7,480 results match your criteria nulliparous women

Prior Term Birth Decreases the Risk of Preterm Birth in a Subsequent Twin Gestation.

Am J Perinatol 2021 May 4. Epub 2021 May 4.

Department of Obstetrics, Gynecology, and Reproductive Sciences, California Pacific Medical Center, San Francisco, California.

Objective:  The aim of the study is to examine the association between the risk of preterm delivery among women with twin pregnancies and their obstetric history.

Study Design:  We designed a retrospective cohort study of live twin births in 2008 in the United States that delivered after 24 weeks. Women were categorized into nulliparas, multiparas with prior term delivery, and multiparas with prior preterm delivery. Read More

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The effect of yoga on the delivery and neonatal outcomes in nulliparous pregnant women in Iran: a clinical trial study.

BMC Pregnancy Childbirth 2021 May 3;21(1):351. Epub 2021 May 3.

Clinical Research Development Unit, Kowsar Hospital, Qazvin University of Medical Science, Qazvin, Iran.

Background: Yoga can reduce the risk of preterm delivery, cesarean section (CS), and fetal death. The aim of the present study was to investigate the effects of Yoga on pregnancy, delivery, and neonatal outcomes.

Methods: This was a clinical trial study and using the random sampling without replacement 70 pregnant women entered Hatha Yoga and control groups according to the color of the ball they took from a bag containing two balls (blue or red). Read More

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Considering Criteria for Active Phase Labor Management of Nulliparous Women: A Cost-Effectiveness Analysis.

Am J Perinatol 2021 May 3. Epub 2021 May 3.

Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon.

Objective:  The aim of the study is to evaluate differences in maternal and neonatal outcomes based on updated criteria for defining active labor at 6 cm of cervical dilation and to determine if these recommendations are cost-effective.

Study Design:  A decision-analytic model was built using TreeAge Pro 2020 software. We included maternal outcomes of mode of delivery, endometritis, postpartum hemorrhage requiring transfusion, and death. Read More

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Midtrimester Cervical Length in Low-Risk Nulliparous Women for the Prediction of Spontaneous Preterm Birth: Should We Consider a New Definition of Short Cervix?

Am J Perinatol 2021 May 3. Epub 2021 May 3.

Research Center, CHU de Québec-Université Laval, Québec, Canada.

Objective:  The study aimed to estimate the predictive value of midtrimester cervical length (CL) and the optimal cut-off of CL that should be applied with asymptomatic nulliparous women for the prediction of spontaneous preterm birth (sPTB).

Study Design:  This is a prospective cohort study of asymptomatic nulliparous women with a singleton gestation. Participants underwent CL measurement by transvaginal ultrasound between 20 and 24 weeks of gestation. Read More

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3D high frequency endovaginal ultrasound evaluation of urethral and pelvic morphology in stress urinary incontinence in first pregnancy.

Eur J Obstet Gynecol Reprod Biol 2021 Apr 27;261:148-153. Epub 2021 Apr 27.

Department of Obstetrics&Gynecology, Maltepe University Faculty of Medicine, Ataturk Caddesi, Cam Sokak. No:3/A 34843 Maltepe, Istanbul, Turkey. Electronic address:

Objective: We aimed to compare the morphological characteristics of pelvis and urethra in nulliparous pregnant women with and without stress urinary incontinence (SUI) by 3D high-frequency endovaginal ultrasound (3D-EVUS).

Study Design: At 36-38 weeks of gestation, 40 nulliparous pregnant women with and without SUI underwent 3D-EVUS assessment. The anteroposterior and transverse diameters of levator hiatus (LH), pubovisceral muscle thicknesses at 3,9 and 12 o'clock, right and left paravaginal areas, symphysis angle, bladder-symphysis distance (BSD), uretral complex thickness (Ut), urethral complex width (Uw), urethral complex volume (UV), urethral length (UL), intramural urethra, rhabdosphincter thickness (Rt), rhabdosphincter width (Rw), rhabdosphincter length (RL), and rhabdosphincter volume (RV) were measured by 3D-EVUS. Read More

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Caesarean section rates: applying the modified ten-group Robson classification in an Australian tertiary hospital.

