5,924 results match your criteria neonatal ecg

Automated Medical Care: Bradycardia Detection and Cardiac Monitoring of Preterm Infants.

Medicina (Kaunas) 2021 Nov 3;57(11). Epub 2021 Nov 3.

Fundamentals of Physics for Engineers Department, "Politehnica" University Timisoara, Bd. Vasile Pârvan 2, 300223 Timisoara, Romania.

: Prematurity of birth occurs before the 37th week of gestation and affects up to 10% of births worldwide. It is correlated with critical outcomes; therefore, constant monitoring in neonatal intensive care units or home environments is required. The aim of this work was to develop solutions for remote neonatal intensive supervision systems, which should assist medical diagnosis of premature infants and raise alarm at cardiac abnormalities, such as bradycardia. Read More

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November 2021

Gestational Age and Neonatal Electrocardiograms.

Pediatrics 2021 Nov 24. Epub 2021 Nov 24.

Department of Cardiology, Herlev-Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark.

Objectives: Interpretation of the neonatal electrocardiogram (ECG) is challenging due to the profound changes of the cardiovascular system in this period. We aimed to investigate the impact of gestational age (GA) on the neonatal ECG and create GA-specific reference values.

Methods: The Copenhagen Baby Heart Study is a prospective general population study that offered cardiac evaluation of neonates. Read More

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November 2021

Impact of maternal obesity on neonatal heart rate and cardiac size.

Arch Dis Child Fetal Neonatal Ed 2021 Nov 17. Epub 2021 Nov 17.

Women's and Children's Health, King's College London, London, UK.

Background: Maternal obesity may increase offspring risk of cardiovascular disease. We assessed the impact of maternal obesity on cardiac structure and function in newborns as a marker of fetal cardiac growth.

Methods: Neonates born to mothers of healthy weight (body mass index (BMI) 20-25 kg/m, n=56) and to mothers who were obese (BMI ≥30 kg/m, n=31) underwent 25-minute continuous ECG recording and non-sedated, free-breathing cardiac MRI within 72 hours of birth. Read More

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November 2021

Complete heart block in neonatal lupus: a forgotten cause of fetal bradycardia.

BMJ Case Rep 2021 Nov 16;14(11). Epub 2021 Nov 16.

Neonatal Intensive Care Unit, Calmette Hospital, Phnom Penh, Cambodia.

The most common cause of congenital heart block (CHB) is neonatal lupus, an acquired autoimmune disease caused by transplacental transfer of maternal antibodies to the fetus. A full-term female neonate was admitted to neonatal intensive care unit for severe bradycardia with stable haemodynamics. The mother, showing no clinical symptoms or any particular history, was transferred to our tertiary centre for profound fetal bradycardia. Read More

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November 2021

Assessing patent ductus arteriosus in preterm infants from standard neonatal intensive care monitoring.

Eur J Pediatr 2021 Nov 8. Epub 2021 Nov 8.

Department of Women's and Children's Health, University of Liverpool, Liverpool Health Partners, Liverpool, UK.

Monitoring patent ductus arteriosus (PDA) in premature infants is currently performed intermittently using echocardiography which requires considerable expertise. The aim of this pilot study was to investigate whether PDA status could be assessed from standard neonatal intensive care monitoring. Electrocardiography (ECG) and blood pressure (BP) waveforms were acquired from extremely preterm infants using standard neonatal monitors. Read More

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November 2021

A Pilot Randomized Trial of Heart Rate Monitoring Using Conventional Versus a New ECG Algorithm During Neonatal Resuscitation at Birth.

J Pediatr 2021 Oct 26. Epub 2021 Oct 26.

Neonatal Research Institute, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, United States of America.

Current guidelines support the use of a cardiac monitor during neonatal resuscitation. Preterm infants randomized to a novel ECG algorithm displayed a heart rate sooner than the conventional ECG algorithm. Although resuscitation outcomes were not different, availability of an earlier heart rate may benefit neonatal providers during high-risk resuscitations. Read More

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October 2021

Electrocardiogram for heart rate evaluation during preterm resuscitation at birth: a randomized trial.

