594 results match your criteria nitrite scavenging


Cerebroprotective effect of pterostilbene against global cerebral ischemia in rats.

Heliyon 2021 May 20;7(5):e07083. Epub 2021 May 20.

Department of Clinical Pharmacy, Prince Sattam Bin Abdul Aziz University, Al-Kharj, Saudi Arabia.

Aim Of The Study: The role of pterostilbene against induced neurobehavioral alterations in global cerebral ischemia-reperfusion and oxidative damage was studied.

Materials And Methods: Male SD rats (180-200 g) were exposed for 30 min to bilateral carotid artery occlusion accompanied by 60 min reperfusion to cause cerebral injury. Pretreatment with pterostilbene (200 and 400 mg/kg, orally) was given to the animals for ten days followed by ischemia-reperfusion injury. Read More

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Evaluation of Quality Characteristics of Low-Nitrite Pork Sausages with Paprika Oleoresin Solution during Refrigerated Storage.

Food Sci Anim Resour 2021 May 1;41(3):428-439. Epub 2021 May 1.

Department of Animal Science, Chonnam National University, Gwangju 61186, Korea.

The objective of this study was to evaluate quality characteristics of pork emulsified-sausage (ES) containing paprika oleoresin solution (POS) as a replacement for sodium nitrite (NaNO) during refrigerated storage. ESs were prepared with four treatments: 1) REF, 150 ppm NaNO; 2) CTL, 75 ppm NaNO; 3) TRT1, 75 ppm NaNO+0.1% POS (1% paprika oleoresin+99% sunflower seed oil); and 4) TRT2, 75 ppm NaNO+0. Read More

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How does the pre-treatment of landfill leachate impact the performance of O and O/UVC processes?

Chemosphere 2021 Sep 29;278:130389. Epub 2021 Mar 29.

Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM), Departamento de Engenharia Química, Faculdade de Engenharia da Universidade Do Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal. Electronic address:

In this study, O and O/UVC processes were evaluated for the treatment of landfill leachate after biological nitrification/denitrification, coagulation, or their combinations. The O-driven stage efficiency was assessed by the removal of color, organic matter (dissolved organic carbon (DOC) and chemical oxygen demand (COD)), and biodegradability increase (Zahn-Wellens test). Also, fluorescence excitation-emission matrix (EEM) and size exclusion chromatography coupled with OC detector (SEC-OCD) analysis were carried out for each strategy. Read More

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September 2021

BiO nanosheets arrays in-situ decorated on carbon cloth for efficient electrochemical reduction of nitrate.

Chemosphere 2021 Sep 29;278:130386. Epub 2021 Mar 29.

National Engineering Research Center for Industry Crystallization Technology,School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China; Co-Innovation Center of Chemical Science and Engineering, Tianjin, 300072, China; School of Chemical Engineering and Technology, Hainan University, Haikou, 570228, China. Electronic address:

Excessive nitrate in industrial wastewater is still an important environmental protection issue for human beings. As nitrate promoter metal, Sn has been extensively studied in nitrate reduction reaction (NITRR). However, it suffers from high selectivity of nitrite as the final product at times. Read More

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September 2021

Red blood cells from patients with pre-eclampsia induce endothelial dysfunction.

J Hypertens 2021 Mar 1. Epub 2021 Mar 1.

Department of Physiology and Pharmacology Department of Clinical Sciences, Karolinska Institutet Department of Obstetrics and Gynecology, Danderyd Hospital, Stockholm, Sweden.

Rationale: Pre-eclampsia is a multisystem disorder associated with systemic vascular dysfunction and decreased nitric oxide (NO) bioactivity. Arginase competes with NO synthase (NOS) for L-arginine, and its upregulation may reduce NOS-derived NO formation or induce production of reactive oxygen species (ROS) via uncoupling of NOS, resulting in endothelial dysfunction. Red blood cells (RBCs) have emerged as key players in NO homeostasis via their interactions with the endothelium. Read More

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Anti-inflammatory Activity of Mollugo cerviana Methanolic Extract in LPS-induced Acute Inflammatory RAW 264.7 Macrophages.

