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Pain and numbness one month after carpal tunnel release predict patient-reported outcome measures at sixth months.

J Plast Surg Hand Surg 2021 Jul 29:1-5. Epub 2021 Jul 29.

Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.

A number of outcome predictors for carpal tunnel release (CTR) for carpal tunnel syndrome (CTS) have been reported. However, some predictors are controversial, and few studies have referred to the early postoperative outcome prognostic factors after CTR. The aim of this study was to investigate whether pain and numbness at 1 month post-CTR were early postoperative predictors of clinical outcomes 6 months after surgery. Read More

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Effect of Endoscopic Appendix Intubation and Irrigation on Acute Uncomplicated Appendicitis.

World J Surg 2021 Jul 29. Epub 2021 Jul 29.

The Endoscope Center, The First Afilliated Hospital of Fujian Medical University, No.20, Chazhong road, Taijiang District, Fuzhou, 350005, China.

Objective: To investigate the efficacy and safety of endoscopic appendix intubation and irrigation (EAI) on acute uncomplicated appendicitis.

Methods: This prospective non-randomized study examined 169 patients with suspected acute uncomplicated appendicitis at The First Affiliated Hospital of Fujian Medical University from October 2015 to 2017. Patients were divided into three groups: endoscopic appendix intubation and irrigation (EAI, n = 18), laparoscopic appendectomy (LA, n = 87), and antibiotic alone (A, n = 64). Read More

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Role of anaesthesia in endoscopic and external dacryocystorhinostomy: A meta-analysis of 3282 cases.

Eur J Ophthalmol 2021 Jul 28:11206721211035616. Epub 2021 Jul 28.

Division of Head and Neck Department, Otorhinolaryngology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Distal acquired lacrimal obstruction is a common adulthood pathology whose primary treatment is represented by EXT-DCR and END-DCR. When considering their influencing factors, the role of the type of anaesthesia applied during these surgeries has a major role. The aim of this study is to systematically analyse the influence of general and local/regional anaesthesia on the final success rates of EXT-DCR and END-DCR. Read More

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Development of a narrow-band imaging classification to reduce the need for routine biopsies of gastric polyps.

Gastroenterol Rep (Oxf) 2021 Jun 27;9(3):219-225. Epub 2020 Dec 27.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

Background: Most incidental gastric polyps identified during upper endoscopy are considered low-risk. However, current guidelines recommend sampling all gastric polyps for histopathologic analysis. We aimed to devise a simple narrow-band imaging (NBI) classification to reduce the need for routine biopsies of low-risk gastric polyps. Read More

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Thulium laser vapo-enucleation treatment for prostates >100 cc following urinary retention.

Urologia 2021 Jul 27:3915603211016325. Epub 2021 Jul 27.

University Hospitals of Leicester NHS Trust, Leicester, UK.

Introduction: Practical advantages of Thulium in the endoscopic treatment of BPH include its technical versatility, precision and safety, offering reduced need for haemostasis and risk of injury. Evidence has shown Holmium laser to be effective in the treatment of chronic retention, however no studies address the use of Thulium laser for larger prostates after urinary retention.

Objectives: We have selected this group in our retrospective analysis on the efficacy of Thulium laser vapo-enucleation for men with both urinary retention and large prostate volumes greater than 100 cc. Read More

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Normative Ambulatory Reflux Monitoring Metrics for Laryngopharyngeal Reflux: A Systematic Review of 720 Healthy Individuals.

Otolaryngol Head Neck Surg 2021 Jul 27:1945998211029831. Epub 2021 Jul 27.

Department of Otorhinolaryngology-Head & Neck Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

Objectives: To review the normative data for acid, weakly acid, and nonacid proximal esophageal (PRE) and hypopharyngeal reflux (HRE) events in diagnosing laryngopharyngeal reflux (LPR) using ambulatory reflux monitoring.

Data Sources: PubMed, Cochrane Library, and Scopus.

