482 results match your criteria neem extract

Leaf Extract as Green Corrosion Inhibitor for Reinforced Concrete Structures: Corrosion Effectiveness against Commercial Corrosion Inhibitors and Concrete Integrity.

Materials (Basel) 2021 Jun 16;14(12). Epub 2021 Jun 16.

Laboratorio de Corrosión y Materiales, Instituto de Ingeniería, Universidad Autónoma de Baja California, Blvd. Benito Juárez y Calle de la Normal s/n, Mexicali C.P. 21040, Baja California, Mexico.

The construction industry has extensively demanded novel green inhibition strategies for the conservation and protection of carbon steel-reinforced concrete structures. For the first time, the effect of Azadirachta indica leaf extract (Neem) as a potential corrosion inhibitor of carbon steel in reinforced concrete under corrosion in saline simulated media was evaluated. To assess the corrosion inhibition behavior of the Neem natural organic extract, three inorganic commercial inhibitors were tested to compare following the criteria established by Stratful for half-cell potential under a simulated chloride environment. Read More

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Functional Properties of Antimicrobial Neem Leaves Extract Based Macroalgae Biofilms for Potential Use as Active Dry Packaging Applications.

Polymers (Basel) 2021 May 20;13(10). Epub 2021 May 20.

Department of Mechanical Engineering, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.

Antimicrobial irradiated seaweed-neem biocomposite films were synthesized in this study. The storage functional properties of the films were investigated. Characterization of the prepared films was conducted using SEM, FT-IR, contact angle, and antimicrobial test. Read More

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Plant Leaves Extract Irrigation on Wound Healing in Diabetic Foot Ulcers.

Evid Based Complement Alternat Med 2021 11;2021:9924725. Epub 2021 May 11.

Saveetha Institute of Medical and Technical Sciences, Chennai, India.

Purpose: We aimed to evaluate and compare the efficacy of neem leaves extract with normal saline irrigation practice in wound dressing on healing outcome and clinic-physiological parameters among individuals with diabetic foot ulcer (DFU).

Methods: A quasiexperimental with repeated measures design was used on two study groups. One group received neem leaf extract wound irrigation and another group received normal saline wound irrigation. Read More

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Environmental friendly sustainable application of plant-based mordants for cotton dyeing using Arjun bark-based natural colorant.

Environ Sci Pollut Res Int 2021 May 27. Epub 2021 May 27.

Applied Chemistry Research Centre, PCSIR Laboratories Complex, Ferozepur Road, Lahore, Pakistan.

Ecofriendly exploration of Arjun bark (Terminalia arjuna) is a herbal natural colorant for cotton dyeing. This is because the demand for natural dyes has been increased worldwide due to their therapeutic usage and other food, textiles, agriculture, engineering, and medical applications. Therefore, this study has been carried out due to the isolation of colorant from Arjun bark in an acidified methanolic medium after exposure to ultrasonic rays up to 60 min. Read More

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Detoxification of Aflatoxin B1 and Ochratoxin A Using Salvia farinacea and Azadirachta indica Water Extract and Application in Meat Products.

Appl Biochem Biotechnol 2021 May 24. Epub 2021 May 24.

Food Science Department, Faculty of Agriculture, Saba Basha, Alexandria University, Alexandria, Egypt.

Seventy-five samples of selected meat products, including luncheon, beef burger, sausage, basterma, and kofta, were collected from Alexandria and New Borg El-Arab cities (Egypt). The samples were subjected to mycological examination as well as for detection of aflatoxin B1 (AFB1) and ochratoxin A (OTA) residues. Besides, the study evaluated the effect of aqueous leaf extracts from mealycup sage (Salvia farinacea) and neem (Azadirachta indica), individually and in combination, on the growth of human pathogens Aspergillus parasiticus and Aspergillus flavus producing AFB1, as well as Aspergillus ochraceus and Aspergillus niger which produce OTA. Read More

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Comparison of Antimicrobial Efficacy of Natural Extracts as a Disinfectant for Removable Orthodontic Appliances: An Study.

Int J Clin Pediatr Dent 2020 Nov-Dec;13(6):640-643

Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences, Bengaluru, Karnataka, India.

Aim: The purpose of the study is to formulate a standard protocol for cleaning and disinfecting removable appliances by evaluating the antimicrobial efficacy of three natural extracts.

