1,274,924 results match your criteria neurologic

Identifying patients at risk for nonroutine discharge after surgery for cervical myelopathy: an analysis from the Quality Outcomes Database.

J Neurosurg Spine 2021 May 7:1-9. Epub 2021 May 7.

15Department of Neurological Surgery, University of Utah, Salt Lake City, Utah.

Objective: Optimizing patient discharge after surgery has been shown to impact patient recovery and hospital/physician workflow and to reduce healthcare costs. In the current study, the authors sought to identify risk factors for nonroutine discharge after surgery for cervical myelopathy by using a national spine registry.

Methods: The Quality Outcomes Database cervical module was queried for patients who had undergone surgery for cervical myelopathy between 2016 and 2018. Read More

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Treatment and outcomes of Multidrug-resistant tuberculosis in Auckland 1995-2018.

Intern Med J 2021 May 7. Epub 2021 May 7.

Department of Infectious Disease, Auckland City Hospital, Auckland, New Zealand.

Introduction: New Zealand has a low burden of tuberculosis, however multidrug-resistant tuberculosis (MDR-TB) still represents a challenge for clinicians. This is the first description of clinical aspects of MDR-TB in New Zealand.

Methods: Clinical data were obtained for patients treated for MDR-TB at Auckland District Health Board (ADHB). Read More

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Effective Patient Selection for an Oncology-Dedicated Emergency Service: A Retrospective Study.

JCO Oncol Pract 2021 May 7:OP2001081. Epub 2021 May 7.

Cancer Center, Emek Medical Center, Afula, Israel.

Purpose: Emergency cancer care constitutes a significant health care and patient burden. The purpose of this study was to identify characteristics of patients most fitting for treatment in an oncology-dedicated emergency department (OED).

Methods: Electronic files of patients with cancer seeking emergency services between April and June 2017 were retrospectively obtained from the hospital registry. Read More

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[Diagnosis, Treatment and Complications of Knee Dislocation: a Retrospective Study].

Acta Chir Orthop Traumatol Cech 2021 ;88(2):107-116

Klinika ortopedie a traumatologie pohybového ústrojí a Lékařské fakulty Univerzity Karlovy a Fakultní nemocnice, Plzeň.

PURPOSE OF THE STUDY Acute knee dislocation is a less common injury of the knee joint. It is, however, a serious injury with a high rate of nerve and vascular damage and it is considered a limb threatening injury with long-term functional disability, which can ultimately lead to amputation. Knee dislocations constitute less than 0. Read More

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January 2021

Congenital defects of glycosylation: Novel presentations with mainly neurological involvement and variable dysmorphic features.

Am J Med Genet A 2021 May 7. Epub 2021 May 7.

Faculty of Medicine, Department of Metabolic Diseases, Gazi University, Ankara, Turkey.

The pathophysiology of congenital defects of glycosylation (CDG) is complex and the diagnosis has been a challenge because of the overlapping clinical signs and symptoms as well as a large number of disorders. Isoelectric focusing of transferrin has been used as a screening method but has limitations. Individual enzyme or molecular genetic tests have been difficult to perform. Read More

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Studies of aging nonhuman primates illuminate the etiology of early-stage Alzheimer's-like neuropathology: An evolutionary perspective.

Am J Primatol 2021 May 7:e23254. Epub 2021 May 7.

Division of Neuropharmacology and Neurologic Diseases, Department of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.

Tau pathology in Alzheimer's disease (AD) preferentially afflicts the limbic and recently enlarged association cortices, causing a progression of mnemonic and cognitive deficits. Although genetic mouse models have helped reveal mechanisms underlying the rare, autosomal-dominant forms of AD, the etiology of the more common, sporadic form of AD remains unknown, and is challenging to study in mice due to their limited association cortex and lifespan. It is also difficult to study in human brains, as early-stage tau phosphorylation can degrade postmortem. Read More

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Pathogenesis, diagnosis and treatment of paraneoplastic neurologic syndromes.

Franz Blaes

Expert Rev Neurother 2021 May 7. Epub 2021 May 7.

Department of Neurology, KKH Gummersbach, Wilhelm-Breckow-Allee 20, 51643 Gummersbach, Germany.

Introduction: Paraneoplastic neurological syndromes (PNS) are a rare heterogeneous group of neurological diseases associated with tumors. These syndromes are the result of a cross-reactive immune response against antigens shared by the tumor and the nervous system. The discovery of an increasing number of autoantigens and the identification of tumoral factors leading to a substantial antitumoral immune response makes this topic highly innovative. Read More

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Directing a dispersion cannula tip toward the aortic root during thoracic aortic arch surgery does not adversely affect cardiac function.