J Obstet Gynaecol 2021 May 2:1-6. Epub 2021 May 2.

Department of Obstetrics and Gynaecology, The Royal Brisbane and Women's Hospital, Brisbane, Australia.

The aim of this study was to determine the main contributors to caesarean section (CS) rates at an Australian tertiary hospital. We conducted a retrospective review of women who delivered in an Australian tertiary hospital between 2014 and 2017. Women were allocated according to a modified Robson Ten-Group Classification System and CS indications were collected in nulliparous women and women with previous CS. Read More

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Progression of the first stage of labour, in low risk nulliparas in a South Asian population: a prospective observational study.

J Obstet Gynaecol 2021 May 2:1-5. Epub 2021 May 2.

Department of Obstetrics and Gynaecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

We compared the labour pattern in the active phase of labour, defined at 4 cm versus 6 cm cervical dilatation, in a South Asian population. This was a prospective observational study where 500 low risk nulliparous women were recruited. Our aim was to study, the average labour pattern curve of all parturients. Read More

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Evaluation of trunk muscle activities in response to three breastfeeding positions utilised by women.

J Back Musculoskelet Rehabil 2021 Apr 26. Epub 2021 Apr 26.

School of Health Technology, Oji-River, Enugu State, Nigeria.

Background: High prevalence of breastfeeding (BF)-related musculoskeletal disorders (MSDs) in nursing mothers have been reported in previous studies. Studies are scarce on the biomechanical effects of the commonly utilized BF positions.

Objective: This study evaluated the electromyographic (EMG) activities of the trunk muscles in response to three BF positions commonly utilized by mothers globally. Read More

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Is Exposure to Intrapartum Prostaglandins for Labor Induction Associated with a Lower Incidence of Neonatal Respiratory Distress Syndrome?

Am J Perinatol 2021 May 2. Epub 2021 May 2.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah.

Objective:  Respiratory distress syndrome (RDS) is implicated in 30% of neonatal deaths. Since prostaglandins promote surfactant secretion and labor is associated with a lower risk of RDS in term neonates, it is plausible that synthetic prostaglandin (sPG) exposure is associated with a lower risk of RDS. Thus, we evaluated the association between sPG exposure and RDS in neonates born after the induction of labor (IOL). Read More

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Literature Review of the Association Between Prenatal Education and Rates of Cesarean Birth Among Women at Low Risk.

Sabrina Ronco

Nurs Womens Health 2021 Apr 29. Epub 2021 Apr 29.

A review of the literature was performed to explore the association between prenatal education and rates of primary cesarean birth for women at low risk for cesarean birth. Most women who are nulliparous with a singleton fetus of term gestational age and in the vertex position are considered to be at low risk and favorable for a vaginal birth, yet the cesarean birth rate for women at low risk was 25.6% in 2019. Read More

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A dynamic prediction score for obstetric anal sphincter injury among nulliparous women delivering vaginally.

Int J Gynaecol Obstet 2021 Apr 30. Epub 2021 Apr 30.

The Department of Obstetrics and Gynecology, Hadassah Medical Center, Jerusalem, Israel.

Objective: To develop a risk score for obstetric anal sphincter injury (OASI) occurrence among nulliparous women delivering vaginally, based on data available at admission for delivery and as labor progresses.

Methods: A retrospective study of all nulliparous women that delivered vaginally during 3/2011-1/2021. Characteristics were compared between OASI and no-OASI groups. Read More

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Use of Oral Contraceptives as a Potential Risk Factor for Breast Cancer: A Systematic Review and Meta-Analysis of Case-Control Studies Up to 2010.

Int J Environ Res Public Health 2021 Apr 27;18(9). Epub 2021 Apr 27.

Department of Medical Informatics and Statistics with E-learning Lab, Medical University, 20-090 Lublin, Poland.

