-3111, Mail Stop B119 HSC, Aurora, CO 80045 (Tenney, Dexter, Shapiro, Dally, Brown, Schwatka, Newman), Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, 13001 E. 17 Pl., 3 Floor, Mail Stop B119 HSC, Aurora, CO 80045 (Tenney, Dally, Schwatka, Newman), University of Colorado School of Medicine, Adult & Child Consortium for Outcomes Research and Delivery Science (ACCORDS) Dissemination and Implementation program, Division of General Internal Medicine and Center for Women's Health Research, Anschutz Medical Campus, 12631 E. 17th Ave., Mailstop B180, Aurora, CO 80045 (Huebschmann), Principle, Workers Comp Advising LLC (McMillen), Department of Epidemiology, Colorado School of Public Health, and Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, 13001 E. 17 Pl., 3 Floor, Mail Stop B119 HSC, Aurora, CO 80045 (Newman), Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, School of Medicine, University of Colorado Anschutz Medical Campus, 13001 E. 17 Place, Mailstop B119, Aurora, CO, 80045 (Newman).

Objective: Little is understood about the mechanisms for improving the adoption and implementation of Total Worker Health® (TWH) in workplace settings. The primary objective of this study was to identify whether the delivery of TWH advising is associated with subsequent changes in TWH in small-to-medium sized businesses.

Methods: We conducted a longitudinal study of a TWH intervention in 200 organizations completing Health Links Healthy Workplace Assessments™ between October 2016 and December 2019. Read More

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Detection and characterization of carbapenem resistant Gram-negative bacilli isolates recovered from hospitalized patients at Soba University Hospital, Sudan.

BMC Microbiol 2021 May 4;21(1):136. Epub 2021 May 4.

Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.

Background: Antimicrobial resistance (AMR) poses a complex threat to global health security and universal health coverage. Recently, nosocomial infections with carbapenemase-producing Gram-negative bacilli (GNB) is increasing worldwide. We report the molecular characterization and detection of genes associated with carbapenemase producing Gram negative bacteria isolated from hospitalized patients at Soba University Hospital (SUH) in Khartoum State, Sudan. Read More

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Distribution of Pathogen Resources by the National Culture Collection for Pathogens in South Korea from 2015 to 2019.

Biopreserv Biobank 2021 May 4. Epub 2021 May 4.

Division of Pathogen Resource Management, Center for Public Vaccine Development and Support, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju-si, South Korea.

The National Culture Collection for Pathogens (NCCP) in the Korea Disease Control and Prevention Agency (KDCA) is in charge of the collection, quality control, and commercialization of pathogens and of information on pathogens that cause infectious diseases, and distributes them to be utilized for promoting public health and the health care industry. Since the NCCP Task Force was established in 2009 and the law for collection, management, and exploitation of pathogen resources became effective in 2017, NCCP has been responsible for the deposition, registration, and preservation of pathogen resources. Herein, we provide information on the recent status of pathogen resource distribution over the past 5 years and pathogen resources that are available for distribution presently. Read More

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Health seeking behaviour among Lebanese population: A highlight on seeking care from pharmacists.

Eur J Gen Pract 2021 Dec;27(1):51-59

Faculty of Medicine, Beirut Arab University, Beirut, Lebanon.

Background: Understanding health-seeking behaviour could significantly reduce the impact of illness on patients' lives. Fragmentation of the Lebanese healthcare system and presence of variability in socio-economic factors have affected some aspects of the Lebanese population's overall health seeking behaviour. One of these aspects is seeking diagnosis from pharmacists, which is prohibited by the Lebanese law but reinforced by the absence of supervision of concerned authorities. Read More

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December 2021

Single-dose amikacin plus 7 days of amoxicillin/clavulanate to treat acute cystitis caused by extended-spectrum beta-lactamase-producing : A retrospective cohort study.

Investig Clin Urol 2021 May;62(3):310-316

Department of Urology, Korea University Guro Hospital, Seoul, Korea.

Purpose: Treatment options for urinary tract infection (UTI) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms are limited other than carbapenem. Accordingly, clinicians should investigate alternative antimicrobial options for limited infection. This study was performed to assess the efficacy of single-dose amikacin and a 7-day oral regimen of amoxicillin/clavulanate for the treatment of acute cystitis caused by ESBL-producing and . Read More

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Is there a role for doravirine in African HIV treatment programmes? A large observational resistance study in South Africa.

J Int AIDS Soc 2021 May;24(5):e25706

Department of Molecular Medicine and Haematology, National Health Laboratory Services, Johannesburg, South Africa.

Introduction: Dolutegravir has replaced efavirenz in most low- and middle-income countries, due to better tolerability and formidable resistance profile, but dolutegravir side effects suggest alternatives are needed. We evaluated doravirine resistance in South Africa as a first step to assess whether doravirine may replace dolutegravir.

Methods: A retrospective dataset was analysed for predicted doravirine susceptibility, including sequences obtained from three patient groups. Read More

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Quality assurance audit in adult cardiac anaesthesia.