Perfusion 2021 May 7:2676591211014816. Epub 2021 May 7.

Department of Thoracic and Cardiovascular Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan.

Introduction: Neurologic complications of open thoracic aortic surgery are devastating problems in patients with severely diseased aortas. This study aimed to clarify whether directing the aortic cannula tip toward the aortic root affects the postoperative cardiac function in patients undergoing open thoracic aortic surgery.

Methods: A total of 16 patients who underwent total or partial arch replacement between January 2014 and April 2019 were enrolled and divided into two groups. Read More

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Rapid Neurocognitive Deterioration and Mortality in a Healthcare Professional With Spongiform Encephalopathy: Implications for Neurologic and End-of-Life Care.

Cureus 2021 Apr 3;13(4):e14277. Epub 2021 Apr 3.

Neurology, College of Osteopathic Medicine, Kansas City University, Kansas City, USA.

Spongiform encephalopathy (SE) is a rare prion disorder characterized by progressive cognitive dysfunction and mortality. Affected patients can observe a wide variety of neurological symptoms, such as myoclonus, dementia, cerebellar signs, and others. We present a case of laboratory-confirmed SE in an otherwise healthy 57-year-old medical professional who initially presented with nonspecific and unique "head in a fish-bowl" dissociation and cognitive decline. Read More

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Tectorial Membrane Injury, Frequently Identified in Adult Trauma Patients Who Undergo Occipital-Cervical Fusion for Craniocervical Instability.

Cureus 2021 Apr 2;13(4):e14254. Epub 2021 Apr 2.

Neuroradiology, University of Florida College of Medicine, Jacksonville, USA.

Background In the absence of frank craniocervical dissociation, there is a lack of consensus regarding what patterns of craniocervical junction ligamentous injuries require occipital-cervical fusion. This study was undertaken to examine the integrity of the craniocervical junction ligaments and analyze clinical outcomes in patients who underwent occipital-cervical fusion for craniocervical junction injury. Methods Adult patients requiring occipital-cervical fusion were identified retrospectively utilizing keyword searches in cervical computed tomography and magnetic resonance imaging reports between 2012 and 2020 using Nuance mPower software (Nuance, Burlington, MA). Read More

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Characteristics of Tc-MEP Waveforms in Spine Surgery for Patients with Severe Obesity.

Spine (Phila Pa 1976) 2021 May 6. Epub 2021 May 6.

Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan Department of Orthopedic Surgery, Kansai Medical University, Osaka, Japan Department of Orthopedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan Department of Orthopedic Surgery, Kurume University School of Medicine, Kurume, Japan Department of Orthopedic Surgery, Yamaguchi Rosai Hospital, Yamaguchi, Japan Department of Orthopedic Surgery, Hiroshima City Asa Citizens Hospital, Hiroshima, Japan Department of Orthopedic Surgery, Wakayama Medical University, Wakayama, Japan Department of Orthopedic Surgery, Nara Medical University, Nara, Japan Department of Orthopedic Surgery, Kochi University, Kochi, Japan Department of Orthopedic Surgery, Kyorin University, Tokyo, Japan Department of Orthopedic Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan Department of Orthopedic Surgery, Tokyo Women's Medical University Medical Center East, Tokyo, Japan Department of Orthopedic Surgery, Yamaguchi University, Yamaguchi, Japan Department of Orthopedic Surgery, National Defense Medical College Hospital, Saitama, Japan Division of Central Clinical Laboratory, Nara Medical University, Nara, Japan Department of Orthopedic Surgery, Kubokawa Hospital, Kochi, Japan.

Study Design: Prospective multicenter study.

Objective: To evaluate transcranial motor evoked potential (Tc-MEP) waveform monitoring in spinal surgery for patients with severe obesity.

Summary Of Background Data: Spine surgeries in obese patients are associated with increased morbidity and mortality. Read More

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ACR Appropriateness Criteria® Syncope.

J Am Coll Radiol 2021 May;18(5S):S229-S238

Specialty Chair, UT Southwestern Medical Center, Dallas, Texas, Chief, Cardiothoracic Imaging, UT Southwestern, Member BOD, SCCT, Editor, Radiology - Cardiothoracic Imaging.

