Neurophysiol Clin 2021 Sep 1. Epub 2021 Sep 1.
INSERM U1105, Université de Picardie, GRAMFC, CURS, CHU Sud, rue René Laennec, 80036 Amiens Cedex 1, France; INSERM U1105, EFSN Pédiatrique, CHU Amiens sud, Avenue Laennec, 80054 Amiens cedex.
Objectives: Reversal learning is widely used to analyze cognitive flexibility and characterize behavioral abnormalities associated with impulsivity and disinhibition. Recent studies using fMRI have focused on regions involved in reversal learning with negative and positive reinforcers. Although the frontal cortex has been consistently implicated in reversal learning, few studies have focused on whether reward and punishment may have different effects on lateral frontal structures in these tasks. Read More