12,888 results match your criteria nephrolithiasis diagnosed


Stones left unturned: Missed opportunities to diagnose primary hyperparathyroidism in patients with nephrolithiasis.

Surgery 2021 Jul 27. Epub 2021 Jul 27.

Department of Surgery, Section of Endocrine Surgery, Yale School of Medicine, New Haven, CT. Electronic address:

Background: Nephrolithiasis is a sequela of primary hyperparathyroidism and an indication for parathyroidectomy. The prevalence of primary hyperparathyroidism in patients with nephrolithiasis is 3% to 5%; however, recent studies suggest that many hypercalcemic patients with nephrolithiasis never undergo workup for primary hyperparathyroidism. Our goal is to evaluate primary hyperparathyroidism screening rates at a tertiary academic health institution and identify opportunities to increase referral rates in patients presenting with nephrolithiasis. Read More

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Prevalence of Renal Stones Among Patients With Inflammatory Bowel Disease in Saudi Arabia.

Cureus 2021 Jun 21;13(6):e15787. Epub 2021 Jun 21.

Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.

Introduction: Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) that affect the gastrointestinal tract with no identified etiology. IBD has been associated with several extraintestinal manifestations (EIMs), including renal involvement such as renal stones (nephrolithiasis), resulting in significant morbidity. This study aims to estimate the prevalence of renal stones among IBD patients in Saudi Arabia. Read More

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The new patterns of nephrolithiasis: What has been changing in the last millennium?

Arch Ital Urol Androl 2021 Jun 28;93(2):195-199. Epub 2021 Jun 28.

Unità Complessa di Urologia, Dipartimento di Chirurgia Specialistica, Ospedale Ca' Foncello, Treviso.

Nephrolithiasis has been increasing over the last millennium. Although early epidemiologic studies have shown that kidney stones were two to three times more frequent in males than in females, recent reports have suggested that this rate is decreasing. In parallel a dramatic increase of nephrolithiasis has also been observed among children and adolescents. Read More

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A Rare Genetic Mutation in a Stone Former.

Indian J Nephrol 2021 Mar-Apr;31(2):197-200. Epub 2021 Apr 2.

Department of Nephrology, Government Stanley Medical College, Chennai, Tamil Nadu, India.

A 30-year-old woman with history of passage of stones since childhood presented with oliguria and pedal edema for 10 days. She had hypertension with a creatinine of 4.1 mg/dL. Read More

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Laparoscopic ureterolithotomy and retrograde flexible ureteroscopy-assisted transperitoneal laparoscopic ureteroureterostomy for a huge ureteropelvic junction stone and multiple small renal stones: A CARE-compliant case report.

Medicine (Baltimore) 2021 Jul;100(28):e26655

Department of Urology, China Medical University Hospital, Taichung, Taiwan.

Rationale: Concurrent kidney and ureteral stones are always complicated and a clinical challenge. Improvements in endoscopic equipment have led to the widespread adoption of retrograde intrarenal surgery, which has a good stone clearance rate. On the other hand, laparoscopic ureterolithotomy (LUL) has been reported to be non-inferior to retrograde flexible ureteroscopy in stone-free rate and the need for axillary procedures, and to have a significantly lower rate of post-operative sepsis compared to retrograde flexible ureteroscopy. Read More

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Primary hyperoxaluria diagnosed after kidney transplant: A review of the literature and case report of aggressive renal replacement therapy and lumasiran to prevent allograft loss.

Am J Transplant 2021 Jul 13. Epub 2021 Jul 13.

Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Primary hyperoxaluria type 1 is a rare inherited disorder caused by abnormal liver glyoxalate metabolism leading to overproduction of oxalate, progressive kidney disease, and systemic oxalosis. While the disorder typically presents with nephrocalcinosis, recurrent nephrolithiasis, and/or early chronic kidney disease, the diagnosis is occasionally missed until it recurs after kidney transplant. Allograft outcomes in these cases are typically very poor, often with early graft loss. Read More

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Urologiia 2021 Jun(3):87-91

Privolzhskiy Research Medical University, Nizhny Novgorod, Russia.