Syncope and presyncope lead to well over one million emergency room visits in the United States each year. Elucidating the cause of syncope or presyncope, which are grouped together given similar etiologies and outcomes, can be exceedingly difficult given the diverse etiologies. This becomes more challenging as some causes, such as vasovagal syncope, are relatively innocuous while others, such as cardiac-related syncope, carry a significant increased risk of death. Read More

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ACR Appropriateness Criteria® Head Trauma: 2021 Update.

J Am Coll Radiol 2021 May;18(5S):S13-S36

Specialty Chair, Atlanta VA Health Care System and Emory University, Atlanta, Georgia.

Head trauma (ie, head injury) is a significant public health concern and is a leading cause of morbidity and mortality in children and young adults. Neuroimaging plays an important role in the management of head and brain injury, which can be separated into acute (0-7 days), subacute (<3 months), then chronic (>3 months) phases. Over 75% of acute head trauma is classified as mild, of which over 75% have a normal Glasgow Coma Scale score of 15, therefore clinical practice guidelines universally recommend selective CT scanning in this patient population, which is often based on clinical decision rules. Read More

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Clinical, Immunological, and Genetic Features in 938 Patients with Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED): a Systematic Review.

Expert Rev Clin Immunol 2021 May 6. Epub 2021 May 6.

Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare inborn immune error associated with the autoimmune regulator () gene mutation. It is classically characterized by a triad of chronic mucocutaneous candidiasis (CMC), hypoparathyroidism (HP), and adrenal insufficiency (ADI).

Methods: Literature search was conducted in PubMed, Web of Science, and Scopus databases using related keywords, and included studies were systematically evaluated. Read More

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Sustained Dysbiosis and Decreased Fecal Short Chain Fatty Acids after Traumatic Brain Injury and Impact on Neurologic Outcome.

J Neurotrauma 2021 May 6. Epub 2021 May 6.

University of Pittsburgh School of Medicine, 12317, Critical Care Medicine, Pittsburgh, Pennsylvania, United States;

Traumatic brain injury (TBI) alters microbial populations present in the gut, which may impact healing and tissue recovery. However, the duration and impact of these changes on outcome from TBI are unknown. Short chain fatty acids (SCFAs), produced by bacterial fermentation of dietary fiber, are important signaling molecules in the microbiota-gut-brain axis. Read More

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Coil assisted glue embolization to improve safety and accuracy in endovascular management of Vein of Galen patients.

Clin Neurol Neurosurg 2021 Apr 21;205:106652. Epub 2021 Apr 21.

Army Hospital (Referral & Research), Delhi Cantt, New Delhi 110010, India. Electronic address:

Background: Vein of Galen malformation (VOGM) patients present in neonatal age with cardiac failure or significant neurologic consequences. The most established method of treatment has been transarterial embolization with high concentration glue (N-Butyl Cyano Acrylate) which may be difficult to control due to very high flow rates and may migrate to the venous side with undesirable consequences. We describe our experience in four patients in whom initial coil placement in prominent feeding arteries helped inflow reduction thereby facilitating controlled glue injection with a good result and no incidence of non-target embolization. Read More

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Multidisciplinary management of a traumatic posterior meningeal artery pseudoaneurysm: A case report and review of the literature.

Int J Surg Case Rep 2021 Apr 29;82:105933. Epub 2021 Apr 29.

Department of Surgery, Division of Trauma and Surgical Critical Care, Kendall Regional Medical Center, Miami, FL, USA; University of South Florida, Tampa, FL, USA.

Background: Meningeal arterial injuries represent <1% of all blunt traumatic brain injuries (TBIs). Middle meningeal artery (MMA) lesions comprise the majority. However, there is little clinical data on posterior meningeal artery (PMA) injuries. Read More

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Hyperbaric oxygen therapy in the treatment of pneumocephalus associated with epidural block - case report.

Braz J Anesthesiol 2021 May 3. Epub 2021 May 3.

Unidade Local de Saúde de Matosinhos (ULSM), Anesthesia Department, Portugal; Unidade Local de Saúde de Matosinhos (ULSM), Hyperbaric Medicine Unit, Portugal.

Introduction: Pneumocephalus is a rare neuraxial blockade complication, which can be associated with severe neurologic changes.

Clinical Case: A 51-year-old patient was submitted to left total knee arthroplasty. Postoperatively, a pneumocephalus associated with decreased consciousness was diagnosed as a complication of the epidural analgesia. Read More

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Anxiety-Related Adverse Event Clusters After Janssen COVID-19 Vaccination - Five U.S. Mass Vaccination Sites, April 2021.

