15,883 results match your criteria natural assisted

Extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: Current status and trends.

Ultrason Sonochem 2021 May 4;74:105584. Epub 2021 May 4.

Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), University of Campinas, UNICAMP, 13484-350 Limeira, SP, Brazil. Electronic address:

Natural products are a source of a wide range of chemical compounds, from pigments to bioactive compounds, which can be extracted and used in different applications. Due to consumer awareness, the interest in natural compounds significantly increased in the last decades, prompting the search for more efficient and environmentally friendly extraction techniques and methods. Pressurized liquids and fluids (sub and supercritical) are being explored to extract natural compounds within the green process concept. Read More

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Determination of imidacloprid and acetamiprid in bottled juice by a new DLLME-HPLC.

Environ Sci Pollut Res Int 2021 May 10. Epub 2021 May 10.

College of Chemical Engineering, Xinjiang Agriculture University, No. 311, Agriculture University East Street, Urumqi, 830052, China.

A new kind of surfactant-emulsified vortex-assisted dispersive liquid-liquid microextraction method (SE-VA-DLLME) using benzyldimethyldodecylammonium chloride (BDDAC) as emulsifier and disperser has been developed for the determination of imidacloprid and acetamiprid in bottled grenadine and black currant juice samples prior to high-performance liquid chromatography-diode array detection. For grenadine juice and black currant juice, LODs were 0.78 and 0. Read More

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Current Strategies in the Treatment of Intracranial Large and Giant Aneurysms.

Acta Neurochir Suppl 2021 ;132:19-26

Department of Neurosurgery, Kepler University Hospital, Linz, Austria.

Introduction: Very large and giant aneurysms are among the most challenging cerebrovascular pathologies in neurosurgery.

Methods: The aim of this paper is to review the current literature on the management of very large and giant aneurysms and to describe representative cases illustrating possible treatment strategies.

Results: In view of the poor natural history, active management using multiprofessional individualized approaches is required to achieve aneurysm occlusion, relief of mass effect, and obliteration of the embolic source. Read More

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January 2021

Development of genic SSR marker resources from RNA-seq data in Camellia japonica and their application in the genus Camellia.

Sci Rep 2021 May 10;11(1):9919. Epub 2021 May 10.

Forestry and Fruit Tree Research Institute, Wuhan Academy of Agricultural Sciences, Wuhan, 430075, China.

Camellia is a genus of flowering plants in the family Theaceae, and several species in this genus have economic importance. Although a great deal of molecular makers has been developed for molecular assisted breeding in genus Camellia in the past decade, the number of simple sequence repeats (SSRs) publicly available for plants in this genus is insufficient. In this study, a total of 28,854 potential SSRs were identified with a frequency of 4. Read More

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Comparison of the Method of Endometrial Preparation Prior to Frozen-Thawed Embryo Transfer: a Retrospective Cohort Study from 9733 Cycles.

Reprod Sci 2021 May 10. Epub 2021 May 10.

Department of Gynecology, The First Affiliated Hospital of Xi'an Medical College, Xi'an City, Shaanxi Province, China.

Our objective was to compare the effectiveness of natural cycles (NC), modified natural cycle (mNC), and artificial cycles (AC) in women undergoing frozen-thawed embryo transfer (FET) after in vitro fertilization (IVF). This is a retrospective cohort study analyzing 9733 women undergoing the first cycle of FET over a 3-year period (June 2014-December 2017) at Northwest Women's and Children's Hospital after IVF-ICSI cycles. The type of endometrial preparation was determined by the treating physician's preference, based on patients' characteristics. Read More

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Fine mapping of hybrid necrosis gene Ne1 in common wheat (Triticum aestivum L.).

Theor Appl Genet 2021 May 10. Epub 2021 May 10.

The State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, the Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, 100101, China.

Key Message: Hybrid necrosis gene Ne1 was delimited into an approximate 4.06 Mb region on chromosome arm 5BL and an InDel marker that co-segregated with Ne1 alleles was developed. Hybrid necrosis in wheat, characterized by progressive chlorosis and necrosis of plant leaves, tillers or whole plants in certain hybrids, is caused by complementary genes Ne1 and Ne2 located on chromosome arms 5BL and 2BS, respectively. Read More

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Recent Advances in Living Cationic Polymerization with Emerging Initiation/Controlling Systems.

Macromol Rapid Commun 2021 May 10:e2100148. Epub 2021 May 10.

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200433, P. R. China.