Objective: To discuss the feasibility, safety, and effectiveness of conventional laparoscopic partial nephrectomy combined with pyelolithotomy for patients with ipsilateral renal tumor and staghorn kidney stone.

Materials And Methods: Retrospective multicentral comparative study. Group "Combo" was presented by patients with the mentioned combined pathology (n=15). Read More

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[Characteristics of pathogenesis and manifestations of nephrolithiasis in patients with chronic cardiovascular diseases].

Urologiia 2021 Jun(3):33-38

N.A. Lopatkin Research Institute of Urology and Interventional Radiology branch of the National Medical Research Radiological Center, Moscow, Russia.

Aim: To study the pathogenetic and clinical features of nephrolithiasis in patients with concomitant chronic cardiovascular diseases (CVD), particularly the chemical composition of renal stones, the frequency of relapses, as well as the daily dynamics of the urine specific gravity and acidity level as the main factors of stone formation.

Materials And Methods: A total of 270 patients were treated in the Department of the urology No. 1 of the "Main Military Clinical Hospital named after N. Read More

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Is Retrograde Intrarenal Surgery as Safe for Children as It Is for Adults?

Urol Int 2021 Jul 9:1-7. Epub 2021 Jul 9.

Department of Urology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.

Introduction: The primary aim of this study is to compare the efficacy and safety of retrograde intrarenal surgery (RIRS) among the children and adults with similar stone burdens and locations. Also, the secondary aim of this study is to identify the factors affecting the stone-free rates (SFRs) of RIRS.

Methods: We retrospectively compared perioperative results, SFRs, and complication rates (CRs) between pediatric (group 1, n: 55) and adult (group 2, n: 220) age groups diagnosed with kidney stones and treated by flexible ureterorenoscopy using the same instruments. Read More

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Serious diagnoses at revisits in children discharged from the emergency department with back pain.

Acad Emerg Med 2021 Jul 10. Epub 2021 Jul 10.

Division of Emergency Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Background: Back pain is often benign but can be a harbinger for serious pathology. Little is known about the outcome in children with back pain but no serious diagnoses detected at the initial visit. We sought to estimate the rate of serious diagnoses at revisits among children initially discharged from the emergency department (ED) with back pain. Read More

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Racial disparities in the utilization of parathyroidectomy among patients with primary hyperparathyroidism: Evidence from a nationwide analysis of Medicare claims.

Surgery 2021 Jul 3. Epub 2021 Jul 3.

Department of Surgery, Stanford University School of Medicine, Palo Alto, CA; Stanford-Surgery Policy Improvement Research and Education Center (S-SPIRE), Department of Surgery, Stanford University School of Medicine, Palo Alto, CA; Division of General Surgery, Palo Alto Veterans Affairs Health Care System, Palo Alto, CA. Electronic address:

Background: Among patients with primary hyperparathyroidism, parathyroidectomy offers a chance of cure and mitigation of disease-related complications. The impact of race/ethnicity on referral and utilization of parathyroidectomy has not been fully explored.

Methods: Population-based, retrospective cohort study using 100% Medicare claims from beneficiaries with primary hyperparathyroidism from 2006 to 2016. Read More

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Study of Association of Metabolic Syndrome and Risk Factors of Nephrolithiasis.

J Assoc Physicians India 2021 Jan;69(1):32-35

Senior Resident, Dept. of Medicine, BRD Medical College, Gorakhpur, Uttar Pradesh.

Background And Aim: The increasing incidence of nephrolithiasis in recent decades is coinciding with rising epidemic of obesity, metabolic syndrome, and type 2 diabetes. This temporal concordance suggests that a link might exist between these metabolic abnormalities and urinary stone disease. Therefore, the present study was aimed to investigate the association between presence of risk factors of nephrolithiasis and metabolic syndrome. Read More

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January 2021

Primary Hyperparathyroidism in Pregnancy: Literature Review of the Diagnosis and Management.