MMWR Morb Mortal Wkly Rep 2021 May 7;70(18):685-688. Epub 2021 May 7.

CDC COVID-19 Response Team.

On April 7, 2021, after 5 weeks' use of the Janssen COVID-19 vaccine under the Food and Drug Administration (FDA) Emergency Use Authorization (EUA), CDC received reports of clusters of anxiety-related events after administration of Janssen COVID-19 vaccine from five mass vaccination sites, all in different states. To further investigate these cases, CDC interviewed vaccination site staff members to gather additional information about the reported events and vaccination site practices. Four of the five sites temporarily closed while an investigation took place. Read More

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Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.

MMWR Recomm Rep 2021 05 7;70(2):1-30. Epub 2021 May 7.

Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC.

Botulism is a rare, neurotoxin-mediated, life-threatening disease characterized by flaccid descending paralysis that begins with cranial nerve palsies and might progress to extremity weakness and respiratory failure. Botulinum neurotoxin, which inhibits acetylcholine release at the neuromuscular junction, is produced by the anaerobic, gram-positive bacterium Clostridium botulinum and, rarely, by related species (C. baratii and C. Read More

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Transarterial embolization with n-butyl cyanoacrylate for the treatment of active abdominopelvic bleeding in the polytraumatized patient.

CVIR Endovasc 2021 May 6;4(1):39. Epub 2021 May 6.

Division of Interventional Radiology, Department of Radiology, Hematology and Oncology, Medical School of Ribeirão Preto, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, SP, 14048-090, Brazil.

Purpose: An increasing number of polytraumatized patient presenting with active abdominal pelvic bleeding (APB) have been treated by endovascular selective embolization. However, reports on evaluate the efficacy, safety and complications caused by this technique have been limited. The aim of this study was to assess the safety and efficacy of embolization of APB using N-butyl cyanoacrylate glue (NBCA). Read More

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A First Report on Experience in Managing Infants with Congenital Toxoplasmosis in Ethiopia: Case Reports and a Review of Evaluation and Treatment.

Case Rep Infect Dis 2021 15;2021:9934391. Epub 2021 Apr 15.

Division of Neonatology, Department of Pediatrics and Child Health, Addis Ababa University, Addis Ababa, Ethiopia.

. Congenital toxoplasmosis is a major sequela of untreated primary maternal infection. With or without symptoms, untreated infections eventually lead to multiple neurologic complications. Read More

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The potential neuroprotective roles of olive leaf extract in an epilepsy rat model induced by kainic acid.

Res Pharm Sci 2021 Feb 30;16(1):48-57. Epub 2020 Dec 30.

Department of Physiology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran.

Background And Purpose: Epilepsy is recognized as a chronic neurologic disease. Increasing evidence has addressed the antioxidant and anti-inflammatory roles of olive leaf extract (OLE) in neurodegenerative diseases. So, the current study aimed to investigate the neuroprotective roles of OLE in epilepsy. Read More

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February 2021

Improving "Neuro Checks" in Neonatal ICU and PICU Is a Serial Neurologic Assessment in Pediatrics.

Kerri L LaRovere

Pediatr Crit Care Med 2021 May;22(5):512-514

Department of Neurology, Boston Children's Hospital, Boston, MA.

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Early Risk of Readmission Following Hospitalization for Reversible Cerebral Vasoconstriction Syndrome.

Neurology 2021 May 5. Epub 2021 May 5.

Department of Neurology, Neurosurgery, and Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA

Objective: For evaluation of 90-day readmissions following an inpatient admission for reversible cerebral vasoconstriction syndrome (RCVS), hospitalizations due to RCVS were identified from the Nationwide Readmissions Database 2016-2017.

Methods: The primary outcome of interest was non-elective readmission within 90 days of index hospitalization discharge. Survival analysis was performed, and multivariable Cox proportional hazards regression was used to determine the factors associated with readmission. Read More

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Intracerebral Hemorrhage: A Common yet Disproportionately Deadly Stroke Subtype.

Mayo Clin Proc 2021 May 2. Epub 2021 May 2.

Departments of Critical Care Medicine, Neurologic Surgery, and Neurology, Mayo Clinic, Jacksonville, FL.

Spontaneous intracerebral hemorrhage (ICH) is a medical emergency and is disproportionately associated with higher mortality and long-term disability compared with ischemic stroke. The phrase "time is brain" was derived for patients with large vessel occlusion ischemic stroke in which approximately 1.9 million neurons are lost every minute. Read More

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