While the conventional living cationic polymerization (LCP) provided opportunities to synthesizing well-defined polymers with predetermined molecular weights, desirable chemical structures and narrow dispersity, it is still important to continuously innovate new synthetic methods to meet the increasing requirements in advanced material engineering. Consequently, a variety of novel initiation/controlling systems have be demonstrated recently, which have enabled LCP with spatiotemporal control, broadened scopes of monomers and terminals, more user-friendly operations and reaction conditions, as well as improved thermomechanical properties for obtained polymers. In this work, recent advances in LCP is summarized with emerging initiation/controlling systems, including chemical-initiated/controlled cationic reversible addition-fragmentation chain transfer (RAFT) polymerization, photoinitiated/controlled LCP, electrochemical-controlled LCP, thionyl/selenium halide-initiated LCP, organic acid-assisted LCP, and stereoselective LCP. Read More

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Technicization of "Birth" and "Mothering": Bioethical Debates from Feminist Perspectives.

Zairu Nisha

Asian Bioeth Rev 2021 Jun 8;13(2):133-148. Epub 2021 Mar 8.

Philosophy Department, Ramanujan College, University of Delhi, Delhi, India.

Birthing is a natural phenomenon. However, in the era of modernisation, it has dramatically changed and transformed into a technological affair. Some feminists claim that advances in medicine and assisted reproductive technologies (ARTs) have opened up numerous opportunities and choices for women to free themselves from their destined role of maternity by separating sex from reproduction. Read More

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Isolation and HPLC assisted quantification of two iridoid glycoside compounds and molecular DNA fingerprinting in critically endangered medicinal Royle ex Benth: implications for conservation.

Physiol Mol Biol Plants 2021 Apr 26;27(4):727-746. Epub 2021 Mar 26.

Department of Botany, University of Delhi, 110007 New Delhi, Delhi India.

is a medicinally important, high altitude perennial herb, endemic to the Himalayas. It possesses strong hepato-protective bioactivity that is contributed by two iridoid picroside compounds viz Picroside-I (P-I) and Picroside-II (P-II). Commercially, many based hepato-stimulatory Ayurvedic drug brands that use different proportions of P-I and P-II are available in the market. Read More

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Changes in anti-müllerian hormone after ultrasound guided aspiration and ethanol sclerotic therapy of ovarian cyst.

Taiwan J Obstet Gynecol 2021 May;60(3):509-512

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, No 199 Dunhua N Rd, Songshan District, Taipei, 105, Taiwan. Electronic address:

Objective: To evaluate the effect of transvaginal ultrasound-guided aspiration and ethanol sclerotherapy on anti-müllerian hormone (AMH) in patients with ovarian endometriomas.

Setting: Teaching hospital affiliated with Chang Gung University, Taipei.

Material And Methods: We retrospectively reviewed 124 patients, with ovarian endometriomas who underwent transvaginal aspiration and sclerotherapy of endometrioma(s) at a tertiary medical center, Chang Gung Memorial Hospital, Taipei, Taiwan. Read More

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Comparison of the effect of extraction methods on the quality of green coffee oil from Arabica coffee beans: Lipid yield, fatty acid composition, bioactive components, and antioxidant activity.

Ultrason Sonochem 2021 Apr 28;74:105578. Epub 2021 Apr 28.

Spice and Beverage Research Institute, Chinese Academy of Tropical Agricultural Sciences, Wanning, Hainan 571533, China; Key Laboratory of Processing Suitability and Quality Control of the Special Tropical Crops of Hainan Province, Wanning, Hainan 571533, China; National Center of Important Tropical Crops Engineering and Technology Research, Wanning, Hainan 571533, China.

In this study, ultrasonic/microwave-assisted extraction (UMAE), microwave-assisted extraction (UAE), ultrasound-assisted extraction (UAE), and pressurized liquid extraction (PLE) were applied to extract green coffee oil (GCO), and the physicochemical indexes, fatty acids, tocopherols, diterpenes, and total phenols as well as antioxidant activity of GCO were investigated and compared. The results indicated that the extraction yield of UMAE was the highest (10.58 ± 0. Read More

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A synthetic galectin mimic.

Angew Chem Int Ed Engl 2021 May 8. Epub 2021 May 8.

University of Amsterdam Faculty of Science: Universiteit van Amsterdam Faculteit der Natuurwetenschappen Wiskunde en Informatica, van 't Hoff Institute for Molecular Sciences, NETHERLANDS.

