9,471 results match your criteria november 2008


Minimum five-year outcomes of reverse total shoulder arthroplasty using a trabecular metal glenoid base plate.

Bone Joint J 2021 Aug;103-B(8):1333-1338

University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby, UK.

Aims: Reverse total shoulder arthroplasty (RTSA) using trabecular metal (TM)-backed glenoid implants has been introduced with the aim to increase implant survival. Only short-term reports on the outcomes of TM-RTSA have been published to date. We aim to present the seven-year survival of TM-backed glenoid implants along with minimum five-year clinical and radiological outcomes. Read More

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The additional use of methylene blue has a decatecholaminisation effect on cardiac vasoplegic syndrome after cardiac surgery.

J Cardiothorac Surg 2021 Jul 28;16(1):205. Epub 2021 Jul 28.

Department of Anesthesiology, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.

Background: Postoperative vasoplegia with minimal responsiveness to vasopressors is common after cardiac surgery. Called cardiac vasoplegic syndrome (CVS), it is caused by multiple factors. Treating CVS involves a high dose of fluids and catecholamines, however high doses of catecholamines and fluids are associated with serious side effects. Read More

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Round window anatomy predicts ease of cochlear implantation in children.

Int J Pediatr Otorhinolaryngol 2021 Jul 21;149:110852. Epub 2021 Jul 21.

Division of Pediatric Otolaryngology, Children's National Health System, Washington, DC, USA. Electronic address:

Objectives: We aim to evaluate the utility of the Round Window Angle (RWA) as a predictor of difficulty and operative time in cochlear implantation.

Methods: A retrospective study of pediatric patients that underwent cochlear implantation and CT temporal bone imaging from January 2008 to November 2019. Correlation, univariate, and multivariate analysis were conducted. Read More

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Clinical trials proposed for the VA Cooperative Studies Program: Success rates and factors impacting approval.

Contemp Clin Trials Commun 2021 Sep 9;23:100811. Epub 2021 Jul 9.

Cooperative Studies Program, Office of Research and Development, Veterans Health Administration, Washington DC, 20420, USA.

The process by which funding organizations select among the myriad number of proposals they receive is a matter of significant concern for researchers and the public alike. Despite an extensive literature on the topic of peer review and publications on criteria by which clinical investigations are reviewed, publications analyzing peer review and other processes leading to government funding decisions on large multi-site clinical trials proposals are sparse. To partially address this gap, we reviewed the outcomes of scientific and programmatic evaluation for all letters of intent (LOIs) received by the Department of Veterans Affairs (VA) Cooperative Studies Program (CSP) between July 4, 2008, and November 28, 2016. Read More

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September 2021

Modified Craniocervical Approach for Resection of the Styloid Process in Patients with Eagle's Syndrome.

J Neurol Surg B Skull Base 2021 Jul 21;82(Suppl 3):e179-e183. Epub 2019 Nov 21.

Department of Neurological Surgery, Neurological Institute of Curitiba, Curitiba, Paraná, Brazil.

 Surgical treatment of Eagle's syndrome remains the mainstay of treatment. Palsy of the marginal mandibular branch of the facial nerve is the most significant complication encountered in transcervical resections, due to direct compression during the approach. We proposed a modification of the craniocervical approach to the jugular foramen to resect the styloid process avoiding the marginal mandibular branch and subsequent palsy. Read More

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Dynamics of Invasive Pneumococcal Disease in Israel in Children and Adults in the PCV13 Era: A Nationwide Prospective Surveillance.

Clin Infect Dis 2021 Jul 22. Epub 2021 Jul 22.

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Background: Following 13-valent pneumococcal conjugate vaccine (PCV13) implementation in infants worldwide, overall and vaccine-type invasive pneumococcal disease (IPD) rates declined in children, with variable indirect impact on adults.

Methods: A population-based, prospective, nationwide active surveillance of IPD in Israel, 2004-2019 (for adults ≥18 years, 2009-2019). The 7-valent PCV (PCV7)/PCV13 were implemented in Israel in July 2009/November 2010, respectively, with >90% uptake in children <2 years. Read More

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Association between Net Ultrafiltration Rate and Renal Recovery among Critically Ill Adults with Acute Kidney Injury Receiving Continuous Renal Replacement Therapy: An Observational Cohort Study.

