8,512 results match your criteria nephrectomy partial

Health-related quality of life in patients with small renal mass who underwent robot-assisted partial nephrectomy: A prospective evaluation.

J Endourol 2021 May 11. Epub 2021 May 11.

Hamamatsu University School of Medicine, Urology, Hamamatsu, Shizuoka, Japan;

Introduction: There have been insufficient data regarding the impact of partial nephrectomy (PN) with minimal invasive approaches, including robot-assisted PN (RAPN), on postoperative quality of life (QOL) in patients with small renal mass (SRM). The objective of this study was to investigate the changes in health-related quality of life (HR-QOL) outcomes in patients with SRM who underwent RAPN.

Methods:  We performed a prospective observational study including 100 consecutive patients with SRM who underwent RAPN at our institution between April 2016 and August 2018. Read More

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Renal artery embolization in the treatment of urinary fistula after renal duplication: A case report and review of literature.

World J Clin Cases 2021 May;9(13):3177-3184

Department of Interventional Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210029, Jiangsu Province, China.

Background: Duplicate renal malformation is a congenital disease of the urinary system, with an incidence rate of 0.8%. Surgical treatment is suitable for symptomatic patients. Read More

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Renal Cell Carcinoma in Fistulizing Crohn's Disease Patient Who Received Anti-TNF Therapy.

Case Rep Gastrointest Med 2021 21;2021:5593067. Epub 2021 Apr 21.

Radiology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia.

Inflammatory bowel diseases are chronic inflammatory diseases affecting the gastrointestinal tract with different clinical presentations. These chronic inflammatory diseases are associated with an increased risk for both intestinal and different types of extra-intestinal malignancies. In this case report, we describe the condition of a 29-year-old Saudi male diagnosed with fistulizing ileal Crohn's disease 7 years ago. Read More

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Preoperative embolization of renal cell carcinoma prior to partial nephrectomy: A systematic review and meta-analysis.

Clin Imaging 2021 May 3;76:205-212. Epub 2021 May 3.

Division of Vascular and Interventional Radiology, Department of Radiology, Rutgers - New Jersey Medical School, 185 South Orange Ave. MSB F-560, Newark, NJ 07103, United States of America. Electronic address:

Purpose: To evaluate the safety and efficacy of preoperative renal artery embolization of renal cell carcinoma in reducing intraoperative blood loss during subsequent partial nephrectomy through a systematic review and meta-analysis of current literature.

Materials And Methods: The PubMed database was searched for articles published from 1970 to 2018 describing patients with renal cell carcinoma who underwent partial nephrectomy with and without preoperative embolization of the tumor. Demographic data, procedural techniques, and surgical outcomes were obtained when available. Read More

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Validation of a German translation of the CARE questionnaire and its implementation as electronic PROM to assess patient-reported postoperative convalescence and recovery after major urological surgery.

World J Urol 2021 May 8. Epub 2021 May 8.

Department of Urology and Urological Surgery, Medical Faculty, University Medical Center Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

Purpose: To validate a German translation of the convalescence and recovery evaluation (CARE) as an electronic patient-reported outcome measure (ePROM) and use it to assess recovery after major urological surgery.

Methods: The CARE questionnaire was provided to patients scheduled for major urological surgery preoperatively, at discharge and 6 weeks postoperatively, using an ePROM system. Cronbach's alpha, inter-scale correlations and confirmatory factor analysis (CFA) were used to validate the translation. Read More

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Robot-Assisted Laparoscopic Partial Nephrectomy for Allograft Renal Cell Carcinoma: A Case Report.

Transplant Proc 2021 May 4. Epub 2021 May 4.

Department of Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan.

Background: Nephron-sparing surgery is required for patients with kidney transplant with organ-confined renal cell carcinoma (RCC) in the allograft kidney to preserve renal function. Robot-assisted laparoscopic partial nephrectomy (RAPN) is expected to be the optimal surgical approach for these patients, as in the general population. However, RAPN for RCC arising in the allograft kidney is rarely reported. Read More

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Unplanned open conversion during radical or partial nephrectomy: Comparing outcomes and trends.