Galectins are a galactoside specific subclass of carbohydrate binding proteins (lectins) involved in various cellular activities, certain cancers, infections, inflammations and many other biological processes. The molecular basis for the selectivity of galectins is well-documented and revolves around appropriate interaction complementarity: an aromatic residue for C-H···π interactions and polar residues for (charge assisted) hydrogen bonds with the axial hydroxyl group of a galactoside. Despite this knowledge, no synthetic mimics are currently available. Read More

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Fate processes of Parabens, Triclocarban and Triclosan during wastewater treatment: assessment via field measurements and model simulations.

Environ Sci Pollut Res Int 2021 May 8. Epub 2021 May 8.

International Joint Research Center for Persistent Toxic Substances (IJRC-PTS), State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, 150090, China.

The high levels of parabens (including methyl-, ethyl- and propyl congeners), triclocarban (TCC) and triclosan (TCS) used every year in China might be a problem to the typical wastewater treatment plant (WWTP). This study addresses measurements of parabens, TCC and TCS Northern China WWTP and a modelling assessment on the occurrence, fate and removal pathways in WWTP. Per-capita emissions of the three parabens, TCC and TCS to the WWTP were estimated as 0. Read More

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Preparation of new hydrophobic deep eutectic solvents and their application in dispersive liquid-liquid microextraction of Sudan dyes from food samples.

Anal Bioanal Chem 2021 May 8. Epub 2021 May 8.

Department of Chemical Science & Technology, Kunming University, Kunming, 650214, Yuannan, China.

In this work, a new generation of hydrophobic deep eutectic solvents (DESs) was prepared using eugenol (as hydrogen bond donor) and benzyltriethylammonium bromide, benzyltributylammonium bromide, benzyltriethylammonium chloride and benzyltributylammonium chloride (as hydrogen bond acceptor) in different molar ratios. These DESs were applied to vortex-assisted dispersive liquid-liquid microextraction of Sudan dyes from food samples, followed by high-performance liquid chromatographic determination. The influencing parameters, including the type of DES, amount of DES, extraction time, solution pH and salt addition, were investigated and optimized. Read More

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Reproductive agency, assisted reproductive technology & obstetric violence.

Ana Bravo-Moreno

Health Care Women Int 2021 May 7:1-21. Epub 2021 May 7.

Thomas Coram Research Unit, University College London, London, UK.

In this article, I draw on ethnographic research I conducted in the UK and Spain. I analyse the experiences of women who chose to become mothers with the assistance of reproductive technologies (ART). All the women intended to have a natural birth in hospital and they reported that hospitals categorised their pregnancies as high-risk on the basis of their age (35-47 years) and the use of ART. Read More

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Androgen-induced gut dysbiosis disrupts glucolipid metabolism and endocrinal functions in polycystic ovary syndrome.

Microbiome 2021 May 6;9(1):101. Epub 2021 May 6.

Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China.

Background: The characteristics of polycystic ovary syndrome (PCOS), a common reproductive endocrinal disorder, are high incidence, complicated aetiology and poor therapeutic effects. PCOS patients frequently exhibit gut dysbiosis; however, its roles in the regulation of metabolic and endocrinal balances in PCOS pathophysiology are not clear.

Results: In this study, gut dysbiosis was reproduced in dehydroepiandrosterone (DHEA)-induced PCOS-like rats. Read More

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Advanced trophectoderm quality increases the risk of a large for gestational age baby in single frozen-thawed blastocyst transfer cycles.

Hum Reprod 2021 May 6. Epub 2021 May 6.

Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Study Question: Does trophectoderm (TE) quality affect birthweight after single frozen-thawed blastocyst transfer?

Summary Answer: Transfer of single blastocyst with advanced TE quality was associated with higher birthweight and increased risk of a large for gestational age (LGA) baby.

What Is Known Already: Transfer of blastocysts with advanced TE quality results in higher ongoing pregnancy rates and a lower miscarriage risk. However, data on the relationship between TE quality and birthweight are still lacking. Read More

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Proposing a deep learning-based method for improving the diagnostic certainty of pulmonary nodules in CT scan of chest.

Eur Radiol 2021 May 6. Epub 2021 May 6.

Deepwise AI Lab, Beijing, China.

Objective: To compare the performance of a deep learning (DL)-based method for diagnosing pulmonary nodules compared with radiologists' diagnostic approach in computed tomography (CT) of the chest.

