Kaibogaku Zasshi 2000 Jun;75(3):285-97
Department of Anatomy, Toho University School of Medicine, Tokyo, Japan.
Laminar distribution and synaptic organization of non-cholinergic projections to the medial limbic cortex from the basal forebrain (BF) were studied in rats. To eliminate BF cholinergic neurons selectively, a immunotoxin, 192IgG-saporin, was injected into lateral ventricle, and 7 days later, to label the remaining non-cholinergic elements, Phaseolus vulgaris-leucoagglutinin (PHA-L) was injected into BF. In rats injected with the toxin, PHA-L labeled fibers, presumably originating from the remaining non-cholinergic neurons, were distributed in layers V-VI of the medial limbic cortex. Read More