Despite numerous studies evaluating the risk of breast cancer among oral contraception users, the effect of oral contraceptive on developing breast cancer remains inconclusive. Therefore, we conducted a systematic review of literature with meta-analysis in order to quantitative estimate this association. The bibliographic database MEDLINE and EMBASE, and reference lists of identified articles were searched, with no language restrictions, from the start of publication to August 2010. Read More

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Risk Factors for Postpartum Hemorrhage in a Thai-Myanmar Border Community Hospital: A Nested Case-Control Study.

Int J Environ Res Public Health 2021 Apr 27;18(9). Epub 2021 Apr 27.

Department of Family Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

Postpartum hemorrhage (PPH) is a common complication of pregnancy and a global public health concern. Even though PPH risk factors were extensively studied and reported in literature, almost all studies were conducted in non-Asian countries or tertiary care centers. Our study aimed to explore relevant risk factors for PPH among pregnant women who underwent transvaginal delivery at a Thai-Myanmar border community hospital in Northern Thailand. Read More

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Immune Milieu Established by Postpartum Liver Involution Promotes Breast Cancer Liver Metastasis.

Cancers (Basel) 2021 Apr 3;13(7). Epub 2021 Apr 3.

Department of Cell, Developmental, and Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA.

In rodents, we identified a physiologic process within the normal liver that creates a pre-metastatic niche. This physiology is weaning-induced liver involution, characterized by hepatocyte cell death, immune influx, and extracellular matrix remodeling. Here, using weaning-induced liver involution as a model of a physiologically regulated pro-metastatic niche, we investigate how liver involution supports breast cancer metastasis. Read More

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The effect of epidural analgesia on maternal-neonatal outcomes: a retrospective study.

Ginekol Pol 2021 Apr 29. Epub 2021 Apr 29.

Department of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizho, China.

Objectives: Epidural analgesia is commonly used for relieving labor pain incontemporary clinical practice. The rate of pregnant women who request epiduralanalgesia during labor has been increasing annually, leading to a debate on the effectof epidural analgesia on maternal or neonatal outcomes.

Material And Methods: The medical records of nulliparous women with a term singletonpregnancy from January to December 2019 at the Affiliated Hospital of ZunyiMedical University were retrospectively reviewed. Read More

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The risk of developing a meningioma during and after pregnancy.

Sci Rep 2021 Apr 28;11(1):9153. Epub 2021 Apr 28.

Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Pregnancy has been associated with diagnosis or growth of meningiomas in several case reports, which has led to the hypothesis that pregnancy may be a risk factor for meningiomas. The aim of this study was to test this hypothesis in a large population-based cohort study. Women born in Sweden 1958-2000 (N = 2,204,126) were identified and matched with the Medical Birth Register and the Cancer Register. Read More

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International gestational age-specific centiles for blood pressure in pregnancy from the INTERGROWTH-21st Project in 8 countries: A longitudinal cohort study.

PLoS Med 2021 Apr 27;18(4):e1003611. Epub 2021 Apr 27.

Critical Care Research Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford University Hospitals NHS Trust, NIHR Biomedical Research Centre, Oxford, United Kingdom.

Background: Gestational hypertensive and acute hypotensive disorders are associated with maternal morbidity and mortality worldwide. However, physiological blood pressure changes in pregnancy are insufficiently defined. We describe blood pressure changes across healthy pregnancies from the International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st) Fetal Growth Longitudinal Study (FGLS) to produce international, gestational age-specific, smoothed centiles (third, 10th, 50th, 90th, and 97th) for blood pressure. Read More

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Language Preference and Risk of Primary Cesarean Delivery: A Retrospective Cohort Study.

Matern Child Health J 2021 Apr 27. Epub 2021 Apr 27.

Harvard Medical School, Boston, MA, USA.

Objectives: While some medical indications for cesarean delivery are clear, subjective provider and patient factors contribute to the rising cesarean delivery rates and marked disparities between racial/ethnic groups. We aimed to determine the association between language preference and risk of primary cesarean delivery.

Methods: We conducted a retrospective cohort study of nulliparous, term, singleton, vertex (NTSV) deliveries of patients over 18 years old from 2011-2016 at an academic medical center, supplemented with data from the Massachusetts Department of Public Health. Read More

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Benign breast disease and changes in mammographic breast density.