J Clin Med 2021 Jun 30;10(13). Epub 2021 Jun 30.

Division of Endocrinology and Metabolism, McMaster University, Hamilton, ON L8S 4L8, Canada.

Background: Parathyroid disease is uncommon in pregnancy. During pregnancy, multiple changes occur in the calcium regulating hormones which may make the diagnosis of primary hyperparathyroidism more challenging. Close monitoring of serum calcium during pregnancy is necessary in order to optimize maternal and fetal outcomes. Read More

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Lipoma or Liposarcoma? Robotic Resection of a retroperitoneal mass.

J Obstet Gynaecol Can 2021 Jun 28. Epub 2021 Jun 28.

Division of Gynecology Oncology, Department of Obstetrics and Gynecology, Inova Fairfax Women's Hospital, 3300 Gallows Rd. 22042, Falls Church, VA, USA.

This video demonstrates a robotic excision of a large retroperitoneal lipomatous mass in a 48-year-old female with a known fibroid uterus. Computed tomography was performed for nephrolithiasis, and an incidental 7-cm fatty prominence in the right hemipelvis was found. Retroperitoneal tumours like benign lipomas and low-grade liposarcoma are difficult to differentiate. Read More

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Initial Experience with the New Super Thin Single-use Pusen Flexible Ureteroscope 7.5 Fr in Renal Stones Endoscopic Treatment.

Chirurgia (Bucur) 2021 May-Jun;116(3):354-360

Single-use flexible ureteroscopes (SU-fURS) seems to overcome the main limitations of conventional reusable ureteroscopes in terms of acquisition and maintenance costs and breakages. Our aim was to analyz the efficiency and safety of the thinnest single use flexible scope from Pusen: Uscope Pusen, PU 3033A (Tip = 7.5 Fr. Read More

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Primary Mucinous Adenocarcinoma of the Urinary Bladder: A Rare Entity.

West Afr J Med 2021 Jun;38(6):604-606

Clinipath Pathology (M) Sdn Bhd, Klang, Malaysia.

Adenocarcinoma constitutes around 0.5 to 2% of all neoplastic lesions of the urinary bladder, out of which, the mucinous variant is seen on rare occasions. Intestinal metaplasia resulting from nephrolithiasis, chronic inflammation and hydronephrosis could be the precursor lesion. Read More

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Identification of p.Arg205Cys in CASR in an autosomal dominant hypocalcaemia type 1 pedigree: A case report.

Medicine (Baltimore) 2021 Jun;100(25):e26443

Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.

Rationale: Autosomal dominant hypocalcaemia type 1 (ADH1) is a genetic disease characterized by benign hypocalcemia, inappropriately low parathyroid hormone levels and mostly hypercalciuria. It is caused by the activating mutations of the calcium-sensing receptor gene (CASR), which produces a left-shift in the set point for extracellular calcium.

Patient Concerns: A 50-year-old man presenting with muscle spasms was admitted into the hospital. Read More

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Does ureteral access sheath affect the outcomes of retrograde intrarenal surgery: a prospective study.

Minim Invasive Ther Allied Technol 2021 Jun 21:1-5. Epub 2021 Jun 21.

Department of Urology, Ankara Kecioren Training and Research Hospital, Ministry of Health - University of Health Sciences Turkey, Ankara, Turkey.

Objectives: To evaluate whether or not using a ureteral access sheath (UAS) affects the perioperative outcomes after retrograde intrarenal surgery (RIRS) performed in patients with renal stones.

Material And Methods: An observational study was carried out using data of 60 patients who underwent RIRS with the diagnosis of renal stones <2 cm between February 2017 and November 2017 at our institution. The data of the 60 patients were registered prospectively during the study period. Read More

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Primary Hyperparathyroidism Masquerading as Acute Pancreatitis.