Blood Purif 2021 Jul 21:1-13. Epub 2021 Jul 21.

Department of Intensive Care Medicine, Austin Hospital, The University of Melbourne, Parkville, Victoria, Australia.

Introduction: Higher net ultrafiltration (UFNET) rates are associated with mortality among critically ill patients with acute kidney injury (AKI) and treated with continuous renal replacement therapy (CRRT).

Objective: The aim of the study was to discover whether UFNET rates are associated with renal recovery and independence from renal replacement therapy (RRT).

Methods: Retrospective cohort study using data from the Randomized Evaluation of Normal versus Augmented Level of Renal Replacement Therapy trial that enrolled 1,433 critically ill patients with AKI and treated with CRRT between December 2005 and November 2008 across 35 intensive care units in Australia and New Zealand. Read More

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Preoperative diagnosis of BRCA1/2 mutation impacts decision-making for risk-reducing mastectomy in breast cancer patients.

Sci Rep 2021 Jul 20;11(1):14747. Epub 2021 Jul 20.

Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.

Decision to undergo risk-reducing mastectomy (RRM) needs to consider several factors, including patient's preference, surgeon's preference, family history, and genetic predisposition. The aim of this study was to examine whether preoperative diagnosis of BRCA1/2 mutation status could influence surgical decision-making in newly diagnosed breast cancer patients. We retrospectively reviewed ipsilateral breast cancer patients with BRCA1/2 mutation who underwent primary surgery between January 2008 and November 2019 at a single institution in Korea. Read More

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Surgical Management of Axilla Following Neoadjuvant Endocrine Therapy.

Ann Surg Oncol 2021 Jul 17. Epub 2021 Jul 17.

Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA.

Background: Randomized clinical trials support deescalation of axillary surgery in breast cancer patients with low-volume axillary disease treated with a surgery-first approach. However, few data exist to guide axillary surgery following neoadjuvant endocrine therapy (NET). Therefore, we evaluated the extent and outcomes of axillary surgery in a contemporary cohort of NET patients, a treatment approach that has become particularly relevant during the coronavirus disease-19 (COVID-19) pandemic. Read More

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Room for Improvement: The Trephination Procedure for Pediatric Patients with Pilonidal Disease.

J Surg Res 2021 Jul 12;267:605-611. Epub 2021 Jul 12.

Department of Pediatric Surgery, Nationwide Children's Hospital, Columbus, OH; The Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, OH. Electronic address:

Background: Pilonidal disease is common amongst adolescent males and females and often leads to recurrent symptoms and life-altering morbidity. The traditional surgical approach includes wide excision of the involved area and carries a high rate of postoperative morbidity. A minimally invasive surgical approach using trephines was described by Gips in 2008 and has since been widely adopted by many surgeons. Read More

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Impact of Musculoskeletal Limitations on Cardiac Rehabilitation Participation.

Front Cardiovasc Med 2021 28;8:688483. Epub 2021 Jun 28.

Cardiovascular Rehabilitation Program, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States.

To help clarify a potential barrier to cardiac rehabilitation (CR) participation we sought to examine the association between musculoskeletal limitations (MSLs) and CR enrollment and participation. Consecutive CR eligible individuals hospitalized for a cardiac event (myocardial infarction, percutaneous coronary intervention, and/or coronary artery bypass graft) between the months of November 2007 and May 2008, were asked to complete a mailed survey within 2 weeks after hospital discharge, assessing demographic factors, Patient Health Questionnaire (PHQ-9), participation in CR and MSLs through a validated MSLs screening tool. CR enrollment rates were compared between patients with and without MSLs. Read More

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Predictors of Type 2 Diabetes Mellitus Remission After Metabolic Surgery in Asian Patients with a BMI < 32.5 kg/m.

Obes Surg 2021 Jul 5. Epub 2021 Jul 5.

Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha, China.

