G3 (Bethesda) 2017 08 7;7(8):2845-2854. Epub 2017 Aug 7.
Pacific Northwest Research Institute, Seattle, Washington 98122
Biofilm formation by microorganisms is a major cause of recurring infections and removal of biofilms has proven to be extremely difficult given their inherent drug resistance . Understanding the biological processes that underlie biofilm formation is thus extremely important and could lead to the development of more effective drug therapies, resulting in better infection outcomes. Using the yeast as a biofilm model, overexpression screens identified , , , , , and as regulators of biofilm formation. Read More