250,501 results match your criteria observed period


Radiation Exposure in the Neonatal Intensive Care Unit in Newborns and Staff.

Am J Perinatol 2021 Jul 28. Epub 2021 Jul 28.

Department of Radiology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

Objective:  Portable X-rays remain one of the most frequently used diagnostic procedures in neonatal intensive care units (NICU). Premature infants are more sensitive to radiation-induced harmful effects. Dangers from diagnostic radiation can occur with stochastic effects. Read More

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Genetic continuity of Bronze Age ancestry with increased Steppe-related ancestry in Late Iron Age Uzbekistan.

Mol Biol Evol 2021 Jul 28. Epub 2021 Jul 28.

Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing, 100044, China.

While Uzbekistan and Central Asia are known for the well-studied Bronze Age civilization of Bactria-Margiana Archaeological Complex (BMAC), the lesser-known Iron Age was also a dynamic period that resulted in increased interaction and admixture among different cultures from this region. To broaden our understanding of events which impacted the demography and population structure of this region, we generated 27 genome-wide SNP capture datasets of Late Iron Age individuals around the Historical Kushan time period (∼2100-1500 BP) from three sites in South Uzbekistan. Overall, Bronze Age ancestry persists into the Iron Age in Uzbekistan, with no major replacements of populations with Steppe-related ancestry. Read More

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Plasma progesterone secretion during gestation of the captive short-beaked echidna.

Reproduction 2021 Jul 1. Epub 2021 Jul 1.

S Johnston, School of Agriculture and Food Science, The University of Queensland, Gatton, Australia.

This study describes the progesterone profile during pregnancy in sexually mature female captive short-beaked echidnas (Tachyglossus aculeatus aculeatus). Echidnas were monitored daily by video surveillance to confirm key reproductive behaviour. Plasma samples were collected and pouch morphology assessed three times a week. Read More

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Safety and Reactogenicity of the ChAdOx1 (AZD1222) COVID-19 vaccine in Vaccinee in Saudi Arabia.

Int J Infect Dis 2021 Jul 25. Epub 2021 Jul 25.

Specialty Internal Medicine and Quality Department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Infectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN (USA); Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

Introduction: The Kingdom of Saudi Arabia was one of the first countries to implement a COVID-19 vaccination program. Here, we estimated the safety and reactogenicity of the ChAdOx1-S vaccine as administered to adults after the first dose.

Methods: This is a cross-sectional study and included 1592 randomly selected vaccinees from April to May, 2021. Read More

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Expression and prognostic significance of vascular endothelial growth factor-A (VEGF-A) and its receptor in canine prostate cancer.

Prostate 2021 Jul 28. Epub 2021 Jul 28.

Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu, Sao Paulo, Brazil.

Background: Vascular endothelial growth factor-A (VEGF-A) and its receptor, VEGF receptor-2 (VEGFR-2), represent a complex family of angiogenic molecules consisting of different ligands and receptors. Due to the importance of VEGF-A/VEGFR-2 signaling in tumor proliferation and angiogenesis, this study aimed to evaluate the protein and gene expression levels of VEGF-A and VEGFR-2 in canine prostate cancer (PC).

Methods: We analyzed VEGF-A and VEGFR-2 expression in 87 PC samples by immunohistochemistry and quantitative-polymerase chain reaction. Read More

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Treatment and posttreatment effects of Herbst appliance therapy on trabecular structure of the mandible using fractal dimension analysis.

Eur J Orthod 2021 Jul 28. Epub 2021 Jul 28.

Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.

Objectives: This controlled study aimed to evaluate the effects of Herbst therapy on the trabecular structure of the condyle and angulus mandible using fractal dimension analysis (FD-A) accompanied by skeletal cephalometric changes.

Material And Method: The panoramic and cephalometric radiographs of 30 patients with skeletal Class II malocclusion treated with the Herbst appliance (C II-H group, mean age: 15.23 ± 1. Read More

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Temporal Trend of Mortality Due to Ischemic Heart Diseases in Northeastern Brazil (1996-2016): An Analysis According to Gender and Age Group.

Arq Bras Cardiol 2021 Jul;117(1):51-60

Universidade Federal de Alagoas, Maceió, AL - Brasil.