Pediatr Res 2021 Oct 13. Epub 2021 Oct 13.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Background: Although electrocardiogram (ECG) can detect heart rate (HR) faster compared to pulse oximetry, it remains unknown if routine use of ECG for delivery room (DR) resuscitation reduces the time to stabilization in preterm infants.

Methods: Neonates <31 weeks' gestation were randomized to either an ECG-displayed or an ECG-blinded HR assessment in the DR. HR, oxygen saturation, resuscitation interventions, and clinical outcomes were compared. Read More

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October 2021

Automated Detection and Removal of Cardiac and Pulse Interferences from Neonatal EEG Signals.

Sensors (Basel) 2021 Sep 23;21(19). Epub 2021 Sep 23.

Behavioral Imaging and Neural Dynamics Center, G. d'Annunzio University of Chieti-Pescara, 66100 Chieti, Italy.

Electrical cardiac and pulsatile interference is very difficult to remove from electroencephalographic (EEG) signals, especially if recorded in neonates, for which a small number of EEG channels is used. Several methods were proposed, including Blind Source Separation (BSS) methods that required the use of artificial cardiac-related signals to improve the separation of artefactual components. To optimize the separation of cardiac-related artefactual components, we propose a method based on Independent Component Analysis (ICA) that exploits specific features of the real electrocardiographic (ECG) signals that were simultaneously recorded with the neonatal EEG. Read More

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September 2021

[Research on Patient Monitoring Alarms in ICU and NICU].

Zhongguo Yi Liao Qi Xie Za Zhi 2021 Sep;45(5):585-590

Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518000.

Objective: The patient monitors were used to explore the alarm actuality in a ICU and NICU to investigate the awareness and reaction of medical staff to alarms.

Methods: A series of surveys and interviews were taken to acquire clinicians' feelings and attitudes to monitoring alarms. The researchers were scheduled to track the alarms with annotations, and collect the alarm data of patient monitors using central monitoring system. Read More

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September 2021

Emergency treatment of thrombus in right coronary artery and aortic root in a newborn with acute myocardial infarction.

Turk Gogus Kalp Damar Cerrahisi Derg 2021 Jul 26;29(3):395-398. Epub 2021 Jul 26.

Department of Pediatric Cardiology, Başakşehir Cam and Sakura City Hospital, Istanbul, Turkey.

Perinatal myocardial infarction caused by aortic root and coronary artery thrombosis in neonatal period is extremely rare and has a gloomy prognosis that may cause devastating complications. A 3-h newborn baby who had acute myocardial infarction findings on postnatal electrocardiography had a thrombus in the aortic root with hyperechogenic right coronary artery region, and impaired right ventricular functions on echocardiography. The patient was urgently operated and thrombus was successfully removed from the aortic root and the right coronary artery. Read More

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Multiscale Entropy Analysis of Heart Rate Variability in Neonatal Patients with and without Seizures.

Bioengineering (Basel) 2021 Sep 9;8(9). Epub 2021 Sep 9.

Department of Information Engineering, Università degli Studi di Firenze, Via Santa Marta 3, 50139 Firenze, Italy.

The complex physiological dynamics of neonatal seizures make their detection challenging. A timely diagnosis and treatment, especially in intensive care units, are essential for a better prognosis and the mitigation of possible adverse effects on the newborn's neurodevelopment. In the literature, several electroencephalographic (EEG) studies have been proposed for a parametric characterization of seizures or their detection by artificial intelligence techniques. Read More

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September 2021

Centrally Administered Neuropeptide-S Alleviates Gastrointestinal Dysmotility Induced by Neonatal Maternal Separation.

Neurogastroenterol Motil 2021 Sep 24:e14269. Epub 2021 Sep 24.

Department of Physiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Background: Neuropeptide-S (NPS) regulates autonomic outflow, stress response, and gastrointestinal (GI) motor functions. This study aimed to investigate the effects of NPS on GI dysmotility induced by neonatal maternal separation (MS).

