366,256 results match your criteria obesity

Effects of aerobic exercise on obese children with metabolic syndrome: a systematic review and meta-analysis.

J Pediatr Endocrinol Metab 2021 Jul 21. Epub 2021 Jul 21.

Research Center for Physical Fitness and Health Promotion of Adolescent, Guangzhou Sport University, Guangzhou, China.

Objectives: Metabolic syndrome (MetS) is systemic metabolic disease that results from insulin resistance or obesity. Numerous meta-analyses have investigated the effect of exercise on different populations, but none were aimed at the effect of aerobic exercise alone on obese children. This review systematically assessed and performed a meta-analysis on the effect of aerobic exercise on obese children with MetS. Read More

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Metabolic Disorders/Obesity Is a Primary Risk Factor in Hidradenitis Suppurativa: An Immunohistochemical Real-World Approach.

Dermatology 2021 Jul 22:1-9. Epub 2021 Jul 22.

Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.

Background: Hidradenitis suppurativa (HS) is an inflammatory, potentially scarring disease of the hair follicle, affecting the apocrine gland-bearing skin areas. The major comorbid disorders associated with the occurrence or the aggravation of the disease are obesity and smoking. Numerous efforts to dissociate these factors led to controversial results. Read More

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A lacto-ovo-vegetarian dietary pattern is protective against sarcopenic obesity: A cross-sectional study of elderly Chinese people.

Nutrition 2021 Jun 7;91-92:111386. Epub 2021 Jun 7.

Department of Gerontology and Geriatrics, Shengjing Hospital of China Medical University. Electronic address:

Objectives: The purpose of this study was to investigate the correlation between dietary patterns and the risk of sarcopenic obesity (SO) in community-dwelling elderly people.

Methods: SO was defined as the coexistence of sarcopenia and obesity. Participants with low skeletal muscle index, low muscle strength, or low physical performance were diagnosed with sarcopenia, whereas obesity was defined as waist circumference ≥85 cm in men and ≥80 cm in women. Read More

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Resistin: A journey from metabolism to cancer.

Transl Oncol 2021 Jul 20;14(10):101178. Epub 2021 Jul 20.

National Centre for Cell Science, Savitribai Phule Pune University, Ganeshkhind, Pune 411007, India. Electronic address:

Resistin, a small secretory molecule, has been implicated to play an important role in the development of insulin resistance under obese condition. For the past few decades, it has been linked to various cellular and metabolic functions. It has been associated with diseases like metabolic disorders, cardiovascular diseases and cancers. Read More

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Metformin use and risk of asthma exacerbation among asthma patients with glycemic dysfunction.

J Allergy Clin Immunol Pract 2021 Jul 19. Epub 2021 Jul 19.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore Maryland. Electronic address:

Background: Diabetes is associated with worse asthma morbidity. Metformin, which treats diabetes, may have a role among patients with asthma and glycemic dysfunction.

Objective: To determine the association between metformin use and asthma exacerbations among patients with diabetes. Read More

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Does NAFLD Mediate the Relationship Between Obesity and Type 2 Diabetes Risk? Evidence from the Multi-Ethnic Study of Atherosclerosis (MESA).

Ann Epidemiol 2021 Jul 19. Epub 2021 Jul 19.

University of California, Berkeley, School of Public Health, Division of Epidemiology & Biostatistics, Berkeley, CA, USA.

Purpose: To estimate the effect of obesity on type 2 diabetes (T2DM) risk and evaluate to what extent non-alcoholic fatty liver disease (NAFLD) mediates this association.

Methods: Data came from 4,522 adults ages 45-84 participating in the Multi-Ethnic Study of Atherosclerosis cohort. Baseline obesity was defined using established BMI categories. Read More

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Design and evaluation of GLP-1 receptor G-protein biased agonist with prolonged efficacy on diabetes.

Life Sci 2021 Jul 19:119844. Epub 2021 Jul 19.