Background: Ischemic heart disease (IHD) is the leading cause of death among cardiovascular diseases (CVD).

Objective: To describe the sociodemographic profile and analyze the trend in the mortality rate due to IHD, according to sex and by age group, in the states of the Northeast region of Brazil, from 1996 to 2016.

Methods: Ecological study involving IHD mortality in the northeastern states. Read More

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Stable fly activity is associated with dairy management practices and seasonal weather conditions.

PLoS One 2021 28;16(7):e0253946. Epub 2021 Jul 28.

Veterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California Davis, Tulare, California, United States of America.

Stable flies (Stomoxys calcitrans) are blood-sucking insects commonly associated with cattle production systems worldwide and are known to cause severe irritation to cattle due to painful bites. Cattle react to biting stable flies with an aggregating behavior known as bunching. Bunching behavior reduces grazing or feed consumption and thus reduces cattle productivity and welfare. Read More

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Buried Bumper Syndrome: Early or Late?

Gastroenterol Nurs 2021 Jul 27. Epub 2021 Jul 27.

Şehmus Ölmez, MD, is Associate Professor, Department of Gastroenterology, Health Sciences University, Adana City Training & Research Hospital, Adana, Turkey. Bünyamin Sarıtaş, MD, is Specialist, Health Sciences University, Adana City Training & Research Hospital, Adana, Turkey. Mehmet Suat Yalçın, MD, is Associate Professor, Department of Gastroenterology, Aksaray University, Aksaray, Turkey. Nevin Akçaer Öztürk, MD, is Associate Professor, Department of Gastroenterology, Health Sciences University, Adana City Training & Research Hospital, Adana, Turkey. Adnan Taş, MD, is Associate Professor, Department of Gastroenterology, Health Sciences University, Adana City Training & Research Hospital, Adana, Turkey. Banu Kara, MD, is Associate Professor, Department of Gastroenterology, Health Sciences University, Adana City Training & Research Hospital, Adana, Turkey.

Buried bumper syndrome (BBS) is a rare and serious complication of percutaneous endoscopic gastrostomy (PEG) tube placement. In the literature, BBS is considered to be a late complication of PEG procedure, but it may occur in the early period after PEG tube placement. Early diagnosis and proper treatment are important. Read More

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Induction Therapy With Antithymocyte Globulin and Delayed Calcineurin Inhibitor Initiation for Renal Protection in Liver Transplantation: A Multicenter Randomized Controlled Phase II-B Trial.

Transplantation 2021 Jul 27. Epub 2021 Jul 27.

Digestive Disease and Surgery Institute, Transplant Center, Cleveland Clinic, Cleveland, OH. Division of Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH. Transplant Center, Cleveland Clinic Weston, Weston, FL. Division of Transplantation Surgery, Medical College of Wisconsin, Milwaukee, WI. Transplantation Institute, University of Chicago Medicine, Chicago, IL.

Background: Calcineurin inhibitor (CNI) based immunosuppression in liver transplantation (LTx) is associated with acute and chronic deterioration of kidney function. Delaying CNI initiation by using induction rabbit anti-thymocyte globulin (rATG) may provide kidneys with adequate time to recover from a perioperative insult reducing the risk of early post-LTx renal deterioration.

Methods: This was an open-label, multicenter, randomized controlled clinical trial comparing use of induction rATG with delayed CNI initiation (day-10) against upfront CNI commencement (SOC; standard of care) in those patients deemed at standard risk of postoperative renal dysfunction following LTx. Read More

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First Report of Lotus Seedpod Withering Caused by Fusarium proliferatum on Nelumbo nucifera Plants in China.

Plant Dis 2021 Jul 28. Epub 2021 Jul 28.

Jiangxi Agricultural University, 91595, College of Agronomy, Zhimin Road, Nanchang, China, 330045;

Nelumbo nucifera (Nymphaeaceae family) is a well-known plant in China and with the increasing value of this crop, the planting area of lotus is expanding. In May 2019, an unknown withering lotus seedpod was obtained in Guangchang County of Jiangxi Province (26.79°N, 116. Read More

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A Giant Diving Ranula Extending to the Skull Base in Pediatric Age.