Materials And Methods: Fifty patients with removable orthodontic appliances were selected and divided into five groups [chlorhexidine 0.2% (positive control), extracts of , , cinnamon, and normal saline (negative control)] with 10 samples each. Read More

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Extracts of herbs and spices as feed additives mitigate ruminal methane production and improve fermentation characteristics in West African Dwarf sheep.

Trop Anim Health Prod 2021 May 9;53(2):312. Epub 2021 May 9.

Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, Edo de México, México.

The study aims to evaluate the effect of aqueous and methanolic extracts of three herbs, namely, neem (Azadirachta indica), drumstick (Moringa oleifera) and scent (Ocimum gratissimum), and three spices garlic (Allium sativum), ginger (Zingiber officinale) and onion leaflets (Allium cepa) on ruminal methane production and fermentation characteristics. The feed samples (200 mg substrates plus extracts of the selected herbs and spices) were incubated with rumen liquor taken from three mature West African dwarf ewes at 3, 6, 9, 12, 15, 18, 21 and 24 h. The results show that extracts of the selected herbs and spices increased the gas produced, from the insoluble fraction, degradability rate, volume of gas produced at time and time of most rapid change in gas produced. Read More

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The anti-cancer properties of neem () through its antioxidant activity in the liver; its pharmaceutics and toxic dosage forms; a literature review.

J Complement Integr Med 2021 May 10. Epub 2021 May 10.

Department of Physiology and Medical Physics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Objectives: The neem () have been used in herbal medicine for the treatment of multiple diseases, particularly cancer. The mechanism of anti-cancer properties of neem are far from clear. However, it is well accepted that anti-cancer effects of neem is mediated via its hepatic anti-oxidant activity. Read More

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Extract of neem (Azadirachta indica) leaf exhibits bactericidal effect against multidrug resistant pathogenic bacteria of poultry.

Vet Med Sci 2021 May 6. Epub 2021 May 6.

Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.

The aim of the study was to determine the efficacy of neem leaf extract against multidrug resistant (MDR) pathogenic bacteria. Laboratory stock culture of Pasteurella multocida, Salmonella pullorum, Salmonella gallinarum and Escherichia coli was revived. Antibiogram profiles of these bacteria were determined by disc diffusion method. Read More

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Silver nanoparticles synthesized using leaf extract of exhibit enhanced antimicrobial efficacy than the chemically synthesized nanoparticles: A comparative study.

Sci Prog 2021 Apr-Jun;104(2):368504211012159

Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

A wide variety of methods have synthesized silver nanoparticles (Ag-NPs) in the recent past; however, biological methods have attracted much attention over the traditional chemical synthesis method due to being non-hazardous and eco-friendly. Here, a detailed and systemic study was performed to compare two different synthesis routes for Ag-NPs, that is, the chemical and the biological; their possible outcomes have also been described. Ag-NPs were synthesized chemically (cAg-NPs) using a chemical reductant and biologically (bAg-NPs) by using aqueous leaf extract of (neem). Read More

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Antifungal Activity of Propyl Disulfide from Neem () in Vapor and Agar Diffusion Assays against Anthracnose Pathogens ( and ) in Mango Fruit.

Microorganisms 2021 Apr 14;9(4). Epub 2021 Apr 14.

College of Integrative Medicine, Dhurakij Pundit University, Bangkok 10210, Thailand.

Microorganisms causing anthracnose diseases have a medium to a high level of resistance to the existing fungicides. This study aimed to investigate neem plant extract (propyl disulfide, PD) as an alternative to the current fungicides against mango's anthracnose. Microorganisms were isolated from decayed mango and identified as and Next, a pathogenicity test was conducted and after fulfilling Koch's postulates, fungi were reisolated from these symptomatic fruits and we thus obtained pure cultures. Read More

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Synthesis and characterization of nanoparticles from neem leaves and banana peels: a green prospect for dye degradation in wastewater.

Ecotoxicology 2021 Apr 27. Epub 2021 Apr 27.

Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha, India.