Materials And Methods: A total of 150 pathologically confirmed pulmonary nodules (60% malignant) assessed and reported by radiologists were included. CT images were processed by the proposed DL-based method to generate the probability of malignancy (0-100%), and the nodules were divided into the groups of benign (0-39. Read More

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Gestational high-fat diet impaired demethylation of Pparα and induced obesity of offspring.

J Cell Mol Med 2021 May 6. Epub 2021 May 6.

The Key Laboratory of Reproductive Genetics (Zhejiang University School of Medicine), Ministry of Education, Hangzhou, China.

Gestational and postpartum high-fat diets (HFDs) have been implicated as causes of obesity in offspring in later life. The present study aimed to investigate the effects of gestational and/or postpartum HFD on obesity in offspring. We established a mouse model of HFD exposure that included gestation, lactation and post-weaning periods. Read More

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Promotion effects of microwave heating on coalbed methane desorption compared with conductive heating.

Sci Rep 2021 May 5;11(1):9618. Epub 2021 May 5.

State Key Laboratory Cultivation Base for Gas Geology and Gas Control (Henan Polytechnic University), Jiaozuo, Henan, People's Republic of China.

As a clean energy resource, coalbed methane (CBM) has drawn worldwide attention. However, the CBM reservoir has strong adsorption capacity and low permeability and thus requires stimulation. As a means to stimulate coalbed methane recovery, thermal injection faces geological and economic challenges because it uses conventional conductive heating (CH) to transfer heat. Read More

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Efficient solar light facilitated photo-oxidative detoxification of gaseous 2-chloroethyl ethyl sulfide on ZrO-doped g-CN under dry and humid air.

Chemosphere 2021 Apr 27;280:130685. Epub 2021 Apr 27.

Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, 03722, Republic of Korea. Electronic address:

Photo-oxidation of chemical warfare agents is considered a promising strategy to cope with threats from accidental or intentional release. In this study, heterostructure photocatalysts comprising different amounts of zirconium oxide (ZrO) over carbon nitride (CN) were synthesized via simple thermal exfoliation, followed by a precipitation method. The successful photocatalytic detoxification activity of the as-prepared photocatalyst was analyzed against 2-chloroethyl ethyl sulfide (CEES) under simulated solar light and natural sunlight irradiation in dry and humid air. Read More

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Accuracy and deviation analysis of robot-assisted spinal implants: A retrospective overview of 105 cases and preliminary comparison to open freehand surgery in lumbar spondylolisthesis.

Int J Med Robot 2021 May 4:e2273. Epub 2021 May 4.

Department of Spine Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

Background: Whether the accuracy of robot-assisted spinal screw placement is significantly higher than that of freehand and the source of robotic deviation remain unclear.

Methods: Clinical data of 105 patients who underwent robot-assisted spinal surgery was collected, and screw accuracy was evaluated by computed tomography according to the modified Gertzbein-Robbins classification. Patients were grouped by percutaneous and open surgery. Read More

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Recent Advances in the Plasma-Assisted Synthesis of Zinc Oxide Nanoparticles.

Nanomaterials (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

Department of Textiles, Graphic Arts and Design, Faculty of Natural Sciences and Engineering, University of Ljubljana, Aškerčeva 12, 1000 Ljubljana, Slovenia.

An overview of recent work on the low-temperature plasma-assisted synthesis of zinc oxide (ZnO) nanoparticles is presented and interpreted in terms of gas-phase and surface reactions with illustrated examples. The thermodynamical nonequilibrium conditions allow the formation of chemically reactive species with a potential energy of several eV, which readily interact with the Zn precursors and initiate reactions leading to the formation of nanoparticles or nanowires. The high-quality nanowires were synthesized from Zn powders only upon interaction with moderately ionized plasma in a narrow range of plasma parameters. Read More

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Validation of a Gas Chromatography-Mass Spectrometry Method for the Measurement of the Redox State Metabolic Ratios Lactate/Pyruvate and β-Hydroxybutyrate/Acetoacetate in Biological Samples.

Int J Mol Sci 2021 Apr 30;22(9). Epub 2021 Apr 30.

Service of Biochemistry and Molecular Genetics, Hospital Clinic Universitari, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Carrer de Villarroel 170, 08036 Barcelona, Spain.