J Craniofac Surg 2021 Jul-Aug 01;32(5):e515-e517

Department of Oto-Rhino-Laryngology and Head and Neck Surgery, Faculty of Medicine, Suleyman Demirel University.

Abstract: Ranula is a retention cyst that develops from the salivary glands. It has 2 subtypes, oral and diving. There are differences in the clinical features of ranula subtypes. Read More

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Robust joint modelling of longitudinal and survival data: Incorporating a time-varying degrees-of-freedom parameter.

Biom J 2021 Jul 28. Epub 2021 Jul 28.

Department of Statistics, Lund University, Lund, Sweden.

Monitoring of individual biomarkers has the potential of explaining the hazard of survival outcomes. In practice, these measurements are intermittently observed and are known to be subject to substantial measurement error. Joint modelling of longitudinal and survival data enables us to associate intermittently measured error-prone biomarkers with risks of survival outcomes and thus plays an important role in the analysis of medical data. Read More

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Clinical experience on umbilical cord mesenchymal stem cell treatment in 210 severe and critical COVID-19 cases in Turkey.

Stem Cell Rev Rep 2021 Jul 28. Epub 2021 Jul 28.

Geneis, Genetic System Solutions, İstanbul, Turkey.

Objective: Treatment for COVID-19 is still urgent need for the critically ill and severe cases. UC-MSC administration has a therapeutic benefit for severe COVID-19 patients even in the recovery period. In this paper, we aimed to present our clinical experience with UC-MSC treatment in severe and critical severe COVID-19 patients. Read More

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Long-term outcome of ventricular tachycardia ablation in patients who did not undergo programmed electrical stimulation after ablation.

J Interv Card Electrophysiol 2021 Jul 28. Epub 2021 Jul 28.

Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, 2 - 34 - 10 Ebisu, Shibuya-ku, Tokyo, Japan.

Background: Ventricular arrhythmia inducibility is one of the ideal endpoints of ventricular tachycardia (VT) ablation. However, it may be challenging to implement programmed electrical stimulation (PES) at the end of the procedure under several circumstances. The long-term outcome of patients who did not undergo PES after VT ablation remains largely unknown. Read More

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Improvement in Breast Reconstruction Disparities following Medicaid Expansion under the Affordable Care Act.

Ann Surg Oncol 2021 Jul 28. Epub 2021 Jul 28.

Loma Linda University Health, Loma Linda, CA, USA.

Background:  Under the Affordable Care Act, Medicaid expansion effective 1 January 2014 aimed to increase access to health care. We sought to determine the association of Medicaid expansion with disparities in utilization of breast reconstruction.

Methods: Non-Hispanic Black (NHB) and White (NHW) breast cancer patients undergoing mastectomy +/- reconstruction between 2010 and 2017 were selected from the National Cancer Database. Read More

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Contemporaneous Comparison of Outcomes Among Patients Implanted With a Leadless vs Transvenous Single-Chamber Ventricular Pacemaker.

JAMA Cardiol 2021 Jul 28. Epub 2021 Jul 28.

Medtronic, Inc, Minneapolis, Minnesota.

Importance: The safety and efficacy of leadless VVI pacemakers have been demonstrated in multiple clinical trials, but the comparative performance of the device in a large, real-world population has not been examined.

Objective: To compare patient characteristics and complications among patients implanted with leadless VVI and transvenous VVI pacemakers.

Design, Setting, Participants: The Longitudinal Coverage With Evidence Development Study on Micra Leadless Pacemakers (Micra CED) is a continuously enrolling observational cohort study evaluating complications, utilization, and outcomes of leadless VVI pacemakers in the US Medicare fee-for-service population. Read More

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Annual Incidence of Hospitalization for Nonfatal Firearm-Related Injuries in New York From 2005 to 2016.

JAMA Netw Open 2021 Jul 1;4(7):e2115713. Epub 2021 Jul 1.

Division of General Internal Medicine and Mongan Institute, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

Importance: In the US, approximately 40 000 people die due to firearm-related injuries annually. However, nonfatal firearm-related injuries are less precisely tracked.

Objectives: To assess the annual incidence of hospitalization for nonfatal firearm-related injuries in New York and to compare the annual incidence by sex, race/ethnicity, county of residence, and calendar years. Read More

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Echis coloratus envenomation in children: a retrospective case series.