Review Methods: A literature search was conducted about the normative data for PRE and HRE on multichannel intraluminal impedance-pH monitoring (MII-pH), hypopharyngeal-esophageal MII-pH (HEMII-pH), or oropharyngeal pH monitoring using PICOTS (population, intervention, comparison, outcome, timing, and setting) and PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statements. Read More

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Endotype-related recurrence pattern of chronic rhinosinusitis in revision functional endoscopic sinus surgery.

Auris Nasus Larynx 2021 Jul 23. Epub 2021 Jul 23.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Boramae Medical Center, Seoul, South Korea. Electronic address:

Objective: The recurrence of chronic rhinosinusitis (CRS) after functional endoscopic sinus surgery (FESS) is influenced by various factors, potentially including the endotype based on the molecular pathophysiology of CRS. This study investigated differences in the recurrence pattern of CRS by endotype after primary FESS.

Methods: This retrospective study enrolled patients who had undergone revision FESS for recurrent CRS. Read More

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COVID-19 in the Clinic: Human Testing of an Aerosol Containment Mask for Endoscopic Clinic Procedures.

Otolaryngol Head Neck Surg 2021 Jul 27:1945998211029184. Epub 2021 Jul 27.

Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.

Objective: To create an aerosol containment mask (ACM) for common otolaryngologic endoscopic procedures that also provides nanoparticle-level protection to patients.

Study Design: Prospective feasibility study .

Setting: In-person testing with a novel ACM. Read More

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Nursing Difficulties and Issues in Endoscopic Sedation: Qualitative Research in Japan.

Gastroenterol Nurs 2021 Jul 20. Epub 2021 Jul 20.

Miki Matsubayashi, MSN, is Clinical Nurse, Social Medical Corporation Sousei Hospital, Kadoma City, Osaka, Japan. Keiko Nakamura, DNP, is Specially Appointed Professor, Acute Illness, Adult Nursing, Graduate School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan. Miki Sugawara, DNP, is Associate Professor, Acute Illness, Adult Nursing, Graduate School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan. Shigeko Kamishima, DNP, is Associate Professor, Acute Illness, Adult Nursing, Graduate School of Nursing, Sapporo City University, Sapporo, Hokkaido, Japan.

Gastrointestinal endoscopic treatments have increased in Japan. Respiratory depression is as an unexpected development during sedation. This study aimed to clarify the sedation-related difficulties encountered by nurses involved in endoscopic treatment. Read More

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Cost-effectiveness analysis comparing dupilumab and aspirin desensitization therapy for chronic rhinosinusitis with nasal polyposis in aspirin-exacerbated respiratory disease.

Int Forum Allergy Rhinol 2021 Jul 26. Epub 2021 Jul 26.

Faculty of Medicine, Division of Otolaryngology-Head and Neck Surgery, University of British Columbia, Vancouver, BC, Canada.

Background: Chronic rhinosinusitis with nasal polyposis (CRSwNP) in the setting of aspirin-exacerbated respiratory disease (AERD) is a disease that is difficult to treat and prone to recurrence. Dupilumab is a promising treatment for these patients, but its cost-effectiveness has not yet been compared with aspirin (acetylsalicyclic acid, or ASA) desensitization, a known and effective treatment. We aimed to compare the cost-effectiveness of ASA desensitization with dupilumab therapy for the treatment of CRSwNP in AERD. Read More

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Contemporary management of benign uretero-enteric strictures after cystectomy: a systematic review.

Minerva Urol Nephrol 2021 Jul 26. Epub 2021 Jul 26.

Urology Department, Sant'Andrea Hospital, Università degli Studi di Roma La Sapienza, Rome, Italy.

Introduction: Uretero-enteric stricture (UES) is a common post-operative complication after radical cystectomy with urinary diversion. The aim of this systematic review is to discuss the contemporary management of benign UES after cystectomy and to compare the different surgical approaches.

Evidence Acquisition: A systematic review was performed from January 2000 through January 2021. Read More

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Benefit of Endoscopic Surgery in the Management of Acute Invasive Skull Base Fungal Rhinosinusitis.

J Neurol Surg B Skull Base 2021 Jul 11;82(Suppl 3):e330-e334. Epub 2020 Feb 11.

