Am J Physiol Renal Physiol 2012 Sep 6;303(5):F605-18. Epub 2012 Jun 6.
School of Computer Science and Software Engineering, The Univ. of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
To understand how geometric factors affect arterial-to-venous (AV) oxygen shunting, a mathematical model of diffusive oxygen transport in the renal cortex was developed. Preglomerular vascular geometry was investigated using light microscopy (providing vein shape, AV separation, and capillary density near arteries) and published micro-computed tomography (CT) data (providing vessel size and AV separation; Nordsletten DA, Blackett S, Bentley MD, Ritman EL, Smith NP. IUPS Physiome Project. Read More