Urology 2021 May 4. Epub 2021 May 4.

Division of Urology, Department of Surgery, Saint Louis University, St Louis, MO. Electronic address:

Objectives: To compare perioperative outcomes between open conversion and planned open surgical approach and to investigate trends.

Materials And Methods: The National Cancer Database (NCDB) was queried for cT1 and cT2 RCC treated by radical (RN) or partial (PN) nephrectomy between 2010 and 2016. We retrospectively analyzed patient demographics, clinical tumor characteristics, and perioperative outcomes between unplanned open conversion and planned open approaches for RN and PN. Read More

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Low-Grade Oncocytic Tumor of Kidney (CK7-Positive, CD117-Negative): Incidence in a Single Institutional Experience with Clinicopathological and Molecular Characteristics.

Hum Pathol 2021 May 4. Epub 2021 May 4.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905. Electronic address:

Aims: Low-grade oncocytic tumor of the kidney (LOT) is characterized by cytoplasmic eosinophilia and a CK7-positive/CD117-negative immunophenotype. Morphologically, they exhibit overlapping features with oncocytoma and chromophobe renal cell carcinoma (chRCC). Our aim was to obtain long-term clinical follow-up data, clinicopathological and molecular characteristics, and incidence of LOT. Read More

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[Unilateral combination of staghorn stone with kidney tumor].

A D Kochkin

Urologiia 2021 May(2):106-108

Privolzhskiy Research Medical University, Nizhny Novgorod, Russia.

This manuscript provides an overview of the available literature about unilateral combination of nephrolithiasis and renal tumor. Analysis of publications has shown that ipsilateral staghorn calculus and kidney tumors are an extremely rare combination. The majority of these infrequent papers describe case reports where the method of treating such patients is limited by the capabilities and competence of the surgeon or clinic. Read More

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Predicting Complications After Robotic Partial Nephrectomy: Back to Simplicity.

Eur Urol Focus 2021 May 3. Epub 2021 May 3.

Department of Urology, Rennes University Hospital, Rennes, France.

Background: Robotic partial nephrectomy (RPN) has a significant morbidity. Nephrometry scores have been described to predict the occurrence of complications. Their usefulness is debated. Read More

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Surgical management of horseshoe kidney tumors. Literature review and analysis of two cases.

Actas Urol Esp 2021 May 3. Epub 2021 May 3.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction: The horseshoe kidney is a rare congenital anomaly in the general population that combines renal ectopia, malrotation and abnormal vascular supply. The most frequently developed tumor in this case is renal cell carcinoma (50%). One of its main characteristics is great anatomical variation, especially in terms of vascular structures. Read More

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CircEHD2, CircNETO2 and CircEGLN3 as Diagnostic and Prognostic Biomarkers for Patients with Renal Cell Carcinoma.

Cancers (Basel) 2021 Apr 30;13(9). Epub 2021 Apr 30.

Department of Urology, University Hospital Bonn, 53127 Bonn, Germany.

Background: Circular RNA (circRNA) plays an important role in the carcinogenesis of various tumors. It is assumed that circRNAs have a high tissue and tumor specificity, thus they are discussed as cancer biomarkers. The knowledge about circRNAs in clear cell renal carcinoma (ccRCC) is limited so far, and thus we studied the expression profile of seven circRNAs (circCOL5A1, circEHD2, circEDEM2, circEGNL3, circNETO2, circSCARB1, circSOD2) in a cohort of ccRCC patients. Read More

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Partial nephrectomy in frail patients: Benefits of robot-assisted surgery.

Surg Oncol 2021 Apr 22;38:101588. Epub 2021 Apr 22.

Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montreal Health Center, Montreal, Quebec, Canada.

Background: To compare the effect of robot-assisted (RAPN) vs. open (OPN) partial nephrectomy on short-term postoperative outcomes and total hospital charges in frail patients with non-metastatic renal cell carcinoma (RCC).