Background: Metabolic surgery is an effective treatment for type 2 diabetes mellitus (T2DM) in patients with obesity. However, the efficacy in patients with body mass index (BMI) < 32.5 kg/m, especially in Asian populations, has not been widely reported, and there are few studies on the prediction of diabetes remission. Read More

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Attenuating the Variability of Lipids Is Beneficial for the Hypertension Management to Reduce the Cardiovascular Morbidity and Mortality in Older Adults.

Front Cardiovasc Med 2021 17;8:692773. Epub 2021 Jun 17.

Basic Medical College, Shandong First Medical University, Jinan, China.

To investigate the beneficial of attenuating the variability of lipids to the hypertension management in older adults. Between April 2008 and November 2010, 1,244 hypertensive patients aged ≥60 years were recruited and randomized into placebo and rosuvastatin groups. Outcomes and inter-visit plasma lipids variability were assessed. Read More

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Bevacizumab in First-Line Chemotherapy Improves Progression-Free Survival for Advanced Ovarian Clear Cell Carcinoma.

Cancers (Basel) 2021 Jun 25;13(13). Epub 2021 Jun 25.

Department of Gynecology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan.

(1) Background: We investigated survival outcomes following first-line chemotherapy before and after approval of bevacizumab (Bev) for ovarian cancer in Japan to evaluate the efficacy of Bev for advanced clear cell carcinoma (CCC). (2) Methods: We investigated 28 consecutive patients diagnosed with CCC (stages III/IV) at our hospital between 2008 and 2018. Bev was administered for treatment of advanced CCC after approval in Japan in November 2013. Read More

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A South American Experience With Postoperative Complications Following Chest Wall Reconstruction for Neoplasms.

World J Surg 2021 Jun 27. Epub 2021 Jun 27.

Research Department, Instituto Nacional de Cancerología, Calle 1 No. 9-85, Bogotá, 111511, Colombia.

Background: This study aims to report postoperative complications of chest wall reconstructions due to resections of primary or secondary neoplasms in a South American cancer institution and their association with prosthesis reconstruction.

Materials And Methods: We retrospectively reviewed clinical records of patients with primary or secondary chest wall neoplasms who underwent resection and reconstruction between November 2008 and October 2018 at the Instituto Nacional de Cancerología, Bogota, Colombia.

Results: A total of 77 patients were analyzed, 50 were women (64. Read More

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Laparoscopic Radical Hysterectomy Results in Higher Recurrence Rate Versus Open Abdominal Surgery for Stage IB1 Cervical Cancer Patients With Tumor Size Less Than 2 Centimeter: A Retrospective Propensity Score-Matched Study.

Front Oncol 2021 10;11:683231. Epub 2021 Jun 10.

Department of Gynecology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Objective: To compare the oncologic outcomes between laparoscopic and open radical hysterectomy in patients with stage IB1 cervical cancer lesion less than 2 cm.

Methods: Patients diagnosed FIGO (2009) stage IB1 (tumor diameter <2 cm) and underwent radical hysterectomy in our hospital between March 2008 and November 2018 were studied. A propensity-matched comparison (1:2) was conducted to minimize selection biases. Read More

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Determination of reactivation rate and risk factors for Hepatitis B virus reactivation in low-positive cases: A retrospective cohort study.

J Infect Chemother 2021 Jun 24. Epub 2021 Jun 24.

Department of Medical Oncology, Sapporo Medical University School of Medicine, Sapporo, Japan.

Introduction: In quantitative assays for hepatitis B virus (HBV) DNA, although the amplification reaction signal is detected for low-positive cases, quantification remains challenging. HBV reactivation has been reported in many studies, but only a few have focused on HBV low-positive cases. This study aimed to determine the reactivation rate and risk factors for HBV reactivation in low-positive cases. Read More

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Global uncertainties and portfolio flow dynamics of the BRICS countries.

Res Int Bus Finance 2020 Dec 3;54:101277. Epub 2020 Jul 3.

Central Bank of the Republic of Turkey, Ankara, Turkey.

This paper investigates the dynamics of bond and stock market capital flows to BRICS countries under uncertainties such as global economic policy uncertainty and the US trade policy uncertainty. We use a time-varying Granger causality framework over the January 2008-November 2019 period to analyze the predictive power of uncertainties on capital flows in the form of bond and equity. The results show that the effects are heterogeneous across countries and stronger during the Global Financial Crisis period and post-2018 period while it lost its significance in the subsequent period. Read More

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December 2020

Prognostic Implications of Treatment Delays for Patients with Non-muscle-invasive Bladder Cancer.

