1,285 results match your criteria needle passes


Adequacy of small biopsy and cytology specimens for comprehensive genomic profiling of patients with non-small-cell lung cancer to determine eligibility for immune checkpoint inhibitor and targeted therapy.

J Clin Pathol 2021 May 5. Epub 2021 May 5.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Aims: In advanced-stage non-small-cell lung cancer (NSCLC), incomplete genotyping for guideline-recommended genomic biomarkers poses a significant challenge to making informed and timely clinical decisions. We report our institution's experience in assessing the adequacy of small specimens for comprehensive genomic profiling for guideline-recommended lung cancer biomarker testing.

Methods: We performed a retrospective evaluation of all image-guided procedures for NSCLC performed in our institution between October 2016 and July 2018, including core needle biopsy (CNB) and fine-needle aspiration (FNA) in patients who had undergone genomic profiling for lung cancer. Read More

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Intermittent endoscopic ultrasound guided fine-needle aspiration for the diagnosis of solid pancreatic lesions. Pilot study.

Rev Esp Enferm Dig 2021 May 5. Epub 2021 May 5.

Aparato Digestivo, Hospital Universitario de La Princesa, ESPAÑA.

Background and purpose of the study: endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) is the method of choice for sampling pancreatic solid lesions. However, there is significant heterogeneity in terms of the technique used. Intermittent aspiration has not been evaluated in pancreatic solid lesions and could improve the diagnostic performance. Read More

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Deformation of Needle Tips during Facial Soft Tissue Filler Injections: An Electron-Microscopic Study.

Aesthet Surg J 2021 May 4. Epub 2021 May 4.

Department of Clinical Anatomy, Mayo Clinic College of Medicine and Science, Rochester, MN.

Background: Injectable soft tissue fillers are used on a global scale for a variety of aesthetic indications. Despite their widespread use, there is a dearth of information regarding the potential repeated injections into tissue have to cause needle deformation. Repeated injections with the same needle result in an increase in force used by the injector to achieve dermal penetration, potentially resulting in decreased precision and increased patient discomfort. Read More

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Connect your needle to a smartphone to increase EUS FNA sample quality and diagnostic accuracy of solid pancreatic masses: a randomized trial.

Endoscopy 2021 May 3. Epub 2021 May 3.

Gastroenterology and Hepatology, Carol Davila University of Medicine and Pharmacy, Bucuresti, Romania.

Background And Study Aims: EUS FNA is recommended for diagnosis of solid pancreatic masses. We aimed to evaluate if a high needle movement acceleration value during puncture increases diagnostic accuracy.

Patients And Methods: EUS FNA needle acceleration was measured using a PocketLab accelerometer connected by Bluetooth to a smartphone. Read More

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A Prospective Multicenter Study of EUS-guided Fine Needle Biopsy Using a 22-gauge Franseen Needle for Pancreatic Solid Lesions.

J Gastroenterol Hepatol 2021 May 3. Epub 2021 May 3.

Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.

Background: While encouraging data of EUS-guided fine-needle biopsy (EUS-FNB) using a 22-gauge Franseen needle have been reported, a large scale data of per pass and quantitative analyses are still lacking.

Methods: This was a multicenter prospective study of EUS-FNB using the 22-gauge Franseen needle for a pancreatic solid lesion. Cytological and histological analyses per pass were evaluated and semi-quantitative analyses were performed on core tissue (1-4) and blood contamination (1-3). Read More

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Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy Device for Lymphadenopathy.

Gastroenterol Res Pract 2021 15;2021:6640862. Epub 2021 Apr 15.

Department of Gastroenterology, Saitama Medical University International Medical Center, Japan.

Background: Accurate diagnosis of benign and malignant lymphadenopathy is important for determining the appropriate treatment and prognosis. This study evaluated the diagnostic accuracy and usefulness of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) with a conventional needle compared to endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) with a Franseen needle for diagnosing lymphadenopathy.

Methods: Patients who underwent EUS-FNA or EUS-FNB for mediastinal or abdominal lymphadenopathy between July 2013 and August 2020 were enrolled in the study. Read More

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Real-time ultrasound-guided low thoracic epidural catheter placement: technical consideration and fluoroscopic evaluation.

Reg Anesth Pain Med 2021 Apr 23. Epub 2021 Apr 23.

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea (the Republic of).