Methods: MS was conducted by isolating newborn pups from dams from postnatal day 1 to day 14. Read More

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September 2021

Third Trimester Fetal Heart Rates in Antibody-Mediated Complete Heart Block Predict Need for Neonatal Pacemaker Placement.

Pediatr Cardiol 2021 Sep 12. Epub 2021 Sep 12.

Division of Pediatric Cardiology, Children's Hospital of Los Angeles, Keck School of Medicine at University of Southern California, 4650 W Sunset Boulevard, MS #34, Los Angeles, CA, 90027, USA.

Congenital complete heart block (CCHB) affects 1 in 20,000 newborns. This study evaluates fetal and neonatal risk factors predictive of neonatal pacemaker placement in antibody-mediated complete heart block. The Children's Hospital Los Angeles institutional fetal, pacemaker, and medical record databases were queried for confirmed SSA/SSB cases of CCHB between January 2004 and July 2019. Read More

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September 2021

Mexiletine Treatment for Neonatal LQT3 Syndrome: Case Report and Literature Review.

Front Pediatr 2021 24;9:674041. Epub 2021 Aug 24.

Pediatric Cardiology Unit, Department of Pediatrics, School of Medicine, University Hospital Heraklion, University of Crete, Heraklion, Greece.

Early diagnosis of long QT type 3 (LQT3) syndrome during the neonatal period is of paramount clinical importance. LQT3 syndrome results in increased mortality and a mutation-specific response to treatment compared to other more common types of LQT syndrome. Mexiletine, a sodium channel blocker, demonstrates a mutation-specific QTc shortening effect in LQT3 syndrome patients. Read More

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miR-195-5p regulates cell proliferation, apoptosis, and invasion of thyroid cancer by targeting telomerase reverse transcriptase.

Bioengineered 2021 12;12(1):6201-6209

Department Of Head And Neck Surgery, Jiangxi Provincial Cancer Hospital, Jiangxi Cancer Hospital of Nanchang University, Jiangxi Provincial Key Laboratory of Translational Medicine and Oncology, Jiangxi Cancer Center, Nanchang, Jiangxi, China.

In most human primary cancers, the expression, or telomerase activity, of telomerase reverse transcriptase () is detectable. However, the mechanism ofactivity within oncogenesis of thyroid cancer remains largely unknown. In this study, we identified miR-195-5p as having involvement in cell proliferation, apoptosis, and invasion in human thyroid cancer. Read More

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December 2021

Non-Contact Automatic Vital Signs Monitoring of Infants in a Neonatal Intensive Care Unit Based on Neural Networks.

J Imaging 2021 Jul 23;7(8). Epub 2021 Jul 23.

UniSA STEM, Mawson Lakes Campus, University of South Australia, Mawson Lakes, SA 5095, Australia.

Infants with fragile skin are patients who would benefit from non-contact vital sign monitoring due to the avoidance of potentially harmful adhesive electrodes and cables. Non-contact vital signs monitoring has been studied in clinical settings in recent decades. However, studies on infants in the Neonatal Intensive Care Unit (NICU) are still limited. Read More

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Benchmarking Transfer Entropy Methods for the Study of Linear and Nonlinear Cardio-Respiratory Interactions.

Entropy (Basel) 2021 Jul 23;23(8). Epub 2021 Jul 23.

STADIUS, Center of Dynamical Systems, Signal Processing and Data Analytics, Department of Electrical Engineering (ESAT), KU Leuven, 3001 Leuven, Belgium.

Transfer entropy (TE) has been used to identify and quantify interactions between physiological systems. Different methods exist to estimate TE, but there is no consensus about which one performs best in specific applications. In this study, five methods (linear, k-nearest neighbors, fixed-binning with ranking, kernel density estimation and adaptive partitioning) were compared. Read More

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Torsade de pointe due to QT prolongation following erythromycin administration in a preterm infant.

Acta Cardiol 2021 Aug 23:1-5. Epub 2021 Aug 23.