Peking University Third Hospital, Beijing 100191, PR China. Electronic address:

Aim: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as potent drug development target for treating diabetes and obesity. Here, we designed and evaluated novel long-acting GLP-1R G protein biased agonist with potent clinical application.

Main Methods: GLP-1R G-protein biased sequences were screened via a high-throughput autocrine-based strategy and then fused to Exendin (9-39). Read More

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Rethinking emotional eating: Retrospective and momentary indices of emotional eating represent distinct constructs.

Appetite 2021 Jul 19;167:105604. Epub 2021 Jul 19.

Center for Weight, Eating, and Lifestyle Sciences (WELL Center), Drexel University, Philadelphia, PA, USA. Electronic address:

Emotional eating (EE) has been proposed as a key weight loss barrier. However, most investigations of EE rely on retrospective self-reports, which may have poor construct validity. This study evaluated concordance between a common self-report EE measure and a novel method for assessing momentary EE using ecological momentary assessment (EMA). Read More

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Do perfluoroalkyl substances aggravate the occurrence of obesity-associated glucolipid metabolic disease?

Environ Res 2021 Jul 19;202:111724. Epub 2021 Jul 19.

College of Environmental Science and Engineering, Hunan University, Changsha, 410082, China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, China.

Background: Since 2016, more and more studies have been conducted to explore the combination of obesity and perfluoroalkyl substances (PFASs) exposure, and the results indicate that PFASs may be connected with the occurrence of obesity-associated glucolipid metabolic disease (GLMD).

Objectives: This article summarizes the epidemiological studies on PFASs and obesity-related GLMD, as well as relevant experimental evidence.

Results: (i) Both obesity and PFASs exposure can cause disorder of glucose and lipid metabolism (GLM). Read More

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Exploring the association Between Cardiovascular Health measured with CANHEART model and early cognitive impairment in middle-aged population.

Epidemiol Health 2021 Jul 13:e2021044. Epub 2021 Jul 13.

Yonsei University College of Medicine, Seoul, Korea.

Background: Both cardiovascular health (CVH) and inflammation associated with cognition, and inflammation also associated with cardiovascular health. However, related information in the Korean population is limited. The objective of our study was to confirm the influence of inflammation on the association between CVH and cognition in cross-sectional design. Read More

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Discriminatory capacity of obesity indicators as predictors of high liver fat in US adolescents.

Eur J Clin Invest 2021 Jul 22:e13654. Epub 2021 Jul 22.

Navarrabiomed, Complejo Hospitalario de Navarra (CHN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, Spain.

Background: The aims of this study were to assess the potential of 16 anthropometric, body composition and endocrine indexes as predictors of high liver fat and determine the most appropriate cut-off points in US adolescents.

Methods: A cross-sectional study was conducted on a population of 816 adolescents aged 12-17 years. The FibroScan 502V2 device was used to estimate the controlled attenuation parameter (CAP). Read More

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Oils Rich in α-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity.

J Nutr 2021 Jul 22. Epub 2021 Jul 22.

Department of Food and Human Nutritional Sciences, University of Manitoba, Manitoba, Canada.

Background: Omega-3 fatty acids, including DHA and α-linolenic acid (ALA), are proposed to improve metabolic health by reducing obesity-associated inflammation. Their effects are mediated in part by conversion to oxylipins. ALA is relatively understudied, and direct comparisons to other omega-3 fatty acids are limited. Read More

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Poor adherence to lifestyle recommendations in patients with coronary heart disease: results from the EUROASPIRE surveys.

Eur J Prev Cardiol 2021 Jul 19. Epub 2021 Jul 19.

National Institute for Prevention and Cardiovascular Health, National University of Ireland, Galway, Ireland.

Aims : Despite the high use of cardioprotective medications, the risk factor control in patients with coronary heart disease (CHD) is still inadequate. Guidelines identify healthy lifestyles as equally important in secondary prevention as pharmacotherapy. Here, we describe reasons for poor lifestyle adherence from the patient's perspective. Read More

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Factors associated with mortality in patients hospitalized with COVID-19: A prospective cohort in a Peruvian national referral hospital.