Background And Objective: Thoracic epidural analgesia can significantly reduce acute postoperative pain. However, thoracic epidural catheter placement is challenging. Although real-time ultrasound (US)-guided thoracic epidural catheter placement has been recently introduced, data regarding the accuracy and technical description are limited. Read More

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Syringe-Free, Long-Axis in-Plane Versus Short-Axis Classic out-of-Plane Approach for Ultrasound-Guided Internal Jugular Vein Catheter Placement in Critically Ill Children: A Prospective Randomized Study.

J Cardiothorac Vasc Anesth 2021 Mar 26. Epub 2021 Mar 26.

Clinical Research, Development and Design Application and Research Center, Ataturk University School of Medicine, Erzurum, Turkey; Department of Anesthesiology and Reanimation, Ataturk University School of Medicine, Erzurum, Turkey.

Objective: Although pediatric central venous catheterization is performed using ultrasound guidance, it is still a challenge. This study aimed to investigate the efficacy of the syringe-free, long-axis in-plane approach and compared the short-axis classic out-of-plane approach for ultrasound-guided central venous catheter placement in critically ill pediatric patients.

Design: Prospective randomized study. Read More

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Macroscopic on-site evaluation after EUS-guided fine needle biopsy may replace rapid on-site evaluation.

Endosc Ultrasound 2021 Mar-Apr;10(2):111-115

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

Background And Objectives: Rapid on-site cytologic evaluation (ROSE) increases the diagnostic yield of EUS-FNA. However, ROSE requires the presence of a cytopathologist and additional cost and time for slide staining and interpretation. Macroscopic on-site examination (MOSE) was recently introduced as an alternative to ROSE and showed high accuracy for the use in pathologic diagnosis. Read More

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Ultrasound-Guided Omental Biopsy: Diagnostic Yield and Association with CT Features Based on a Single-Institution 18-Year Series.

AJR Am J Roentgenol 2021 Apr 14. Epub 2021 Apr 14.

Department of Radiology, University of Wisconsin School of Medicine and Public Health.

The greater omentum can serve as a useful target for percutaneous biopsy; in clinical practice, CT is commonly used for biopsy guidance. To evaluate the diagnostic yield of percutaneous ultrasound (US)-guided omental biopsy and to explore the association of diagnostic yield with pre-biopsy diagnostic CT findings. This retrospective study included 163 patients (mean age, 65±12 years; 120 women, 43 men; mean BMI, 28. Read More

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Propensity-score-matching analysis to compare efficacy and safety between 16-gauge and 18-gauge needle in ultrasound-guided biopsy for peripheral pulmonary lesions.

BMC Cancer 2021 Apr 9;21(1):390. Epub 2021 Apr 9.

Department of Medical Ultrasonics, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou, 510515, Guangdong, China.

Background: Definitive diagnosis of peripheral pulmonary lesions (PPLs) depends on the histological analysis of the pleural biopsy sample. Ultrasound (US)-guided sampling is now standard practice in the clinical setting. However, determining a suitable needle size and sampling times to improve the efficacy and safety of the biopsy remains challenging. Read More

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A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions.

Gastroenterol Res Pract 2021 22;2021:4913107. Epub 2021 Mar 22.

Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.

Methods: Twenty-six patients with UGI-SELs indicated for EUS-FNA were randomly assigned to the dry-first arm using the dry technique for the first two passes or the wet-first arm using the wet technique for the first two passes using a cross-over design with a ratio of 1 : 1. The primary endpoint was the cellularity score of the EUS-FNA specimens rated on a 4-point scale (0-3). The secondary endpoints were the factors influencing cellularity in each suction technique. Read More

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The Role of Endoscopic Ultrasound in Pancreatic Cancer Staging in the Era of Neoadjuvant Therapy and Personalised Medicine.

GE Port J Gastroenterol 2021 Feb 7;28(2):111-120. Epub 2020 Sep 7.

Department of Gastroenterology and Digestive Endoscopy, Champalimaud Foundation, Lisbon, Portugal.

Precise staging of pancreatic cancer is crucial for treatment choice. In clinical practice, this includes the TNM staging and determination of tumour resectability, based on a multimodality imaging workup. International guidelines recommend multi-detector computed tomography (CT), with a dedicated pancreatic protocol, as the first-line tool for TNM staging and evaluation of tumour-vessel relationships. Read More

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February 2021

Does ProCore fine needle biopsy really improve the clinical outcome of endoscopic ultrasound-guided sampling of pancreatic masses?