Department of Neonatology, Cliniques Universitaires Saint Luc, Bruxelles, Belgium.

Background: Neonatal sepsis is a major cause of morbidity and mortality in preterm infants. Chorioamnionitis is an important risk factor for the development of sepsis, therefore neonates born to mothers developing signs of amnionitis need to be treated with antibiotics immediately after birth. spp can be a causative agent of vaginal or intra amniotic infection needing antibiotic treatment. Read More

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Acute Respiratory Distress Syndrome due to COVID-19 during Pregnancy.

Neoreviews 2021 08;22(8):e551-e558

Beth Israel Deaconess Medical Center, Boston, MA.

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Recurrent Atrial Flutter Requiring Multiple Cardioversions in a Preterm Infant.

JACC Case Rep 2021 Apr 21;3(4):630-632. Epub 2021 Apr 21.

Division of Pediatric Cardiology, Children's Hospital at Montefiore, Bronx, New York, USA.

We describe the first case of atrial flutter requiring multiple cardioversions in a preterm infant. Direct current cardioversion is one of the best-understood treatment options, with a first-time success rate higher than 96%. The electrocardiograms provided reveal a second run of atrial flutter occurring after successful cardioversion. Read More

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An E-Textile Respiration Sensing System for NICU Monitoring: Design and Validation.

J Signal Process Syst 2021 Jul 17:1-15. Epub 2021 Jul 17.

Department of Electrical, Computer, and Biomedical Engineering, University of Rhode Island, Kingston, RI USA.

The world is witnessing a rising number of preterm infants who are at significant risk of medical conditions. These infants require continuous care in Neonatal Intensive Care Units (NICU). Medical parameters are continuously monitored in premature infants in the NICU using a set of wired, sticky electrodes attached to the body. Read More

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Adapted ST analysis during labor: relative versus absolute ST events, a case-control study.

J Matern Fetal Neonatal Med 2021 Jul 25:1-6. Epub 2021 Jul 25.

Department of Obstetrics and Gynecology, Máxima Medical Center, Veldhoven, The Netherlands.

Background: The value of ST analysis of the fetal electrocardiogram during labor to lower asphyxia and cesarean section rates is uncertain. Physiological variation of the electrical heart axis between fetuses may explain false alarms in conventional ST analysis (absolute ST analysis). ST events (alarms) based on relative T/QRS rises (relative ST analysis) correct for this variation and may improve diagnostic accuracy of ST analysis. Read More

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Focused echocardiography, end-tidal carbon dioxide, arterial blood pressure or near-infrared spectroscopy monitoring during paediatric cardiopulmonary resuscitation: A scoping review.

Resusc Plus 2021 Jun 30;6:100109. Epub 2021 Mar 30.

Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom.

Aim: To evaluate the individual use and predictive value of focused echocardiography, end-tidal carbon dioxide (EtCO), invasive arterial blood pressure (BP) and near-infrared spectroscopy (NIRS) during cardiopulmonary resuscitation (CPR) in children.

Methods: This scoping review was undertaken as part of the continuous evidence evaluation process of the International Liaison Committee on Resuscitation (ILCOR) and based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) extension for scoping reviews. PubMed, MEDLINE, CINAHL and EMBASE were searched from the last ILCOR reviews until September 2020. Read More

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Supraventricular tachycardias in neonates and infants: factors associated with fatal or near-fatal outcome.

Eur J Pediatr 2021 Aug 29;180(8):2669-2676. Epub 2021 Jun 29.

Gottsegen György Hungarian Institute of Cardiology, Budapest, Hungary.

Prognosis of supraventricular tachycardias in neonates and infants is thought to be excellent with rare fatal outcomes. Nevertheless, initial management can be challenging. The aim of this study was to perform a retrospective analysis in neonates/infants with non-pos-toperative supraventricular tachycardias regarding risk factors for clinical outcome and type of antiarrhythmic drug therapy. Read More

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Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo.

Cell Mol Biol (Noisy-le-grand) 2020 Dec 31;66(8):9-13. Epub 2020 Dec 31.