Department of Neurosurgery, Mount Sinai Medical Center, One Gustave L. Levy Place, New York, United States.

 This article aims to characterize 14 patients who underwent purely endoscopic surgical debridement of acute invasive skull base fungal rhinosinusitis, and to evaluate postoperative outcomes and risk for recurrence.  Retrospective cohort study.  Tertiary single-institution neurosurgery department. Read More

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Clinical observation of octreotide combined with diclofenac sodium in preventing ERCP-related pancreatitis.

Am J Transl Res 2021 15;13(6):7179-7185. Epub 2021 Jun 15.

Department of Gastrointestinal Surgery, Nanhua Hospital, Nanhua University Hengyang, Hunan Province, China.

Objective: To elucidate the efficacy of octreotide in combination with diclofenac sodium in the prevention of ERCP-related pancreatitis, and investigate its impact on patients' serum amylase, white blood cell (WBC) count, adverse effects, hyperamylasemia and hemorheology.

Methods: The prospective study was conducted, in which 124 patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) in our hospital were evenly divided into 2 groups, the observation group (n=62) and the control group (n=62), via a random number table method. The control group was administered diclofenac sodium lidocaine hydrochloride via injection after ERCP, while the observation group was given octreotide acetate on the basis of the control group. Read More

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Multiclassification of Endoscopic Colonoscopy Images Based on Deep Transfer Learning.

Comput Math Methods Med 2021 3;2021:2485934. Epub 2021 Jul 3.

College of Information Science and Engineering, Hunan Normal University, Changsha 410081, China.

With the continuous improvement of human living standards, dietary habits are constantly changing, which brings various bowel problems. Among them, the morbidity and mortality rates of colorectal cancer have maintained a significant upward trend. In recent years, the application of deep learning in the medical field has become increasingly spread aboard and deep. Read More

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Mimicking conditions of intestinal Crohn's disease: magnetic resonance enterography findings.

Jpn J Radiol 2021 Jul 25. Epub 2021 Jul 25.

Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Policlinico "G. Martino", Via Consolare Valeria 1, 98100, Messina, Italy.

Crohn's disease is a chronic inflammatory condition characterized by a transmural involvement of intestinal walls. Its diagnosis comes from a combination of clinical data, imaging findings and, above all, endoscopy with biopsy results, which are mandatory for achieving a definitive diagnosis. Even so, endoscopy information may be unavailable, for instance due to technical impairments or patient intolerance. Read More

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Multicenter prospective in vivo study of an endocytoscope system (ECS) for superficial esophageal cancer.

J Gastroenterol 2021 Jul 25. Epub 2021 Jul 25.

Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

Background: Endocytoscope systems (ECS) can visualize cellular nuclei of the mucosa of the gastrointestinal tract and are predicted to provide real-time microscopic diagnosis. However, their practical diagnostic performance remains unclear. Therefore, we conducted a multicenter prospective study to evaluate the visualization of superficial esophageal neoplasm in vivo using an ECS, and its diagnostic capability. Read More

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Heyde syndrome: prevalence and outcomes in patients undergoing transcatheter aortic valve implantation.

Clin Res Cardiol 2021 Jul 23. Epub 2021 Jul 23.

Department of Cardiology, University Heart and Vascular Center Hamburg, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.

Background: Heyde syndrome (HS) is known as the association of severe aortic stenosis (AS) and recurrent gastrointestinal bleeding (GIB) from angiodysplasia. Data on the prevalence of HS and results after TAVI remain scarce.

Methods: 2548 consecutive patients who underwent TAVI for the treatment of AS from 2008 to 2017 were evaluated for a history of GIB and the presence of HS. Read More

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New Trends and Advances in Non-Variceal Gastrointestinal Bleeding-Series II.

J Clin Med 2021 Jul 8;10(14). Epub 2021 Jul 8.

IIS Aragón, CIBERehd, 50009 Zaragoza, Spain.