Methods: Within the National Inpatient Sample database we identified 2745 RCC patients treated with either RAPN or OPN between 2008 and 2015, who met the Johns Hopkins Adjusted Clinical Groups frailty-defining indicator criteria. Read More

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Association of Ancillary Pathology Findings in Non-neoplastic Renal Parenchyma and Renal Outcomes of Robotic-Assisted Partial Nephrectomy.

Front Surg 2021 16;8:652524. Epub 2021 Apr 16.

Department of Urology, Mayo Clinic, Jacksonville, FL, United States.

To evaluate robotic-assisted partial nephrectomy (RAPN) renal outcomes associated with ancillary pathology findings in non-neoplastic renal parenchymal tissue. Tissue samples from 378 RAPNs were analyzed for glomerular disease (GD), vascular disease (VD), and tubulointerstitial disease (TD). One hundred and fifty-two patients were excluded due to insufficient non-neoplastic tissue for analysis and 4 patients were excluded due to calyceal diverticulum. Read More

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Evolution of renal cyst to renal carcinoma: a case report and review of literature.

Int J Clin Exp Pathol 2021 15;14(4):463-468. Epub 2021 Apr 15.

Department of Urology, The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University 66 Zhongshan Road, Wuxi 214000, Jiangsu, People's Republic of China.

Background: Renal cyst is a common benign disease which is rare to progress from simple renal cyst to renal cell carcinoma.

Case Presentation: A 62-year-old woman who suffered a simple renal cyst for over 20 years complained intermittent lumbar in recent 2 years. At her latest admission, the cyst lesion displayed enhancement in the cystic wall by CT scan and cystic to partially solid change by ultrasound, so we did a partial nephrectomy and found that the cystic lesion had become a cyst-solid transition. Read More

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Can we Avoid the Unnecessary Loss of nephrons in the Management of Small Solid Renal Masses? Additional Clinical Parameters to Predict Benign-malign Distinction.

Sisli Etfal Hastan Tip Bul 2021 17;55(1):53-61. Epub 2021 Mar 17.

Department of Urology, University of Health Science Turkey, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey.

Objectives: We aimed to investigate the predictive value of additional parameters for distinguishing benign-malign tumors and to prevent the loss of nephrons in small (≤4 cm) solid renal masses.

Methods: The data of 56 patients underwent partial or radical nephrectomy between September 2009 and December 2017 due to diagnosis of localized renal cell carcinoma were retrospectively analyzed. Demographic datas, histopathological tumor types, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), platelet/lymphocyte ratio (PLR), red blood cell distribution width (RDW), mean platelet volume (MPV), the Framingham risk score and its components, postoperative follow-up results were recorded. Read More

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Genetic profile and immunohistochemical study of clear cell renal carcinoma: Pathological-anatomical correlation and prognosis.

Cancer Treat Res Commun 2021 Apr 18;27:100374. Epub 2021 Apr 18.

Department of Urology. Hospital Clínico Universitario de Valencia, Av. Blasco Ibáñez, 17, 46010. Valencia- España. Electronic address:

Introduction: Renal cell carcinoma (RCC) accounts for 2-3% of all tumors being the most frequent solid lesion in the kidney.

Objective: To determine what genetic alterations and immunohistochemical (IHC) of clear cell renal carcinoma (ccRCC) are associated with prognosis and tumor aggressiveness.

Patients And Methods: Experimental analytical study with 57 patients who underwent radical and partial nephrectomy between 2005 and 2011, all with diagnosis of ccRCC and minimum post-operative follow-up of 36 months. Read More

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Retroperitoneal or transperitoneal approach in robot-assisted partial nephrectomy, which one is better?

Cancer Med 2021 May 1. Epub 2021 May 1.

Department of Urology, West China Hospital, Sichuan University, Chengdu, China.

Purpose: To systematically assess the perioperative outcomes of retroperitoneal (RP) and transperitoneal (TP) approaches in robot-assisted partial nephrectomy (RAPN), we conducted an updated meta-analysis.