Department of Obstetrics, Jiaozhou Central Hospital, Qingdao 266300, China.

This study aimed to evaluate the maternal and fetal results in women undergoing antihypertensive therapy (low aspirin or labetalol) with mild to severe chronic hypertension relative to women without medicines. This randomized multi-center clinical trial was performed with random division into three groups of 393 pregnant women with mild to moderate chronic hypertension. From the beginning of the pregnancy to the end of the puerperium, the low dosage aspirin group (n = 129), the labetalol group (n = 127), and the drug-free or control group (n = 126) reported both mother and child results. Read More

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December 2020

Neonatal Arrhythmia.

A Joshi S Humagain

Kathmandu Univ Med J (KUMJ) 2020 Oct.-Dec.;18(72):430-433

Department of Medicine, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

Arrhythmias are seldom observed in the newborn period and rarely lead to serious consequences. Because they may be a continuation of fetal arrhythmias, newborn arrhythmias are different from those occurring at later ages. Here we describe a case of a newborn presented with tachycardia at birth. Read More

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Functional Calsequestrin-1 Is Expressed in the Heart and Its Deficiency Is Causally Related to Malignant Hyperthermia-Like Arrhythmia.

Circulation 2021 Sep 24;144(10):788-804. Epub 2021 Jun 24.

Department of Pharmacology, School of Basic Medical Sciences, Beijing Key Laboratory of Metabolic Disturbance Related Cardiovascular Disease (Z.S., L.W., Q.L., S.T., L.W., R.L., Z.F., H.Y., Y. Zheng, D.L.)., Beijing Anzhen Hospital, Capital Medical University, P. R. China.

Background: Calsequestrins (Casqs), comprising the Casq1 and Casq2 isoforms, buffer Ca and regulate its release in the sarcoplasmic reticulum of skeletal and cardiac muscle, respectively. Human inherited diseases associated with mutations in or include malignant hyperthermia/environmental heat stroke (MH/EHS) and catecholaminergic polymorphic ventricular tachycardia. However, patients with an MH/EHS event often experience arrhythmia for which the underlying mechanism remains unknown. Read More

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September 2021


Wiad Lek 2021 ;74(6):1349-1354


Objective: The aim: Analysis of electrocardiographic parameters in newborns from mothers with metabolic syndrome.

Patients And Methods: Materials and methods: We conducted a prospective cohort trial of 125 newborns, which included the study of their anthropometric, clinical and laboratory indicators and, in particular, ECG parameters. The main group consisted of 40 children, born from mothers with diagnosed metabolic syndrome, the comparison group included 2 subgroups: 28 term newborn and 57 preterm, from mothers without metabolic syndrome. Read More

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Respiratory support after delayed cord clamping: a prospective cohort study of at-risk births at ≥35 weeks gestation.

Arch Dis Child Fetal Neonatal Ed 2021 Nov 10;106(6):627-634. Epub 2021 Jun 10.

Newborn Research Centre, Royal Women's Hospital, Parkville, Victoria, Australia.

Objective: To identify risk factors associated with delivery room respiratory support in at-risk infants who are initially vigorous and received delayed cord clamping (DCC).

Design: Prospective cohort study.

Setting: Two perinatal centres in Melbourne, Australia. Read More

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November 2021

[RCT of Reduction in Catheter-Related Complications by Using Intracavitary Electrocardiogram-Assisted Guidance in Neonatal PICC Placement].

Sichuan Da Xue Xue Bao Yi Xue Ban 2021 May;52(3):497-502

Department of Pediatrics, School of Medicine, University of Electronic Science and Technology of China/Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu 610072, China.

Objective: To investigate the effect of intracavitary electrocardiogram (IC-ECG) guidance on peripherally inserted central catheter (PICC) related complications in neonatal patients.

Methods: A total of 210 neonatal patients were included in the study. They were admitted to the Neonatal Intensive Care Unit, Sichuan Provincial People's Hosptial between January, 2017 and December, 2019 and had PICC lines were placed in their upper limbs. Read More

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