Comb Chem High Throughput Screen 2021 Mar 1. Epub 2021 Mar 1.

Department of Biochemistry, University of Kerala, Kariavattom campus, Thiruvananthapuram, Kerala 695581. India.

Background: The management of acute inflammation, which arises from complex biological responses to harmful stimuli, is an important determinant in recovery of the system from an otherwise detrimental outcome such as septicemia. However, the side effects and limitations of current therapeutics necessitate the development of newer and safer alternatives. Mollugo cerviana is a common medicinal herb of the Indian subcontinent and has been traditionally used for its fever mitigating, anti-microbial and hepatoprotective action. Read More

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Novel Pathway for Vanadium(V) Bio-Detoxification by Gram-Positive .

Environ Sci Technol 2021 02 25;55(3):2121-2131. Epub 2021 Jan 25.

School of Water Resources and Environment, MOE Key Laboratory of Groundwater Circulation and Environmental Evolution, China University of Geosciences (Beijing), Beijing 100083, P. R. China.

Whereas prospects of bioremediation for a vanadium(V) [V(V)]-contaminated environment are widely recognized, reported functional species are extremely limited, with the vast majority of Gram-negative bacteria in Proteobacteria. Herein, the effectiveness of V(V) reduction is proved for the first time by , a Gram-positive bacterium in Firmicutes. The V(V) removal efficiency was 86. Read More

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February 2021

Non-denitrifier nitrous oxide reductases dominate marine biomes.

Environ Microbiol Rep 2020 12 10;12(6):681-692. Epub 2020 Sep 10.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, 59717, USA.

Microbial enzymes often occur as distinct variants that share the same substrate but differ in substrate affinity, sensitivity to environmental conditions, or phylogenetic ancestry. Determining where variants occur in the environment helps identify thresholds that constrain microbial cycling of key chemicals, including the greenhouse gas nitrous oxide (NO). To understand the enzymatic basis of NO cycling in the ocean, we mined metagenomes to characterize genes encoding bacterial nitrous oxide reductase (NosZ) catalyzing NO reduction to N. Read More

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December 2020

Toxic effects of naturally-aged microplastics on zebrafish juveniles: A more realistic approach to plastic pollution in freshwater ecosystems.

J Hazard Mater 2021 04 13;407:124833. Epub 2020 Dec 13.

Post-graduation Program in Biotechnology and Biodiversity, Goiano Federal Institution and Federal University of Goiás, Goiás, Brazil; Biological Research Laboratory, Post-graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute - Urata Campus, Goiás, Brazil. Electronic address:

We aim at evaluating the toxicity of naturally-aged polystyrene microplastics (MPs) in Danio rerio at intermediate development stage. Animal models were stactically exposed to 4 × 10 and 4 × 10 microparticles/m for five days - this concentration is environmentally relevant. We evaluated MP's impact on animals' nutritional status and REDOX balance, as well as its potential neuro- and cytotoxic action on them. Read More

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The Possibility of Reduction of Synthetic Preservative E 250 in Canned Pork.

Foods 2020 Dec 15;9(12). Epub 2020 Dec 15.

Department of Animal Raw Materials Technology, Faculty of Food Science and Biotechnology, University of Life Sciences in Lublin, Skromna 8 Street, 20-704 Lublin, Poland.