Eur Urol Focus 2021 Jun 22. Epub 2021 Jun 22.

Service d'Urologie et Chirurgie de la Transplantation, Hospices Civils de Lyon, Lyon, France; Université Claude Bernard-Lyon 1, Lyon, France.

Background: Delay in treatment is a prognostic factor in muscle-invasive bladder cancer.

Objective: To evaluate clinical outcomes associated with delays in diagnosis and treatment for patients with non-muscle invasive bladder cancer (NMIBC).

Design, Setting, And Participants: In this retrospective study we analyzed data for patients treated at our center between November 2008 and December 2016 for intermediate risk (IR) or high risk (HR) NMIBC with an additional intravesical treatment. Read More

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Fitness vs. fatness as determinants of survival in non-institutionalized older adults: The EXERNET multi-center study.

J Gerontol A Biol Sci Med Sci 2021 Jun 21. Epub 2021 Jun 21.

GENUD (Growth, Exercise, NUtrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain.

Background: Physical fitness and body composition are important health indicators, nevertheless their combined pattern inter-relationships and their association with mortality are poorly investigated.

Methods: This longitudinal study is part of the Spanish EXERNET-Elder project. Person-months follow-up were calculated from the interview date, performed between June 2008 and November 2009, until date of death or censoring on March 2018 (whichever came first). Read More

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Prognostic effect of gender on outcome of treatment for adults with acute myeloid leukaemia.

Br J Haematol 2021 Jul 17;194(2):309-318. Epub 2021 Jun 17.

Mayo Clinic, Rochester, MN, USA.

There are conflicting reports in the literature suggesting that one gender or the other has a better survival with acute myeloid leukaemia (AML). The present study was done in an attempt to resolve the issue. The effect of gender was examined on 3546 newly diagnosed patients with AML, including 548 patients with acute promyelocytic leukaemia (APL) enrolled in 10 multi-institutional treatment studies from March 1984 to November 2008. Read More

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Angiostrongylus vasorum in foxes () and wolves ( italicus) from Abruzzo region, Italy.

Int J Parasitol Parasites Wildl 2021 Aug 20;15:184-194. Epub 2021 May 20.

Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale" (IZSAM), Campo Boario, 64100, Teramo, Italy.

In Europe wildlife animals such as the red fox () are considered the main reservoir for as well as a potential threat for domestic dog infection. Though this parasite is endemic in fox populations, data on infection in wolves () are still scant, having only recently been described in Northwestern Spain, in Italy, in Croatia and in Slovakia. Based on the rising number of cases of canine lungworm infection in Central Italy (Abruzzo region), the aim of the present study was to investigate the infection by in fox and wolf populations sharing the same geographical area of dogs. Read More

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Current developments in delivering customized care: a scoping review.

BMC Health Serv Res 2021 Jun 13;21(1):575. Epub 2021 Jun 13.

MOS (EA 7418), French School of Public Health, Rennes, France.

Background: In recent years, there has been a growing interest in health care personalization and customization (i.e. personalized medicine and patient-centered care). Read More

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Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care.

BMC Pulm Med 2021 Jun 9;21(1):196. Epub 2021 Jun 9.

Translational Healthcare Technologies Group, Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.

Background: Ventilator-associated pneumonia (VAP) is an important diagnosis in critical care. VAP research is complicated by the lack of agreed diagnostic criteria and reference standard test criteria. Our aim was to review which reference standard tests are used to evaluate novel index tests for suspected VAP. Read More

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A Novel Multiparameter Scoring Model for Noninvasive Early Prediction of Ischemic Colitis: A Multicenter, Retrospective, and Real-World Study.

Clin Transl Gastroenterol 2021 Jun 9;12(6):e00370. Epub 2021 Jun 9.

Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Introduction: Ischemic colitis (IC) is a common gastrointestinal ischemic disease caused by hypoperfusion or reperfusion injury. However, there are few studies on risk factors associated with poor prognoses of the disease. This study aimed to determine the predictors of poor prognoses in patients with IC and establish a prognostic scoring method with good internal and external validity for identifying severe cases in an early stage. Read More

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Physical assessment skills taught in nursing curricula: a scoping review.

JBI Evid Synth 2021 Jun 7. Epub 2021 Jun 7.

Faculty of Nursing, University of Windsor, Windsor, ON, Canada Queen's Collaboration for Health Care Quality: A JBI Centre of Excellence, Kingston, ON, Canada Leddy Library, University of Windsor, Windsor, ON, Canada.

Objective: This scoping review sought to establish the current state of knowledge regarding physical assessment skills taught globally in undergraduate nursing curricula. Explicitly, which skills are being taught via curricula, and which skills are performed by students in clinical placements. Additionally, what physical assessment skills are being used by registered nurses in practice. Read More

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Cohort study of ageing from Bagé (SIGa-Bagé), Brazil: profile and methodology.

BMC Public Health 2021 06 7;21(1):1089. Epub 2021 Jun 7.

Post-Graduate Programme in Nursing, Federal University of Pelotas, Pelotas, Brazil.

Background: The Bagé Cohort Study of Ageing is a population-based cohort study that has recently completed the first follow-up of a representative sample of older adults from Bagé, a city with more than 100,000 inhabitants located in the state of Rio Grande do Sul, Brazil. This is one of the first longitudinal studies to assess the impact of primary health care coverage on health conditions and inequalities. Our aim is to investigate the prevalence, incidence and trends of risk factors, health behaviours, social relationships, non-communicable diseases, geriatric diseases and disorders, hospitalisation, self-perceived health, and all-cause and specific-cause mortality. Read More

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Induction Chemotherapy Combined With Intensity-Modulated Radiotherapy for 129 Nasopharyngeal Carcinoma Patients With Synchronous Metastases: A Retrospective Study.

Front Oncol 2021 21;11:654871. Epub 2021 May 21.

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.

Objective: To analyze the therapeutic effect and prognostic factors of nasopharyngeal carcinoma (NPC) patients with distant metastases at initial diagnosis receiving induction chemotherapy with intensity-modulated radiotherapy (IMRT).

Methods: A total of 129 patients who underwent platinum-based induction chemotherapy followed by definitive IMRT with or without concurrent or adjuvant chemotherapy for newly diagnosed distant metastatic NPC in our center between March 2008 and November 2018 were retrospectively analyzed. 41 patients underwent local therapy for metastatic sites. Read More

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Prevalence of hypertrophic cardiomyopathy in a large sample of the Spanish working population.

Rev Clin Esp (Barc) 2021 Jun-Jul;221(6):315-322. Epub 2021 Mar 10.

UGC Área del Corazón, Servicio de Cirugía Cardiovascular y Cardiología, Hospital Universitario Virgen de la Victoria, Málaga, Spain; Instituto Biosanitario de Málaga (IBIMA), Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (FIMABIS), Universidad de Málaga, Málaga, Spain.

Background And Objectives: To date, in Spain, there are no studies that have evaluated the prevalence of hypertrophic cardiomyopathy in the general population. The aim of this study was to assess the prevalence of hypertrophic cardiomyopathy in a large sample of the working population of Spain.

Materials And Methods: The study included 13,179 workers (73% men; mean age: 40 years) from 5 regions of Spain who, between May 2008 and November 2010, had a medical examination with an electrocardiogram. Read More

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Impact of Modified Anesthesia Management for Pediatric Patients With Williams Syndrome.

J Cardiothorac Vasc Anesth 2021 Apr 20. Epub 2021 Apr 20.

Division of Pediatric Cardiac Anesthesia, Lucile Packard Children's Hospital Stanford and Stanford University School of Medicine, Palo Alto, CA.

Objective: This study compared the percent change in systolic blood pressure and the incidence of adverse cardiac events (ACEs; defined as cardiac arrest, cardiopulmonary resuscitation, arrhythmias, or ST-segment changes) during anesthesia induction in patients with Williams syndrome (WS) before and after implementation of a perioperative management strategy.

Design: Retrospective observational cohort study.

Setting: Single quaternary academic referral center. Read More

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