Methods: A literature retrieval of multi-database including PubMed, Web of Science, Embase, Cochrane Library, and CNKI was performed to identify eligible comparative studies from the inception dates to January 2021. Perioperative outcomes included operative time (OT), estimated blood loss (EBL), warm ischemia time (WIT), postoperative length of stay (PLOS), positive surgical margin (PSM), and complications (major complications and overall complications). Read More

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Superselective Ischemia in Robotic Partial Nephrectomy Does Not Provide Better Long-term Renal Function than Renal Artery Clamping in a Randomized Controlled Trial (EMERALD): Should We Take the Risk?

Eur Urol Focus 2021 Apr 27. Epub 2021 Apr 27.

Urology Department, Grenoble University Hospital, Grenoble, France.

Background: Superselective clamping of tumor-targeted arteries aims to eliminate ischemia of the remnant kidney while keeping tumor bed bloodless during excision.

Objective: To evaluate the impact of superselective clamping on long-term renal function, compared with renal artery early unclamping.

Design, Setting, And Participants: A randomized monocentric single-blind trial (1:1) was conducted from February 2018 to August 2019. Read More

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Use of Pre-Operative Pharmacologic Venous Thromboembolism Prophylaxis for Robotic Partial Nephrectomy.

Urology 2021 Apr 27. Epub 2021 Apr 27.

UT Southwestern Department of Urology, 2001 Inwood Dr, WCB3 building, Dallas, Texas 75390.

Objectives: To determine whether a single dose of pre-operative enoxaparin for venous thromboembolism (VTE) prophylaxis impacts rates of thrombotic and bleeding events after robotic partial nephrectomy (RPNx).

Methods: A retrospective cohort study of RPNx patients from 2009-2020 was performed. Clinical characteristics and peri-operative outcomes were compared between patients receiving a single dose of pre-operative enoxaparin and those who did not. Read More

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Irreversible Electroporation for the Treatment of Small Renal Masses: 5-Year Outcomes.

J Endourol 2021 Apr 30. Epub 2021 Apr 30.

UT Southwestern, 12334, Urology, Dallas, Texas, United States;

Introduction: Irreversible electroporation (IRE) is a nonthermal ablative technology that applies high voltage, short pulse electrical current to create cellular membrane nanopores and ultimately results in apoptosis. This is thought to overcome thermal limitations of other ablative technologies. We report 5-year oncologic outcomes of percutaneous IRE for small renal masses. Read More

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Usefulness of Thulium-Doped Fiber Laser and Diode Laser in Zero Ischemia Kidney Surgery-Comparative Study in Pig Model.

Materials (Basel) 2021 Apr 16;14(8). Epub 2021 Apr 16.

Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University, Bujwida 44, 50-368 Wroclaw, Poland.

Background: The aim of this study was to evaluate the usefulness of a thulium-doped fiber laser and a diode laser in zero ischemia kidney surgery, by carrying out a comparative study in a pig model.

Material And Methods: Research was carried out on 12 pigs weighing 30 kg each. A thulium-doped fiber laser (TDFL) and a diode laser (DL) operating at wavelengths of 1940 and 1470 nm, respectively, were used. Read More

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Comparison of Robot-Assisted Laparoscopic Partial Nephrectomy with Laparoscopic Cryoablation in the Treatment of Localised Renal Tumours: A Propensity Score-Matched Comparison of Long-Term Outcomes.

Diagnostics (Basel) 2021 Apr 23;11(5). Epub 2021 Apr 23.

Department of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

Preserving renal function and controlling oncological outcomes are pertinent when managing renal neoplasms. Cryoablation is the recommended treatment only for clinical T1a stage renal tumour. Here, we compared the outcomes of robot-assisted laparoscopic partial nephrectomy (RaPN) and laparoscopic cryoablation (LCA) in the treatment of patients with localised T1-T2 renal tumours. Read More

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The Effect of Remote Ischemic Preconditioning on Serum Creatinine in Patients Undergoing Partial Nephrectomy: A Randomized Controlled Trial.