Clin Toxicol (Phila) 2021 Jul 28:1-5. Epub 2021 Jul 28.

Division of Clinical Toxicology, Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.

Background: Antivenom has been used successfully to treat systemic and progressive, local manifestations of envenomations inflicted by , the second most common cause of snake envenomation in Israel. There is a paucity of published data regarding the use of monovalent (equine) immunoglobulin G antivenom in children. This study describes outcomes from the regimen used in two large, tertiary care pediatric centers. Read More

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Remote self-assessment follow-up for medical termination of pregnancy at Geneva University Hospitals: an insight into its acceptability, success rate and costs.

Swiss Med Wkly 2021 Jul 28;151:w20531. Epub 2021 Jul 28.

Service of Gynaecology, Department of Woman, Child and Adolescent, Geneva University Hospitals, Geneva, Switzerland.

Aims Of The Study: Remote follow-up based on self-assessment plus a telephone call with a healthcare provider is a safe and reliable method for assessing the success of medical termination of pregnancy (mTOP) and can lead to an important reduction in costs. The aim of the study was to analyse its efficacy, acceptability and associated costs.

Methods: This was a retrospective comparative study analysing two follow-up protocols for home-based mTOP. Read More

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Impact of COVID-19 Lockdown on Oral Oncology-related Outpatient Volume at Indian Dental Institutions.

J Contemp Dent Pract 2021 May 1;22(5):501-505. Epub 2021 May 1.

Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Saudi Arabia.

Aim And Objective: This study aimed to evaluate the impact of the lockdown on oral oncology-related out-patient volume at Indian dental institutions.

Materials And Methods: The total number of newly diagnosed cases of oral submucous fibrosis, oral leukoplakia, oral lichen planus, and oral cancers, recorded at two dental institutional settings before lockdown (January-March 2020) and after lockdown (June-August 2020), were included retrospectively and compared.

Results: The study included a total of 797 cases at both institutions. Read More

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Dense Polytetrafluoroethylene Membrane versus Titanium Mesh in Vertical Ridge Augmentation: Clinical and Histological Results of a Split-mouth Prospective Study.

J Contemp Dent Pract 2021 May 1;22(5):465-472. Epub 2021 May 1.

Department of Periodontology, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

Aim And Objective: The aim of the present split-mouth prospective study was to evaluate clinically and histologically the bone regeneration obtained following preprosthetic vertical bone augmentation performed with titanium-reinforced dense polytetrafluoroethylene membrane (d-PM) compared to titanium mesh (TM).

Materials And Methods: Healthy adult patients presenting with bilateral partial edentulism in the posterior mandible requiring vertical ridge augmentation for implant placement purposes were consecutively included. One side of the mandible was randomly assigned to the use of d-PM, the other to TM. Read More

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Primary periocular squamous cell carcinoma in central Spain: Factors related to recurrence.

Eur J Ophthalmol 2021 Jul 28:11206721211035629. Epub 2021 Jul 28.

Department of Ophthalmology, Faculdade de Medicina de Botucatu - UNESP, Botucatu, São Paulo, Brazil.

Purpose: To describe the characteristics and recurrence rates of primary periocular squamous cell carcinoma (SCC) in Spain.

Methods: This retrospective study investigates the characteristics of primary periocular SCC at two tertiary centers in Spain from 2000 to 2020. Data were collected on demographics, skin phenotype, location, clinical and histological diagnosis, the commitment of surgical margins, recurrence, and risk factors. Read More

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Intercalation of Thin-Film Gd-Doped Ceria Barrier Layers in Electrolyte-Supported Solid Oxide Cells: Physicochemical Aspects.

ACS Appl Mater Interfaces 2021 Jul 28. Epub 2021 Jul 28.

German Aerospace Centre (DLR), Institute of Engineering Thermodynamics, Pfaffenwaldring 38-40, Stuttgart 70569, Germany.

To minimize alteration of the LaSrCoFeO (LSCF)/GdCeO(CGO20)/YZrO(3YSZ) interface via strontium zirconate formation in solid oxide cells, electron beam physical vapor deposition was employed to manufacture dense, thin gadolinium-doped ceria (CGO) interlayers. CGO layers with thicknesses of 0.15, 0. Read More

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Influence of time to procurement, incubation and release of organ cultured donor corneas on graft failure after Descemet Stripping Automated Endothelial Keratoplasty.