Medwave 2021 Jul 5;21(6):e8231. Epub 2021 Jul 5.

Escuela de Medicina, Universidad Científica del Sur, Lima, Perú. ORCID: 0000-0001-6386-6643.

Objectives: To describe and assess clinical characteristics and factors associated with mortality in adult patients with COVID-19 admitted to a national referral hospital in Peru.

Methods: We conducted a prospective cohort study that included hospitalized patients older than 18 years with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis. Patients with a positive rapid serological test on admission but no respiratory symptoms nor compatible images were excluded. Read More

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Association between the clinical and demographic characteristics of patients undergoing cataract surgery and their prevalence of conjunctival bacteria.

J Cataract Refract Surg 2021 Aug;47(8):1019-1027

From the Ophthalmic Institute Laboratory, Department of Ophthalmology, "Gregorio Marañón" University General Hospital, Madrid, Spain (Fernández-Rubio); Department of Ophthalmology, "Gregorio Marañón" University General Hospital, Madrid, Spain (Urcelay-Segura, Cuesta-Rodríguez); "Gregorio Marañón" Health Research Institute, "Gregorio Marañón" University General Hospital, Madrid, Spain (Bellón-Cano).

Purpose: To identify characteristics of patients undergoing cataract surgery associated with pathogenic and antibiotic-resistant conjunctival bacteria.

Setting: Spanish tertiary hospital.

Design: Retrospective cross-sectional study. Read More

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Agomelatine prevents angiotensin II-induced endothelial and mononuclear cell adhesion.

Aging (Albany NY) 2021 Jul 22;13(undefined). Epub 2021 Jul 22.

Department of Stomatology, Tibet Corps Hospital, Chinese People's Armed Police Forces, Lhasa 850000, Tibet Autonomous Region, China.

Agomelatine is a non-selective melatonin receptor agonist and an atypical antidepressant with anti-inflammatory, neuroprotective, and cardioprotective effects. The renin-angiotensin system modulates blood pressure and vascular homeostasis. Angiotensin II (Ang II) and its receptor Ang II type I receptor (ATR) are recognized as contributors to the pathogenesis of cardiovascular and cardiometabolic diseases, including diabetes, obesity, and atherosclerosis. Read More

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Use of 3D Navigation Versus Traditional Fluoroscopy for Posterior Pelvic Ring Fixation.

Orthopedics 2021 Jul-Aug;44(4):229-234. Epub 2021 Jul 1.

Unstable pelvic ring disruption is most commonly treated with closed reduction and percutaneous screw fixation. Traditional methods involve screw placement under fluoroscopic imaging, but with recent technologic advances, intraoperative 3D navigation can now be used to help with the insertion of sacroiliac screws. Various cadaver studies have shown that placement of sacroiliac screws under 3D navigation is more accurate than placement under traditional fluoroscopic guidance. Read More

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Fertility-sparing approach for endometrial cancer: the role of office hysteroscopy.

Minim Invasive Ther Allied Technol 2021 Jul 22:1-8. Epub 2021 Jul 22.

Department of Obstetrics and Gynecology, University of California Davis Medical Center, Sacramento, CA, USA.

Endometrial cancer is the most common gynecologic malignancy in developed countries, with increasing incidence among younger, nulliparous patients. These epidemiological shifts are attributed to increasing rates of obesity, in combination with delayed childbearing. This highlights a need for fertility-sparing options for individuals who wish to delay standard surgical management with hysterectomy, bilateral salpingoophorectomy, and assessment of pelvic/para-aortic lymph nodes. Read More

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Remote Patient Monitoring Identifies the Need for Triage in Patients with Acute COVID-19 Infection.

Telemed J E Health 2021 Jul 22. Epub 2021 Jul 22.