Nanoparticles have excellent catalytic, adsorptive, and reactive properties, which led to their application for wastewater treatment. The current study focuses on silver nanoparticle synthesis using neem leaf and banana peel extract and its application as an antimicrobial and dye degrading agent for wastewater treatment. The use of these extracts led to a rapid, simple, and environment-friendly method for the biosynthesis of silver nanoparticles (AgNPs). Read More

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Neem (Azadirachta Indica A. Juss) Capsules for Prophylaxis of COVID-19 Infection: A Pilot, Double-Blind, Randomized Controlled Trial.

Altern Ther Health Med 2021 Apr 23. Epub 2021 Apr 23.

Context: SARS-CoV-2 is a global public-health concern. Interventions to prevent infection are urgently needed. The anti-inflammatory and antiviral effects of neem make it a potential agent for COVID-19 prophylaxis. Read More

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Anti-plasmodial activity of aqueous neem leaf extract mediated green synthesis-based silver nitrate nanoparticles.

Prep Biochem Biotechnol 2021 Apr 23:1-9. Epub 2021 Apr 23.

Institute of Research in Molecular Medicine, (INFORMM), Health Campus Universiti Sains Malaysia (USM), Kelantan, Malaysia.

The objective of this study is to synthesize neem-silver nitrate nanoparticles (neem-AgNPs) using aqueous extracts of A. Juss for malaria therapy. Neem leaves collected from FRIM Malaysia were authenticated and extracted using Soxhlet extraction method. Read More

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Neem Leaf ( A. Juss) Ethanolic Extract on the Liver and Kidney Function of Rats.

ScientificWorldJournal 2021 30;2021:7970424. Epub 2021 Mar 30.

Laboratory of Pathology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.

Neem ( A. Juss) is one of the tropical plants found in Indonesia that has been used to prevent and treat various diseases. This study aimed to investigate the effect of the ethanol extract of neem leaves on the concentration of aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, and creatinine in male rats. Read More

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Hematopoietic effects of Azadirachta indica methanolic extract in cyclophosphamide mediated myelosuppressed albino rat.

Pak J Pharm Sci 2020 Sep;33(5(Supplementary)):2269-2273

Imran Adrees College of Pharmacy, 3Km Daska Road, Sialkot, Pakistan.

Myelosuppression or bone marrow suppression is one of the most common side effects caused by anti-cancer drugs. Certain nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics and viruses like B19 virus can also cause bone marrow suppression resulting in serious consequences like leukopenia, anemia and thrombocytopenia. Currently, it is mainly treated by Filgrastim, use of which is not without side effects. Read More

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September 2020

Improvement and prediction of secondary metabolites production under yeast extract elicitation of Azadirachta indica cell suspension culture using response surface methodology.

AMB Express 2021 Mar 17;11(1):43. Epub 2021 Mar 17.

Department of Biotechnology, Faculty of Agriculture and Natural Resources, Imam Khomeini International University (IKIU), P. O. Box 288, 34149-16818, Qazvin, Islamic Republic of Iran.

Neem is a medicinal plant used as antimalarial, antibacterial, antiviral, insecticide, and antimicrobial drug. This study aimed to investigate and predict the effect of yeast extract and sampling time on cell growth, secondary metabolites synthesis, SQS1 and MOF1 genes expression by response surface methodology. The highest fresh and dry cell weights were 580. Read More

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Fractionated Extracts From Gnidia kraussiana (Malvales: Thymeleaceae) as Bioactive Phytochemicals for Effective Management of Callosobruchus maculatus (Coleoptera: Chrysomelidae) in Stored Vigna unguiculata (Fabales: Fabaceae) Seeds.

J Insect Sci 2021 Jan;21(1)

Phytochemistry Laboratory, Institute of Medical Research and Medicinal Plants Studies (IMPM), Yaoundé, Cameroon.

One of the most important global problems is protecting food from insect pests. The negative effects of synthetic insecticides on human health led to a resurgence of interest in botanical insecticides due to their minimal ecological side effects. Therefore, the insecticidal potential of hexane, acetone, and methanol extracts of Gnidia kraussiana Meisn roots at 1 and 5g/kg, and neem seed oil (NSO), used as standard insecticide, were evaluated. Read More

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January 2021

Efficacy of neem (Azadirachta indica) aqueous fruit extracts against Sarcoptes scabiei var. suis in grower pigs.

Trop Anim Health Prod 2021 Jan 22;53(1):135. Epub 2021 Jan 22.