The purpose of this study was to determine the possibility of reducing the amount of NaNO added to canned pork during 180 days of storage. In this study, three variants of canned pork were prepared by adding different amounts of sodium nitrite: N (100 mg/kg), NH (50 mg/kg), and NF (no nitrite). The antioxidant capacity, amount of secondary products of lipid oxidation, color intensity, and pH were analyzed after one, 60, 90, and 180 days of storage where sensory properties, water activity (a), selected pathogenic bacteria, nitrate and nitrite residues, -nitrosamines (NA), and cholesterol were analyzed after 1 and 180 days of storage. Read More

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December 2020

Acetaminophen degradation by a synergistic peracetic acid/UVC-LED/Fe(II) advanced oxidation process: Kinetic assessment, process feasibility and mechanistic considerations.

Chemosphere 2021 Jan 27;263:128119. Epub 2020 Aug 27.

Department of Environmental Health Engineering, Abadan Faculty of Medical Sciences, Abadan, Iran.

Application of peracetic acid (PAA) in Advanced Oxidation Processes (AOPs) has seen an increase in the last few years. In this study, PAA/UVC-LED/transition metal was used to degrade acetaminophen (ACT) in an aqueous solution. Amongst tested transition metals (Fe, Cu, Co, Mn, Ag), Fe(II) demonstrated the highest efficiency. Read More

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January 2021

Probiotic Properties of LB5 Isolated from Kimchi Based on Nitrate Reducing Capability.

Foods 2020 Nov 30;9(12). Epub 2020 Nov 30.

Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul 05029, Korea.

The purpose of this study was to investigate the probiotic properties of lactic acid bacteria isolated from Korean radish water kimchi (dongchimi). A total of 800 isolates of lactic acid bacteria were isolated from kimchi, and the strain having reduction and tolerance capability for nitrate and nitrite was selected and identified as LB5 (LPLB5) by 16S rRNA sequencing. LPLB5 showed higher tolerance to acidic pH values (pH 2. Read More

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November 2020

Red Blood Cells as a "Central Hub" for Sulfide Bioactivity: Scavenging, Metabolism, Transport, and Cross-Talk with Nitric Oxide.

Antioxid Redox Signal 2020 12;33(18):1332-1349

Myocardial Infarction Research Laboratory, Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.

Sulfide was revealed to be an endogenous signaling molecule regulating a plethora of cellular functions. It is involved in the regulation of fundamental processes, including blood pressure regulation, suspended animation, and metabolic activity of mitochondria, pain, and inflammation. The underlying biochemical pathways and pharmacological targets are still largely unidentified. Read More

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December 2020

Anti-Inflammatory, Barrier-Protective, and Antiwrinkle Properties of Kuntze in Human Epidermal Keratinocytes.

Biomed Res Int 2020 26;2020:1759067. Epub 2020 Oct 26.

R & D Center, Shebah Biotech Inc., G-Tech Village, Chuncheon 24398, Republic of Korea.

This work aimed to assess the skin-beneficial properties of Kuntze, an herbal medication used to treat different types of disorders in traditional folk medicine. The total phenolic compounds and total antiradical, nitrite scavenging, superoxide scavenging, antielastase, and antihyaluronidase activities of a hot water extract of Kuntze leaves (ARE) were spectrophotometrically determined. Intracellular reactive oxygen species (ROS) was fluorometrically quantitated using 2',7'-dichlorodihydrofluorescein diacetate (DCFH-DA). Read More

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Naringenin induces tolerance to salt/osmotic stress through the regulation of nitrogen metabolism, cellular redox and ROS scavenging capacity in bean plants.

Plant Physiol Biochem 2020 Dec 1;157:264-275. Epub 2020 Nov 1.

Ege University, Faculty of Science, Department of Biology, Bornova, 35100, Izmir, Turkey. Electronic address:

The present study was conducted to uncover underlying possible effect mechanisms of flavonoid naringenin (Nar, 0.1-0.4 mM) in nitrogen assimilation, antioxidant response, redox status and the expression of NLP7 and DREB2A, on salt (100 mM NaCl) and osmotic-stressed (10% Polyethylene glycol, -0. Read More

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December 2020

Microbial community successions and their dynamic functions during harmful cyanobacterial blooms in a freshwater lake.