The gastrointestinal tract is a long tubular structure wherein any point in the mucosa along its entire length could be the source of a hemorrhage. Upper (esophagel and gastroduodenal) and lower (jejunum, ileum, and colon) gastrointestinal bleeding are common. Gastroduodenal and colonic bleeding are more frequent than bleeding from the small bowel, but nowadays the entire gastrointestinal tract can be explored endoscopically and bleeding lesions can be locally treated successfully to stop or prevent further bleeding. Read More

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Commonly available but highly effective protection against SARS-CoV-2 during gastrointestinal endoscopies.

PLoS One 2021 23;16(7):e0254979. Epub 2021 Jul 23.

Department of Internal Medicine, 2nd Faculty of Medicine Charles University in Prague and Motol University Hospital, Prague, Czech Republic.

Background And Aims: SARS-CoV-2 is a worldwide serious health problem. The aim of this study was to demonstrate the number of potentially infectious particles present during endoscopic procedures and find effective tools to eliminate the risks of SARS-CoV-2 infection while performing them.

Methods: An experimental model which focused on aerosol problematics was made in a specialized laboratory. Read More

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Gas Leak and Mucosal Injury During Endoscopic Esophageal Myotomy After Previous Myotomy: A Single-Center Experience.

Clin Exp Gastroenterol 2021 20;14:173-179. Epub 2021 May 20.

Division of Digestive Diseases-Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

Purpose: Peroral endoscopic myotomy (POEM) after prior myotomy (PM-POEM) can be technically challenging with possible increased adverse events. We aimed to assess gas leak and mucosal injury incidence during PM-POEM, compared to an index POEM (iPOEM), and post-procedure extubation time.

Patients And Methods: A retrospective study comparing PM-POEM to iPOEM from March 2016 to August 2018. Read More

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The Effect of Preoperative Anxiety and Pain Sensitivity on Preoperative Hemodynamics, Propofol Consumption, and Postoperative Recovery and Pain in Endoscopic Ultrasonography.

Pain Ther 2021 Jul 22. Epub 2021 Jul 22.

Department of Anaesthesiology and Reanimation, Faculty of Medicine, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi, Dr. Erkin Cad., Kadikoy, 34722, Istanbul, Turkey.

Introduction: The present study investigates how preoperative anxiety and pain sensitivity affect the consumption of anesthetics, time elapsed until the desired sedation level is achieved, preoperative hemodynamics, postoperative recovery time, and postoperative pain.

Methods: The present study includes 80 ASA 1-2 patients aged between 20 and 65 who were scheduled for endoscopic ultrasonography (EUS) under sedation. Patients were instructed to fill out the Spielberger State-Trait Anxiety Inventory (STAI) and Pain Sensitivity Questionnaire (PSQ) before the procedure. Read More

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Human Growth and Growth Hormone: From Antiquity to the Recominant Age to the Future.

Front Endocrinol (Lausanne) 2021 5;12:709936. Epub 2021 Jul 5.

Pediatrics/Endocrinology, University of Virginia, Charlottesville, VA, United States.

Since antiquity Man has been fascinated by the variations in human (and animal) growth. Stories and art abound about giants and little people. Modern genetics have solved some of etiologies at both extremes of growth. Read More

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EUS-guided biopsy confocal laser endomicroscopy in patients with pancreatic cystic lesions: A systematic review and meta-analysis.

Endosc Ultrasound 2021 Jul 19. Epub 2021 Jul 19.

Gastro Unit, Pancreatitis Centre East, Hvidovre Hospital, Hvidovre; Department of Clinical Medicine, University of Copenhagen, København, Denmark.

Background And Objectives: Pancreatic cystic lesions (PCLs) are frequent incidental findings on cross-sectional imaging and represent a diagnostic challenge as different kinds of PCLs harbor a dissimilar risk of malignancy. Two diagnostic tools have recently been developed and introduced: through-the-needle biopsy (TTNB) and needle-based confocal laser endomicroscopy (nCLE). The aim of this meta-analysis was to compare the diagnostic yield and performance, as well as the safety profile of the two methods. Read More

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Epidemiology, risk factors, and prediction score of carbapenem resistance among inpatients colonized or infected with 3rd generation cephalosporin resistant Enterobacterales.