Department of Animal Production and Technology, Chinhoyi University of Technology, 78 Off Harare-Chirundu Road, Private Bag, 7724, Chinhoyi, Zimbabwe.

The acaricidal activity of Azadirachta indica (neem) aqueous fruit extracts was evaluated against Sarcoptes scabiei var. suis (mange mites) in an on-farm trial using grower pigs. Aqueous neem fruit extracts of three concentrations 5%, 10%, and 25% w/v and a commercial acaricide, 12. Read More

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January 2021

Biogenic Ag Nanoparticles from Neem Extract: Their Structural Evaluation and Antimicrobial Effects against and (NII 08123).

ACS Biomater Sci Eng 2020 01 11;6(1):235-245. Epub 2019 Dec 11.

Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201002, India.

Silver nanocrystals have been successfully fabricated by the bioreduction route using the ethanolic extract of (neem) leaves as the reducing and capping agent without solvent interference. The silver nanocrystals were grown in a single-step method, without the influence of external energy or surfactants, and at room temperature. The nanoparticles were prepared from different ratios of silver ions to reducing agent molecules and were characterized by UV-vis spectroscopy and transmission electron microscopy (TEM). Read More

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January 2020

Administration of neem ( A. Juss) leaf extract decreases TNF-α and IL-6 expressions in dextran sodium sulfate-induced colitis in rats.

J Adv Vet Anim Res 2020 Dec 4;7(4):744-749. Epub 2020 Dec 4.

Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Objective: We aimed to determine the neem leaf extract's effect on Tumor Necrosis Factor-alpha (TNF-α) and Interleukin-6 (IL-6) expressions in dextran sodium sulfate (DSS)-induced colitis rats.

Materials And Methods: In the first phase of the study, colitis was induced by DSS administration in the case group and compared to the control group. In the second phase, 84 colitis rats were divided into groups I, II, and III receiving 7. Read More

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December 2020

Evaluation of the Effect of an Aqueous Extract of (Neem) Leaves and Twigs on Glycemic Control, Endothelial Dysfunction and Systemic Inflammation in Subjects with Type 2 Diabetes Mellitus - A Randomized, Double-Blind, Placebo-Controlled Clinical Study.

Diabetes Metab Syndr Obes 2020 17;13:4401-4412. Epub 2020 Nov 17.

Department of Pharmacology and Therapeutics, Nizam's Institute of Medical Sciences, Hyderabad, Telangana 500073, India.

Purpose: Neem tree () offers different bioactives ranging from pesticides to therapeutic molecules, depending on which part of the plant is used and the extraction methodology and the solvent used. This study was aimed at evaluating the safety and efficacy of a standardized aqueous extract of leaves and twigs (NEEM) on glycemic control, endothelial dysfunction, and systemic inflammation in patients with type 2 diabetes mellitus (T2DM).

Methods: In this randomized, double-blind, placebo-controlled clinical study (RCT), 80 T2DM subjects, who have already been on standard metformin therapy, received either 125 mg, 250 mg, 500 mg of NEEM or placebo twice daily for 12 weeks. Read More

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November 2020

Enhanced Biosynthesis Synthesis of Copper Oxide Nanoparticles (CuO-NPs) for their Antifungal Activity Toxicity against Major Phyto-Pathogens of Apple Orchards.

Pharm Res 2020 Nov 19;37(12):246. Epub 2020 Nov 19.

Department of Biotechnology, Vels Institute of Science Technology & Advanced Studies (VISTAS), Pallavarm, Chennai, Tamil Nadu (TN), 600117, India.

Purpose: The present study made an attempt to develop copper nanoparticles (Cu-NP) with antifungal property using green synthesis method. Copper oxide nanoparticles (CuO-NPs) botanically synthesized using Neem leaf extract (Azadirachta indica A. Juss) were characterized by using different techniques like; UV-visible spectrophotometry, FTIR, XRD, SEM and TEM. Read More

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November 2020

Evaluation of the Role of Propolis and a New Herbal Ointment in Promoting Healing of Traumatic Oral Ulcers: An Animal Experimental Study.

Contemp Clin Dent 2020 Apr-Jun;11(2):121-125. Epub 2020 Aug 7.

