Pathogens 2021 May 31;10(6). Epub 2021 May 31.
American Type Culture Collection (ATCC®), ATCC Federal Solutions, 10801 University Boulevard, Manassas, VA 20110, USA.
Powassan virus (POWV) is a tick-borne flavivirus circulating in North America and the Russian Far East that can cause severe neuroinvasive diseases, including encephalitis, meningitis, and meningoencephalitis. The reported neuroinvasive case fatality is about 10%, and approximately 50% of the survivors from the neuroinfection exhibit long-lasting or permanent neurological sequelae. Currently, treatment of POWV infection is supportive, and no FDA-approved vaccines or specific therapeutics are available. Read More