J Clin Med 2021 Apr 12;10(8). Epub 2021 Apr 12.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, College of Medicine, Seoul National University, 101 Daehak-Ro, Jongno-Gu, Seoul 03080, Korea.

Renal function declines after partial nephrectomy due to ischemic reperfusion injury induced by surgical insult or renal artery clamping. The effect of remote ischemic preconditioning (RIPC) on reducing renal injury after partial nephrectomy has not been studied regarding urinary biomarkers. Eighty-one patients undergoing partial nephrectomy were randomly assigned to either RIPC or the control group. Read More

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Predicting operation time and creating a difficulty scoring system in donor nephrectomy.

J Endourol 2021 Apr 29. Epub 2021 Apr 29.

Kyushu University, 12923, Department of Surgery and Oncology, Graduate School of Medical Sciences, Fukuoka, Japan;

Background: To determine predictive formulas for operation time and surgical difficulty in laparoscopic living-donor kidney transplantation.

Methods: We retrospectively analyzed data for 222 living donors aged > 20 years and recorded factors affecting operation time from patients' computed tomography images and medical records. We used the factors significantly affecting operation time to create a formula to predict operation time and designed a model to predict surgical difficulty based on the standardized partial regression coefficient, β. Read More

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Therapeutic and Clinical Outcomes of Robot-assisted Partial Nephrectomy Cryoablation for T1 Renal Cell Carcinoma.

In Vivo 2021 May-Jun;35(3):1573-1579

Department of Urology, Osaka University Graduate School of Medicine, Osaka, Japan.

Background: In cT1 renal cell carcinoma (RCC), very few studies have compared oncological outcomes and renal function preservation rates in nephron-sparing robot-assisted partial nephrectomy (RAPN) and percutaneous cryoablation (PCA).

Patients And Methods: We retrospectively analysed 126 patients with cT1 RCC treated with RAPN (n=78) and computed tomography-guided PCA (n=48) between March 2016 and November 2019. Clinical data and outcomes were compared for the two groups. Read More

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January 2021

Role of SIRT1/AMPK signaling in the proliferation, migration and invasion of renal cell carcinoma cells.

Oncol Rep 2021 Jun 28;45(6). Epub 2021 Apr 28.

Department of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, P.R. China.

Renal cell carcinoma (RCC) is a lethal urologic tumor commonly seen in men that best responds to partial nephrectomy. An enhanced understanding of the molecular pathogenesis of RCC can broaden treatment options and tumor prevention strategies. Sirtuin 1 (SIRT1) is a NAD+‑dependent deacetylase that regulates several bioactive substances, and the present study aimed to identify the role of SIRT1/AMP‑activated protein kinase (AMPK) signaling in RCC progression. Read More

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Reoperative Partial Nephrectomy: Does Previous Surgical Footprint Impact Outcomes?

J Urol 2021 Apr 27:101097JU0000000000001837. Epub 2021 Apr 27.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, Maryland.

Purpose: Historically, open techniques have been favored over minimally invasive approaches for complex surgeries. We aimed to identify differences in perioperative outcomes, surgical footprints, and complication rates in patients undergoing either open or robotic reoperative partial nephrectomies (RePN).

Materials And Methods: A retrospective review of patients undergoing RePN was performed. Read More

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Three-dimensional Virtual Models' Assistance During Minimally Invasive Partial Nephrectomy Minimizes the Impairment of Kidney Function.

Eur Urol Oncol 2021 Apr 23. Epub 2021 Apr 23.

Division of Urology, Department of Oncology, School of Medicine, University of Turin, San Luigi Hospital, Orbassano (Turin), Italy.

Three-dimensional virtual models (3DVMs) are nowadays under scrutiny to improve partial nephrectomy (PN) outcomes. This report aims to analyze their impact on renal function preservation after minimally invasive PN. A total of 100 patients treated with minimally invasive PN with contrast-enhanced computed tomography from which a 3DVM was obtained, and having undergone baseline and 3rd month postoperative renal scans were prospectively enrolled and compared with a control group of 251 patients without 3DVMs. Read More

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