The metabolic ratios lactate/pyruvate and β-hydroxybutyrate/acetoacetate are considered valuable tools to evaluate the in vivo redox cellular state by estimating the free NAD+/NADH in cytoplasm and mitochondria, respectively. The aim of the current study was to validate a gas-chromatography mass spectrometry method for simultaneous determination of the four metabolites in plasma and liver tissue. The procedure included an o-phenylenediamine microwave-assisted derivatization, followed by liquid-liquid extraction with ethyl acetate and silylation with bis(trimethylsilyl)trifluoroacetamide:trimethylchlorosilane 99:1. Read More

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Ethanol-assisted kneading of apigenin with arginine for enhanced dissolution rate of apigenin: development of rapidly disintegrating tablets.

Pharm Dev Technol 2021 May 6:1-8. Epub 2021 May 6.

Faculty of Pharmacy, Tanta University, Tanta, Egypt.

Apigenin is a natural flavonoid which is claimed to have many pharmacological activities ranging from simple anti-inflammatory to anticancer action. However, poor dissolution slowed the advancement of this drug through the development pipelines. The objective of this work was to probe ethanol-aided kneading of apigenin with arginine as a new strategy for enhanced dissolution rate. Read More

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Application of Spinal Robotic Navigation Technology to Minimally Invasive Percutaneous Treatment of Spinal Fractures: A Clinical, Non-Randomized, Controlled Study.

Orthop Surg 2021 May 4. Epub 2021 May 4.

Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.

Objective: To introduce a new robotic navigation system that assists pedicle screw implantation and verify the accuracy and stability of the system.

Methods: Pedicle screw placements were performed on the thoracic vertebrae (T)9-Lumbar vertebrae (L)5 thoracolumbar vertebrae of cadavers using robotic guidance. The operative duration, puncture success, correction, and correction time were assessed. Read More

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Spectroscopy-Assisted Label-free Molecular Analysis of Live Cell Surface with Vertically Aligned Plasmonic Nanopillars.

Small 2021 May 4:e2100161. Epub 2021 May 4.

Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.

A generalized label-free platform for surface-selective molecular sensing in living cells can transform the ability to examine complex events in the cell membrane. While vertically aligned semiconductor and metal-semiconductor hybrid nanopillars have rapidly surfaced for stimulating and probing the intracellular environment, the potential of such constructs for selectively interrogating the cell membrane is surprisingly underappreciated. In this work, a new platform, entitled nano-PROD (nano-pillar based Raman optical detection), enables molecular recording by probing fundamental vibrational modes of membrane constituents of cells adherent on a large-area silver-coated silicon nanopillar substrate fabricated using a precursor solution-based nanomanufacturing process. Read More

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Methyl-β-cyclodextrin and coronatine as new elicitors of tropane alkaloid biosynthesis in Atropa acuminata and Atropa belladonna hairy root cultures.

Physiol Plant 2021 May 3. Epub 2021 May 3.

Secció de Fisiologia i Biotecnologia Vegetal, Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Barcelona, Spain.

Hyoscyamine (HYO) and scopolamine (SCO) are tropane alkaloids acting as anticholinergic factors on the parasympathetic nervous system in humans and are produced by Solanaceous plants. Two strains of Agrobacterium rhizogenes, A4 and LBA9402, were used to infect Atropa acuminata Royle ex Miers and Atropa belladonna L. leaf explants. Read More

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Worker ants promote outbreeding by transporting young queens to alien nests.

Commun Biol 2021 May 3;4(1):515. Epub 2021 May 3.

Chair of Zoology and Evolutionary Biology - University of Regensburg, Regensburg, Germany.

Choosing the right mating partner is one of the most critical decisions in the life of a sexually reproducing organism and is the basis of sexual selection. This choice is usually assumed to be made by one or both of the sexual partners. Here, we describe a system in which a third party - the siblings - promote outbreeding by their sisters: workers of the tiny ant Cardiocondyla elegans carry female sexuals from their natal nest over several meters and drop them in the nest of another, unrelated colony to promote outbreeding with wingless, stationary males. Read More

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Ethical implications of AI in robotic surgical training: A Delphi consensus statement.

Eur Urol Focus 2021 Apr 30. Epub 2021 Apr 30.

Wellcome/ESPRC Centre for Interventional and Surgical Sciences (WEISS), University College London.

Context: As the role of AI in healthcare continues to expand there is increasing awareness of the potential pitfalls of AI and the need for guidance to avoid them.

Objectives: To provide ethical guidance on developing narrow AI applications for surgical training curricula. We define standardised approaches to developing AI driven applications in surgical training that address current recognised ethical implications of utilising AI on surgical data. Read More

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