Breast Cancer Res 2021 Apr 26;23(1):49. Epub 2021 Apr 26.

Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.

Background: Mammographic breast density (MBD) and benign breast disease (BBD) are two of the strongest risk factors for breast cancer. Understanding trends in MBD by age and parity in women with BBD is essential to the clinical management and prevention of breast cancer.

Methods: Using data from the Early Determinants of Mammographic Density (EDMD) study, a prospective follow-up study of women born in 1959-1967, we evaluated MBD in 676 women. Read More

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Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery?: Condensation: Ultrasound at the beginning of the active phase can predict length of labor and mode of delivery in nulliparous women.

Am J Obstet Gynecol MFM 2021 Apr 23:100383. Epub 2021 Apr 23.

National Center for Fetal Medicine, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway; Department of Obstetrics and Gynecology, Stavanger University Hospital, Stavanger, Norway; Institute of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Background: Identifying predictive factors for a normal outcome at admission in the labor ward would be of value for planning labor care, timing interventions and in preventing labor dystocia. Clinical assessments of fetal head station and position at the start of labor have some predictive value but the value of ultrasound methods for this purpose has not been investigated. Studies using transperineal ultrasound before labor onset show possibilities of using these methods to predict outcome. Read More

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Challenges in the Triage Care of Low-Risk Laboring Patients: A Comparison of 2 Models of Practice.

J Perinat Neonatal Nurs 2021 Apr-Jun 01;35(2):123-131

University of Maryland School of Nursing, Baltimore (Dr Breman and Mr Barr); Vanderbilt School of Nursing, Nashville, Tennessee (Dr Phillippi); School of Nursing and School of Medicine, Oregon Health and Science University, Portland (Dr Tilden); Perinatal Behavioral Health Clinic, Weymouth, Massachusetts (Dr Paul); and Emory University School of Nursing, Atlanta, Georgia (Dr Carlson).

Triage and the timing of admission of low-risk pregnant women can affect the use of augmentation, epidural, and cesarean. The purpose of this analysis was to explore these outcomes in a community hospital by the type of provider staffing triage. This was a retrospective cohort study of low-risk nulliparous women with a term, vertex fetus laboring in a community hospital. Read More

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Novel 3D MRI technique to measure perineal membrane structural changes with pregnancy and childbirth: Technique development and measurement feasibility.

Int Urogynecol J 2021 Apr 24. Epub 2021 Apr 24.

Department of Obstetrics and Gynecology, Michigan Medicine, Ann Arbor, MI, USA.

Introduction And Hypothesis: We aimed to develop and validate a new MRI-based perineal membrane reconstruction and morphological measurement technique, and test its feasibility on nulliparous and parous women to determine the effects of pregnancy and childbirth on the perineal membrane.

Methods: The perineal membrane was traced on high-resolution MRI using 3D Slicer® and analyses performed using Rhinoceros 6.0 SR23®. Read More

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The correlation between maternal age, parity, cardiac diastolic function and occurrence rate of pre-eclampsia.

Sci Rep 2021 Apr 23;11(1):8842. Epub 2021 Apr 23.

Department of Cardiology, NHFPC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Peking University Third Hospital, 49 Huayuan North Road, Haidian District, Beijing, 100191, China.

To evaluate the effect of age and parity on maternal cardiac diastolic function in second trimester among pregnant women with normal left ventricular ejection fraction. To analyze the correlation between impaired diastolic function and pre-eclampsia. It had been suggested that maternal cardiac adaptations during pregnancy differed between nulliparous and primiparous women and also varied according to age. Read More

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Updates on conservative management of endometrial cancer in patients younger than 45 years.

Gynecol Oncol 2021 Apr 20. Epub 2021 Apr 20.

Department of Gynecology and Obstetrics, Sanatorio Allende, Córdoba, Argentina.