Horm Metab Res 2021 Jun 21;53(6):377-381. Epub 2021 Jun 21.

Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana, Punjab, India.

Acute pancreatitis as an initial manifestation of primary hyperparathyroidism (PHPT) is a rare occurrence and timely diagnosis of PHPT is crucial in preventing repeat attack of pancreatitis. The study aimed at evaluating the clinico-radiological profile of patients admitted with acute pancreatitis as the index presentation of PHPT and to determine the factors associated with development of severe pancreatitis. This series included retrospective analysis of medical records of 30 patients admitted with acute pancreatitis as initial manifestation of PHPT. Read More

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Mild Idiopathic Infantile Hypercalcemia - Part 2: A Longitudinal Observational Study.

J Clin Endocrinol Metab 2021 Jun 17. Epub 2021 Jun 17.

Department of Pediatrics, Division of Endocrinology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Context: Idiopathic Infantile Hypercalcemia (IIH) is an uncommon disorder with variable clinical features. The natural history and response to dietary calcium and vitamin D restriction in IIH remains unclear.

Objective: The aim of this study is to describe the clinical and biochemical response to dietary calcium and vitamin D restriction in a genetically characterized cohort of mild IIH. Read More

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Outcomes Of Percutaneous Nephrolithotomy In Elder Age Patients-Single Center Experience.

J Ayub Med Coll Abbottabad 2021 Apr-Jun;33(2):217-221

Department of Urology and Kidney Transplant, Shifa International Hospital Islamabad, Pakistan.

Background: Urolithiasis is a prevailing ailment affecting all age groups across global population. In modern innovative industry endoscopic instruments alterations and miniaturization has simplified the interventional strategy for undertaking these procedures for renal stones. However, there has been paucity of studies regarding outcomes of Percutaneous Nephrolithotomy (PCNL) in elder age group. Read More

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Association of parathyroidectomy with 5-year clinically significant kidney stone events in patients with primary hyperparathyroidism.

Endocr Pract 2021 Jun 11. Epub 2021 Jun 11.

Department of Surgery, Stanford University School of Medicine, Palo Alto, CA.

Objective: Patients with primary hyperparathyroidism (PHPT) are at increased risk of kidney stones. Guidelines recommend parathyroidectomy in PHPT patients with a history of stone disease. This study aimed to compare the 5-year incidence of clinically significant kidney stone events in patients with PHPT treated with parathyroidectomy vs. Read More

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Mild Idiopathic Infantile Hypercalcemia - Part 1: Biochemical and Genetic Findings.

J Clin Endocrinol Metab 2021 Jun 14. Epub 2021 Jun 14.

Division of Endocrinology and Diabetes and Center for Bone Health, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States.

Context: Idiopathic Infantile Hypercalcemia (IIH), an uncommon disorder characterized by elevated serum concentrations of 1,25(OH)2D and low PTH levels, may present with mild to severe hypercalcemia during the first months of life. Biallelic variants in the CYP24A1 or SLC34A1 genes are associated with severe IIH. Little is known about milder forms. Read More

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Analysis of clinical factors associated with intraoperative and postoperative complications of retrograde intrarenal surgery.

J Pak Med Assoc 2021 Jun;71(6):1666-1670

Department of Urology, Ankara City Hospital, Ankara, Turkey.

The aim of this study was to evaluate the factors affecting intraoperative and postoperative complications in retrograde intrarenal surgery. In this retrospective cohort study, 706 retrograde intrarenal surgery procedures administered to 617 patients were reviewed. Intraoperative and postoperative complications were classified according to the modified Satava and modified Clavien classification systems. Read More

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[Necrotizing Fasciitis of the Right Thigh Caused by Emphysematous Pyelonephritis Due to a Staghorn Stone : A Case Report].

Hinyokika Kiyo 2021 Apr;67(4):147-152

The Department of Urology, Muroran City General Hospital.