Water Res 2020 Oct 11;185:116292. Epub 2020 Aug 11.

Civil & Environmental Engineering, University of Utah, 110 S. Central Campus Drive, 2000 MCE, Salt Lake City, UT 84121, USA. Electronic address:

The current study reports the community succession of different toxin and non-toxin producing cyanobacteria at different stages of cyanobacterial harmful algal blooms (CyanoHABs) and their connectivity with nitrogen and phosphorus cycles in a freshwater lake using an ecogenomics framework. Comprehensive high throughput DNA sequencing, water quality parameter measurements, and functional gene expressions over temporal and spatial scales were employed. Among the cyanobacterial community, the lake was initially dominated by Cyanobium during the months of May, June, and early July, and later primarily by Aphanizomenon and Dolichospermum depicting functional redundancy. Read More

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October 2020

Myoglobin promotes nitrite-dependent mitochondrial S-nitrosation to mediate cytoprotection after hypoxia/reoxygenation.

Nitric Oxide 2020 11 4;104-105:36-43. Epub 2020 Sep 4.

Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, 15261, USA; Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, 15261, USA. Electronic address:

It is well established that myoglobin supports mitochondrial respiration through the storage and transport of oxygen as well as through the scavenging of nitric oxide. However, during ischemia/reperfusion (I/R), myoglobin and mitochondria both propagate myocardial injury through the production of oxidants. Nitrite, an endogenous signaling molecule and dietary constituent, mediates potent cardioprotection after I/R and this effect relies on its interaction with both myoglobin and mitochondria. Read More

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November 2020

Cashew ( L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema.

Antioxidants (Basel) 2020 Jul 24;9(8). Epub 2020 Jul 24.

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy.

Background: L. is a medicinal plant with powerful anti-oxidative and anti-inflammatory properties. Acute inflammatory events cause tissue alterations, decrease of anti-oxidative endogenous enzymes such as superoxide dismutase, catalase and glutathione, neutrophils infiltration, increase in the activities of myeloperoxidase, malondialdehyde, and pro-inflammatory release. Read More

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Antioxidant, DNA damage protective, antibacterial activities and nitrite scavenging ability of essential oil of from China.

Nat Prod Res 2020 Jul 14:1-5. Epub 2020 Jul 14.

School of Food Science, Shanxi Normal University, Linfen, China.

Chemical composition, antioxidant, DNA damage protective, nitrite scavenging activities, as well as antibacterial activity of Amomum kravanh fruits essential oil against several foodborne pathogens, were investigated. Results showed that the 1,8-cineole (58.53%) was found as the main component, followed by α-pinene (8. Read More

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Acute reductions in haematocrit increase flow-mediated dilatation independent of resting nitric oxide bioavailability in humans.

J Physiol 2020 10 29;598(19):4225-4236. Epub 2020 Jul 29.

Centre for Heart, Lung, & Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan, Kelowna, BC, Canada.

Key Points: Changes in haematocrit influence nitric oxide signalling through alterations in shear stress stimuli and haemoglobin scavenging of nitric oxide; these two regulatory factors have not been assessed simultaneously Isovolumic haemodilution led to a marked increase in brachial artery flow-mediated dilatation in humans The increase in flow-mediated dilatation occurred in the face of an unaltered shear stress stimulus for vasodilatation and reduced resting steady-state nitric oxide levels in the blood Collectively, our data point towards haemoglobin scavenging of nitric oxide as a key regulatory factor of brachial flow-mediated dilatation and highlight the importance of the simultaneous consideration of nitric oxide production and inactivation when investigating vascular function in humans ABSTRACT: Haemoglobin (Hb) may impact the transduction of endothelium-dependent and nitric oxide (NO)-mediated vasodilator activity, given its contribution to shear stress stimuli and diverse biochemical reactions with NO. We hypothesized that an acute reduction in [Hb] and haematocrit (Hct) would increase brachial artery flow-mediated dilatation (FMD). In 11 healthy males (28 ± 7 years; 23 ± 2 kg m ), FMD (Duplex ultrasound), arterial blood gases, Hct and [Hb], blood viscosity, and NO metabolites (ozone-based chemiluminescence) were measured before and after isovolumic haemodilution, where ∼20% of whole blood was removed and replaced with 5% human serum albumin. Read More

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October 2020

Antioxidant and Anti-Inflammatory Activities of Ledeb. Extract.