J Pak Med Assoc 2021 Feb;71(2(B)):704-707

Department of Anaesthesia, Tabba Heart Institute, Karachi, Pakistan.

Objective: To assess different anaesthesia-related quality indicators during adult cardiac surgery.

Methods: The prospective clinical audit was conducted at the Aga Khan University Hospital, Karachi, from October 2016 to March 2017, and comprised all adult patients scheduled for cardiac surgery. Different anaesthesia-related quality indicators were observed during the pre-induction phase, before the cardiopulmonary bypass, during the procedure, and post-surgery till the transfer from the operating room to the cardiac intensive care unit. Read More

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February 2021

Associations of perfluorooctane sulfonate alternatives and serum lipids in Chinese adults.

Environ Int 2021 Apr 30;155:106596. Epub 2021 Apr 30.

Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. Electronic address:

Background: Chlorinated polyfluorinated ether sulfonic acids (Cl-PFESAs), a group of perfluorooctane sulfonate (PFOS) alternatives, can be widely observed in humans and environmental matrices. However, associations between exposure to Cl-PFESAs and serum lipid levels in adults are unknown.

Objective: To explore the relationships between Cl-PFESA levels and serum lipid levels in adults. Read More

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Association of Local Variation in Neighborhood Disadvantage in Metropolitan Areas With Youth Neurocognition and Brain Structure.

JAMA Pediatr 2021 May 3:e210426. Epub 2021 May 3.

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles.

Importance: Neighborhood disadvantage is an important social determinant of health in childhood and adolescence. Less is known about the association of neighborhood disadvantage with youth neurocognition and brain structure, and particularly whether associations are similar across metropolitan areas and are attributed to local differences in disadvantage.

Objective: To test whether neighborhood disadvantage is associated with youth neurocognitive performance and with global and regional measures of brain structure after adjusting for family socioeconomic status and perceptions of neighborhood characteristics, and to assess whether these associations (1) are pervasive or limited, (2) vary across metropolitan areas, and (3) are attributed to local variation in disadvantage within metropolitan areas. Read More

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Gender Minority Stress, Support, and Inflammation in Transgender and Gender-Nonconforming Youth.

Transgend Health 2021 Apr 16;6(2):91-100. Epub 2021 Apr 16.

Department of Pediatrics, Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.

Transgender and gender-nonconforming (TGNC) youth often report higher rates of chronic social stressors such as victimization, discrimination, and rejection. Some of these gender-based stressors may have long-range physical health consequences through inflammation pathways. This study evaluates the feasibility and acceptability of adding biological measures of inflammation to an ongoing prospective clinical study of TGNC youth (ages 9-20 years), initiating affirming medical therapy at a large, urban children's hospital (=56). Read More

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Various Neurological Symptoms with Vitamin B12 Deficiency and Posttreatment Evaluation.

J Pediatr Neurosci 2020 Oct-Dec;15(4):365-369. Epub 2021 Jan 19.

Department of Pediatric Neurology, Izmir Katip Celebi University, Izmir, Turkey.

Background: Vitamin B12 deficiency occurs primarily as a result of insufficient dietary intake in children in developing countries. Vitamin B12 deficiency produces a cluster of neurological symptoms in children.

Aim: The aim of this study was to describe the vitamin B12 status of patients who were admitted with neurological symptoms and to evaluate the clinical response to vitamin B12 treatment. Read More

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January 2021

Early Orthostatic Exercise by Head-Up Tilt With Stepping vs. Standard Care After Severe Traumatic Brain Injury Is Feasible.

Front Neurol 2021 14;12:626014. Epub 2021 Apr 14.

Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

Intensive rehabilitation of patients after severe traumatic brain injury aims to improve functional outcome. The effect of initiating rehabilitation in the early phase, in the form of head-up mobilization, is unclear. To assess whether early mobilization is feasible and safe in patients with traumatic brain injury admitted to a neurointensive care unit. Read More

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MRI Spectrum of Japanese Encephalitis in Northeast India: A Cross-Sectional Study.

J Neurosci Rural Pract 2021 Apr 24;12(2):281-289. Epub 2021 Mar 24.

Department of Radiodiagnosis, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.

 Japanese encephalitis (JE) is an arthropod-borne flavivirus infection having high mortality and morbidity. This study was performed to evaluate the conventional magnetic resonance imaging (MRI) findings in JE and to find out any difference between pediatric and adult JE.  This retrospective study was performed on serologically positive 54 JE patients presented to a tertiary care hospital with acute encephalitic symptoms between April 2016 and October 2019. Read More

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Addition of computed tomography chest increases the diagnosis rate in patients with suspected intestinal tuberculosis.

Intest Res 2021 May 4. Epub 2021 May 4.

Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.

Background/aims: Intestinal tuberculosis (ITB) is difficult to diagnose due to poor sensitivity of definitive diagnostic tests. ITB may be associated with concomitant pulmonary tuberculosis (PTB) which may remain undetected on chest X-ray. We assessed the role of contrast enhanced computed tomography (CECT) chest in detecting the prevalence of active PTB, and increasing the diagnostic yield in patients with suspected ITB. Read More

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