Sci Rep 2021 Jul 20;11(1):14757. Epub 2021 Jul 20.

Department of Laboratory Medicine, Makassed General Hospital, Beirut, Lebanon.

In this study, we determined the incidence and risk factors of Carbapenem-resistant Enterobacterales (CRE) acquisition in inpatients with 3rd generation cephalosporin-resistant (3GCR) Enterobacterales at a tertiary-care hospital in Lebanon, and suggested a risk prediction score for it. This is a retrospective matched case-control study of inpatients with 3GCR Enterobacterales that are carbapenem resistant (cases) versus those with carbapenem-sensitive isolates (controls). Data analysis was performed on IBM SPSS program, version 23. Read More

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Comparison of the transoral endoscopic thyroidectomy vestibular approach and open thyroidectomy: A propensity score-matched analysis of surgical outcomes and safety in the treatment of papillary thyroid carcinoma.

Surgery 2021 Jul 17. Epub 2021 Jul 17.

Department of Thyroid Surgery, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang, China.

Background: The transoral endoscopic thyroidectomy vestibular approach has been demonstrated to have similar surgical outcomes as open thyroidectomy for selected papillary thyroid carcinomas. This study aimed to evaluate and compare the surgical outcomes and safety of the transoral endoscopic thyroidectomy vestibular approach with those of open thyroidectomy in the treatment of papillary thyroid carcinoma with a diameter between >1 cm and ≤3.5cm. Read More

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[Position paper on endoscopic reporting in IBD].

Z Gastroenterol 2021 Jul 20. Epub 2021 Jul 20.

Medizinische Klinik 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

The complete and reliable documentation of endoscopic findings make up the crucial foundation for the treatment of patients with inflammatory bowel diseases such as Crohn´s disease and ulcerative colitis. These findings are, on the one hand, a prerequisite for therapeutic decisions and, on the other hand, important as a tool for assessing the response to ongoing treatments. Endoscopic reports should, therefore, be recorded according to standardized criteria to ensure that the findings of different endoscopists can be adequately compared and that changes in the course of the disease can be traced back. Read More

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Occupational exposure influences control of disease in patients with chronic rhinosinusitis.

Rhinology 2021 Jul 20. Epub 2021 Jul 20.

Department of Otorhinolaryngology, Amsterdam University Medical Centres, location AMC, Amsterdam, The Netherlands.

Background: Chronic rhinosinusitis (CRS) is a frequent condition that is treated by endoscopic sinus surgery (ESS) when medical treatment fails. Irritating or sensitizing airborne agents can contribute to uncontrolled CRS. A prior study showed a linear correlation between occupational exposure and the number of ESS. Read More

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Effectiveness of Laparoscopic Combined Retroperitoneal and Transperitoneal Approach in Para-aortic Lymphadenectomy for Endometrial Cancer.

Anticancer Res 2021 Aug;41(8):4151-4155

Department of Obstetrics and Gynecology, Mie University School of Medicine, Mie, Japan.

Background/aim: This study aimed to compare laparoscopy with laparotomy and evaluate the effectiveness of a laparoscopic combined retroperitoneal and transperitoneal approach for para-aortic lymphadenectomy in patients with endometrial cancer.

Patients And Methods: In this single-center retrospective study, patients with endometrial cancer who underwent para-aortic lymphadenectomy between December 2016 and November 2019 were analyzed. The patient's clinical and pathologic data were procured from medical records. Read More

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Patient-centered approaches to targeting incomplete bowel preparations for inpatient colonoscopies.

Ann Gastroenterol 2021 Jul-Aug;34(4):547-551. Epub 2021 Apr 2.

Department of Medicine, University of Alberta, Edmonton AB (Lindsey Russell, Pamela Mathura, Amanda Lee, Raveena Dhaliwal, Narmin Kassam, Ali Kohansal).

Background: A high-quality colonoscopy bowel prep is vital to completing the procedure. Adequate inpatient bowel preparation has been consistently difficult to achieve because of multiple factors. Incomplete bowel prep can lead to repeated colonoscopies, poor patient experience, increased costs, and prolonged hospitalization. Read More

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