Evid Based Complement Alternat Med 2020 15;2020:8571207. Epub 2020 Jun 15.

Department of Food and Nutrition, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.

The purpose of this study is to investigate the effect of Ledeb. extract (APLE) on lipopolysaccharide- (LPS-) induced cell damage in hepatocytes with a focus on antioxidant and anti-inflammatory activities. Total antioxidant and anti-inflammatory activities of APLE itself were analyzed and phytochemical analysis was performed. Read More

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Isolation of bioactive compounds from Rumex hastatus extract and their biological evaluation and docking study as potential anti-oxidant and anti-urease agents.

J Food Biochem 2020 08 16;44(8):e13320. Epub 2020 Jun 16.

School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian, China.

Herein, the methanolic extract of Rumex hastatus was prepared and subjected to silica gel column chromatographic separation for purification. The chromatographic analysis yielded four bioactive compounds namely, 1,8-dihydroxy-3-methyl-anthraquinone (C1, chrysophanol), 3-methoxy-7-methyl-1,5-dihydroxy-anthraquinone (C2), 6-methyl-1,3,7-trihydroxy-anthraquinone (C3), and 4-hydroxycinnamic acid (C4). The structures of all the isolated bio-entities were elucidated by spectroscopic analysis (1D, 2D-NMR, and MS). Read More

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Roles for Plant Mitochondrial Alternative Oxidase Under Normoxia, Hypoxia, and Reoxygenation Conditions.

Front Plant Sci 2020 15;11:566. Epub 2020 May 15.

Department of Biology, Memorial University of Newfoundland, St. John's, NL, Canada.

Alternative oxidase (AOX) is a non-energy conserving terminal oxidase in the plant mitochondrial electron transport chain (ETC) that has a lower affinity for oxygen than does cytochrome (cyt) oxidase. To investigate the role(s) of AOX under different oxygen conditions, wild-type (WT) plants were compared with AOX knockdown and overexpression plants under normoxia, hypoxia (near-anoxia), and during a reoxygenation period following hypoxia. Paradoxically, under all the conditions tested, the AOX amount across plant lines correlated positively with leaf energy status (ATP/ADP ratio). Read More

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Pharmacological potential of tocopherol and doxycycline against traumatic brain injury-induced cognitive/motor impairment in rats.

Brain Inj 2020 07 4;34(8):1039-1050. Epub 2020 Jun 4.

Department of Neuropharmacology, ISF College of Pharmacy , Moga, Punjab, India.

Primary Objective The primary objective of this study was to explore the pharmacological potential of tocopherol and doxycycline against traumatic brain injury-induced cognitive/motor impairment in rats. Research Design Weight drop model of traumatic brain injury. Methods and Procedures After TBI, the animals were treated with doxycycline (50 and 100 mg/kg; p. Read More

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Nitric Oxide Modulation by Folic Acid Fortification.

Antioxidants (Basel) 2020 May 7;9(5). Epub 2020 May 7.

Okinawa Industrial Technology Center, 12-2 Suzaki, Uruma, Okinawa 904-2234, Japan.

Folic acid (FA) can be protected the neural tube defects (NTDs) causing nitric oxide (NO) induction, but the alleviation mechanism of the detailed FA function against NO has not yet been clarified. This study focused on elucidation of the interaction of FA and NO. FA suppressed nitrite accumulation as the NO indicator in lipopolysaccharide (LPS)-stimulated RAW264. Read More

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Caesalpinia crista coat extract protects red blood cell from sodium nitrite-induced oxidative stress and exhibits antiplatelet activity.