Endometrial cancer is the most common gynecologic malignancy in developed country. Women under the age of 40 represent 5% of all endometrial cancer and the majority are nulliparous at the time of diagnosis. The aim of this review was to compare oncologic and fertility outcomes among different fertility-preserving therapies in patients under 45 years of age with grade 1 or 2 endometrial cancer. Read More

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Experiences with simultaneous use of contraception and the vaginal ring for HIV prevention in sub-Saharan Africa.

BMC Womens Health 2021 Apr 23;21(1):175. Epub 2021 Apr 23.

Women's Global Health Imperative, RTI International, San Francisco, CA, USA.

Background: Clinical trials have found that a monthly dapivirine vaginal ring was well-tolerated and reduced HIV-1 risk among women in sub-Saharan Africa. However, in order for the ring or other novel prevention methods to have optimal impact, it is necessary to understand and address women's challenges to uptake and adherence. This paper provides insight into a few key challenges noted by women using the ring and contraceptives simultaneously. Read More

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Delayed versus early pushing during the second stage of labour in primigravidas under epidural anaesthesia with occipitoposterior malposition: a randomised controlled study.

J Obstet Gynaecol 2021 Apr 23:1-5. Epub 2021 Apr 23.

Obstetrics and Gynecology Department, Kasr AlAini Hospital, Cairo University, Cairo, Egypt.

This randomised controlled trial aimed to compare the effect of early and delayed pushing during the second stage of labour in women with occipitoposterior (OP) malposition. It included 184 nulliparous women with OP position randomised to early pushing in which women were allowed to push within one hour after full cervical dilatation or delayed pushing in which women were asked not to push for maximum of three hours or start pushing when the vertex was visible. The primary outcome was successful vaginal delivery. Read More

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Prelabor cesarean section: the role of advanced maternal age and associated factors.

Rev Saude Publica 2021 14;55. Epub 2021 Apr 14.

Universidade Federal do Espírito Santo. Departamento de Medicina Social. Vitória, ES, Brasil.

Objective: to evaluate whether advanced maternal age (AMA) is associated with prelabor cesarean section and to identify the factors associated with prelabor cesarean section in AMA women, according to the mode of type of labor financing (private or public).

Methods: Based on the Birth in Brazil survey, the research was conducted on representative sample of mothers for the country (Brazil), regions, type of hospital and location (capital or not), in 2011/2012. This study included 15,071 women from two age groups: 20-29 years and ≥ 35 years. Read More

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Impact of fertility concerns on endocrine therapy decisions in young breast cancer survivors.

Cancer 2021 Apr 22. Epub 2021 Apr 22.

Dana-Farber Cancer Institute, Boston, Massachusetts.

Background: The diagnosis and treatment of breast cancer can have profound effects on a young woman's family planning and fertility, particularly among women with hormone receptor-positive breast cancer.

Methods: The Young Women's Breast Cancer Study was a multicenter cohort of women aged 40 years or younger and newly diagnosed with breast cancer from 2006 to 2016. Surveys included assessments of fertility concerns, endocrine therapy (ET) preferences, and use. Read More

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Intimate partner violence and child outcomes at age 10: a pregnancy cohort.

Arch Dis Child 2021 Apr 21. Epub 2021 Apr 21.

Intergenerational Health Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

Objective: Assess the mental health, physical health, cognitive and language development of 10-year old children in families where mothers have reported intimate partner violence (IPV) compared with children with no reported IPV exposure.

Design: Prospective pregnancy cohort. Maternal report of IPV (Composite Abuse Scale) at 1, 4 and 10 years. Read More

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Longitudinal changes in HDL-cholesterol concentration are associated with different risk factors in primiparous and nulliparous young women: The NHLBI Growth and Health Study (NGHS).

J Clin Lipidol 2021 Mar 17. Epub 2021 Mar 17.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States. Electronic address:

Background: Previous studies report that first pregnancy is associated with persistent decreases in HDL-cholesterol (HDL-C) concentrations.

Objective: This study evaluated factors associated with declines in HDL-C concentration in parous and nulliparous young women.

Methods: This study leverages data from African-American and white women from the NHLBI Growth and Health Study. Read More

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