Department of Rehabilitation and Human Performance and Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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Noninvasive ventilation vs. high-flow nasal cannula oxygen for preoxygenation before intubation in patients with obesity: a post hoc analysis of a randomized controlled trial.

Ann Intensive Care 2021 Jul 22;11(1):114. Epub 2021 Jul 22.

Médecine Intensive Réanimation, CHU de Poitiers, Poitiers, France.

Background: Critically ill patients with obesity may have an increased risk of difficult intubation and subsequent severe hypoxemia. We hypothesized that pre-oxygenation with noninvasive ventilation before intubation as compared with high-flow nasal cannula oxygen may decrease the risk of severe hypoxemia in patients with obesity.

Methods: Post hoc subgroup analysis of critically ill patients with obesity (body mass index ≥ 30 kg·m) from a multicenter randomized controlled trial comparing preoxygenation with noninvasive ventilation and high-flow nasal oxygen before intubation of patients with acute hypoxemic respiratory failure (PaO/FiO < 300 mm Hg). Read More

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Disparities in Elevated Body Mass Index in Youth Receiving Care at Community Health Centers.

Fam Community Health 2021 Jul 20. Epub 2021 Jul 20.

AllianceChicago, Chicago, Illinois (Dr Mohanty and Ms Padilla); SASU Project Management (Ms Rittner) and General Internal Medicine and Geriatrics, Department of Medicine (Dr Persell), Northwestern University Feinberg School of Medicine (Dr Mohanty), Chicago, Illinois; Center for Health Research, Kaiser Permanente Northwest, Portland, Oregon (Dr Leo and Mr Crawford); University of Chicago, Chicago, Illinois (Ms Tilmon); Division of Cardiology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey (Dr Akhabue); and University of Hawaii at Manoa, Honolulu (Dr Okihiro).

Childhood obesity has increased significantly in the United States. Racial subgroups are often grouped into categories in research, limiting our understanding of disparities. This study describes the prevalence of obesity among youth of diverse racial and ethnic backgrounds receiving care at community health centers (CHCs). Read More

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Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women: Protocol for a Pilot Study.

JMIR Res Protoc 2021 Jul 22;10(7):e29191. Epub 2021 Jul 22.

Social Determinants of Obesity and Cardiovascular Risk Laboratory, Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States.

Background: Innovative analyses of cardiovascular (CV) risk markers and health behaviors linked to neighborhood stressors are essential to further elucidate the mechanisms by which adverse neighborhood social conditions lead to poor CV outcomes. We propose to objectively measure physical activity (PA), sedentary behavior, and neighborhood stress using accelerometers, GPS, and real-time perceived ecological momentary assessment via smartphone apps and to link these to biological measures in a sample of White and African American women in Washington, DC, neighborhoods.

Objective: The primary aim of this study is to test the hypothesis that living in adverse neighborhood social conditions is associated with higher stress-related neural activity among 60 healthy women living in high or low socioeconomic status neighborhoods in Washington, DC. Read More

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Measuring the Healthiness of Ready-to-Eat Child-Targeted Cereals: Evaluation of the FoodSwitch Platform in Sweden.

JMIR Mhealth Uhealth 2021 Jul 22;9(7):e17780. Epub 2021 Jul 22.

The George Institute for Global Health, University of New South Wales, Sydney, Australia.

Background: Childhood obesity is a major public health issue. The increase in the consumption of foods with poor nutritional value, such as processed foods, contributes to this. Breakfast cereals are often advertised as a healthy way to start the day, but the healthiness of these products varies greatly. Read More

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Prebiotic inulin as a treatment of obesity related nonalcoholic fatty liver disease through gut microbiota: a critical review.

Crit Rev Food Sci Nutr 2021 Jul 22:1-11. Epub 2021 Jul 22.

Key laboratory of Animal Disease-resistant Nutrition, Ministry of Education, Animal Nutrition Institute, Sichuan Agricultural University, Yaan, People's Republic of China.