Dig Dis 2021 Mar 29. Epub 2021 Mar 29.

Introduction: Fine Needle Biopsy (FNB) has been suggested to provide better histological samples as compared to endoscopic ultrasound fine needle aspiration (EUS-FNA). However, studies comparing EUS-FNA and EUS-FNB for pancreatic lesions reported contrasting results. The aim of this study was to compare the clinical performance of EUS-FNA versus EUS-FNB with ProCore needle for the investigation of pancreatic lesions. Read More

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Single pass, 1 needle actuation versus single pass 3 actuation technique for EUS-guided liver biopsy: a randomized prospective trial (with video).

Gastrointest Endosc 2021 Mar 23. Epub 2021 Mar 23.

Geisinger Medical Center. 100 N. Academy Ave, 21-11 Danville, PA 17822. Electronic address:

Background And Aims: Several reports have validated endoscopic ultrasound-guided liver biopsy (EUS-LB) as safe and effective. Nineteen-gauge EUS aspiration (fine-needle aspiration [FNA]) or core (fine-needle biopsy [FNB]) needles are used, but different needle techniques can yield variable outcomes. Some data shows 1 pass (single liver puncture) with 1 actuation (one to-and-fro needle movement) may be enough to obtain a satisfactory specimen. Read More

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Clinical and Technical Guideline for Endoscopic Ultrasound (EUS)- Guided Tissue Acquisition of Pancreatic Solid Tumor: Korean Society of Gastrointestinal Endoscopy (KSGE).

Gut Liver 2021 Mar 26. Epub 2021 Mar 26.

Division of Gastroenterology, Department of Internal Medicine, Cha University College of Medicine, Seongnam, Korea.

Endoscopic ultrasound (EUS)-guided tissue acquisition of pancreatic solid tumor requires a strict recommendation for its proper use in clinical practice because of its technical difficulty and invasiveness. The Korean Society of Gastrointestinal Endoscopy (KSGE) appointed a task force to draft clinical practice guidelines for EUS-guided tissue acquisition of pancreatic solid tumor. The strength of recommendation and the level of evidence for each statement were graded according to the Minds Handbook for Clinical Practice Guideline Development 2014. Read More

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Clinical and Technical Guideline for Endoscopic Ultrasound (EUS)-Guided Tissue Acquisition of Pancreatic Solid Tumor: Korean Society of Gastrointestinal Endoscopy (KSGE).

Clin Endosc 2021 Mar 24;54(2):161-181. Epub 2021 Mar 24.

Division of Gastroenterology, Department of Internal Medicine, Cha University College of Medicine, Seongnam, Korea.

Endoscopic ultrasound (EUS)-guided tissue acquisition of pancreatic solid tumor requires a strict recommendation for its proper use in clinical practice because of its technical difficulty and invasiveness. The Korean Society of Gastrointestinal Endoscopy (KSGE) appointed a Task Force to draft clinical practice guidelines for EUS-guided tissue acquisition of pancreatic solid tumor. The strength of recommendation and the level of evidence for each statement were graded according to the Minds Handbook for Clinical Practice Guideline Development 2014. Read More

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Histological alterations following fine-needle aspiration for parathyroid adenoma: Incidence and diagnostic problems.

Pathol Int 2021 Mar 19. Epub 2021 Mar 19.

Department of Surgery, Kuma Hospital, Kobe, Hyogo, Japan.

This study aimed to clarify the histological alterations following fine-needle aspiration for parathyroid adenoma and discuss the occurrence of diagnostic problems. Among the 392 patients with parathyroid adenoma who underwent resection, fine-needle aspiration was performed for 21 (5.1%) parathyroid adenoma nodules. Read More

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Endoscopic ultrasound-guided sampling of gastrointestinal subepithelial lesions: just wet it.

Eur J Gastroenterol Hepatol 2021 Mar 12. Epub 2021 Mar 12.

Gastroenterology Department, Portuguese Oncology Institute Departamento de Medicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS) Surgery and Physiology Department, Faculty of Medicine of the University of Porto, Porto, Portugal.