Blood Coagul Fibrinolysis 2020 Jul;31(5):293-302

Department of Studies and Research in Biochemistry, Tumkur University, Tumakuru.

: To understand the RBC protecting efficiency and antiplatelet activity of methanolic extract of Caesalpinia crista coat (MECCC). RBC-protecting activity of MECCC was evaluated using assays, such as DPPH, level of lipid peroxidation, protein carbonyl content, superoxide dismutase and catalase as a marker of oxidative stress whereas, platelet aggregation inhibition was performed using human platelet-rich plasma (PRP). MECCC showed about 76% of DPPH-scavenging activity, with an IC50 value of 71. Read More

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Transcriptional and metabolic response against hydroxyethane-(1,1-bisphosphonic acid) on bacterial denitrification by a halophilic Pannonibacter sp. strain DN.

Chemosphere 2020 Aug 13;252:126478. Epub 2020 Mar 13.

Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Beijing, 100085, China.

Biological denitrification is an environmentally sound pathway for the elimination of nitrogen pollution in wastewater treatment. Extreme environmental conditions, such as the co-existence of toxic organic pollutants, can affect biological denitrification. However, the potential underlying mechanism remains largely unexplored. Read More

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Investigation of Chemical Composition, Antioxidant Activity, and the Effects of Alfalfa Flavonoids on Growth Performance.

Oxid Med Cell Longev 2020 10;2020:8569237. Epub 2020 Feb 10.

Jiangxi Province Key Laboratory of Animal Nutrition/Engineering Research Center of Feed Development, Jiangxi Agricultural University, Nanchang 330045, China.

The flavonoids were extracted from alfalfa using ethanol assisted with ultrasonic extraction and purified by D101 macroporous resin column chromatography. The chemical composition and content of ethanol elution fractions (EEFs) were assessed by ultrahigh-performance liquid chromatography and hybrid quadrupole time of flight mass spectrometry (UHPLC-Q-TOF-MS) and aluminum nitrate-sodium nitrite-sodium hydroxide colorimetric method. The antioxidant activity of two EEFs was conducted by scavenging DPPH free radical, and the main antioxidants of 75% EEFs were screened using DPPH-UHPLC. Read More

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September 2020

Chemical characterization of balloon flower () sprout extracts and their regulation of inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells.

Food Sci Nutr 2020 Jan 3;8(1):246-256. Epub 2019 Dec 3.

Division of Functional Food & Nutrition Department of Agrofood Resources National Institute of Agricultural Sciences Rural Development Administration Wanju Korea.

The balloon flower (BF) is a potent natural source of phytochemical compounds and is associated with our health. The sprouting process is accompanied by significant changes in phytochemical compounds in comparison with their original plants. Even though many studies are conducted with BF, there are not yet reports of BF sprouts. Read More

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January 2020

Synthesis, characterization and anti-inflammatory activity evaluation of 1,2,4-triazole and its derivatives as a potential scaffold for the synthesis of drugs against prostaglandin-endoperoxide synthase.

J Biomol Struct Dyn 2021 Feb 10;39(2):457-475. Epub 2020 Jan 10.

Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.

Substituted 1,2,4-triazole nucleus is common in several drugs used in a variety of clinical conditions including infections, hypoglycemia, hypertension and cancer. In this study, we synthesized 1,2,4-triazole and its 16 hydrazone derivatives (B1-B16), characterized them by IR, NMR and Mass spectroscopy, and evaluated their radical scavenging and anti-inflammatory activities and . Out of 16 derivatives, five (B1, B5, B6, B9, and B13) demonstrated a significant radical scavenging and anti-inflammatory activity . Read More

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February 2021