Department of Pharmacology, Jawaharlal Nehru Medical College. DMIMS DU, Sawangi Meghe, Wardha, India.

Most of the currently used medications for the treatment of oral ulcers focus primarily on providing symptomatic relief and preventing secondary infections. Not much attention has been paid in the past on agents that can promote healing of these lesions. In the current study, we have tested and compared the efficacy of such wound healing promoting agents i. Read More

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Antibacterial property of , , and against oral microbes.

J Conserv Dent 2019 Nov-Dec;22(6):602-606. Epub 2020 Aug 20.

Department of Oral Pathology, Regional Dental College, Guwahati, Assam, India.

Context: Plant extracts are used in folklore medicine from time immemorial to treat different oral diseases. Chemical constituents extracted from these natural resources are gifted with huge opportunities.

Aim: The aim of this study is to assess the antibacterial property of (Neem), (Tulsi), and (Pochotia) against oral microorganisms. Read More

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Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID-19 infection to improve patient outcomes and to protect healthcare workers treating them.

Cochrane Database Syst Rev 2020 09 16;9:CD013627. Epub 2020 Sep 16.

Cochrane Oral Health, Division of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

Background: COVID-19 infection poses a serious risk to patients and - due to its contagious nature - to those healthcare workers (HCWs) treating them. If the mouth and nose of patients with infection are irrigated with antimicrobial solutions, this may help the patients by killing any coronavirus present at those sites. It may also reduce the risk of the active infection being passed to HCWs through droplet transmission or direct contact. Read More

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September 2020

A quadruple blind, randomised controlled trial of gargling agents in reducing intraoral viral load among hospitalised COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial.

Trials 2020 Sep 14;21(1):785. Epub 2020 Sep 14.

Department of Surgery, Aga Khan University, Karachi, 74800, Pakistan.

Objectives: 1- To compare the effectiveness of 1% Hydrogen peroxide, 0.2% Povidone-Iodine, 2% hypertonic saline and a novel solution Neem extract (Azardirachta indica) in reducing intra-oral viral load in COVID-19 positive patients. 2- To determine the salivary cytokine profiles of IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ and IL- 17 among COVID-19 patients subjected to 1% Hydrogen peroxide, 0. Read More

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September 2020

Angiogenic and anti-inflammatory properties of azadirachtin A improve random skin flap survival in rats.

Exp Biol Med (Maywood) 2020 12 31;245(18):1672-1682. Epub 2020 Aug 31.

Department of Hand Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second Clinical College of Wenzhou Medical University, Wenzhou 325027, China.

Random skin flaps are widely used to repair tissue defects. However, the distal flap regions are prone to ischemic necrosis, limiting clinical applications. Azadirachtin A, a fruit extract from the neem, improves tissue blood supply and metabolism, reduces cell swelling, promotes tissue healing, and prevents venous thrombosis. Read More

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December 2020

Common garlic (Allium sativum L.) has potent Anti-Bacillus anthracis activity.

J Ethnopharmacol 2021 Jan 24;264:113230. Epub 2020 Aug 24.

Department of Microbial Biotechnology, Panjab University, Chandigarh, 160014, India; Centre of Experimental Medicine and Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India. Electronic address:

Ethnopharmacological Relevance: Gastrointestinal anthrax, a disease caused by Bacillus anthracis, remains an important but relatively neglected endemic disease of animals and humans in remote areas of the Indian subcontinent and some parts of Africa. Its initial symptoms include diarrhea and stomachache. In the current study, several common plants indicated for diarrhea, dysentery, stomachache or as stomachic as per traditional knowledge in the Indian subcontinent, i. Read More

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January 2021

Dietary supplementation of Neem () leaf extracts improved growth performance and reduced production cost in broilers.

Vet World 2020 Jun 11;13(6):1050-1055. Epub 2020 Jun 11.

Department of Animal Science, School of Environmental and Rural Science, University of New England, Australia.

Background And Aim: Global trend to remove the antibiotic growth promoter (AGP) from animals contributes to the exploration of successful measures to sustain production and reduces the intestinal diseases in the post-AGP era. Plant extracts, therefore, have been used to improve performance and intestinal health. Here, we conducted a study to evaluate the effects of neem () leaf extracts (NLE) as alternatives to AGPs in broiler chickens. Read More

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