Acta Ophthalmol 2021 Jul 28. Epub 2021 Jul 28.

Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.

Purpose: The aim of the present study was to investigate whether the time from death to procurement, to preservation or the storage time of donor corneas preserved in organ culture influenced the clinical outcome of patients undergoing Descemet stripping automated endothelial keratoplasty (DSAEK) for Fuchs endothelial keratoplasty.

Methods: We conducted a registry-based study on 776 patients undergoing DSAEK. Data on time from donor death to cornea retrieval (DRT), time from death to preservation (DPT), the preservation time and donor cornea characteristics: age, sex and endothelial cell density (ECD) at the time of release for surgery, were extracted from The Danish Cornea Bank Registry. Read More

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Effects of wood kraft pulp feeding on feed digestibility and rumen fermentation of Japanese Black steer in the middle fattening stage.

Anim Sci J 2021 Dec;92(1):e13589

Division of Animal Metabolism and Nutrition, Institute of Livestock and Grassland Science, NARO, Tsukuba, Japan.

We investigated the effects of wood kraft pulp (KP) feeding on feed digestibility and rumen fermentation of Japanese Black (JB) steer in the middle fattening stage. The feeding experiment was carried out a replicated 3 × 3 Latin square design using six JB steers (16.2 ± 0. Read More

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December 2021

Doxycycline pharmacokinetics in geese.

J Vet Pharmacol Ther 2021 Jul 27. Epub 2021 Jul 27.

Department of Veterinary Sciences, University of Pisa, Pisa, Italy.

The study aims to describe the pharmacokinetics of doxycycline after a single intravenous and oral dose (20 mg/kg) in geese. In addition, two multiple-dose simulations have been performed to investigate the predicted plasma concentration after either a 10 or 20 mg/kg daily administration repeated consecutively for 5 days. Ten geese were enrolled in a two-phase cross-over study with a washout period of two weeks. Read More

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Implant-prosthetic rehabilitation of patients with severe horizontal bone deficit on mini-implants with two-piece design-retrospective analysis after a mean follow-up of 5 years.

Int J Implant Dent 2021 Jul 28;7(1):71. Epub 2021 Jul 28.

Clinic for Oral & Maxillofacial Surgery mkg-muc®, Munich, Germany.

Background: As a consequence of tooth loss due to trauma or extraction, a reduced alveolar crest volume limits the deployment of standard implants in certain patient cases. For this reason, minimal-invasive treatment with mini-dental implants (MDI) might be an option to allow implant treatment even in cases with severe horizontal bone loss without augmentation measures. The aim of this retrospective cohort study was to investigate clinical and radiological implant, as well as patient-related parameters after treatment with MDI. Read More

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Adherence to a strict medication protocol can reduce length of stay in hospitalized patients with Parkinson's Disease.

Clin Park Relat Disord 2020 16;3:100076. Epub 2020 Oct 16.

Department of Neurology, Hackensack University Medical Center, Hackensack, NJ, USA.

Background: Patients with Parkinson's Disease (PD) are at higher risk of complications when admitted to the hospital. Delays in PD medications and use of contraindicated medications contribute to the increased risk and prolong their lengths of stay (LOS). Using a hospital-wide PD protocol, we aimed to ensure PD medications were placed with "custom" timing to resemble the home schedules, and also to avoid ordering or administering contraindicated medications. Read More

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October 2020

Hospital-acquired infective endocarditis during Covid-19 pandemic.

2020 Sep 30;2(3):100080. Epub 2020 Jul 30.

Servicio de Medicina Preventiva, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain.

Background: The COVID pandemic has had a major impact on healthcare in hospitals, including the diagnosis and treatment of infections. Hospital-acquired infective endocarditis (HAIE) is a severe complication of medical procedures that has shown a progressive increase in recent years.

Objectives: To determine whether the incidence of HAIE during the first two months of the epidemic (March-April 2020) was higher than previously observed and to describe the clinical characteristics of these cases. Read More

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September 2020