The microbial-derived products, including short chain fatty acids, lipopolysaccharide and secondary bile acids, have been shown to participate in the regulation of hepatic lipid metabolism. Previous studies have demonstrated that prebiotics, such as oligosaccharide and inulin, have abilities to change the concentration of microbial-derived products through modulating the microbial community structure, thus controlling body weight and alleviating hepatic fat accumulation. However, recent evidence indicates that there are individual differences in host response upon inulin treatment due to the differences in host microbial composition before dietary intervention. Read More

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Adolescent academic worries amid COVID-19 and perspectives on pandemic-related changes in teacher and peer relations.

Sch Psychol 2021 Jul 22. Epub 2021 Jul 22.

Rudd Center for Food Policy and Obesity, University of Connecticut.

Despite recognition of the potential impact of the COVID-19 pandemic on secondary schooling experiences, little empirical evidence has captured adolescents' perspectives on the extent of academic and social disruption resulting from the pandemic. The present study examined adolescents' academic worries amid the COVID-19 pandemic and their perspectives on pandemic-related changes in teacher and peer relations. Participants were 452 adolescents (55% female) between the ages of 11 and 17, who completed online surveys asking them about their worries about their schoolwork and educational futures, perceived support from teachers, and perceptions of electronic (cyber) bullying during the pandemic. Read More

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Eating disorder measures in a sample of military veterans: A focus on gender, age, and race/ethnicity.

Psychol Assess 2021 Jul 22. Epub 2021 Jul 22.

National Center for PTSD.

Early detection of eating disorders (EDs) is crucial for both prevention and treatment; however, few ED measures have been validated among older adults, men, and racially/ethnically diverse individuals, who may have varying symptom presentations. We examined the psychometric quality of three self-report ED measures within a diverse sample of U.S. Read More

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Independent associations of sleep timing, duration and quality with adiposity and weight status in a national sample of adolescents: The UK Millennium Cohort Study.

Paul J Collings

J Sleep Res 2021 Jul 22:e13436. Epub 2021 Jul 22.

Department of Health Sciences, University of York, York, UK.

Short sleep appears to elevate obesity risk in youth; however, sleep is a multidimensional construct, and few studies have investigated parameters beyond duration. The objective of this study was to investigate if sleep onset time, duration, latency and night waking frequency are independently associated with adiposity and weight status in UK adolescents. This was a cross-sectional observational study of 10,619, 13-15 years olds. Read More

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Asthma in Youth and Early-Onset Type 2 Diabetes: A Nationwide Study of 1.72 Million Israeli Adolescents.

J Clin Endocrinol Metab 2021 Jul 22. Epub 2021 Jul 22.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: The prevalence of both asthma and early onset diabetes is on the rise, however the association between them remains unclear. We examined a possible association of asthma at adolescence with type 2 diabetes in young adulthood.

Methods: This is a nationwide, population-based study of 1,718,541 Israeli adolescents (59% males; mean age 17. Read More

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Visceral Adipose Tissue Volumetrics Inform Odds of Treatment Response and Risk of Subsequent Surgery in IBD Patients Starting Antitumor Necrosis Factor Therapy.

Inflamm Bowel Dis 2021 Jul 22. Epub 2021 Jul 22.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Texas at Austin Dell Medical School, Austin,  TX, USA.

Background: Data describing the effect of obesity on antitumor necrosis factor (anti-TNF) treatment response are inconsistent. Visceral adipose tissue (VAT) is a superior marker of adiposity to body mass index. However, its effect on treatment response is unclear. Read More

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Anthropometric measures and blood pressure of Greenlandic preschool children.

Int J Circumpolar Health 2021 Dec;80(1):1954382

Center for Arctic Health and Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.

The study aims to describe anthropometric data of Greenlandic preschool children, blood pressure (BP) measures and effects of maternal smoking during pregnancy in a follow-up of the ACCEPT birth cohort. The study included 102 children (55 boys and 47 girls) aged 3.5-5. Read More

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December 2021