Introduction: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the main method for acquisition of tissue from gastrointestinal subepithelial lesions (SELs). Despite the development of new needles, diagnostic yield remains low. A new method of aspiration has been described, where the needle is filled with saline [wet-suction technique (WST)], with promising results in pancreatic lesions. Read More

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Standardization of thyroid fine needle aspiration procedure and outcomes within an endocrine surgery department.

Gland Surg 2021 Feb;10(2):567-573

Department of Endocrine Surgery, Cleveland Clinic, Cleveland, OH, USA.

Background: Fine needle aspiration (FNA) biopsy is an essential procedure for thyroid nodules. Although, the efficacy of surgeon-performed thyroid FNA biopsies has been demonstrated in the literature, there are insufficient data regarding how to establish an efficient program with a low insufficiency rate within a group practice.

Methods: An endocrine surgery thyroid FNA biopsy program was established in 2000 by one surgeon, with training of additional partners during fellowship and upon recruitment. Read More

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February 2021

Performance of cytology, acid-fast bacilli smear, gene Xpert and mycobacterial cultures in endobronchial ultrasound-transbronchial needle aspiration aspirate in diagnosing mediastinal tuberculous lymphadenitis.

Lung India 2021 Mar-Apr;38(2):122-127

Department of Pulmonary Medicine, Fortis Flt. Lt. Rajan Dhall Hospital, New Delhi, India.

Background: Diagnosis of isolated mediastinal tuberculosis (TB) can be challenging. Endobronchial ultrasound (EBUS) increases the diagnostic yield by direct sonographic visualization of mediastinal and hilar lymph nodes. With the advent of molecular techniques such as Gene Xpert, their addition to the cytology and cultures increases the diagnostic yield and detection of rifampicin resistance (RR) which helps change the effective therapeutic regimen immediately. Read More

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Use of suction during endoscopic ultrasound-guided fine needle biopsy of solid pancreatic lesions with a Franseen-tip needle: a pilot comparative trial.

Endosc Int Open 2021 Mar 19;9(3):E401-E408. Epub 2021 Feb 19.

Gastroenterology Department, Centro Hospitalar e Universitário São João, Porto, Portugal.

 The utility of suction during endoscopic ultrasound (EUS) fine-needle biopsy (FNB) using Franseen-tip needle remains unclear and has not been evaluated in randomized trials. We designed a randomized crossover trial to compare the diagnostic yield during EUS-FNB using a 22G Franseen-tip needle, with and without standard suction. Consecutive patients undergoing EUS-guided sampling of solid pancreatic lesions were recruited. Read More

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Ultrasound-guided percutaneous needle tenotomy (PNT) alone versus PNT plus platelet-rich plasma injection for the treatment of chronic tendinosis: A randomized controlled trial.

PM R 2021 Feb 28. Epub 2021 Feb 28.

Department of Physiatry, Hospital for Special Surgery, New York, New York, USA.

Background: Tendinosis is a chronic degenerative condition. Current research suggests both percutaneous needle tenotomy (PNT) and leukocyte-rich platelet-rich plasma (LR-PRP) may be effective treatments for chronic tendinosis, but no studies have assessed the effectiveness of PNT alone versus PNT with intratendinous LR-PRP for multiple tendon types in a single study.

Objective: To assess the efficacy of PNT versus PNT + LR-PRP to treat chronic tendinosis. Read More

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February 2021

Comparison of contrast-enhanced ultrasound versus conventional ultrasound-guided percutaneous nephrolithotomy in patients with nondilated collecting system: a randomized controlled trial.

Eur Radiol 2021 Feb 26. Epub 2021 Feb 26.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Objective: To compare the safety, effectiveness, and feasibility of contrast-enhanced ultrasound (CEUS) versus conventional ultrasound-guided percutaneous nephrolithotomy (PCNL) in patients with nondilated collecting system.

Methods: Between July 2018 and July 2020, 160 kidney stone patients with nondilated collecting system planned for PCNL were randomly assigned into two groups, CEUS with retrograde ureteral contrast injection and conventional ultrasound with retrograde ureteral normal saline injection. Patient's demographics, the success rate of puncture, success rate of a single-needle puncture, number of punctures, puncture time, perioperative outcomes, stone-free rate, and incidence of complications were compared. Read More

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February 2021

Percutaneous Image-Guided Core Needle Biopsy of Neuroendocrine Tumors: How Common Is Intraprocedural Carcinoid Crisis?

J Vasc Interv Radiol 2021 05 16;32(5):745-751. Epub 2021 Feb 16.

Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905.

Purpose: To retrospectively evaluate the incidence of carcinoid crisis, other complications, and physiologic disturbances during percutaneous image-guided core needle biopsy of neuroendocrine tumors (NETs) in the lung and the liver.

Materials And Methods: Between January 2010 and January 2020, 106 computed tomography (CT) or ultrasound (US)-guided core needle biopsies of lung and liver NETs were performed in 95 consecutive adult patients. The mean age was 64 ± 13 years, and 48% were female. Read More

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Extraplexus versus intraplexus ultrasound-guided interscalene brachial plexus block for ambulatory arthroscopic shoulder surgery: A randomized controlled trial.

PLoS One 2021 18;16(2):e0246792. Epub 2021 Feb 18.

Department of Anesthesia and Perioperative Care, University of California, San Francisco, California, United States of America.

Background: This randomized study compared the efficacy and safety of extraplexus and intraplexus injection of local anesthetic for interscalene brachial plexus block.

Methods: 208 ASA I-II patients scheduled for elective shoulder arthroscopy under general anesthesia and ultrasound-guided interscalene brachial plexus block were randomly allocated to receive an injection of 25mL ropivacaine 0.5% either between C5-C6 nerve roots (intraplexus), or anterior and posterior to the brachial plexus into the plane between the perineural sheath and scalene muscles (extraplexus). Read More

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February 2021

CT fluoroscopy-guided percutaneous intervertebral drain insertion for cervical pyogenic spondylodiscitis.

Diagn Interv Radiol 2021 Mar;27(2):269-271

Department of Radiology, Tokai University Hachioji Hospital, Tokai University School of Medicine, Hachioji, Tokyo, Japan.

A 79-year-old man was admitted to our hospital with C6-C7 pyogenic spondylodiscitis with an epidural abscess. Since the cervical intervertebral space is narrower than the thoracolumbar intervertebral space, drain insertion into the cervical intervertebral space requires a more accurate procedure. Moreover, the specific anatomy of cervical vertebrae, which includes the transverse foramen through which the vertebral artery passes and the uncinate process on the side edges of the top surface of the bodies, makes it impossible to perform computed tomography (CT)-guided percutaneous intervertebral drain insertion through the posterolateral approach. Read More

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Optimal number of needle passes during EUS-guided fine-needle biopsy of solid pancreatic lesions with 22G ProCore needles and different suction techniques: A randomized controlled trial.

Endosc Ultrasound 2021 Jan-Feb;10(1):62-70

Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China.

Background And Objectives: The sensitivity of EUS-guided fine-needle biopsy (EUS-FNB) varies considerably. The optimal number of passes through a solid pancreatic lesion with a 22G FNB needle during EUS-FNB is controversial. This prospective randomized controlled study aimed to determine the optimal number of needle passes during EUS-FNB of solid pancreatic lesions, with 22G FNB needles and different sampling techniques. Read More

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February 2021

Accuracy of Subclassification and Grading of Renal Tumors on Fine Needle Aspiration Cytology Alone.

Acta Cytol 2021 3;65(2):140-149. Epub 2021 Feb 3.

Department of Pathology, The University of Chicago Hospitals, Chicago, Illinois, USA.

Background: Fine needle aspiration (FNA) of renal masses can distinguish between benign and malignant neoplasms in 73-94% of cases. Previous studies suggested the correct subclassification of renal cell carcinomas (RCCs) by cytomorphology can be achieved in up to 80% of cases. However, as RCCs become increasingly subclassified by molecular signatures, correct subclassification based on cytology alone is increasingly difficult. Read More

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Endoscopic ultrasound (EUS)-guided fine needle biopsy alone vs. EUS-guided fine needle aspiration with rapid onsite evaluation in pancreatic lesions: a multicenter randomized trial.

Endoscopy 2021 Jan 27. Epub 2021 Jan 27.

Division of Gastroenterology and Hepatology, Royal Alexandra Hospital, University of Alberta, Edmonton, Alberta, Canada.

Background:  Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the standard in the diagnosis of solid pancreatic lesions, in particular when combined with rapid onsite evaluation of cytopathology (ROSE). More recently, a fork-tip needle for core biopsy (FNB) has been shown to be associated with excellent diagnostic yield. EUS-FNB alone has however not been compared with EUS-FNA + ROSE in a large clinical trial. Read More

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January 2021