We report a rare case of necrotizing fasciitis in the thigh induced by emphysematous pyelonephritis due to a staghorn stone. A 60-year-old female was diagnosed with a staghorn stone in the right kidney at another clinic. We referred her to another hospital for indication of percutaneous nephrolithotripsy. Read More

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[Efficacy and Safety of Retrograde Ureterorenoscopic Lithotripsy for Patients with Renal or Ureteral Anatomic Abnormalities or Urinary Diversion].

Hinyokika Kiyo 2021 Apr;67(4):133-139

The Department of Urology, Ijinkai Takeda General Hospital.

Retrograde ureterorenoscopic lithotripsy is one of the first-line therapies for urolithiasis. In some cases, however, thisapproach may be difficult to adopt because of factorss uch asrenal/ureteral anatomic abnormalities or urinary diversion. This study aims to investigate the safety and efficacy of retrograde ureterorenoscopic lithotripsy in patients with the above-mentioned conditions. Read More

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Normocalcemic Primary Hyperparathyroidism: Need for a Standardized Clinical Approach.

Endocrinol Metab (Seoul) 2021 Jun 1;36(3):525-535. Epub 2021 Jun 1.

Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, USA.

Since normocalcemic primary hyperparathyroidism (NHPT) was first defined at the Third International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism in 2008, many papers have been published describing its prevalence and possible complications. Guidelines for the management of this condition are still lacking, and making the diagnosis requires fulfillment of strict criteria. Recent studies have shown that intermittent oscillations of serum calcium just below and slightly above the normal limits are very frequent, therefore challenging the assumption that serum calcium must be consistently normal to make the diagnosis. Read More

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Results of a Gene Panel Approach in a Cohort of Patients with Incomplete Distal Renal Tubular Acidosis and Nephrolithiasis.

Kidney Blood Press Res 2021 Jun 9:1-6. Epub 2021 Jun 9.

U.O.S. Terapia Conservativa della Malattia Renale Cronica, U.O.C. Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Background: Distal renal tubular acidosis (dRTA) is characterized by an impairment of urinary acidification resulting in metabolic acidosis, hypokalemia, and inappropriately elevated urine pH. If not treated, this chronic condition eventually leads to nephrocalcinosis, nephrolithiasis, impaired renal function, and bone demineralization. dRTA is a well-defined entity that can be diagnosed by genetic testing of 5 genes known to be disease-causative. Read More

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The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature.

Case Rep Endocrinol 2021 20;2021:5551203. Epub 2021 May 20.

Milton Keynes University Hospital, Standing Way, Eaglestone, Milton Keynes MK6 5LD, UK.

Hypercalcaemia and its systemic sequelae are a relatively common finding amongst patients in the field of endocrinology. Primary hyperparathyroidism, a frequent cause of hypercalcaemia, is often seen among middle-aged female patients, typically resulting from an underlying single-gland adenoma. Although patients may present with symptoms (nephrolithiasis, musculoskeletal discomfort, dehydration, or mood disturbance, to name a few), hypercalcaemia is rather frequently identified incidentally. Read More

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Safety and Efficacy of Flexible Ureterorenoscopy Surgery in Different Age Groups.

J Coll Physicians Surg Pak 2021 Jun;30(6):679-685

Department of Urology, HSU Ankara Diskapi Training and Research Hospital, Ankara, Turkey.

Objective: To comparatively investigate the efficacy, safety and complications of flexible ureterorenoscopy (f-URS) in the treatment of patients of different age groups (<60, 60-74 and ≥75 years) with proximal ureteral and kidney stones.

Study Design: Descriptive study.

Place And Duration Of Study: Department of Urology, HSU Izmir Bozyaka Training and Research Hospital, HSU Ankara Diskapi Training, Research Hospital, and Mustafa Kemal University Faculty of Medicine, between March 2014 and June 2020. Read More

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